公开(公告)号：US20060062730A1

公开(公告)日：2006-03-23

申请号：US11260714

申请日：2005-10-27

申请人： Eriko Takeoka ,  Ryuichi Takamoto ,  Toshio Yanaki

发明人： Eriko Takeoka ,  Ryuichi Takamoto ,  Toshio Yanaki

IPC分类号： A61K49/00

CPC分类号： A61K8/342 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q7/00 ,  A61Q9/00 ,  G01N33/5088

摘要： A method for measuring skin absorbability of a substance, which includes measuring the amount of the substance which is penetrated into hair follicles; and using the resultant data as an index representing the amount of the substance which is absorbed through skin pores, to thereby determine the amount of the substance absorbed through skin pores and a method for measuring skin absorbability of a substance, which includes bringing the substance into contact with a first surface of a thin film that mimics the skin surface layer, a second surface of the film being brought into contact with artificial sebum; and evaluating the sebum transferability of the substance by using the degree of transfer of the substance to the artificial sebum as an index, are disclosed. A kit for performing the measurement method of the present invention is also disclosed.

公开(公告)号：US06656486B2

公开(公告)日：2003-12-02

申请号：US09959309

申请日：2001-10-23

申请人： Katsuyuki Kaneko ,  Ryota Yamasaki ,  Toshihito Yabu ,  Isamu Kaneda ,  Toshio Yanaki ,  Yoshikazu Soyama

发明人： Katsuyuki Kaneko ,  Ryota Yamasaki ,  Toshihito Yabu ,  Isamu Kaneda ,  Toshio Yanaki ,  Yoshikazu Soyama

IPC分类号： A61K600

CPC分类号： A61Q3/02 ,  A61K8/35 ,  A61K8/39

摘要： The object of the present invention is to provide a film composition which is solidified in water of which a painted film is rapidly solidified and also has proper usabilities for use as a manicure. To accomplish the object a film composition of the present invention comprises water insoluble film materials, and a solvent which dissolves the water insoluble film materials and soluble with water, wherein the solvent contains specified alkylene glycol ethers and ketones, and characterized by that the film materials are precipitated from the mixture of the remaining solvent and penetrating water in a painted film of the composition when the painted film is dipped in water.

摘要翻译： 本发明的目的是提供一种在水中固化的薄膜组合物，其中涂膜快速固化，并且还具有用作修指甲的适当的可用性。 为了达到该目的，本发明的薄膜组合物包括水不溶性薄膜材料和溶解水不溶性薄膜材料并溶于水的溶剂，其中溶剂含有特定的亚烷基二醇醚和酮，其特征在于薄膜材料 当将涂漆膜浸入水中时，在组合物的漆膜中从剩余溶剂和渗透水的混合物中沉淀出来。

公开(公告)号：US6127431A

公开(公告)日：2000-10-03

申请号：US115744

申请日：1998-07-15

申请人： Kazuyuki Miyazawa ,  Toshio Yanaki

发明人： Kazuyuki Miyazawa ,  Toshio Yanaki

IPC分类号： G01N29/28 ,  A61B8/00 ,  C08B37/00 ,  G10K11/02 ,  B01J13/00 ,  C12P19/04

CPC分类号： G10K11/02 ,  C08B37/0024

摘要： There is provided a .beta.-1,3 glucan obtained by applying ultrasonic treatment in a mixed solution of an organic solvent containing at least dimethyl sulfoxide to remove the contaminant proteins and there is provided a coupling medium for a probe of an ultrasonograph comprised of a gel composed of a .beta.-1,3 glucan, as a main component, from which contaminant proteins have been removed as a coupling medium for a probe of an ultrasonograph superior in physical properties and safety.

