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21.发明申请公开(公告)号：US20200087733A1
公开(公告)日：2020-03-19
申请号：US16494557
申请日：2018-03-08
Applicant: SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION , INDUSTRY-ACADEMIC COOPERATION FOUNDATION OF SUNCHON NATIONAL UNIVERSITY , SEOUL NATIONAL UNIVERSITY HOSPITAL
Inventor： Wonshik HAN , Dong-Young NOH , Han-Byoel LEE , Eun-Kyu KIM , Ae-Kyung PARK , Hyeong-Gon MOON
IPC: C12Q1/6886
Abstract: The present disclosure discloses a biomarker capable of predicting the therapeutic response to anticancer agents and prognosis of triple-negative breast cancer patients, and the use thereof. A biomarker according to the present disclosure allows the provision of optimized personal therapeutic methods through correct personalized treatment, contributing to the quality and prolongation of life of patients.
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公开(公告)号：US10570370B2
公开(公告)日：2020-02-25
申请号：US15506736
申请日：2015-08-27
Inventor： Sung Sup Park , Ji Yeon Kim
Abstract: Provided are a method of preparing retinal ganglion cells by differentiation of stem into retinal ganglion cells, retinal ganglion cells differentiated by the method, a method of screening for a death inhibitor or a proliferation promoter of retinal ganglion cells using the retinal ganglion cells differentiated by the method, a kit of screening for the death inhibitor or the proliferation promoter of retinal ganglion cells including the retinal ganglion cells differentiated by the method, a pharmaceutical composition for treating glaucoma or optic neuropathy including the retinal ganglion cells, a method of treating glaucoma or optic neuropathy including the step of administering the retinal ganglion cells to a subject suspected of having glaucoma or optic neuropathy, and a method of preparing a mature retinal ganglion cell line.
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公开(公告)号：US20250154501A1
公开(公告)日：2025-05-15
申请号：US18920353
申请日：2024-10-18
Inventor： Jong-il Kim , Jaeryuk Kim , Hyoung Jin Kang , Miyoung Park
Abstract: The present disclosure relates to a method of detecting an integration site of a vector in a genome. According to the method of the present disclosure, it is possible to simply and quickly analyze a quantitative integration site of a viral vector with respect to a plurality of DNA motifs (sites) in a genome. Therefore, it can be useful for monitoring the safety and effectiveness of a gene therapy agent.
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公开(公告)号：US20250134747A1
公开(公告)日：2025-05-01
申请号：US18931442
申请日：2024-10-30
Inventor： Jae Heung PARK , Seung Bin YOU , Eun Ho SUNG , Kee Won KIM , Sun Gun CHUNG
IPC: A61H3/00
Abstract: The gait assistance mechanism according to one example of the present invention may comprise one or more tendons connecting an upper limb, a trunk, and a lower limb of a wearer and a fixing part fixing the one or more tendons to the body of the wearer, and the one or more tendons may comprise a driving tendon connecting the lower limb and the upper limb on the same side of the wearer.
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25.发明公开公开(公告)号：US20240074827A1
公开(公告)日：2024-03-07
申请号：US18110825
申请日：2023-02-16
Inventor： Sungwan KIM , Minwoo CHO , Jonghyeon LEE , Young Gyun KIM , Byeong Soo KIM , Dan YOON
IPC: A61B34/37 , A61B90/00 , G06T19/00 , H04N13/117 , H04N13/344 , H04N13/383
CPC classification number: A61B34/37 , A61B90/37 , G06T19/00 , H04N13/117 , H04N13/344 , H04N13/383 , A61B2090/372 , G06T2210/41
Abstract: A headset of a surgical robot system includes an endoscope image transmission module configured to transmit an endoscope image to a main screen, a surgical assist function transmission module configured to transmit a selected and activated surgical assist function on an auxiliary screen positioned at one side of the main screen, a surgical assist function optional transmission module configured to transmit a list of a plurality of surgical assist functions to be provided on the auxiliary screen to a selection screen, an acceleration sensor and a gyroscope, configured to detect a change in a position of a head of a user, an eye tracking module configured to detect a change in a user gaze and a change in focus, and a controller configured to control a specific surgical assist function selected from among the plurality of surgical assist functions to be provided to the auxiliary screen.
