-
公开(公告)号:US07785347B2
公开(公告)日:2010-08-31
申请号:US10540991
申请日:2003-12-30
申请人: Fraser Harvie , Graham Smith , Philip B. Sample , Gary R. McCarthy , Adam James , Peter Richardson , Sally L. Carter
发明人: Fraser Harvie , Graham Smith , Philip B. Sample , Gary R. McCarthy , Adam James , Peter Richardson , Sally L. Carter
IPC分类号: A61B17/04
CPC分类号: A61B17/3472 , A61B17/00491 , A61B17/0401 , A61B17/0467 , A61B17/0487 , A61B17/0642 , A61B17/0644 , A61B17/068 , A61B17/1615 , A61B17/1622 , A61B17/1637 , A61B17/1684 , A61B17/686 , A61B17/8819 , A61B17/8836 , A61B17/8869 , A61B2017/005 , A61B2017/0404 , A61B2017/0409 , A61B2017/0412 , A61B2017/0414 , A61B2017/0417 , A61B2017/0427 , A61B2017/0437 , A61B2017/0438 , A61B2017/044 , A61B2017/0446 , A61B2017/0458 , A61B2017/0462 , A61B2017/0647 , A61F2/0805 , A61F2002/0888 , A61F2210/0085
摘要: Surgical instruments and methods are provided. In one aspect, a method of securing a fixation device within an opening in a tissue is provided, including delivering a material in a flowable state to said opening, and changing the state of the material so that the material forms an interference fit that secures the fixation device in the opening.
摘要翻译: 提供手术器械和方法。 在一个方面,提供了一种将固定装置固定在组织内的开口内的方法,包括将材料以可流动状态传送到所述开口,并且改变材料的状态,使得材料形成干涉配合, 固定装置在开口。
-
公开(公告)号:US20060205641A1
公开(公告)日:2006-09-14
申请号:US10668846
申请日:2003-09-23
申请人: Graham Smith , Philip Hayes , Darren Smart , John Davis , Rosemary Kelsell
发明人: Graham Smith , Philip Hayes , Darren Smart , John Davis , Rosemary Kelsell
IPC分类号: A61K38/17 , C07K14/705 , C07H21/04 , C12P21/06
CPC分类号: C07K14/705
摘要: VANILREP4 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing VANILREP4 polypeptides and polynucleotides in diagnostic assays.
摘要翻译: VANILREP4多肽和多核苷酸以及通过重组技术产生此类多肽的方法。 还公开了在诊断测定中利用VANILREP4多肽和多核苷酸的方法。
-
公开(公告)号:US6068604A
公开(公告)日:2000-05-30
申请号:US58070
申请日:1998-04-09
申请人: Kenneth W. Krause , Graham Smith
发明人: Kenneth W. Krause , Graham Smith
CPC分类号: G01N3/405 , A61B5/0053 , A61B5/4514 , G01N2203/0089 , G01N2203/0208
摘要: An instrument and technique for measuring the compressive properties of a body (e.g., articular cartilage) are disclosed. The instrument includes an elongated probe, a biasing assembly for applying a pre-determined pre-load to the body to establish a measurement reference at the predetermined pre-load, an actuator to move the elongated probe to apply a compressive force to the body, and a measurement device which measures displacement of the elongated probe relative to the measurement reference.
摘要翻译: 公开了用于测量身体(例如关节软骨)的压缩特性的仪器和技术。 所述仪器包括细长的探针,用于将预定的预加载施加到所述身体以在所述预定的预载荷处建立测量基准的偏置组件,用于移动所述细长探针以对所述身体施加压缩力的致动器, 以及测量装置,其测量细长探针相对于测量基准的位移。
-
公开(公告)号:US5871493A
公开(公告)日:1999-02-16
申请号:US630537
申请日:1996-04-10
CPC分类号: A61B17/32002 , A61B17/162 , B25F3/00 , H01H36/00 , A61B2017/00367 , A61B2017/0046 , A61B2017/00477 , A61B2090/0813 , H01H2300/014 , H01H9/06
摘要: A surgical apparatus includes a body configured for insertion into a bore of a surgical handpiece and a latch that includes a resilient member connected to the body. The resilient member has a latching structure configured to latchingly engage a surface of the surgical handpiece within the bore.
-
公开(公告)号:US5749885A
公开(公告)日:1998-05-12
申请号:US538298
申请日:1995-10-02
申请人: Douglas D. Sjostrom , Michael A. Fritschy , Peter M. Cesarini , Alexander Grinberg , William G. McGee , Graham Smith
发明人: Douglas D. Sjostrom , Michael A. Fritschy , Peter M. Cesarini , Alexander Grinberg , William G. McGee , Graham Smith
CPC分类号: A61B17/32002 , A61B2017/00482
摘要: A surgical instrument includes a plastic hub which is received by a handpiece for operating the instrument. The plastic hub includes a wall that encloses a passage that receives a surgical tool-carrying member, and at least one detectable coding element is embedded at a selected circumferential position in the wall. For example, the coding element is embedded in a hole disposed in the wall. Alternatively, the coding element is molded into the wall during injection molding of the hub. The coding element is, for example, a magnet.
