-
公开(公告)号:US20230201345A1
公开(公告)日:2023-06-29
申请号:US18058699
申请日:2022-11-23
Applicant: Agency for Science, Technology and Research
Inventor: Cheng-I Wang , Hsueh Ling Janice Oh , Siok Ping Yeo
IPC: A61K39/395 , C07K16/28 , A61K45/06 , C07K14/705 , G01N33/53 , G01N33/574
CPC classification number: A61K39/3955 , C07K16/2827 , A61K39/395 , A61K45/06 , C07K14/70532 , G01N33/53 , G01N33/57484 , C07K2317/33 , C07K2317/55 , C07K2317/567 , C07K2317/76 , C07K2317/92 , C07K2317/21 , A61K2039/505
Abstract: Anti-PD-L1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and uses and methods using the same.
-
公开(公告)号:US20180002423A1
公开(公告)日:2018-01-04
申请号:US15542023
申请日:2016-01-04
Applicant: Agency for Science, Technology and Research
Inventor: Cheng-i Wang , Hsueh Ling Janice Oh , Siok Ping Yeo
IPC: C07K16/28 , A61K39/395
CPC classification number: A61K39/3955 , A61K39/395 , A61K45/06 , A61K2039/505 , C07K14/70532 , C07K16/2827 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/567 , C07K2317/622 , C07K2317/76 , C07K2317/92 , C07K2319/30 , G01N33/53 , G01N33/57484 , G01N2800/52 , Y02A50/41 , Y02A50/412
Abstract: Anti-PD-L1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and methods of using such antibodies to restore T-cell function in T-cells exhibiting T-cell exhaustion or T-cell anergy.
-
公开(公告)号:US20170306016A1
公开(公告)日:2017-10-26
申请号:US15521514
申请日:2015-10-27
Applicant: Agency for Science, Technology and Research
Inventor: Cheng-i Wang , Hsueh Ling Janice Oh , Siok Ping Yeo , Yun Pei Sharon Goh
IPC: C07K16/28 , A61K39/395
CPC classification number: C07K16/2803 , A61K39/395 , C07K16/28 , C07K16/2809 , C07K2317/31 , C07K2317/622
Abstract: Anti-TIM-3 antibodies are disclosed, as well as pharmaceutical compositions comprising such antibodies, and uses and methods using the same, such as in the treatment of cancer or infectious disease or T-cell dysfunctional disorders. Bispecific antibodies against TIM-3 and other targets are also disclosed, with a preferred embodiment of a bispecific antibody against TIM-3 and CD3.
-
公开(公告)号:US09789183B1
公开(公告)日:2017-10-17
申请号:US15623679
申请日:2017-06-15
Applicant: Agency for Science, Technology and Research
Inventor: Cheng-I Wang , Hsueh Ling Janice Oh , Siok Ping Yeo
IPC: A61K39/395 , C07K16/28 , A61K45/06 , C07K14/705 , G01N33/53 , G01N33/574
CPC classification number: A61K39/3955 , A61K39/395 , A61K45/06 , A61K2039/505 , C07K14/70532 , C07K16/2827 , C07K2317/21 , C07K2317/33 , C07K2317/34 , C07K2317/54 , C07K2317/55 , C07K2317/567 , C07K2317/622 , C07K2317/76 , C07K2317/92 , C07K2319/30 , G01N33/53 , G01N33/57484 , G01N2800/52 , Y02A50/41 , Y02A50/412
Abstract: Anti-PD-L1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and uses and methods using the same.
-
公开(公告)号:US09771425B2
公开(公告)日:2017-09-26
申请号:US15495048
申请日:2017-04-24
Applicant: Agency for Science, Technology and Research
Inventor: Cheng-i Wang , Hsueh Ling Janice Oh , Siok Ping Yeo , Jianrong Lionel Low , Hwee Ching Tan
IPC: C07K16/28
CPC classification number: C07K16/2818 , A61K2039/505 , C07K16/005 , C07K2317/31 , C07K2317/33 , C07K2317/51 , C07K2317/515 , C07K2317/565 , C07K2317/92
Abstract: Anti-PD-1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and uses and methods using the same.
-
公开(公告)号:US20170240635A1
公开(公告)日:2017-08-24
申请号:US15495048
申请日:2017-04-24
Applicant: Agency for Science, Technology and Research
Inventor: Cheng-i Wang , Hsueh Ling Janice Oh , Siok Ping Yeo , Jianrong Lionel Low , Hwee Ching Tan
IPC: C07K16/28
CPC classification number: C07K16/2818 , A61K2039/505 , C07K16/005 , C07K2317/31 , C07K2317/33 , C07K2317/51 , C07K2317/515 , C07K2317/565 , C07K2317/92
Abstract: Anti-PD-1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and uses and methods using the same.
-
公开(公告)号:US11072659B2
公开(公告)日:2021-07-27
申请号:US16360445
申请日:2019-03-21
Applicant: Agency for Science, Technology and Research
Inventor: Cheng-I Wang , Hsueh Ling Janice Oh , Siok Ping Yeo , Jianrong Lionel Low , Hwee Ching Tan
Abstract: Anti-PD-1 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and uses and methods using the same.
-
公开(公告)号:US10919962B2
公开(公告)日:2021-02-16
申请号:US16192537
申请日:2018-11-15
Applicant: Agency for Science, Technology and Research
Inventor: Cheng-I Wang , Angeline Goh , Siok Ping Yeo , Alessandra Rosa Mortellaro , Subhra Kumar Biswas , Florent Ginhoux , Pingyu Zhong
IPC: A61K39/395 , C07K16/24 , A61K39/00
Abstract: The present invention is directed to antigen binding proteins and in particular to IL-1β antigen binding proteins. The present invention further provides compositions comprising the antigen binding proteins, use of the antigen binding proteins and methods for production.
-
公开(公告)号:US10472423B2
公开(公告)日:2019-11-12
申请号:US15908218
申请日:2018-02-28
Applicant: AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
Inventor: Cheng-I Wang , Peter Brauer , Siok Ping Yeo , Hwee Ching Tan , John Edward Connolly
IPC: A61K39/395 , C07K16/28 , C07K16/24 , A61P35/00 , C12N5/0783 , A61K38/20 , A61K39/00
Abstract: Anti-CD122 and/or γc antibodies and fragments thereof are disclosed. Also disclosed are compositions comprising such antibodies and fragments, and uses and methods using the same.
-
公开(公告)号:US20190185564A1
公开(公告)日:2019-06-20
申请号:US16294474
申请日:2019-03-06
Applicant: Agency for Science, Technology and Research
Inventor: Cheng-I Wang , Hsueh Ling Janice Oh , Siok Ping Yeo , Yun Pei Sharon Goh
CPC classification number: C07K16/2803 , C07K16/2809 , C07K16/3061 , C07K16/468 , C07K2317/21 , C07K2317/31 , C07K2317/565 , C07K2317/622 , C07K2317/732 , C07K2317/92
Abstract: Anti-TIM-3 antibodies are disclosed. Also disclosed are pharmaceutical compositions comprising such antibodies, and uses and methods using the same.
-
-
-
-
-
-
-
-
-