公开(公告)号：US20210296004A1

公开(公告)日：2021-09-23

申请号：US17149231

申请日：2021-01-14

Applicant: Brainlab AG

Inventor： Bálint Varkuti

IPC: G16H50/70 ,  G16H50/20 ,  G16H20/40 ,  G16H40/20 ,  G16H30/40 ,  G16H40/63

Abstract: A method is provided for supporting determination of medical procedure by created adapted population data. The adapted population is determined by a user entered degree of similarity of the patient and is used to describe an adapted probability that the anatomical structure can be treated. The method further utilizes at least analysis of the medical image data from the patient. The created adapted population data describes an adapted population based on the user entered similarity and generates adapted outcome atlas data describing an adapted probability that a specific anatomical structure can be treated successfully by the medical procedure. The adapted probability is determined based on the generated adapted population.

公开(公告)号：US11026626B2

公开(公告)日：2021-06-08

申请号：US15540110

申请日：2016-01-18

Applicant: Brainlab AG

Inventor： Bálint Varkuti

IPC: A61B5/00 ,  A61B5/055 ,  A61B6/03 ,  G01R33/48 ,  G01R33/563 ,  G06T7/00 ,  G06T7/11 ,  G06T7/73 ,  G06T7/90 ,  G06T7/33 ,  G16H50/50 ,  A61N1/05

Abstract: A method is provided for determining an orientation of nerve fibres relative to a non-physiological electric field. Patient medical image data is acquired, which describes a patient medical image of an anatomical body part of a patient's body. The anatomical body part includes nerve tissue comprising white matter nerve fibres. Diffusion image data is acquired, which describes a diffusion-enhanced image of the anatomical body part. Atlas data is acquired, which describes a spatial distribution of grey value-based tissue classes in a model body part representing a model of the anatomical body part. Based on the patient image data, the diffusion image data, and the atlas data, fibre orientation data is determined. The fibre orientation data describes an orientation of the white matter nerve fibres. Electric field orientation data is acquired, which describes an orientation of the non-physiological electric field. The non-physiological electric field is an electric field simulated around a simulated electrode virtually placed in a predetermined spatial relationship relative to the anatomical body part. Based on the fibre orientation data and the electric field orientation data, relative orientation data is determined. The relative orientation data describes a relative orientation between the orientation of the white matter nerve fibres and the orientation of the electric field.

公开(公告)号：US10517679B2

公开(公告)日：2019-12-31

申请号：US15431570

申请日：2017-02-13

Applicant: Brainlab AG

Inventor： Bálint Varkuti

IPC: A61B17/00 ,  A61B34/20 ,  A61M25/01 ,  A61B17/34 ,  A61N1/05 ,  G06F19/00 ,  A61B90/00 ,  A61M39/02

Abstract: The present disclosure sets forth a guiding tube for placing medical implants within body tissue. The guiding tube includes an elongated, dimensionally stable tubular body encompassing an inner channel adapted to receive a medical implant wherein the tubular body has at least one electromagnetic element, the element configured to exert an electromagnetic force on at least one magnetic element of the medical implant inserted into the inner channel of the guiding tube. The medical implant includes a stimulation lead having at least one directional electrode with an elongated body insertable into an inner channel enclosed by a tubular body of the guiding tube.

公开(公告)号：US10463320B2

公开(公告)日：2019-11-05

申请号：US15537573

申请日：2015-12-18

Applicant: Brainlab AG

Inventor： Bálint Varkuti ,  Harald Braun

IPC: A61B6/00 ,  A61B6/04 ,  G16H40/63 ,  A61N5/10 ,  A61B6/03 ,  A61B6/12 ,  A61B90/11 ,  A61B90/14 ,  A61B10/02 ,  G06F19/00

Abstract: The present invention relates to positioning a patient's body part including a target relative to an imaging device that generates a radiation beam directed towards the target. Geometry data is received that describes the geometry of at least one structure located in the field of view of the imaging device. Tracking date is received that describes the spatial location and/or orientation of the at least one structure within the field of view of the imaging device. Position data is determined that incorporates the geometry date and the tracking data. The position data describes whether the location and/or orientation of the at least one structure with respect to an image trajectory is desirable. Repositioning data is determined that describes a desired location and/or orientation of the at least one structure with respect to the image trajectory. The repositioning data is output to allow repositioning of the at least one structure.