摘要翻译： 提供了通过在含有至少二甲基亚砜的有机溶剂的混合溶液中进行超声波处理以除去污染物蛋白而获得的β-1,3葡聚糖，并且提供了由凝胶组成的超声波检查仪的探针的偶联介质 由作为主要组分的β-1,3葡聚糖组成，从物质特性和安全性优异的超声波检查仪的探针中除去杂质蛋白质。

公开(公告)号：US4505757A

公开(公告)日：1985-03-19

申请号：US460300

申请日：1983-01-24

申请人： Takemasa Kojima ,  Kengo Tabata ,  Toshio Yanaki ,  Mitsuaki Mitani

发明人： Takemasa Kojima ,  Kengo Tabata ,  Toshio Yanaki ,  Mitsuaki Mitani

IPC分类号： C08B37/00 ,  C13K13/00

CPC分类号： C08B37/0033 ,  C08B37/0024

摘要： The description describes a process for depolymerization of a polysaccharide having a rod-like helical structure, comprising a step for forcing a solution of the polysaccharide in a solvent (solvent A) through a capillary at a high shear rate, to produce a lower molecular weight degraded polysaccharide, which has the same repeating unit and the same helical structure, as those of the original polysaccharide.

摘要翻译： 该描述描述了具有棒状螺旋结构的多糖的解聚方法，其包括将多糖在溶剂（溶剂A）中的溶液以高剪切速率通过毛细管的步骤，以产生较低的分子量 降解多糖，其具有与原始多糖相同的重复单元和相同的螺旋结构。

公开(公告)号：US07799319B2

公开(公告)日：2010-09-21

申请号：US11260714

申请日：2005-10-27

申请人： Eriko Takeoka ,  Ryuichi Takamoto ,  Toshio Yanaki

发明人： Eriko Takeoka ,  Ryuichi Takamoto ,  Toshio Yanaki

IPC分类号： A61K8/00 ,  A61K8/18 ,  A61Q9/00 ,  A61Q5/00

CPC分类号： A61K8/342 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q7/00 ,  A61Q9/00 ,  G01N33/5088

摘要： A method for measuring skin absorbability of a substance, which includes measuring the amount of the substance which is penetrated into hair follicles; and using the resultant data as an index representing the amount of the substance which is absorbed through skin pores, to thereby determine the amount of the substance absorbed through skin pores and a method for measuring skin absorbability of a substance, which includes bringing the substance into contact with a first surface of a thin film that mimics the skin surface layer, a second surface of the film being brought into contact with artificial sebum; and evaluating the sebum transferability of the substance by using the degree of transfer of the substance to the artificial sebum as an index, are disclosed. A kit for performing the measurement method of the present invention is also disclosed.

摘要翻译： 用于测量物质的皮肤吸收性的方法，其包括测量渗入毛囊中的物质的量; 并使用所得数据作为表示通过皮肤孔吸收的物质的量的指标，从而确定通过皮肤孔吸收的物质的量和测量物质的皮肤吸收性的方法，其包括使物质进入 与模拟皮肤表面层的薄膜的第一表面接触，膜的第二表面与人造皮脂接触; 并且通过使用物质转移到人造皮脂的程度作为指标来评估物质的皮脂转移性。 还公开了用于执行本发明的测量方法的套件。

公开(公告)号：US20090047312A1

公开(公告)日：2009-02-19

申请号：US12082130

申请日：2008-04-09

申请人： Kazuyuki Miyazawa ,  Isamu Kaneda ,  Toshio Yanaki ,  Tadashi Nakamura ,  Masatoshi Ochiai ,  Tomoyuki Kawasoe

发明人： Kazuyuki Miyazawa ,  Isamu Kaneda ,  Toshio Yanaki ,  Tadashi Nakamura ,  Masatoshi Ochiai ,  Tomoyuki Kawasoe

IPC分类号： A61K8/02 ,  A61Q5/00

CPC分类号： A61K8/042 ,  A61K8/0212 ,  A61K8/44 ,  A61K8/65 ,  A61K8/676 ,  A61K8/73 ,  A61K8/733 ,  A61K8/8147 ,  A61K8/8152 ,  A61K8/8158 ,  A61K8/86 ,  A61K8/97 ,  A61K8/982 ,  A61K9/0014 ,  A61K47/36 ,  A61K47/42 ,  A61K2800/412 ,  A61Q5/06 ,  A61Q5/065 ,  A61Q19/00 ,  A61Q19/02 ,  C08L5/00 ,  C08L5/04 ,  C08L5/12 ,  C08L89/06 ,  C08L2666/02

摘要： The present invention provides a microgel having a mean particle size of 0.1-1,000 μm, the microgel being produced from a gel which is formed by use of a hydrophilic compound capable of forming a gel. An external composition containing the microgel provides an excellent sensation during use; i.e., the composition provides neither sticky sensation during use nor frictional sensation. Furthermore, even when a large amount of a pharmaceutical ingredient, such as a whitening ingredient, or a salt is incorporated into the composition, the viscosity of the composition is not lowered, and the composition exhibits excellent viscosity increasing property. In addition, the composition exhibits long-term stability, without inviting separation of water.

