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公开(公告)号:US4468462A
公开(公告)日:1984-08-28
申请号:US452168
申请日:1982-12-22
申请人: Nancy E. Malin , Jeffrey T. Fayerman , Michael D. Jones , James A. Mabe , Walter M. Nakatsukasa
发明人: Nancy E. Malin , Jeffrey T. Fayerman , Michael D. Jones , James A. Mabe , Walter M. Nakatsukasa
CPC分类号: C12N15/76 , Y10S435/886 , Y10S435/889 , Y10S435/896
摘要: The present invention discloses selectable recombinant DNA cloning vectors for use in Streptomyces.
摘要翻译: 本发明公开了用于链霉菌的选择性重组DNA克隆载体。
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公开(公告)号:US4174404A
公开(公告)日:1979-11-13
申请号:US955448
申请日:1978-10-27
IPC分类号: C07D493/10 , C12P17/18 , A61K31/35
CPC分类号: C07D493/10 , C12P17/181 , C12R1/485
摘要: Deoxynarasin antibiotic complex, comprising 20-deoxynarasin and 20-deoxy-epi-17-narasin, is produced by submerged aerobic fermentation of Streptomyces aureofaciens NRRL 11181. 20-Deoxynarasin and 20-deoxy-epi-17-narasin are separated and isolated by chromatography. The deoxynarasin complex, 20-deoxynarasin and 20-deoxy-epi-17-narasin are antibacterial and anticoccidial agents and also increase feed-utilization efficiency in ruminants. 20-Deoxynarasin and its salts are cardiotonic agents.
摘要翻译: 通过潜在链霉菌(Streptomyces aureafaciens)NRRL 11181的潜在好氧发酵产生含有脱氧镰刀菌素和20-脱氧表面-17-纳沙星的脱氧镰刀菌素抗生素复合物。通过色谱法分离和分离20-脱氧n as素和20-脱氧表i -17- n as素 。 脱氧镰刀菌素复合物,20-脱氧ar as素和20-脱氧表i -17- n in素是抗菌和抗球虫剂,也提高反刍动物的饲料利用效率。 20-Deoxynarasin及其盐是强心剂。
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