公开(公告)号：US10098633B2

公开(公告)日：2018-10-16

申请号：US15061037

申请日：2016-03-04

Applicant: Covidien LP

Inventor： Joshua B. Stopek ,  Matthew D. Cohen

IPC: A61B17/04 ,  A61B17/06 ,  A61L17/00 ,  A61B17/00

Abstract: Barbed surgical sutures are prepared with a bioactive agent thereon. In embodiments, the bioactive agent may be an antimicrobial or clotting agent deposited within the angle formed by the barb and the suture body. Placement of the bioactive agent in the angle between the barb and suture body enhances the delivery of the bioactive agent to wound tissue at the point of contact.

公开(公告)号：US20140228858A1

公开(公告)日：2014-08-14

申请号：US14175151

申请日：2014-02-07

Applicant: Covidien LP

Inventor： Joshua B. Stopek

IPC: A61B19/00 ,  A61N5/10

CPC classification number: A61N5/1039 ,  A61B34/10 ,  A61B90/37 ,  A61N5/1049 ,  A61N5/1068 ,  A61N2005/1051 ,  A61N2005/1055 ,  A61N2005/1058

Abstract: Systems and methods for treating a lung disease including capturing a first set of images of at least a portion of a lung displaying symptoms of a lung disease, generating a three dimensional model from the first set of images, locating a target nerve proximate the portion of the lung, generating a treatment plan, and on-invasively denervating the target nerve based on the treatment plan such that the function of the portion of the lung is affected.

Abstract translation: 用于治疗肺部疾病的系统和方法，包括捕获显示肺部疾病症状的肺的至少一部分的第一组图像，从第一组图像生成三维模型，将目标神经定位在邻近部分 肺，产生治疗计划，并且基于治疗计划对入侵神经进行去侵袭，使得部分肺部的功能受到影响。

公开(公告)号：US20140228614A1

公开(公告)日：2014-08-14

申请号：US14175135

申请日：2014-02-07

Applicant: Covidien LP

Inventor： Joshua B. Stopek

IPC: A61N5/10

CPC classification number: A61N5/1039 ,  A61B34/10 ,  A61B90/37 ,  A61N5/1049 ,  A61N5/1068 ,  A61N2005/1051 ,  A61N2005/1055 ,  A61N2005/1058

Abstract: Systems and methods for treating a lung disease including capturing a first set of images of at least a portion of a lung displaying symptoms of a lung disease, generating a three dimensional model from the first set of images, locating a target nerve proximate the portion of the lung, generating a treatment plan, and on-invasively denervating the target nerve based on the treatment plan such that the function of the portion of the lung is affected.

Abstract translation: 用于治疗肺部疾病的系统和方法，包括捕获显示肺部疾病症状的肺的至少一部分的第一组图像，从第一组图像生成三维模型，将目标神经定位在邻近部分 肺，产生治疗计划，并且基于治疗计划对入侵神经进行去侵袭，使得部分肺部的功能受到影响。

公开(公告)号：US08679157B2

公开(公告)日：2014-03-25

申请号：US13690614

申请日：2012-11-30

Applicant: Covidien LP

Inventor： Joshua B. Stopek ,  Matthew D. Cohen ,  Ahmad Robert Hadba ,  Gerald Hodgkinson

IPC: A61B17/04

CPC classification number: A61L17/005 ,  A61B17/06166 ,  A61B2017/00336 ,  A61B2017/00867 ,  A61B2017/00871 ,  A61B2017/00889 ,  A61B2017/00893 ,  A61B2017/06057 ,  A61B2017/06176 ,  A61L17/06 ,  A61L2300/404 ,  A61L2300/41 ,  A61L2300/412 ,  A61L2300/416 ,  A61L2300/602 ,  A61L2400/16

Abstract: Barbed surgical sutures are provided which include an elongated body and a plurality of barbs extending therefrom. A bioactive agent is disposed within barb angles formed between the barbs and the elongated body. The barbs may be made from a shape memory polymer having a permanent shape which may be deformed to a temporary shape, such that barbs of the suture extend at different barb angles in the different shape configurations. The barb angles of the permanent shape may be greater than the barb angles of the temporary shape, thereby exposing and/or releasing a bioactive agent after placement in tissue.

Abstract translation: 提供了带刺的外科缝合线，其包括细长主体和从其延伸的多个倒钩。 生物活性剂设置在倒钩和细长体之间形成的倒钩角内。 倒钩可以由具有永久形状的形状记忆聚合物制成，其可以变形为临时形状，使得缝线的倒钩在不同形状构造中以不同的倒钩角度延伸。 永久形状的倒刺角可以大于临时形状的倒钩角，从而在放置在组织中之后暴露和/或释放生物活性剂。