摘要翻译： 本发明提供了一种平均粒径为0.1-1000μm的微凝胶，该微凝胶由凝胶制成，其通过使用能形成凝胶的亲水性化合物形成。 含有微凝胶的外用组合物在使用过程中提供极好的感觉; 即，该组合物在使用期间既不提供粘性感，也不提供摩擦感。 此外，即使在组合物中加入大量的增白成分或者盐等药物成分，也不会降低组合物的粘度，而且显示出优异的增粘性。 此外，该组合物长期稳定，不会引起水分离。

公开(公告)号：US20060034762A1

公开(公告)日：2006-02-16

申请号：US11259882

申请日：2005-10-27

申请人： Eriko Takeoka ,  Ryuichi Takamoto ,  Toshio Yanaki

发明人： Eriko Takeoka ,  Ryuichi Takamoto ,  Toshio Yanaki

IPC分类号： A61K49/00 ,  C12Q1/00

CPC分类号： A61K8/342 ,  A61Q5/00 ,  A61Q5/02 ,  A61Q7/00 ,  A61Q9/00 ,  G01N33/5088

摘要： A method for measuring skin absorbability of a substance, which includes measuring the amount of the substance which is penetrated into hair follicles; and using the resultant data as an index representing the amount of the substance which is absorbed through skin pores, to thereby determine the amount of the substance absorbed through skin pores and a method for measuring skin absorbability of a substance, which includes bringing the substance into contact with a first surface of a thin film that mimics the skin surface layer, a second surface of the film being brought into contact with artificial sebum; and evaluating the sebum transferability of the substance by using the degree of transfer of the substance to the artificial sebum as an index, are disclosed. A kit for performing the measurement method of the present invention is also disclosed.

摘要翻译： 用于测量物质的皮肤吸收性的方法，其包括测量渗入毛囊中的物质的量; 并使用所得数据作为表示通过皮肤孔吸收的物质的量的指标，从而确定通过皮肤孔吸收的物质的量和测量物质的皮肤吸收性的方法，其包括使物质进入 与模拟皮肤表面层的薄膜的第一表面接触，膜的第二表面与人造皮脂接触; 并且通过使用物质转移到人造皮脂的程度作为指标来评估物质的皮脂转移性。 还公开了用于执行本发明的测量方法的套件。

公开(公告)号：US4965354A

公开(公告)日：1990-10-23

申请号：US161170

申请日：1988-02-26

申请人： Toshio Yanaki ,  Shigeki Maehata ,  Tomoko Satoh ,  Shinji Ikeda

发明人： Toshio Yanaki ,  Shigeki Maehata ,  Tomoko Satoh ,  Shinji Ikeda

IPC分类号： A23L1/308 ,  C08B37/00

CPC分类号： C08B37/0009 ,  A23L33/26 ,  C08B37/00 ,  Y10S426/804

摘要： A process for producing a condensed polysaccharide, which comprises heat-melting at least one compound selected from the group consisting of glucose, mannose, galactose, xylose and arabinose, which contains from 8 to 180 ppm of hydrogen chloride, followed by dehydration condensation under reduced pressure.

