公开(公告)号：US20110275951A1

公开(公告)日：2011-11-10

申请号：US13142432

申请日：2010-01-07

申请人： Oliver Lips ,  Bernd David ,  Sascha Krueger ,  Steffen Weiss

发明人： Oliver Lips ,  Bernd David ,  Sascha Krueger ,  Steffen Weiss

IPC分类号： A61B5/053 ,  A61B5/04

CPC分类号： A61B5/0422

摘要： The invention relates to electrophysiology catheter systems and their use, such as in an MRI environment, and in particular to analysis of electric signals from such. An electrophysiology (EP) catheter with a plurality of electrically isolated electrode segments arranged in longitudinally spaced bands around the catheter is used to detect electric signals. A workstation receives the electrical signals which are then processed by a processing unit. Electric signals from electrode segments can be used to determine roll angle information of the catheter in relation to patient anatomy by determining signals from electrode segments in contact with tissue. Also, electric signals can be used to extract a reference signal that can be used to correct for gradient induced artefacts.

摘要翻译： 本发明涉及电生理学导管系统及其用途，例如在MRI环境中，特别涉及从其中分析电信号。 使用具有多个电隔离电极段的电生理学（EP）导管，其围绕导管以纵向间隔的带布置，以检测电信号。 工作站接收然后由处理单元处理的电信号。 来自电极段的电信号可用于通过确定与组织接触的电极段的信号来确定导管相对于患者解剖结构的侧倾角信息。 此外，电信号可以用于提取可用于校正梯度诱导伪像的参考信号。

公开(公告)号：US20110257512A1

公开(公告)日：2011-10-20

申请号：US13141096

申请日：2009-11-23

申请人： Sascha Krueger

发明人： Sascha Krueger

IPC分类号： A61B5/05 ,  A61N7/00

CPC分类号： A61B18/1492 ,  A61B90/06 ,  A61B90/36 ,  A61B2017/00084 ,  A61B2017/00243 ,  A61B2017/22067 ,  A61B2090/374 ,  A61B2090/3954 ,  A61N7/022

摘要： An interventional instrument (24) for use in performing an interventional procedure includes: a balloon (30) disposed proximate to a tip of the interventional instrument that inflates and anchors in a lumen of a fluid conduit during the interventional procedure; and one or more susceptibility markers (34) disposed proximate to the tip of the interventional instrument. A magnetic resonance scanner (10) is configured to image at least the tip of the interventional instrument during the interventional procedure using a magnetic resonance imaging sequence in which fluid flow (40) through the fluid conduit past the inflated balloon produces an extended magnetic resonance image artifact (42).

摘要翻译： 用于执行介入手术的介入器械（24）包括：靠近介入器械的尖端布置的球囊（30），其在介入手术过程中使流体导管的内腔膨胀并锚固; 以及设置在介入器械的尖端附近的一个或多个敏感性标记（34）。 磁共振扫描器（10）被配置为使用磁共振成像序列在介入手术过程中至少对介入器械的尖端进行成像，其中通过流体导管的经过充气气囊的流体流（40）产生延伸的磁共振图像 神器（42）。

公开(公告)号：US20110257511A1

公开(公告)日：2011-10-20

申请号：US13141092

申请日：2009-11-23

申请人： Sascha Krueger

发明人： Sascha Krueger

IPC分类号： A61B5/055

CPC分类号： G01R33/34084 ,  A61B5/055 ,  G01R33/3628

摘要： A handpiece (32) defines a bore (62) in which a proximal end (56) of a catheter or other interventional instrument (30) is received. An insulating support (70) supports an interventional instrument which carries an interventional instrument winding (54) in, but spaced from, the internal bore (62). A handpiece winding (64) disposed along the bore interacts with the transmission line winding (54) to form an inductive coupling with the transmission line. After the handpiece is slid axially to adjust the inductive coupling between the windings (54, 64), a locking mechanism functions in such a manner that the interventional instrument is inhibited from axial sliding motion relative to the handpiece while permitting rotation of the interventional instrument relative to the handpiece thus maintaining the inductive coupling while allowing optimal handling of the device.

