EVERTING HEART VALVE
    25.
    发明申请

    公开(公告)号:US20180104055A1

    公开(公告)日:2018-04-19

    申请号:US15842215

    申请日:2017-12-14

    Abstract: The present invention provides methods and apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion. The invention also includes methods for endovascularly replacing a patient's heart valve. In some embodiments, the method includes the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve, wrapping at least a portion of the replacement valve about the anchor, and expanding the anchor to a deployed, configuration.

    METHODS AND APPARATUS FOR ENDOVASCULARLY REPLACING A HEART VALVE
    26.
    发明申请
    METHODS AND APPARATUS FOR ENDOVASCULARLY REPLACING A HEART VALVE 审中-公开
    用于内膜替换心脏瓣膜的方法和装置

    公开(公告)号:US20170056172A1

    公开(公告)日:2017-03-02

    申请号:US15138863

    申请日:2016-04-26

    Abstract: The invention includes methods of and apparatus for endovascularly replacing a heart valve of a patient. One aspect of the invention provides a method including the steps of endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve in an unexpanded configuration; and applying an external non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to change the shape of the anchor, such as by applying proximally and/or distally directed force on the anchor using a releasable deployment tool to expand and contract the anchor or parts of the anchor. Another aspect of the invention provides an apparatus including a replacement valve; an anchor; and a deployment tool comprising a plurality of anchor actuation elements adapted to apply a non-hydraulically expanding or non-pneumatically expanding actuation force on the anchor to reshape the anchor.

    Abstract translation: 本发明包括用于血管内置换患者心脏瓣膜的方法和装置。 本发明的一个方面提供了一种方法,包括以未膨胀的构造将置换瓣膜和可扩张锚固体血管内输送到心脏瓣膜附近的步骤; 以及在所述锚上施加外部非液压膨胀或非气动扩张的致动力以改变所述锚的形状,例如通过使用可释放的展开工具向所述锚上施加近端和/或远端定向的力, 锚或锚的部分。 本发明的另一方面提供了一种包括置换阀的装置; 锚点 以及展开工具,其包括适于在锚上施加非液压膨胀或非气动膨胀的致动力的多个锚致动元件,以重构锚固件。

    Everting heart valve
    27.
    发明授权

    公开(公告)号:US11484405B2

    公开(公告)日:2022-11-01

    申请号:US15842215

    申请日:2017-12-14

    Abstract: The present invention provides apparatus for endovascularly replacing a patient's heart valve. The apparatus includes a replacement valve and an expandable anchor configured for endovascular delivery to a vicinity of the patient's heart valve. In some embodiments, the replacement valve is adapted to wrap about the anchor, for example, by everting during endovascular deployment. In some embodiments, the replacement valve is not connected to expandable portions of the anchor. In some embodiments, the anchor is configured for active foreshortening during endovascular deployment. In some embodiments, the anchor includes expandable lip and skirt regions for engaging the patient's heart valve during deployment. In some embodiments, the anchor comprises a braid fabricated from a single strand of wire. In some embodiments, the apparatus includes a lock configured to maintain anchor expansion.

    Replacement valve and anchor
    28.
    发明授权

    公开(公告)号:US10925724B2

    公开(公告)日:2021-02-23

    申请号:US15842306

    申请日:2017-12-14

    Abstract: Apparatus for endovascularly replacing a patient's heart valve, including: a replacement valve adapted to be delivered endovascularly to a vicinity of the heart valve; an expandable anchor adapted to be delivered endovascularly to the vicinity of the heart valve; and a lock mechanism configured to maintain a minimum amount of anchor expansion. The invention also includes a method for endovascularly replacing a patient's heart valve. In some embodiments the method includes the steps of: endovascularly delivering a replacement valve and an expandable anchor to a vicinity of the heart valve; expanding the anchor to a deployed configuration; and locking the anchor in the deployed configuration.

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