公开(公告)号：US20200040350A1

公开(公告)日：2020-02-06

申请号：US16529365

申请日：2019-08-01

Applicant: Altria Client Services LLC

Inventor： Chengalrayan Kudithipudi ,  Jaemo Yang ,  Yanxin Shen ,  Dongmei Xu ,  Ujwala Warek ,  James Strickland ,  Jesse Frederick

IPC: C12N15/82

Abstract: The present disclosure provides the identification of promoters that are preferentially active in tobacco axillary buds. Also provided are tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing tobacco plants comprising reduced or no sucker growth.

公开(公告)号：US20190300893A1

公开(公告)日：2019-10-03

申请号：US16372833

申请日：2019-04-02

Applicant: Altria Client Services LLC

Inventor： Chengalrayan Kudithipudi ,  Dongmei Xu ,  James Strickland ,  Yanxin Shen

IPC: C12N15/82 ,  A24B15/10

Abstract: The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radical absorbance capacity (ORAC), increase phenylalanine, or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.

公开(公告)号：US20160281100A1

公开(公告)日：2016-09-29

申请号：US14875928

申请日：2015-10-06

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Chengalrayan Kudithipudi ,  Yanxin Shen ,  Dongmei Xu ,  Jesse Frederick ,  Jaemo Yang

IPC: C12N15/82 ,  A24B15/10 ,  C12N15/01

CPC classification number: C12N15/8218 ,  C07K14/415 ,  C12N15/8229 ,  C12N15/8261 ,  C12N15/8295 ,  Y02A40/146

Abstract: This disclosure provides a number of sequences involved in axillary bud growth in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences or transgenes of such sequences, and tobacco products made from tobacco leaf harvested from such plants.

Abstract translation: 本公开提供了涉及烟草腋芽生长的多个序列，使用这些序列的方法，携带这种序列的转基因的烟草植物，以及由此类序列的转基因制成的烟草制品以及从这些植物收获的烟叶制成的烟草制品。

公开(公告)号：US20250064011A1

公开(公告)日：2025-02-27

申请号：US18943128

申请日：2024-11-11

Applicant: Altria Client Services LLC

Inventor： Jesse Frederick ,  Yanxin Shen ,  Dongmei Xu ,  Ujwala Warek ,  James Arthur Strickland

IPC: A01H6/82 ,  A01H1/02 ,  A01H1/06 ,  A01H5/12 ,  A24B15/20 ,  C07K14/415 ,  C12N15/82 ,  C12Q1/6895 ,  G01N33/00

Abstract: This disclosure provides a number of sequences involved in the transport of alkaloids from the root to the leaf in tobacco, methods of using such sequences, tobacco plants carrying modifications to such sequences, and tobacco products made from such plants.

公开(公告)号：US11879130B2

公开(公告)日：2024-01-23

申请号：US17406829

申请日：2021-08-19

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Dongmei Xu ,  Jesse Frederick ,  Chengalrayan Kudithipudi ,  Yanxin Shen ,  James Strickland ,  Jaemo Yang

IPC: C12N15/82 ,  C07K14/415

CPC classification number: C12N15/8265 ,  C07K14/415 ,  C12N15/8213 ,  C12N15/8218 ,  C12N15/8225 ,  C12N15/8229 ,  C12N15/8261 ,  C12N15/8262 ,  C12N15/8294 ,  C12N2310/20

Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.

公开(公告)号：US11104912B2

公开(公告)日：2021-08-31

申请号：US16124941

申请日：2018-09-07

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Dongmei Xu ,  Jesse Frederick ,  Chengalrayan Kudithipudi ,  Yanxin Shen ,  James Strickland ,  Jaemo Yang

IPC: C12N15/82 ,  C07K14/415

Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.

公开(公告)号：US10457953B2

公开(公告)日：2019-10-29

申请号：US15486841

申请日：2017-04-13

Applicant: Altria Client Services LLC

Inventor： Yanxin Shen ,  Dongmei Xu

IPC: C12N15/82 ,  A01H1/06 ,  A01H5/12 ,  A24B13/00 ,  C07K14/415 ,  C12N9/02

Abstract: This disclosure provides tobacco plants that exhibit altered photosynthesis as well as methods of making and using such plants.

公开(公告)号：US12286637B2

公开(公告)日：2025-04-29

申请号：US18537046

申请日：2023-12-12

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Dongmei Xu ,  Jesse Frederick ,  Chengalrayan Kudithipudi ,  Yanxin Shen ,  James Strickland ,  Jaemo Yang

IPC: C12N15/82 ,  C07K14/415

Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.

公开(公告)号：US20250129379A1

公开(公告)日：2025-04-24

申请号：US18985344

申请日：2024-12-18

Applicant: Altria Client Services LLC

Inventor： Dongmei Xu ,  Chengalrayan Kudithipudi ,  Yanxin Shen ,  Jaemo Yang ,  Jesse Frederick ,  James Strickland

IPC: C12N15/82 ,  A24B13/00 ,  A24B15/10 ,  C07K14/415

Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.

公开(公告)号：US12209249B2

公开(公告)日：2025-01-28

申请号：US18476495

申请日：2023-09-28

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Dongmei Xu ,  Chengalrayan Kudithipudi ,  Yanxin Shen ,  Jaemo Yang ,  Jesse Frederick ,  James Strickland

IPC: C12N15/82 ,  A24B13/00 ,  A24B15/10 ,  C07K14/415

Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.