摘要翻译： 手柄（32）限定出孔（62），其中接收导管或其他介入器械（30）的近端（56）。 绝缘支撑件（70）支撑介入仪器，所述介入仪器携带介入式仪器绕组（54），但与内孔（62）间隔开。 沿着孔布置的手持绕组（64）与传输线绕组（54）相互作用以形成与传输线的感应耦合。 在手柄滑动以调节绕组（54,64）之间的感应耦合之后，锁定机构以这样一种方式起作用，使得介入器械被禁止相对于手持件的轴向滑动运动，同时允许介入器械相对 从而保持感应耦合，同时允许设备的最佳处理。

公开(公告)号：US07969142B2

公开(公告)日：2011-06-28

申请号：US11996617

申请日：2006-07-12

申请人： Sascha Krueger ,  Bernhard Gleich

发明人： Sascha Krueger ,  Bernhard Gleich

IPC分类号： G01B7/14 ,  A61B5/05

CPC分类号： G01D5/208 ,  G01D5/2073

摘要： A system and method for determining the location of a remote object connected to an induction coil using a magnetic tracking sensor. The system and method include locating a magnetic core asymmetrically disposed within the induction coil located near the remote object, and operably connecting a single DC electrical circuit o ends defining the induction coil. The DC electrical circuit provides a DC current to the induction coil while the induction coil is disposed in an external AC magnetic field. The DC current adjusts the level of saturation of the magnetic core, and hence varies a response signal of the induction coil disposed in the external AC magnetic field to provide magnetic tracking of the induction coil.

摘要翻译： 一种用于使用磁跟踪传感器确定连接到感应线圈的远程物体的位置的系统和方法。 该系统和方法包括定位不对称地设置在位于远程物体附近的感应线圈内的磁芯，并且可操作地连接限定感应线圈的单个DC电路o端。 直流电路在感应线圈设置在外部交流磁场中时，向感应线圈提供直流电流。 直流电流调节磁芯的饱和水平，因此改变设置在外部交流磁场中的感应线圈的响应信号，以提供感应线圈的磁跟踪。

公开(公告)号：US20100312091A1

公开(公告)日：2010-12-09

申请号：US12808404

申请日：2008-12-22

申请人： Sascha Krueger ,  Daniel Wirtz ,  Steffen Weiss

发明人： Sascha Krueger ,  Daniel Wirtz ,  Steffen Weiss

IPC分类号： A61B5/055 ,  G08B23/00

CPC分类号： G01R33/285 ,  G01R33/288

摘要： A magnetic resonance method comprises applying a radio frequency excitation in an examination region (14), measuring a magnetic resonance signal generated by the applied radio frequency excitation in a subject (16) in the examination region, monitoring a radio frequency parameter during the applying, and evaluating subject safety based on the monitoring. A magnetic resonance safety monitor (40) comprises an analyzer (42, 44, 46, 50) configured to (i) receive a radio frequency signal during magnetic resonance excitation, (ii) extract a radio frequency parameter from the received radio frequency signal, and (iii) evaluate subject safety based on the extracted radio frequency parameter, and a remediation module (54) configured to perform a remediation of the magnetic resonance excitation responsive to the evaluation (iii) indicating a potentially unsafe condition.

摘要翻译： 磁共振方法包括在检查区域（14）中施加射频激励，测量由所述检查区域中的被检体（16）施加的射频激励产生的磁共振信号，在施加期间监视射频参数， 并根据监测评估受试者的安全性。 磁共振安全监视器（40）包括分析器（42,44,46,50），其被配置为（i）在磁共振激励期间接收射频信号，（ii）从所接收的射频信号中提取射频参数， 以及（iii）基于提取的射频参数来评估对象安全性;以及修复模块（54），其被配置为响应于指示潜在不安全状况的评估（iii）来执行磁共振激励的修复。