摘要翻译: 手术器械包括由用于操作仪器的手持件接收的塑料毂。 塑料轮毂包括壁,该壁包围接收外科手术工具承载构件的通道,并且至少一个可检测编码元件嵌入在壁中选定的圆周位置。 例如,编码元件嵌入设置在壁中的孔中。 或者,在轮毂的注射成型期间,编码元件被模制到壁中。 编码元件例如是磁铁。
-
公开(公告)号:US5608934A
公开(公告)日:1997-03-11
申请号:US319970
申请日:1994-10-06
申请人: Paul A. Torrie , Graham Smith
发明人: Paul A. Torrie , Graham Smith
CPC分类号: A61G13/12 , A61G13/0036 , A61G13/0081 , A61G13/1245
摘要: An apparatus and method for positioning a leg during surgery has a support for holding a substantial portion of one of the patient's legs on the side facing the other leg and a pivot located in the proximity of the patient's pelvis. After patient's pelvis is secured relative to the operating table, the distal end of the support can be moved for adjustment of the outer extremity of the patient's leg relative to the operating table to selectively position the leg relative to the patient's pelvis.
摘要翻译: 用于在手术期间定位腿的装置和方法具有支撑件,用于将患者腿部中的一个的大部分保持在面向另一腿部的一侧和位于患者骨盆附近的枢轴。 在病人的骨盆相对于手术台固定之后,可以移动支撑件的远端以相对于手术台调节患者腿部的外端,以选择性地将腿部相对于患者的骨盆定位。
-
公开(公告)号:US09468449B2
公开(公告)日:2016-10-18
申请号:US13076766
申请日:2011-03-31
申请人: Graham Smith
发明人: Graham Smith
CPC分类号: A61B17/1714 , A61B17/1739 , A61B17/1778 , A61B2017/00407 , A61F2/08
摘要: An acromioclavicular joint guide for forming multiple drill tunnels spaced apart by a predetermined distance employs two drill guides in a pivoting arrangement allowing one drill guide to pivot around the axis of the other. The drill guides are each disposed in a respective sleeve of a pivot block for insertion toward the surgical member along nonintersecting axes defined by the sleeve. An elongated arm attaches to the pivot block at a proximate end and has a aimer point at a distal end, in which the arm may extend around the surgical member via an inverted portion or bend such that the aimer point is on the insertion axis of the primary drill guide. In this manner the aimer point locates an exit of the hole from the insertion point defined by the primary drill guide, and the pivotal drill guide defines a second tunnel at the predetermined distance.
摘要翻译: 用于形成间隔开预定距离的多个钻孔隧道的肩锁关节引导件采用两个钻孔引导器,该枢转布置允许一个钻子引导件围绕另一钻杆枢转。 钻子引导件各自设置在枢转块的相应套筒中,用于沿着由套筒限定的不间断轴线朝向外科手术构件插入。 细长臂在近端附接到枢转块,并且在远端具有瞄准器点,其中臂可以经由倒置部分或弯曲部围绕外科构件延伸,使得瞄准器点在所述插入轴线上 主钻指南。 以这种方式,瞄准器点将孔的出口从由主钻导向器限定的插入点定位,并且枢转钻子引导器以预定距离限定第二隧道。
-
公开(公告)号:US08961930B2
公开(公告)日:2015-02-24
申请号:US13062064
申请日:2009-09-04
IPC分类号: A61K49/00 , C07D403/12 , C07D403/14 , C07D405/14 , A61K51/00 , A61M36/14
CPC分类号: C07D403/12 , C07D403/14 , C07D405/14
摘要: Isatin 5-sulfonamide derivatives, pharmaceutical compositions comprising the derivatives, their use as molecular imaging agents, their use for the diagnosis or treatment of diseases or disorders associated with dysregulation of apoptosis, methods for synthesizing the derivatives, methods for the molecular imaging of caspase activity and apoptosis, and methods of assessing the therapeutic effect of a test substance on caspase activity are disclosed.
摘要翻译: 靛红5-磺酰胺衍生物,包含衍生物的药物组合物,其作为分子显像剂的用途,其用于诊断或治疗与凋亡失调相关的疾病或病症的用途,合成衍生物的方法,半胱天冬酶活性的分子成像方法 并且公开了细胞凋亡和评估测试物质对胱天蛋白酶活性的治疗效果的方法。
-
公开(公告)号:US08572110B2
公开(公告)日:2013-10-29
申请号:US12327976
申请日:2008-12-04
CPC分类号: G06F17/30448 , G06F17/3066
摘要: A textual search index is used to identify data objects that have numerical properties that satisfy search queries. As described herein, a search index contains search index entries, each of which specifies a reference string and a set of data object identifiers. When an original search query is received, the search query is transformed into a transformed search query such that numerical comparison query elements in the original search query are transformed into equivalent textual comparison query elements. The search index is then used to identify ones of the data objects that satisfy the transformed search query. A list of the identified data objects may then be provided in response to the original search query.
-
公开(公告)号:US20110270255A1
公开(公告)日:2011-11-03
申请号:US13098930
申请日:2011-05-02
申请人: Graham Smith
发明人: Graham Smith
CPC分类号: A61B17/1684 , A61B17/1778
摘要: The present invention provides a surgical instrument for guiding a drill into bone, the surgical instrument comprising; an elongate body comprising a shaft having a handle towards its proximal end and a head towards its distal end, wherein the head comprises a mouth and jaw assembly, and the shaft comprises a lumen aligned with the longitudinal axis of the shaft and extending from the proximal end of the surgical instrument to the mouth of the shaft, wherein the lumen is suitable for receipt and passage of a drill, and the jaw assembly comprises a pair of opposed reciprocating arms.
摘要翻译: 本发明提供了一种用于将钻子引导到骨头中的外科器械,所述手术器械包括: 细长主体,其包括具有朝向其近端的手柄的轴和朝向其远端的头部,其中所述头部包括口和钳口组件,并且所述头部包括与所述轴的纵向轴线对准并且从所述近端 所述外科器械的端部到达所述轴的口部,其中所述内腔适于接收和通过钻孔,并且所述钳口组件包括一对相对的往复臂。
-
-
-
-
-
-
-
-
-