摘要:
Various examples of a drug delivery device and corresponding method for sequentially delivering at least two medicaments via a single dispense interface are provided. In one example, the device includes a variable dose setting mechanism operably connected to a first cartridge containing a first medicament, a fixed dose setting mechanism operably connected to a second cartridge containing a second medicament, a dose setter for setting a user settable dose of the first medicament and a fixed dose of the second medicament, and a connecting feature for detachably connecting the variable dose setting mechanism to the fixed dose setting mechanism. During setting of the fixed dose of the second medicament, the rotationally driven variable dose setting mechanism and the fixed dose setting mechanism are connected via the connecting feature, however, during setting of the user settable dose of the first medicament, the rotationally driven variable dose setting mechanism and the fixed dose setting mechanism are not connected.
摘要:
A computerized electro-mechanical drug delivery device configured to deliver at least one dose of two or more medicaments. The device comprises a control unit. An electro-mechanical drive unit is operably coupled to the control unit and a primary reservoir for a first medicament and a secondary reservoir for a fluid agent, e.g. a second medicament. An operator interface is in communication with the control unit. A single dispense assembly is configured for fluid communication with the primary and the secondary reservoir. Activation of the operator panel sets a first dose from the primary reservoir and based on the first dose and a therapeutic dose profile, the control unit is configured to determine a dose or range of the fluid agent. Alternatively, the control unit determines or calculates a dose or range of a third medicament. Further, a dispense interface for use with a drug delivery device is disclosed.
摘要:
A communication system includes a switching network and a wireless network. The switching network includes a first gateway for receiving a communication from a caller, a second gateway for establishing an external connection through which the communication can be routed, and a command center that allows the first and second gateways to make an internal connection. The wireless network includes a visited mobile switch center and a home location register. The visited mobile switch center generates routing information, receives the communication from the external connection of the switching network, and routes the communication to a wireless network subscriber. The home location register locates the visited mobile switch center, and passes the routing information from the visited mobile switch center to the command center of the switching network. The command center causes the external connection to be established based on the routing information.
摘要:
The present invention relates to a drug delivery (5) comprising a housing (10) with a proximal end (28) and a distal end (22), a cartridge holder (14) adapted to retain a cartridge, the cartridge holder (14) being secured to the housing (10) and having an at least partially transparent side wall, and a cap (40) being capable of covering the distal end (22) of the drug delivery device, being rotationally fixed with respect to the housing (10) and comprising a window aperture (44), the window aperture (44) being capable of displaying information revealed by the cartridge holder (14). Furthermore, using a cap (40) for covering the distal end (22) of the drug delivery device (5) is disclosed.
摘要:
A seat belt system for a vehicle may include a tongue configured to slidably engage a seat belt; a retractor coupled to a portion of the vehicle, the retractor configured to receive the seat belt; and a height adjuster. The height adjuster may include a guide webbing configured to be secured to a portion of the vehicle; a frame supporting a locking mechanism; and a supporting surface to support the seat belt as the seat belt changes direction. The position of the frame relative to the guide webbing is adjustable. The locking mechanism is configured to lock the frame in a position relative to the guide webbing by clamping the guide webbing without input from the user and stays in position during a crash.
摘要:
A continuous or batch process for the production and recovery of substantially pure carboxylic acids and ammonium salts from a corresponding nitrile. By controlling the amount of water used in the reaction, a biphasic reaction mixture forms which facilitate simultaneous recovery of both fractions. In a preferred embodiment, using propionitrile as the starting material and strong sulfuiric acid, propionic acid of approximately 98% purity is produced in the upper phase. A combination of hydrochloric and sulfuric acid can reduce the total reaction volume.
摘要:
An injection system for co-delivery of two medicaments (1, 2) having a drug delivery device (7) containing a primary reservoir (11) containing a first medicament (1) and having a secondary reservoir (5, 17, 30) containing a second medicament (2) where the drug delivery device (7) has only one dose setter (12) for the primary reservoir (11) and that automatically determines the dose of the second medicament (2). Both medicaments (1, 2) are delivered through a single dispense interface (3, 16, 21, 31).