摘要翻译： 一种冷凝多糖的制备方法，其包括将至少一种选自葡萄糖，甘露糖，半乳糖，木糖和阿拉伯糖的化合物加热熔融，所述化合物含有8至180ppm的氯化氢，然后在还原下进行脱水缩合 压力。

公开(公告)号：US20110165323A1

公开(公告)日：2011-07-07

申请号：US12926497

申请日：2010-11-22

申请人： Takashi Oka ,  Nobuyoshi Koga ,  Emiko Takasu ,  Toshio Yanaki

发明人： Takashi Oka ,  Nobuyoshi Koga ,  Emiko Takasu ,  Toshio Yanaki

IPC分类号： B05D5/00 ,  B05D7/00 ,  B82Y99/00

CPC分类号： A61K8/11 ,  A61K2800/412 ,  A61Q1/12 ,  B01F3/1214 ,  B01F3/1221

摘要： A production method of dry water containing an aqueous ingredient coated with a hydrophobic powder to form a powder state capable of liquefying upon embrocation at the time of use, wherein the dry water is produced by charging a hydrophobic powder and an aqueous ingredient into a hollow container forming a hydrophobic enclosed space in the inside thereof, followed by agitating at a high speed in the enclosed hydrophobic hollow container to form the aqueous ingredient to fine aqueous droplets, and then allowing the surfaces of the fine aqueous droplets to be uniformly adsorbed with the hydrophobic powder, whereby the dry water in the form of a powder state, but is capable of being liquefied upon embrocation at the time of use to be simply produced in a large scale.

摘要翻译： 一种干燥水的制造方法，其含有涂覆有疏水性粉末的水性成分，以形成在使用时能够在通气时液化的粉末状态，其中所述干燥水是通过将疏水性粉末和水性成分装入中空容器 在其内部形成疏水封闭空间，随后在封闭的疏水性中空容器中高速搅拌，以形成水性成分以精细的水滴，然后使细小水滴的表面均匀地被疏水性吸附 粉末，由此形成粉末形式的干燥水，但是在使用时能够在刺穿时液化，以便大量简单地生产。

公开(公告)号：US07927615B2

公开(公告)日：2011-04-19

申请号：US12576438

申请日：2009-10-09

申请人： Isamu Kaneda ,  Toshio Yanaki

发明人： Isamu Kaneda ,  Toshio Yanaki

IPC分类号： A61K8/81 ,  A61K8/04 ,  A61Q1/00 ,  A61Q15/00 ,  A61Q5/00

CPC分类号： C08F2/32 ,  A61K8/042 ,  A61K8/8158 ,  A61Q1/02 ,  A61Q5/00 ,  A61Q5/065 ,  A61Q5/08 ,  A61Q15/00 ,  A61Q17/005 ,  A61Q19/00 ,  A61Q19/002 ,  A61Q19/04 ,  C09K3/00 ,  Y10S514/844

摘要： The present invention is a thickener consisting of a microgel obtained by radical polymerization of water soluble ethylene-type unsaturated monomers dissolved in the dispersion phase in a composition having an organic solvent or an oil component as the dispersion medium and water as the dispersion phase, as well as a cosmetic containing said thickener.Also, the present invention is a method of manufacturing a water-swelling polymer in a radical polymerization system consisting of a composition having an organic solvent or oil component as the dispersion medium and an aqueous solution of a water soluble ethylene type unsaturated monomer as the dispersion phase wherein said system contains a surfactant chosen in such a way that the aforementioned composition forms a single phase W/O microemulsion or fine W/O emulsion at a thermal radical polymerization temperature and said thermal radical polymerization is carried out at a temperature equal to or higher than the phase transition temperature of the radical polymerization system, yet not higher than the phase transition temperature by 20° C. or more.

摘要翻译： 本发明是一种增稠剂，其由通过溶解在分散相中的水溶性乙烯型不饱和单体在具有有机溶剂或作为分散介质的油成分的组合物中的自由基聚合而获得的增稠剂，作为分散相的水作为 以及含有所述增稠剂的化妆品。 此外，本发明是一种在由具有有机溶剂或油性成分作为分散介质的组合物和作为分散体的水溶性乙烯型不饱和单体的水溶液组成的自由基聚合体系中制造水溶性聚合物的方法 相，其中所述体系含有选择的表面活性剂，使得上述组合物在热自由基聚合温度下形成单相W / O微乳液或细W / O乳液，并且所述热自由基聚合在等于或等于 高于自由基聚合体系的相变温度，但不高于相转变温度20℃以上。