公开(公告)号：US07961944B2

公开(公告)日：2011-06-14

申请号：US11933516

申请日：2007-11-01

申请人： Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang

发明人： Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang

IPC分类号： G06K9/34

CPC分类号： G06T17/10

摘要： A method for modeling a 2-dimensional tubular structure in a digitized image includes providing a digitized image of a tubular structure containing a plurality of 2D balls of differing radii, initializing a plurality of connected spline segments that form an envelope surrounding the plurality of 2D balls, each the spline segment Si being parameterized by positions of the ith and i+1th balls and contact angles αi, αi+1 from the center of each respective ball to a point on the perimeter of each the ball contacting the spline segment Si, each the αi affecting spline segment Si and Si−1, and updating the angles by minimizing an energy that is a functional of the angles, where the updating is repeated until the energy is minimized subject to a constraint that the envelope is tangent to each ball at each point of contact, where the envelope is represented by the contact angles.

摘要翻译： 一种用于对数字化图像中的二维管状结构进行建模的方法包括提供包含不同半径的多个2D球的管状结构的数字化图像，初始化形成围绕多个2D球的包围的多个连接的花键片段 每个花键片段Si由第i和第i + 1个球的位置参数化，接触角αi，αi+ 1从每个相应球的中心到接触花键片段Si的每个球的周边上的点，每个 αi影响样条段Si和Si-1，并且通过使作为角度的函数的能量最小化来更新角度，其中重复更新直到能量被最小化，受限于包围与每个球相切的约束 每个接触点，其中信封由接触角表示。

公开(公告)号：US20090016588A1

公开(公告)日：2009-01-15

申请号：US12150817

申请日：2008-05-01

申请人： Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang ,  Brian Whited ,  Jaroslaw Rossignac

发明人： Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang ,  Brian Whited ,  Jaroslaw Rossignac

IPC分类号： G06K9/34

CPC分类号： G06K9/342 ,  G06T7/11 ,  G06T2200/04 ,  G06T2207/10072 ,  G06T2207/20101 ,  G06T2207/30101

摘要： A method and system for segmenting tubular structures in 3D images is disclosed. User inputs identifying a first region on the image inside of a tubular structure and a second region of the image outside of the tubular structure are received. Based on this information, an ordered series of pearls are generated along the tubular structure. Pearls are spheres, each having a center location and a radius determined based on the center locations and radii of previous pearls and on local voxel intensities in the image. A continuous model of the tubular structure can be generated by interpolating the center locations and radii of the ordered series of pearls. The ordered series of pearls can be displayed and easily edited in response to user input, thus providing an efficient and flexible method for interactive segmentation of a potion of interest in a tubular structure.

摘要翻译： 公开了一种用于在3D图像中分割管状结构的方法和系统。 接收识别管状结构内部的图像上的第一区域和管状结构外部的图像的第二区域的用户输入。 基于该信息，沿管状结构产生有序的珍珠系列。 珍珠是球体，每个球体具有基于中心位置和先前珍珠的半径确定的中心位置和半径以及图像中的局部体素强度。 可以通过内插有序系列珍珠的中心位置和半径来生成管状结构的连续模型。 可以根据用户输入显示和容易地编辑有序的珍珠系列，从而为管状结构中感兴趣的药水进行交互式分割提供了一种有效和灵活的方法。

公开(公告)号：US08155405B2

公开(公告)日：2012-04-10

申请号：US12045327

申请日：2008-03-10

申请人： Gozde Unal ,  Gregory G. Slabaugh ,  Tong Fang ,  Shawn Lankton ,  Valer Canda ,  Stefan Thesen ,  Shuping Qing

发明人： Gozde Unal ,  Gregory G. Slabaugh ,  Tong Fang ,  Shawn Lankton ,  Valer Canda ,  Stefan Thesen ,  Shuping Qing

IPC分类号： G06K9/00 ,  G06K9/34

CPC分类号： G06K9/6207 ,  G06F19/00 ,  G06K9/342 ,  G06K2009/366 ,  G06K2209/053 ,  G06T7/12 ,  G06T7/149 ,  G06T7/194 ,  G06T2200/04 ,  G06T2207/10088 ,  G06T2207/20104 ,  G06T2207/30096

