公开(公告)号：US11377665B2

公开(公告)日：2022-07-05

申请号：US16372833

申请日：2019-04-02

Applicant: Altria Client Services LLC

Inventor： Chengalrayan Kudithipudi ,  Dongmei Xu ,  James Strickland ,  Yanxin Shen

IPC: C12N15/82 ,  A24B15/10 ,  C12N9/88 ,  A24B13/00 ,  A24B15/24 ,  A24B15/20

Abstract: The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), increase phenylalanine, or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs. Also provided are methods and compositions for increasing the expression of chorismate mutase and other transcription factors involved in anthocyanin biosynthesis.

公开(公告)号：US11293030B2

公开(公告)日：2022-04-05

申请号：US16529365

申请日：2019-08-01

Applicant: Altria Client Services LLC

Inventor： Chengalrayan Kudithipudi ,  Jaemo Yang ,  Yanxin Shen ,  Dongmei Xu ,  Ujwala Warek ,  James Strickland ,  Jesse Frederick

IPC: C12N15/82

Abstract: The present disclosure provides the identification of promoters that are preferentially active in tobacco axillary buds. Also provided are tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing tobacco plants comprising reduced or no sucker growth.

公开(公告)号：US10731173B2

公开(公告)日：2020-08-04

申请号：US15457553

申请日：2017-03-13

Applicant: ALTRIA CLIENT SERVICES LLC

Inventor： Dongmei Xu ,  Chengalrayan Kudithipudi ,  Yanxin Shen ,  Jaemo Yang ,  Jesse Frederick ,  James Strickland

IPC: C12N15/82 ,  C07K14/415 ,  A24B13/00 ,  A24B15/10

Abstract: The present disclosure provides the identification of genes involved in sucker growth in tobacco. Also provided are promoters that are preferentially active in tobacco axillary buds. Also provided are modified tobacco plants comprising reduced or no sucker growth. Also provided are methods and compositions for producing modified tobacco plants comprising reduced or no sucker growth.