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Patent Agency Ranking
26.发明公开公开(公告)号：US20230235402A1
公开(公告)日：2023-07-27
申请号：US18007182
申请日：2021-07-02
Applicant: SEOUL NATIONAL UNIVERSITY HOSPITAL , SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION , CHEONGJU UNIVERSITY INDUSTRY & ACADEMY COOPERATION FOUNDATION
Inventor： Hyun Chul JO , Young-il HWANG , Jin-Hee KIM , Jin-Hong KIM , Jae-Hyung LEE , Hyun-Ju LIM , Ah-Young LEE , Seung Yeon LEE , Ji-Hye YEA , Yeasol KIM
IPC: C12Q1/6883 , G01N33/68 , A61K38/17 , A61P21/00
CPC classification number: C12Q1/6883 , G01N33/6887 , A61K38/17 , A61P21/00 , C12Q2600/158 , G01N2800/10
Abstract: A composition suitable for diagnosing a musculoskeletal disease and a composition suitable for preventing or treating a musculoskeletal disease are disclosed. The composition contains zinc finger protein with KRAB and SCAN domains 8 (Zkscan8) protein, which can be effectively used as an excellent biomarker for obtaining accurate information about the occurrence and progression stages of a musculoskeletal disease, specifically a tendon disease or a ligament disease. The compositions containing Zkscan8 can be effectively used for preventing or treating a musculoskeletal disease through Zkscan8 overexpression.
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公开(公告)号：US20230165855A1
公开(公告)日：2023-06-01
申请号：US17912942
申请日：2021-03-19
Applicant: NOVMETAPHARMA CO., LTD. , SEOUL NATIONAL UNIVERSITY HOSPITAL , SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
Inventor： Hoe Yune JUNG , Heon Jong LEE , Yon Su KIM , Seung Hee YANG
IPC: A61K31/4985 , A61P9/12
CPC classification number: A61K31/4985 , A61P9/12
Abstract: New uses of Cyclo-HisPro (CHP) or a salt thereof for lowering blood pressure are disclosed. More specifically, the present invention relates to a pharmaceutical composition for lowering blood pressure, containing CHP or a salt thereof, and a functional health food composition containing CHP or a salt thereof; a method for lowering blood pressure using CHP or a salt thereof; a use of CHP or a salt thereof in the manufacture of antihypertensive agents; a pharmaceutical composition or a functional health food, for preventing or treating hypertension or complications thereof, containing CHP or a salt thereof; a method for preventing or treating hypertension or complications thereof by using CHP or a salt thereof; and a use of CHP or a salt thereof in the manufacture of a medicament for preventing or treating hypertension or complications thereof.
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公开(公告)号：US11568539B1
公开(公告)日：2023-01-31
申请号：US17857328
申请日：2022-07-05
Applicant: SEOUL NATIONAL UNIVERSITY HOSPITAL , Korea University Research and Business Foundation , Seoul National University R&DB Foundation , PLANIT Healthcare Inc.
Inventor： Jinwook Choi , Kyoungbun Lee , Gyeong Hoon Kang , Kyung Chul Moon , Gheeyoung Choe , Kyu Sang Lee , Jeong Hwan Park , Won-Ki Jeong , Se Young Chun , Youngkwan Kim
Abstract: Provided is a method of operating an apparatus for prostate cancer analysis operated by at least one processor, the method including: receiving digital slide images prepared from serial sections of a prostatectomy specimen, and a gross image of the serial sections; acquiring prostate cancer-related histological information of each received digital slide image using an artificial neural network model trained to infer histological information from the digital slide images; generating digital pathology images by displaying the prostate cancer-related histological information inferred from the artificial neural network model on each digital slide image; and providing a histological mapping image in which a tumor region extracted from each digital pathology image is mapped to a gross image of the corresponding section.
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公开(公告)号：US20220387208A1
公开(公告)日：2022-12-08
申请号：US17622925
申请日：2020-06-26
Inventor： Nam-Jong PAIK , Jihong PARK , Jae-Young LIM , Won-Seok KIM , Yong-Lae PARK , Junghan KWON
Abstract: A non-fixed shoulder brace is provided comprising: an affected shoulder support which is supported on an affected shoulder of a wearer; a waist support coupled to the wearer's waist; an affected arm mounting part in which the wearer's affected arm is inserted and which is supported by means of an affected shoulder strap member from the affected shoulder support; and an affected upper limb exercise assistance apparatus coupled to both ends of the waist support and disposed between the wearer's waist and the affected arm mounting part.
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公开(公告)号：US20180078620A1
公开(公告)日：2018-03-22
申请号：US15661300
申请日：2017-07-27
Applicant: INSTITUTE FOR BASIC SCIENCE , SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION , SEOUL NATIONAL UNIVERSITY HOSPITAL
Inventor： Jin-Soo KIM , Jeong Hun KIM , Sung Wook PARK , Kyoungmi KIM
CPC classification number: A61K38/465 , A61K48/00 , C12N15/102 , C12N15/11 , C12N15/1136 , C12N2310/20 , A61K2300/00
Abstract: Provided are a method of preventing and/or treating an eye disease, using a Cas9 protein and a guide RNA targeting VEGF-A, and a ribonucleoprotein including a Cas9 protein and a guide RNA targeting VEGF-A.
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