公开(公告)号：US20100094123A1

公开(公告)日：2010-04-15

申请号：US12524001

申请日：2008-01-24

申请人： Oliver Lips ,  Bernd David ,  Sascha Krueger ,  Steffen Weiss

发明人： Oliver Lips ,  Bernd David ,  Sascha Krueger ,  Steffen Weiss

IPC分类号： A61B5/05

CPC分类号： G01R33/287 ,  G01R33/288 ,  G01R33/3628

摘要： The present invention relates to an electrically conductive transmission line for transmitting RF signals, in particular for transmitting MR signals between a transmission and/or receiving coil (11) and a transmitting and/or receiving unit (12), by which separate known matching networks can be avoided or reduced. A transmission line is proposed comprising a plurality of lead segments (31) coupled only by transformers (32, 33) having a transformer impedance ZL placed between two neighbouring lead segments, wherein for power matching of the two transformers (32, 33) placed at opposite ends of a lead segment (31) said lead segment (31) has a low lead segment impedance Zo and/or a high dielectric constant εr and wherein said lead segment (31) has a short length 1. Thus, the lead segments themselves provide the matching of the transformers, and separate matching circuits are no longer needed.

摘要翻译： 本发明涉及一种用于发送RF信号的导电传输线，特别是用于在发射和/或接收线圈（11）与发射和/或接收单元（12）之间发射MR信号，通过该传输线单独的已知匹配网络 可以避免或减少。 提出一种传输线，其包括多个引线段（31），其仅由放置在两个相邻引线段之间的变压器阻抗ZL的变压器（32,33）耦合，其中为了将两个变压器（32,33）的功率匹配放置在 引线段（31）的相对端，所述引线段（31）具有低引线段阻抗Zo和/或高介电常数ε，并且其中所述引线段（31）具有短的长度1.因此，引线 段本身提供变压器的匹配，不再需要单独的匹配电路。

公开(公告)号：US20080294034A1

公开(公告)日：2008-11-27

申请号：US10597984

申请日：2005-02-18

申请人： Sascha Krueger ,  Holger Timinger ,  Joerg Sabczynski ,  Joern Borgert

发明人： Sascha Krueger ,  Holger Timinger ,  Joerg Sabczynski ,  Joern Borgert

IPC分类号： A61B5/06 ,  A61B5/05

CPC分类号： A61B5/06 ,  A61B5/062 ,  A61B6/12 ,  A61B34/20 ,  A61B90/36 ,  A61B2034/2051 ,  A61B2090/3958

摘要： The invention relates to a device and a method for the determination of the position of a catheter in a vascular system (8). In this, the measured positions (r1, r2) of two magnetic localizers at the tip of a catheter are displaced by correction vectors (k1, k2) while optimizing a quality dimension. The quality dimension includes a component taking account both of the deviation of the measured positions (r1, r2) from the vascular layout and of the deviation of the associated orientation (r2−r1) from the orientation of the vascular layout according to a vascular map. In addition, the quality dimension may include components which evaluate the measured shape of the catheter compared to the vascular map. An additional correction step can further ensure that the corrected positions (r1′, r2″) correspond to the preset fixed distance (d) of the localizers (4, 5).

摘要翻译： 本发明涉及一种用于确定导管在血管系统（8）中的位置的装置和方法。 在此，在优化质量维度的同时，通过校正矢量（k1，k2）使导管尖端处的两个定位器的测量位置（r1，r2）移位。 质量维度包括考虑到血管布局的测量位置（r1，r2）的偏差和相关联取向（r2-r1）与血管布局的取向（根据血管图）的偏差的分量 。 此外，质量维度可以包括与血管图相比评估导管的测量形状的组件。 附加的校正步骤还可以确保校正位置（r1'，r2“）对应于定位器（4,5）的预设固定距离（d）。