公开(公告)号：US20170312034A1

公开(公告)日：2017-11-02

申请号：US15431570

申请日：2017-02-13

Applicant: Brainlab AG

Inventor： Bálint Varkuti

IPC: A61B34/20 ,  A61B17/34 ,  G06F19/00 ,  A61N1/05

Abstract: The present invention relates to a guiding tube for placing medical implants within body tissue, comprising an elongated, dimensionally stable tubular body encompassing an inner channel adapted to receive a medical implant, wherein the tubular body comprises at least one electromagnetic element, which is configured to exert an electromagnetic force on at least one magnetic element of the medical implant inserted into the inner channel. The present invention further relates to a corresponding medical implant for being placed within body tissue, particularly a stimulation lead, specifically a deep brain stimulation lead comprising at least one directional electrode, having an elongated body portion that is adapted to be inserted into an inner channel enclosed by a tubular body of a guiding tube, wherein at least one magnetic element provided on or in the body portion. The present invention further relates to a corresponding stimulation lead placing system and a corresponding computer program for placing a medical implant.

公开(公告)号：US09741114B2

公开(公告)日：2017-08-22

申请号：US15034077

申请日：2013-11-05

Applicant: Brainlab AG

Inventor： Bálint Varkuti

IPC: G06K9/00 ,  G06T7/00 ,  G06T17/00 ,  A61B6/03 ,  A61B5/055 ,  A61B5/00 ,  A61B8/08 ,  G06F17/16 ,  A61B5/04 ,  G06F19/00 ,  A61B6/00

CPC classification number: G06T7/0012 ,  A61B5/055 ,  A61B5/4064 ,  A61B6/032 ,  A61B6/037 ,  A61B6/481 ,  A61B6/501 ,  A61B8/0808 ,  A61B8/488 ,  G06F17/16 ,  G06F19/00 ,  G06F19/321 ,  G06T17/005 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10092 ,  G06T2207/10104 ,  G06T2207/30016 ,  G06T2207/30241 ,  G06T2210/41 ,  G16H50/50

Abstract: The invention relates to a medical data processing method for determining a vulnerability field of a brain of a patient, the steps of the method being constituted to be executed by a computer and comprising: a) acquiring a nerve-indicating dataset comprising information about the brain of the patient suitable for identifying neural fibers in the brain of the patient; b) determining nodes within the brain preferably being neuron-rich grey matter parts of the brain; c) determining the axonal linkage of the nodes based on the nerve-indicating dataset to obtain edges connecting the nodes, the nodes and edges constituting a connectivity graph; d) determining a weight for each of the edges depending on centrality graph theoretical statistical measure of the respective edge in the connectivity graph; e) determining, for each of the edges, which voxels in a dataset of the brain of the patient belong to the edges or are passed by the edges and assigning or adding the determined weight of the respective edges to all of the voxels belonging to the respective edge to obtain a weighted voxel-based dataset of the brain of the patient defining the vulnerability field of the brain.

公开(公告)号：US20170091386A1

公开(公告)日：2017-03-30

申请号：US15311692

申请日：2014-09-05

Applicant: Brainlab AG

Inventor： Bálint Varkuti

IPC: G06F19/00

CPC classification number: G06F19/321 ,  G06F19/324 ,  G06F19/325 ,  G16H40/63 ,  G16H50/20 ,  G16H50/70

Abstract: A medical data processing method for supporting determination of medical image data describing a spatial distribution of body tissue which is the subject of a medical procedure, the method comprising the following steps which are constituted to be executed by a computer: a) acquiring outcome atlas data describing a general probability that a specific anatomical structure can be treated successfully by means of the medical procedure, the general probability having been determined based on a statistical analysis of medical image data and/or treatment effect simulations conducted on said medical image data generated from a general population of human bodies; b) acquiring general population data describing at least one statistical feature of each member of the general population; c) acquiring patient definition data describing at least one statistical feature of a patient who shall become the subject of the medical procedure; d) determining, based on the outcome atlas data and the general population data and the patient definition data, adapted population data describing an adapted population of human bodies taken from the general population, wherein the adapted population is to be used as a basis for generating adapted outcome atlas data describing an adapted probability that the specific anatomical structure can be treated successfully by means of the medical procedure, which adapted probability is determined based on the adapted population.