公开(公告)号：US20230285077A1

公开(公告)日：2023-09-14

申请号：US17617793

申请日：2021-11-11

Applicant: SPECLIPSE INC

Inventor： Sung Hyun PYUN ,  Wan Ki MIN

IPC: A61B18/20 ,  A61B18/04

CPC classification number: A61B18/203 ,  A61B18/042 ,  A61B2018/00452

Abstract: A laser irradiation device includes a housing which has an accommodation space formed therein and an opening formed in one side thereof, a laser module which is positioned in the accommodation space and outputs a pulsed beam having a predetermined focal length and a predetermined focal depth range through the opening, a guide member positioned at one side of the housing, and a contact member which is mounted on the guide member and includes a contact portion having a through-hole, through which the pulsed beam passes, formed therein, wherein the contact portion is in contact with a subject to assist in fixing an irradiation point of the pulsed beam, one end of the contact portion is positioned within the focal depth range such that plasma ablation is induced in at least a portion of the subject, and a diameter of the through-hole having a circular shape.

公开(公告)号：US20230234054A1

公开(公告)日：2023-07-27

申请号：US17702888

申请日：2022-03-24

Applicant: SPECLIPSE, INC.

Inventor： Sung Hyun PYUN ,  Wan Ki MIN

IPC: B01L3/00

CPC classification number: B01L3/502753 ,  B01L2300/0816 ,  B01L2300/0681

Abstract: A fluid separation apparatus is disclosed. The fluid separation apparatus includes a diluter which includes a first filter channel through which a fluid flows, a fluid structure formed to protrude outward from the first filter channel and including an air bag, and a first vibration generator configured to generate a first sound wave and which is configured to filter at least one substance included in the fluid based on a vortex of the fluid formed on an interface between the first filter channel and the air bag, and a separator which includes a second filter channel through which the diluted fluid flows, a second vibration generator configured to generate a second sound wave passing through the second filter channel, and a plurality of outlet channels branched from the second filter channel, wherein a plurality of substances included in the diluted fluid are separated based on the molecular weight.

公开(公告)号：US20230233155A1

公开(公告)日：2023-07-27

申请号：US17702903

申请日：2022-03-24

Applicant: SPECLIPSE, INC.

Inventor： Sung Hyun PYUN ,  Wan Ki MIN

IPC: A61B5/00

CPC classification number: A61B5/7264

Abstract: A liquid refining apparatus is disclosed. The liquid refining apparatus includes a substrate, a loader which is formed on the substrate and configured to receive a first liquid, a filter which is configured to reduce a concentration of at least one substance contained in the first liquid to obtain a second liquid with a reduced concentration of the at least one substance, a reactor which is configured to mix the second liquid with a reactant for target substance detection to obtain a third liquid containing, among a plurality of substances contained in the second liquid, a first substance which undergoes a predetermined reaction with the reactant and a second substance which does not undergo the predetermined reaction with the reactant, and a separator which is configured to separate the first substance and the second substance.

公开(公告)号：US20220381614A1

公开(公告)日：2022-12-01

申请号：US17883724

申请日：2022-08-09

Applicant: SPECLIPSE, INC.

Inventor： Sung Hyun PYUN ,  Wan Ki MIN

IPC: G01J3/443 ,  B63J2/14 ,  F02M21/02 ,  F17C6/00 ,  F17C9/02 ,  F17C9/04 ,  B63B25/16

Abstract: Disclosed herein are a method for diagnosing a disease of a body tissue by using LIBS (Laser-Induced Breakdown Spectroscopy) comprising: preparing a laser device including: a laser projection module, outputting the laser to a suspicious region of the body tissue, a light receiving module, receiving a plurality of light, a spectrum measurement module, and a guide unit; and projecting the laser to generate plasma by inducing tissue ablation in the suspicious region; wherein the laser projected to the suspicious region has a target area, and wherein the target area has smaller size than the suspicious region such that the target area is located inside the suspicious region.

公开(公告)号：US11422033B2

公开(公告)日：2022-08-23

申请号：US17135675

申请日：2020-12-28

Applicant: SPECLIPSE, Inc.