公开(公告)号：US09638769B2

公开(公告)日：2017-05-02

申请号：US14233811

申请日：2012-07-16

申请人： Daniel Wirtz ,  Christoph Leussler ,  Sascha Krueger

发明人： Daniel Wirtz ,  Christoph Leussler ,  Sascha Krueger

IPC分类号： G01V3/00 ,  G01R33/28 ,  G01R33/58

CPC分类号： G01R33/28 ,  G01R33/287 ,  G01R33/58

摘要： A fiducial position marker (1) for use in a magnetic resonance (MR) imaging apparatus is disclosed for exciting and/or receiving MR signals in/from a local volume which at least substantially surrounds or adjoins the position marker, in order to determine and/or image from these MR signals the position of the position marker in an MR image of an examination object. Such a position marker (1) is especially used for determining and/or imaging a position of an interventional or non-interventional instrument to which the position marker may be attached, like a catheter, a surgical device, a biopsy needle, a pointer, a stent or another invasive or any non-invasive device in an MR image of an examination object. Further, a position marker system comprising such a position marker (1) and a circuit arrangement (5, 6, 6a, 8) for driving the position marker (1) for exciting MR signals and/or for processing MR signals received by the position marker is disclosed.

公开(公告)号：US20120203100A1

公开(公告)日：2012-08-09

申请号：US13503084

申请日：2010-10-25

申请人： Steffen Weiss ,  Sascha Krueger

发明人： Steffen Weiss ,  Sascha Krueger

IPC分类号： A61B5/055 ,  A61B18/00

CPC分类号： A61N1/06 ,  A61B5/0422 ,  A61B18/1492 ,  A61B2017/00084 ,  A61B2018/00023 ,  A61B2018/00029 ,  A61B2018/00791 ,  A61B2090/374 ,  A61N1/086 ,  G01R33/285 ,  G01R33/288

摘要： A catheter comprising:-a transmission line (104, 106, 924, 1202, 1302, 1902,), wherein the transmission line comprises a plurality of radio frequency traps (118, 318, 418, 518, 618, 718, 818, 918, 1018, 1202, 1404,); and-a cooling line (104, 304, 1200, 1900) for cooling the plurality of radio frequency traps with a fluid.

摘要翻译： 一种导管，包括： - 传输线（104,106,924,1202,1201,1902），其中所述传输线包括多个无线电频率陷阱（118,318,418,518,618,718,818,918） ，1018，1202，1404，）; 和用于用流体冷却多个射频陷阱的冷却管线（104,304,1200,1900）。

公开(公告)号：US20120086449A1

公开(公告)日：2012-04-12

申请号：US13260918

申请日：2010-03-31

申请人： Ingmar Graesslin ,  Sascha Krueger

发明人： Ingmar Graesslin ,  Sascha Krueger

IPC分类号： G01R33/44 ,  G01R33/32

CPC分类号： G01R33/285 ,  G01R33/288

摘要： A magnetic resonance method comprises: performing (C1) a magnetic resonance procedure on a calibration subject including an implant device; detecting (C2) a pick-up coil (PUC) signal at least during a radio frequency transmit phase of operation (C1); performing (C3) three dimensional temperature mapping of the calibration subject using a magnetic resonance sequence configured to detect any temperature change induced in any part of the implant device by operation (C1); generating (C4) an unsafe condition criterion (30) for the detected PUC signal based on correlating a PUC signal characteristic detected by operation (C2) with a temperature change detected by operation (C3); performing (M5) the magnetic resonance procedure on a subject containing an implant device; detecting (M6) a PUC signal at least during a radio frequency transmit phase of operation (M5); and monitoring (M7) for an unsafe condition indicated by the PUC signal detected in operation (M6) satisfying the unsafe condition criterion (30).

摘要翻译： 磁共振方法包括：对包括植入装置的校准对象执行（C1）磁共振程序; 至少在射频发射阶段（C1）期间检测（C2）拾波线圈（PUC）信号; 使用构造成通过操作（C1）检测在植入装置的任何部分中诱导的任何温度变化的磁共振序列来执行（C3）校准对象的三维温度映射; 基于通过操作（C2）检测到的PUC信号特性与由操作（C3）检测到的温度变化相关联，生成（C4）用于检测到的PUC信号的不安全条件标准（30）。 对包含植入装置的受试者执行（M5）磁共振程序; 至少在射频发射阶段（M5）期间检测（M6）PUC信号; 以及对满足不安全条件标准（30）的在操作中检测到​​的PUC信号（M6）指示的不安全状态进行监视（M7）。