公开(公告)号：US20210260302A1

公开(公告)日：2021-08-26

申请号：US17261648

申请日：2019-08-16

Applicant: AMGEN INC.

Inventor： Matias Melander ,  Joshua Jay Dudman ,  Joseph Michael Iglesias ,  Bjarke Lykke Ludvig Svendsen ,  Adam B. McCullough ,  Christian Plambech ,  Steve Sanchez

IPC: A61M5/315 ,  A61M5/32 ,  A61M5/20

Abstract: A drug delivery device includes a housing, an injection assembly at least partially disposed in the housing, a shield, and a drive assembly at least partially disposed in the housing and coupled with the injection assembly and the shield. The shield has an extended position where at least a proximal end thereof extends a distance beyond a proximal end of the housing. The injection assembly includes a needle or cannula having an endpoint. Upon moving the shield axially towards the distal end of the housing a predetermined distance, a retraction profile commences whereby the drive assembly administers a medicament via the injection assembly. A peak resistance force is exerted within approximately the first 12 mm of axial movement of the shield.

公开(公告)号：US20210093789A1

公开(公告)日：2021-04-01

申请号：US17036556

申请日：2020-09-29

Applicant: AMGEN INC.

Inventor： Christian Plambech ,  Matias Melander ,  Bjarke Lykke Ludvig Svendsen ,  Joshua Jay Dudman ,  Michael Sorensen ,  Margaux Frances Boyaval ,  Avon Kuo

IPC: A61M5/315 ,  A61M5/20

Abstract: Drug delivery devices and related arrangements are disclosed. A drug delivery device may include a housing having an opening, a drug storage container including a delivery member with an insertion end configured to extend at least partially through the opening, and a plunger. A drive mechanism may be included for driving the plunger in a distal direction to expel a drug from the drug storage container through the delivery member upon activation. The drug delivery device may additionally include a guard moveably disposed adjacent to the opening and operably coupled to the drive mechanism for activation of the drive mechanism. A lock may be selectively engageable with the guard to limit movement of the guard in the proximal direction. An indicator may be coupled to the drive mechanism to generate an audible signal during drug delivery, and to cease generating the audible signal when drug delivery is complete.

公开(公告)号：US20190083359A1

公开(公告)日：2019-03-21

申请号：US16072767

申请日：2017-02-06

Applicant: AMGEN INC.

Inventor： Hans Stenberg Knudsen ,  Matias Melander ,  Jakob Halkjaer Pedersen

IPC: A61J1/20 ,  A61M39/10

Abstract: The present invention relates to a pharmaceutical adaptor system. The pharmaceutical adaptor system comprises a syringe assembly having an axial extension and comprising a first end part and a second end part, the first end part having a male tubular projection, the syringe assembly comprising a syringe and a connecting element having a first mechanical connection part, a unit such as a needle, a vial, a catheter or an IV line, and an adaptor providing fluid communication between the syringe and the unit and having a second mechanical connection part configured to engage with the first mechanical connection part in an engagement direction, thereby in fully engaged position preventing further relative axial movement between the adaptor and the male tubular projection, wherein the adaptor comprises a sealing element configured to receive the male tubular projection and provide sealing between the male tubular projection and the adaptor. The present invention also relates to a pharmaceutical kit system comprising a pharmaceutical adaptor system according to the present invention.