摘要： A method for lesion segmentation in 3-dimensional (3D) digital images, includes selecting a 2D region of interest (ROI) from a 3D image, the ROI containing a suspected lesion, extending borders of the ROI to 3D forming a volume of interest (VOI), where voxels on the borders of the VOI are initialized as background voxels and voxels in an interior of the VOI are initialized as foreground voxels, propagating a foreground and background voxel competition where for each voxel in the VOI, having each neighbor voxel in a neighborhood of the voxel attack the voxel, and, if the attack is successful, updating a label and strength of the voxel with that of the successful attacking voxel, and evolving a surface between the foreground and background voxels in 3D until an energy functional associated with the surface converges in value, where the surface segments the suspected lesion from the image.

摘要翻译： 一种用于三维（3D）数字图像中的病变分割的方法，包括从3D图像中选择感兴趣的2D区域（ROI），ROI包含疑似病变，将ROI的边界延伸到形成感兴趣体积的3D（ VOI），其中VOI边界上的体元被初始化为背景体元素，并且VOI内部的体素被初始化为前景体素，传播前景和背景体素竞争，其中对于VOI中的每个体素，具有每个相邻体素 体素的邻域攻击体素，并且如果攻击成功，更新体素的标签和强度与成功的攻击体素的标记和强度，并且以3D形式在前景和背景体素之间演变出一个表面，直到能量功能相关 其表面收敛于值，其中表面将图像中的可疑病变分割。

公开(公告)号：US07801343B2

公开(公告)日：2010-09-21

申请号：US11555806

申请日：2006-11-02

申请人： Gozde Unal ,  Yan Yang ,  Gregory G. Slabaugh ,  Tong Fang

发明人： Gozde Unal ,  Yan Yang ,  Gregory G. Slabaugh ,  Tong Fang

IPC分类号： G06K9/00 ,  A61B5/05

CPC分类号： A61B5/6852 ,  A61B5/0066 ,  A61B5/0086

摘要： A method and apparatus for automatically detecting stent struts in an image is disclosed whereby the inner boundary, or lumen, of an artery wall is first detected automatically and intensity profiles along rays in the image are determined. In one embodiment, detection of the lumen boundary may be accomplished, for example, by evolving a geometric shape, such as an ellipse, using a region-based algorithm technique, a geodesic boundary-based algorithm technique or a combination of the two techniques. Once the lumen boundary has been determined, in another embodiment, the stent struts are detected using a ray shooting algorithm whereby a ray is projected outward in the OCT image starting from the position in the image of the OCT sensor. The intensities of the pixels along the ray are used to detect the presence of a stent strut in the image.

摘要翻译： 公开了一种用于自动检测图像中的支架支柱的方法和装置，其中首先自动检测动脉壁的内边界或内腔，并确定与图像中的光线的强度分布。 在一个实施例中，可以例如通过使用基于区域的算法技术，基于测地边界的算法技术或两种技术的组合来演示诸如椭圆的几何形状来实现流明边界的检测。 一旦已经确定了管腔边界，在另一个实施例中，使用射线射击算法来检测支架支柱，由此射线从OCT传感器的图像中的位置开始向OCT中投射。 使用沿着光线的像素的强度来检测图像中支架支柱的存在。

公开(公告)号：US07720268B2

公开(公告)日：2010-05-18

申请号：US11427960

申请日：2006-06-30

申请人： Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang ,  Michael Wels

发明人： Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang ,  Michael Wels

IPC分类号： G06K9/00

CPC分类号： G06T5/002 ,  G06T5/003 ,  G06T5/10 ,  G06T5/20 ,  G06T7/12 ,  G06T7/143 ,  G06T7/149 ,  G06T2207/10132 ,  G06T2207/20032 ,  G06T2207/20056 ,  G06T2207/20064 ,  G06T2207/30096

摘要： A method for segmenting a digitized ultrasound image includes providing a digitized in-phase/quadrature ultrasound image comprising a plurality of intensities defined on an N-dimensional grid, decorrelating the ultrasound image wherein spatial correlations are substantially reduced in the intensity data, modeling the decorrelated image intensities with a statistical distribution, propagating, an active contour in the image where the contour segments the image, where the contour is propagated based on the statistical distributions of intensity data inside and outside the active contour.