Inventor： Sung Hyun Pyun ,  Wan Ki Min

IPC: G01J3/30 ,  G01J3/443 ,  B63B25/16 ,  B63J2/14 ,  F02M21/02 ,  F17C6/00 ,  F17C9/02 ,  F17C9/04 ,  G01J3/42 ,  G01N21/71

Abstract: Disclosed herein are a method for diagnosing a disease of a body tissue by using LIBS (Laser-Induced Breakdown Spectroscopy) comprising: preparing a laser device including: a laser projection module, outputting the laser to a suspicious region of the body tissue, a light receiving module, receiving a plurality of light, a spectrum measurement module, and a guide unit; and projecting the laser to generate plasma by inducing tissue ablation in the suspicious region; wherein the laser projected to the suspicious region has a target area, and wherein the target area has smaller size than the suspicious region such that the target area is located inside the suspicious region.

公开(公告)号：US11326949B2

公开(公告)日：2022-05-10

申请号：US17084334

申请日：2020-10-29

Applicant: SPECLIPSE, Inc.

Inventor： Sung Hyun Pyun ,  Wan Ki Min

IPC: G01J3/30 ,  G01J3/443 ,  B63B25/16 ,  B63J2/14 ,  F02M21/02 ,  F17C6/00 ,  F17C9/02 ,  F17C9/04 ,  G01J3/42 ,  G01N21/71

Abstract: Disclosed herein are a diagnostic method using laser induced breakdown spectrum analysis and a diagnostic device for performing the same. The diagnostic device may include a laser projection module projecting a pulsed laser to a specimen, a light receiving module receiving a light generated by a plasma ablation induced at the specimen by the pulsed laser, a spectral member receiving and dividing the light generated by the plasma ablation; a sensor array including a plurality of sensors arranged to receive the divided light for each wavelength, and a controller obtaining spectrum data of the light generated by the plasma ablation from a specific exposure period, and determining whether or not the specimen is diseased based on the spectrum data of the light generated by the plasma ablation.

公开(公告)号：US20200300702A1

公开(公告)日：2020-09-24

申请号：US16863140

申请日：2020-04-30

Applicant: SPECLIPSE, Inc.

Inventor： Sung Hyun PYUN ,  Wan Ki MIN

IPC: G01J3/443

Abstract: Disclosed herein are a diagnostic method using laser induced breakdown spectrum analysis and a diagnostic device for performing the same. The diagnostic method may include projecting a pulsed laser to a suspicious specimen, obtaining first spectrum data on the light collected from the suspicious specimen, projecting the pulsed laser to a non-diseased specimen, obtaining second spectrum data on the light collected from the non-diseased specimen, and determining whether a disease is present in the suspicious specimen from a comparison value of the first spectrum data and the second spectrum data using an artificial neural network.

公开(公告)号：USD861165S1

公开(公告)日：2019-09-24

申请号：US29611431

申请日：2017-07-21

Applicant: Speclipse, Inc.

Designer： Sung Hyun Pyun ,  Wanki Min ,  Jin Woo Lee

公开(公告)号：US20190246908A1

公开(公告)日：2019-08-15

申请号：US16101928

申请日：2018-08-13

Applicant: Speclipse, Inc.

Inventor： Sung Hyun PYUN ,  Wanki MIN

IPC: A61B5/00 ,  G01J3/443 ,  G01J3/02 ,  G01N21/71 ,  G16H50/20

CPC classification number: A61B5/0084 ,  A61B5/0075 ,  A61B5/414 ,  A61B5/444 ,  G01J3/0218 ,  G01J3/443 ,  G01N21/718 ,  G16H50/20

Abstract: According to an embodiment of the present disclosure, there is provided a laser spectroscopy-based independent device, including: a spectrometer configured to measure a spectrum of generated light which is generated by a laser projected onto a sample; and a disease analysis module configured to determine whether there is lesion tissue by applying a lesion tissue detection learning model to a result of non-discrete spectrum measurement, which is measured by the spectrometer, wherein the spectrometer is configured to measure spectra of all generated light that is generated from a time when the laser is projected onto the sample.

公开(公告)号：US20190029520A1

公开(公告)日：2019-01-31

申请号：US15810803

申请日：2017-11-13

Applicant: Speclipse, Inc.

Inventor： Sung Hyun PYUN ,  Wanki MIN

IPC: A61B5/00 ,  G02B27/40 ,  G02B27/09

Abstract: According to one embodiment, a tip for a laser handpiece includes: a light radiating module configured to radiate a laser toward a target; and a light receiving module configured to receive at least a portion of light which is generated by the laser radiated onto the target as received light. The light radiating module includes: a base which has an inner space formed therein to allow the laser to pass therethrough; a fixing portion which is coupled to a lower portion of the base and has a penetrating hole formed therein to allow the laser to pass therethrough; and a module connecting member which is interposed and fixed between the base and the fixing portion.