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公开(公告)号:US11739157B2
公开(公告)日:2023-08-29
申请号:US16762895
申请日:2018-11-09
Inventor: Peter Brauer , John Edward Connolly , Richard Hopkins , Junyun Lai , Jianrong Lionel Low , Kar Wai Tan , Cheng-l Wang , Siok Ping Yeo
CPC classification number: C07K16/2866 , A61P35/00 , C07K16/468 , C07K2317/565 , C07K2317/75
Abstract: Antigen binding molecules capable of binding to CD122 and/or common γ chain (CD132) are disclosed herein. Also disclosed are compositions comprising such antigen binding molecules, and uses and methods using the same.
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公开(公告)号:US11534489B2
公开(公告)日:2022-12-27
申请号:US16597586
申请日:2019-10-09
Applicant: Agency for Science, Technology and Research
Inventor: Cheng-i Wang , Hsueh Ling Janice Oh , Siok Ping Yeo
IPC: A61K39/395 , C07K16/28 , A61K45/06 , C07K14/705 , G01N33/53 , G01N33/574 , A61K39/00
Abstract: Anti-PD-L1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and uses and methods using the same.
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公开(公告)号:US11267887B2
公开(公告)日:2022-03-08
申请号:US16099652
申请日:2017-04-13
Applicant: Agency For Science, Technology and Research
Inventor: Cheng-I Wang , Eve Ngoh , Siok Ping Yeo
IPC: A61K39/395 , A61K39/00 , C07K16/42 , C07K16/46 , C07K16/28 , A61K9/00 , A61P31/00 , A61P35/00 , A61K35/17 , C12N5/0783 , C12N15/85 , G01N33/574
Abstract: Anti-CTLA-4 antibodies are disclosed. Also disclosed are compositions comprising such antibodies, and uses and methods using the same.
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公开(公告)号:US10696747B2
公开(公告)日:2020-06-30
申请号:US16112008
申请日:2018-08-24
Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventor: Cheng-I Wang , Peter Brauer , Siok Ping Yeo , Hwee Ching Tan , John Edward Connolly
Abstract: Anti-CD122 and/or γc antibodies and fragments thereof are disclosed. Also disclosed are compositions comprising such antibodies and fragments, and uses and methods using the same.
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公开(公告)号:US10259874B2
公开(公告)日:2019-04-16
申请号:US15521685
申请日:2015-10-27
Applicant: Agency for Science, Technology and Research
Inventor: Cheng-I Wang , Hsueh Ling Janice Oh , Siok Ping Yeo , Yun Pei Sharon Goh
Abstract: Anti-TIM-3 antibodies are disclosed, as well as pharmaceutical compositions comprising such antibodies, and uses and methods using the same, such as in the treatment of cancer, infectious diseases, or T-cell dysfunctional disorders. Bispecific antibodies against TIM-3 and other targets are also disclosed, with preferred embodiment of a bispecific antibody against TIM-3 and CD3.
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公开(公告)号:US10167338B2
公开(公告)日:2019-01-01
申请号:US15229336
申请日:2016-08-05
Applicant: Agency for Science, Technology and Research
Inventor: Cheng-I Wang , Peter Brauer , Siok Ping Yeo , Hwee Ching Tan , John Edward Connolly
Abstract: Anti-CD122 and/or γc antibodies and fragments thereof are disclosed. Also disclosed are compositions comprising such antibodies and fragments, and uses and methods using the same.
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公开(公告)号:US09758583B2
公开(公告)日:2017-09-12
申请号:US15486468
申请日:2017-04-13
Applicant: Agency for Science, Technology and Research
Inventor: Cheng-I Wang , Eve Ngoh , Siok Ping Yeo
CPC classification number: C07K16/2818 , A61K9/0019 , A61K2039/505 , C07K2317/33 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92 , C07K2319/00
Abstract: Anti-CTLA-4 antibodies are disclosed. Also disclosed are compositions comprising such antibodies, and uses and methods using the same.
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公开(公告)号:US11912761B2
公开(公告)日:2024-02-27
申请号:US17150689
申请日:2021-01-15
Applicant: Agency for Science, Technology and Research
Inventor: Cheng-I Wang , Angeline Goh , Siok Ping Yeo , Alessandra Rosa Mortellaro , Subhra Kumar Biswas , Florent Ginhoux , Pingyu Zhong
IPC: A61K39/395 , C07K16/24 , A61K39/00
CPC classification number: C07K16/245 , A61K39/3955 , A61K2039/505 , C07K2317/10 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The present invention is directed to antigen binding proteins and in particular to IL-1β antigen binding proteins. The present invention further provides compositions comprising the antigen binding proteins, use of the antigen binding proteins and methods for production.
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公开(公告)号:US11780913B2
公开(公告)日:2023-10-10
申请号:US17061194
申请日:2020-10-01
Applicant: Agency for Science, Technology and Research
Inventor: Cheng-I Wang , Angeline Goh , Siok Ping Yeo , Alessandra Rosa Mortellaro , Subhra Kumar Biswas , Florent Ginhoux , Pingyu Zhong
IPC: A61K39/395 , C07K16/24 , A61K39/00
CPC classification number: C07K16/245 , A61K39/3955 , A61K2039/505 , C07K2317/10 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The present invention is directed to antigen binding proteins and in particular to IL-1β antigen binding proteins. The present invention further provides compositions comprising the antigen binding proteins, use of the antigen binding proteins and methods for production.
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公开(公告)号:US11702471B2
公开(公告)日:2023-07-18
申请号:US17150691
申请日:2021-01-15
Applicant: Agency for Science, Technology and Research
Inventor: Cheng-I Wang , Angeline Goh , Siok Ping Yeo , Alessandra Rosa Mortellaro , Subhra Kumar Biswas , Florent Ginhoux , Pingyu Zhong
IPC: C07K16/24 , A61K39/395 , A61K39/00
CPC classification number: C07K16/245 , A61K39/3955 , A61K2039/505 , C07K2317/10 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92
Abstract: The present invention is directed to antigen binding proteins and in particular to IL-1β antigen binding proteins. The present invention further provides compositions comprising the antigen binding proteins, use of the antigen binding proteins and methods for production.
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