Unitized electrode with three-dimensional multi-site, multi-modal capabilities for detection and control of brain state changes

    公开(公告)号:US07006859B1

    公开(公告)日:2006-02-28

    申请号:US10622238

    申请日:2003-07-18

    IPC分类号: A61B5/042 A61N1/05

    摘要: An electrode with three-dimensional capabilities for detection and control of brain state changes of a subject. The electrode includes a disk portion having an upper surface and a lower surface, and a shaft portion secured to and extending perpendicularly outwardly from the lower surface of the disk portion; the shaft portion having an outer surface. The disk portion and shaft portion may include one or more recording or stimulating contact surfaces structured to operatively interact with the brain of a subject. Insulating material isolates each of the recording or stimulating contact surfaces from each other. At least one conductor operatively and separately connect each of the recording or stimulating contact surfaces in communication with external apparatus. The disk portion and shaft portion are structured relative to each other to operatively provide support and anchoring for each other while providing three-dimensional capabilities for detection and control of brain state changes of a subject. Modified embodiments include insertible/retractable electrode wires, both contained in channels and sheathed in axially displaceable cannulae; activating mechanisms for inserting/retracting the electrode wires and/or cannulae; and multiple shaft portions.

    Stimulation methodologies and apparatus for control of brain states
    22.
    发明授权
    Stimulation methodologies and apparatus for control of brain states 有权
    刺激方法和控制脑状态的装置

    公开(公告)号:US07551956B2

    公开(公告)日:2009-06-23

    申请号:US11151386

    申请日:2005-06-13

    IPC分类号: A61B5/04 A61N1/00

    摘要: A system for accessing the brain of a subject to record and/or stimulate brain stares thereof. The system includes control means, first accessing means having a plurality of contact surfaces configured to operatively connect the control means to the brain of the subject to provide three-dimensional stimulation thereof; second accessing means having a plurality of contact surfaces to operatively connect the control means to the brain of the subject to provide access thereto for the purposes of obtaining three-dimensional recordings of the brain electrical activity of the subject; and a waveform bank containing a plurality of stimulating waveforms. The control means is configured to operatively apply a first at least one of the stimulating waveforms of the waveform bank to the brain of the subject through the first accessing means and to assess acceptability within defined limits, as determined by preset criteria, of the subject's response to the application of the at first least one of the stimulating waveforms.

    摘要翻译: 用于访问受试者脑部以记录和/或刺激其脑神经的系统。 该系统包括控制装置,第一存取装置具有多个接触表面,其被配置为将控制装置可操作地连接到受试者的脑部以提供其三维刺激; 第二存取装置具有多个接触表面,以将控制装置可操作地连接到受试者的大脑以提供对其的访问,以获得对象的脑电活动的三维记录; 以及包含多个刺激波形的波形组。 控制装置被配置为通过第一访问装置将波形组的第一至少一个刺激波形可操作地应用于受试者的大脑,并且通过预设的标准来确定受试者的反应所确定的限定范围内的可接受性 涉及至少一个刺激波形的应用。

    Stimulation methodologies and apparatus for control of brain states

    公开(公告)号:US08588898B1

    公开(公告)日:2013-11-19

    申请号:US12456296

    申请日:2009-06-15

    IPC分类号: A61B5/04

    摘要: A system for accessing the brain of a subject to record and/or stimulate brain stares thereof. The system includes control means, first accessing means having a plurality of contact surfaces configured to operatively connect the control means to the brain of the subject to provide three-dimensional stimulation thereof; second accessing means having a plurality of contact surfaces to operatively connect the control means to the brain of the subject to provide access thereto for the purposes of obtaining three-dimensional recordings of the brain electrical activity of the subject; and a waveform bank containing a plurality of stimulating waveforms. The control means is configured to operatively apply a first at least one of the stimulating waveforms of the waveform bank to the brain of the subject through the first accessing means and to assess acceptability within defined limits, as determined by preset criteria, of the subject's response to the application of the at first least one of the stimulating waveforms.

    PLATFORM FOR DETECTION OF TISSUE CONTENT AND/OR STRUCTURAL CHANGES WITH CLOSED-LOOP CONTROL IN MAMMALIAN ORGANISMS
    24.
    发明申请
    PLATFORM FOR DETECTION OF TISSUE CONTENT AND/OR STRUCTURAL CHANGES WITH CLOSED-LOOP CONTROL IN MAMMALIAN ORGANISMS 审中-公开
    用于检测MAMMALIAN有机体的闭环控制的组织内容和/或结构变化的平台

    公开(公告)号:US20080200802A1

    公开(公告)日:2008-08-21

    申请号:US11952924

    申请日:2007-12-07

    IPC分类号: A61B5/053 A61B5/055

    摘要: Aspects include methods and apparatuses for effecting change over time in one or more measured regions of a body using a plurality of data sets obtained by analysis of applied signals to said region and effecting a change in treatment protocol. The method may include transmitting and receiving one or more of electromagnetic wave signals, applied acoustic wave signals and electrical signals transmitted through or reflected off of a portion of the measured body region. Some aspects may include determining a change in tissue structure, or a change in tissue content.

    摘要翻译: 方面包括使用通过分析对所述区域的施加信号而获得的多个数据集并且实现治疗方案改变而在身体的一个或多个测量区域中随时间改变的方法和装置。 所述方法可以包括发射和接收一个或多个电磁波信号,施加的声波信号以及通过测量的身体区域的一部分透射或反射的电信号。 一些方面可以包括确定组织结构的变化或组织内容的变化。

    PLATFORM FOR DETECTION OF TISSUE STRUCTURE CHANGE
    25.
    发明申请
    PLATFORM FOR DETECTION OF TISSUE STRUCTURE CHANGE 审中-公开
    用于检测组织结构变化的平台

    公开(公告)号:US20100324415A1

    公开(公告)日:2010-12-23

    申请号:US12754490

    申请日:2010-04-05

    IPC分类号: A61B6/00

    摘要: Aspects include methods and apparatuses for determining change over time in one or more measured regions of a body using a plurality of data sets obtained by analysis of applied signals to said region. The method may include transmitting and receiving one or more of electromagnetic wave signals, applied acoustic wave signals and electrical signals transmitted through or reflected off of a portion of the measured body region.

    摘要翻译: 方面包括使用通过分析所施加的信号到所述区域获得的多个数据集来确定身体的一个或多个测量区域中随时间变化的方法和装置。 所述方法可以包括发射和接收一个或多个电磁波信号,施加的声波信号以及通过测量的身体区域的一部分透射或反射的电信号。