摘要翻译： 用于分割数字化超声图像的方法包括提供数字化的同相/正交超声图像，其包括在N维网格上定义的多个强度，去相关超声图像，其中空间相关性在强度数据中显着降低，对去相关的 具有统计分布的图像强度，传播图像中的主动轮廓，其中轮廓分割图像，其中基于活动轮廓内部和外部的强度数据的统计分布传播轮廓。

公开(公告)号：US20100045671A1

公开(公告)日：2010-02-25

申请号：US12413913

申请日：2009-03-30

申请人： Gregory G. Slabaugh ,  Jaroslaw Rossignac ,  Brian Whited ,  Tong Fang ,  Gozde Unal

发明人： Gregory G. Slabaugh ,  Jaroslaw Rossignac ,  Brian Whited ,  Tong Fang ,  Gozde Unal

IPC分类号： G06T17/00

CPC分类号： G06T17/10

摘要： A method of computing a continuous interpolation of a discrete set of three-dimensional (3D) balls, including generating an initial skin, wherein the initial skin is a surface comprised of splines and wherein the splines touch each ball along a circle that is tangent to the ball, solving a first differential equation to minimize the initial skin's surface area or solving a second differential equation to minimize a squared mean curvature of the initial skin's surface, wherein the result of solving the first or second differential equations is an updated skin; and repeating the steps of solving the first or second differential equations for the updated skin, and then, repeating the steps of solving the first or second differential equations for each subsequently updated skin until a desired skin is realized.

摘要翻译： 一种计算三维（3D）球的离散组的连续插值的方法，包括生成初始皮肤，其中所述初始皮肤是由样条线组成的表面，并且其中所述花键沿着与所述三维 所述球解决第一微分方程以最小化初始皮肤的表面积或求解第二微分方程以最小化初始皮肤表面的平均平均曲率，其中求解第一或第二微分方程的结果是更新的皮肤; 并且重复解决用于更新的皮肤的第一或第二微分方程的步骤，然后重复以下步骤：为每个随后更新的皮肤求解第一或第二微分方程，直到实现期望的皮肤。

公开(公告)号：US08379957B2

公开(公告)日：2013-02-19

申请号：US11620078

申请日：2007-01-05

申请人： Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang ,  Huy-Nam Doan

发明人： Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang ,  Huy-Nam Doan

IPC分类号： G06K9/00 ,  G06K9/34

CPC分类号： G06K9/342 ,  G06K9/6224 ,  G06K2209/05

摘要： A system and method for segmentation of anatomical structures in MRI volumes using graph cuts is disclosed. In this method, a template is registered to an MRI brain volume. The template identifies seed points of anatomical brain structures, such as the cerebrum, the cerebellum, and the brain stem, in the MRI brain volume. Any or all of the anatomical brain structures can be segmented using graph cuts segmentation initialized based on the seed points identified by the template. It is possible to segment each of the anatomical brain structures by performing a hierarchical three-phase segmentation process including brain/non-brain segmentation, cerebrum/cerebellum and brain stem segmentation, and cerebellum/brain stem segmentation.

摘要翻译： 公开了一种用于使用图形切割来分割MRI体积中的解剖结构的系统和方法。 在该方法中，将模板登记到MRI脑体积。 该模板在MRI脑容量中识别解剖脑结构的种子点，如大脑，小脑和脑干。 可以使用基于由模板识别的种子点初始化的图切割分段来分割任何或所有解剖脑结构。 通过执行包括脑/非脑分割，大脑/小脑和脑干分割以及小脑/脑干分割的分层三阶段分割过程，可以分割每个解剖脑结构。

