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公开(公告)号：US20240050344A1
公开(公告)日：2024-02-15
申请号：US18549085
申请日：2021-03-11
Applicant: Colgate-Palmolive Company
Inventor： Ying YANG , Shaopeng XU , Guofeng XU , Harsh Mahendra TRIVEDI , James MASTERS , Dandan CHEN , Betty WON
CPC classification number: A61K8/44 , A61K8/27 , A61Q11/00 , A61K8/21 , A61K2800/92
Abstract: Methods of increasing sIgA levels in an individual's oral cavity are disclosed. The methods comprise applying effective amounts of zinc oxide, zinc citrate, and arginine Methods of increasing the concentration of sIgA in the individual's mucosa pellicle in the oral cavity are disclosed. Methods of increasing phagocytotic activity of phagocytotic cells in the individual's oral cavity are also disclosed. In addition, methods of increasing levels of β-Defensin 1 in the individual's oral cavity are disclosed.
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公开(公告)号：US20230235468A1
公开(公告)日：2023-07-27
申请号：US18183275
申请日：2023-03-14
Applicant: Colgate-Palmolive Company
Inventor： Chun HUANG , Paloma PIMENTA , Guofeng XU , Matthew Lee KOLB
IPC: C25B15/023 , A61C19/06 , C25B15/02 , C01B11/06 , C25B9/17
CPC classification number: C25B15/023 , A61C19/066 , C01B11/06 , C25B9/17 , C25B15/02
Abstract: An electrolysis device may include a housing having a cavity that is configured to receive a precursor solution. The precursor solution may include chloride. An electrolysis circuit may be located in the cavity of the housing. The electrolysis circuit may include a power source, a first electrode and a second electrode electrically coupled to the power source, and a control circuit electrically coupled to the power source and the first and second electrodes. Upon the control circuit being activated while the precursor liquid operably couples the first and second electrodes together, the electrolysis circuit may be configured to generate a hypochlorite solution from the precursor solution.
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公开(公告)号：US20220323331A1
公开(公告)日：2022-10-13
申请号：US17723178
申请日：2022-04-18
Applicant: Colgate-Palmolive Company
Inventor： Shyamala PILLAI , Guofeng XU , LaTonya KILPATRICK-LIVERMAN , Xiang CHEN , Suman CHOPRA , Robert DICOSIMO , Mark PAYNE , Mahmoud HASSAN
IPC: A61K8/66 , A61Q11/00 , A61K8/22 , A61K8/81 , A61K8/06 , A61C19/06 , A61K8/37 , A61K8/44 , A61K8/31 , A61K8/49
Abstract: An oral care composition including a hydrophobic phase and a hydrophilic phase is disclosed. The hydrophobic phase may include a source of hydrogen peroxide and an acyl donor, and the hydrophilic phase may include an enzyme having perhydrolytic activity that catalyzes the generation of peracetic acid between the source of hydrogen peroxide and the acyl donor.
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公开(公告)号：US20210346271A1
公开(公告)日：2021-11-11
申请号：US17383540
申请日：2021-07-23
Applicant: Colgate-Palmolive Company
Inventor： Rong DONG , Guofeng XU
Abstract: A tooth whitening composition includes a hydrophobic copolymer, a hydrophilic whitening agent and a polar solvent.
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公开(公告)号：US20210308032A1
公开(公告)日：2021-10-07
申请号：US17345467
申请日：2021-06-11
Applicant: Colgate-Palmolive Company
Inventor： Shaotang YUAN , Guofeng XU , Jennifer GRONLUND , Robert DICOSIMO , Sharon HAYNIE , Mark PAYNE
Abstract: An oral care composition including an enzyme and an anhydrous matrix that at least partially stabilizes the enzyme. The anhydrous matrix includes a source of hydrogen peroxide, an acyl donor, a non-aqueous anhydrous liquid, and a thickener.
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Patent Agency Ranking
公开(公告)号：US20210196588A1
公开(公告)日：2021-07-01
申请号：US17247618
申请日：2020-12-18
Applicant: Colgate-Palmolive Company
Inventor： Paul Thomson , Robert D'AMBROGIO , Jean DENIS , Guofeng XU
Abstract: The invention relates to oral care compositions comprising a first stannous ion source, a second stannous ion source, wherein the second stannous ion comprises stannous pyrophosphate, and a source of zinc selected from zinc oxide, zinc citrate, zinc lactate, and combinations thereof, and a humectant system comprising glycerin and sorbitol, and a thickening system, as well as to methods of using and making these compositions.
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公开(公告)号：US20210000709A1
公开(公告)日：2021-01-07
申请号：US16840857
申请日：2020-04-06
Applicant: Colgate-Palmolive Company
Inventor： Shaoyi ZHANG , Saide TANG , Carl MYERS , Guofeng XU
Abstract: This application relates to novel aqueous oral care compositions useful for combining and delivering incompatible stannous fluoride or stannous chloride and potassium salts in a high-water composition, for example, to provide effective caries prevention, protection against dental erosion, and relief from dental hypersensitivity. The compositions comprise stannous fluoride or stannous chloride, nitric acid or a water-soluble nitrate salt, a water-soluble alkali metal polyphosphate and more than 10% water, by weight of the composition.
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公开(公告)号：US20200046629A1
公开(公告)日：2020-02-13
申请号：US16535693
申请日：2019-08-08
Applicant: Colgate-Palmolive Company
Inventor： Chun HUANG , Guofeng XU
Abstract: A whitening composition, an oral care product including the whitening composition, and a method for whitening teeth are disclosed. The whitening composition may include an anhydrous component and an aqueous component. The anhydrous component may include a base gel and a chloroisocyanurate. The chloroisocyanurate may be present in the anhydrous component in an amount of from about 0.01 weight % to about 30 weight %, based on a totally weight of the anhydrous component. The anhydrous component may include water.
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公开(公告)号：US20210000732A1
公开(公告)日：2021-01-07
申请号：US17023576
申请日：2020-09-17
Applicant: Colgate-Palmolive Company
Inventor： Rong DONG , Guofeng XU
Abstract: A tooth whitening composition includes a hydrophobic copolymer, a hydrophilic whitening agent and a polar solvent.
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公开(公告)号：US20200330342A1
公开(公告)日：2020-10-22
申请号：US16820909
申请日：2020-03-17
Applicant: Colgate-Palmolive Company
Inventor： Zhigang HAO , Paul THOMSON , Long PAN , Tatiana BRINZARI , Guofeng XU , Sergio LEITE , Yu WANG
Abstract: Disclosed herein are improved methods for the synthesis of stannous pyrophosphate, as well as improved methods for the manufacture of oral care compositions comprising stannous pyrophosphate.
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