公开(公告)号：US07787678B2

公开(公告)日：2010-08-31

申请号：US11538921

申请日：2006-10-05

申请人： Gozde Unal ,  Gregory G. Slabaugh ,  Tong Fang

发明人： Gozde Unal ,  Gregory G. Slabaugh ,  Tong Fang

IPC分类号： G06K9/00 ,  G06F7/60

CPC分类号： G06T7/0012 ,  G06T7/12 ,  G06T7/149 ,  G06T2207/10088 ,  G06T2207/20101 ,  G06T2207/20116 ,  G06T2207/30004

摘要： Certain exemplary embodiments can comprise a method, which can comprise, automatically determining a target object from an image via an application of an iterative minimization algorithm to an energy function. Each iteration of the iterative minimization algorithm can comprise a comparison of a model with an estimated contour of the target object.

摘要翻译： 某些示例性实施例可以包括一种方法，其可以包括通过将迭代最小化算法应用于能量函数从图像自动确定目标对象。 迭代最小化算法的每次迭代可以包括模型与目标对象的估计轮廓的比较。

公开(公告)号：US07711148B2

公开(公告)日：2010-05-04

申请号：US11566363

申请日：2006-12-04

申请人： Gregory G. Slabaugh ,  Koon Yin Kong ,  Gozde Unal ,  Tong Fang

发明人： Gregory G. Slabaugh ,  Koon Yin Kong ,  Gozde Unal ,  Tong Fang

IPC分类号： G06K9/00 ,  H05G1/64

CPC分类号： G06K9/6207 ,  G06T7/0012 ,  G06T7/149 ,  G06T7/246 ,  G06T2207/10121 ,  G06T2207/30021

摘要： A method of tracking a guidewire in video imagery includes: obtaining a first video image including pixels associated with features of a guidewire; selecting a set of parameters to define an open curve on the first video image; determining a feature map of the first video image using phase congruency; and updating the parameters of the open curve using the feature map to align the open curve to the pixels associated with the features of the guidewire.

摘要翻译： 在视频图像中跟踪导丝的方法包括：获得包括与导丝的特征相关联的像素的第一视频图像; 选择一组参数以在第一视频图像上定义开放曲线; 使用相位一致性确定第一视频图像的特征图; 并使用特征图更新开放曲线的参数，以将开放曲线对准与导丝的特征相关联的像素。

公开(公告)号：US07623127B2

公开(公告)日：2009-11-24

申请号：US11466211

申请日：2006-08-22

申请人： Hui Xie ,  Jin Zhou ,  Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang

发明人： Hui Xie ,  Jin Zhou ,  Gregory G. Slabaugh ,  Gozde Unal ,  Tong Fang

IPC分类号： G06T15/00 ,  G06T17/00 ,  G09G5/00

CPC分类号： G06T17/20

摘要： A method and apparatus for rounding a sharp edge of a model of an object is disclosed whereby a ball is propagated in a desired direction along the edge to be smoothed. The position of the ball at each point in its propagation is noted and, as a result, a virtual tunnel through which the ball passed may be constructed. Points on the sides of the surface of the object in proximity to the sharp edge are then projected onto the virtual tunnel by connecting with a line each point in proximity to the sharp edge to the center of the tunnel. New projected points are created at each position on the surface of the tunnel where the lines intersect that surface. The original points along the sharp edge are then hidden or deleted and the points along the virtual tunnel are connected via well-known surface reconstruction methods. In this way, a sharp edge of a triangle mesh model are advantageously smoothed.

摘要翻译： 公开了一种用于使物体的模型的锋利边缘倒圆的方法和装置，其中球沿着待平滑的边缘在期望的方向上传播。 注意到球在其传播中的每个点处的位置，结果可以构造球通过的虚拟隧道。 接近尖锐边缘的物体表面侧面的点然后通过与尖锐边缘附近的每条线连接到隧道中心而投射到虚拟隧道上。 在隧道表面的每个位置上创建新的投影点，其中线与该表面相交。 然后沿尖锐边缘的原始点被隐藏或删除，沿着虚拟隧道的点通过公知的表面重建方法连接。 以这种方式，有利地平滑了三角形网格模型的尖锐边缘。