-
公开(公告)号：US07871990B1
公开(公告)日：2011-01-18
申请号：US12456927
申请日：2009-06-24
申请人： Hsing-Wen Sung , Hsiang-Fa Liang , Hosheng Tu
发明人： Hsing-Wen Sung , Hsiang-Fa Liang , Hosheng Tu
CPC分类号： A61K9/5146 , A61K9/0043 , A61K9/19 , A61K9/4891 , A61K9/5161 , A61K31/13 , A61K31/445 , A61K31/55 , A61K47/61
摘要： The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one protein drug or bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular protein drug and bioactive agent delivery.
-
公开(公告)号：US20060073210A1
公开(公告)日：2006-04-06
申请号：US11029082
申请日：2005-01-04
申请人： Hsing-Wen Sung , Hsiang-Fa Liang , Hosheng Tu
发明人： Hsing-Wen Sung , Hsiang-Fa Liang , Hosheng Tu
IPC分类号： A61K9/50
CPC分类号： A61K9/5146 , A61K9/0019 , A61K9/5161 , A61K31/13 , A61K31/473 , A61K31/55 , A61K31/7008 , A61K31/704 , A61K31/727 , A61K33/24 , A61K38/28 , A61K45/06 , A61K2300/00
摘要： The invention discloses the nanoparticles composed of chitosan/poly-γ-glutamic acid characterized with a positive surface charge and their enhanced permeability through Caco-2 cells for paracellular drug delivery.
摘要翻译： 本发明公开了由壳聚糖/聚-γ-谷氨酸组成的纳米颗粒，其特征在于具有阳性表面电荷并且通过Caco-2细胞提高细胞外药物递送的通透性。
-
公开(公告)号：US20060073209A1
公开(公告)日：2006-04-06
申请号：US10958864
申请日：2004-10-05
申请人： Hsing-Wen Sung , Hsiang-Fa Liang , Ting-Fan Yang , Chin-Tsung Huang , Hosheng Tu
发明人： Hsing-Wen Sung , Hsiang-Fa Liang , Ting-Fan Yang , Chin-Tsung Huang , Hosheng Tu
IPC分类号： A61K31/704 , A61K31/7008 , A61K33/24 , A61K9/50
CPC分类号： A61K9/5153 , A61K31/7008 , A61K31/704 , A61K33/24 , A61K45/06 , A61K2300/00
摘要： The invention discloses the nanoparticles composed of γ-PGA-PLA block copolymers conjugated with galactosamine as a potential drug delivery system for treating liver cancers.
摘要翻译： 本发明公开了由与半乳糖结合的γ-PGA-PLA嵌段共聚物作为用于治疗肝癌的潜在药物递送系统的纳米颗粒。
-
公开(公告)号：US07879361B2
公开(公告)日：2011-02-01
申请号：US11442192
申请日：2006-05-26
申请人： Hsing-Wen Sung , Yu-Hsin Lin , Mei-Chin Chen , Hosheng Tu
发明人： Hsing-Wen Sung , Yu-Hsin Lin , Mei-Chin Chen , Hosheng Tu
CPC分类号： A61K31/22 , A61K9/5146 , A61K9/5161 , A61K31/366 , A61K31/401 , A61K31/722 , A61K31/727 , A61K47/36 , A61K47/6931 , A61K47/6939 , B82Y5/00
摘要： The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one bioactive agent of HMG-CoA reductase inhibitors or erythropoietin. The nanoparticles are characterized with a positive surface charge and their enhanced permeability for paracellular drug delivery.
摘要翻译： 本发明公开了由壳聚糖，聚谷氨酸和HMG-CoA还原酶抑制剂或促红细胞生成素的至少一种生物活性剂组成的纳米颗粒。 纳米颗粒的特征在于具有阳性表面电荷并且其增加细胞旁药物递送的渗透性。
-
公开(公告)号：US07381716B2
公开(公告)日：2008-06-03
申请号：US11398145
申请日：2006-04-05
申请人： Hsing-Wen Sung , Yu-Hsin Lin , Hosheng Tu
发明人： Hsing-Wen Sung , Yu-Hsin Lin , Hosheng Tu
IPC分类号： A01N43/04
CPC分类号： A61K9/5146 , A61K9/0019 , A61K9/5161 , A61K31/13 , A61K31/445 , A61K31/55 , A61K47/61
摘要： The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular drug delivery.
-
公开(公告)号：US07291598B2
公开(公告)日：2007-11-06
申请号：US11398440
申请日：2006-04-05
申请人： Hsing-Wen Sung , Yu-Hsin Lin , Hosheng Tu
发明人： Hsing-Wen Sung , Yu-Hsin Lin , Hosheng Tu
CPC分类号： A61K9/5146 , A61K9/5161 , A61K47/36 , A61K47/6931 , A61K47/6939 , B82Y5/00
摘要： The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular drug delivery.
摘要翻译： 本发明公开了由壳聚糖，聚谷氨酸和至少一种生物活性剂组成的纳米颗粒，其特征在于具有阳性表面电荷和增强细胞旁药物递送的渗透性。
-
公开(公告)号：US20070116771A1
公开(公告)日：2007-05-24
申请号：US11398145
申请日：2006-04-05
申请人： Hsing-Wen Sung , Yu-Hsin Lin , Hosheng Tu
发明人： Hsing-Wen Sung , Yu-Hsin Lin , Hosheng Tu
IPC分类号： A61K31/55 , A61K31/445 , A61K31/13 , A61K9/14
CPC分类号： A61K9/5146 , A61K9/0019 , A61K9/5161 , A61K31/13 , A61K31/445 , A61K31/55 , A61K47/61
摘要： The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular drug delivery.
-
公开(公告)号：US20090011008A1
公开(公告)日：2009-01-08
申请号：US12221897
申请日：2008-08-07
申请人： Hsing-Wen Sung , Yu-Hsin Lin , Hosheng Tu
发明人： Hsing-Wen Sung , Yu-Hsin Lin , Hosheng Tu
CPC分类号： A61K9/5161 , A61K9/19 , A61K9/5169 , A61K38/28
摘要： The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one protein drug or bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular protein drug and bioactive agent delivery.
-
公开(公告)号：US20070237831A1
公开(公告)日：2007-10-11
申请号：US11433008
申请日：2006-05-12
申请人： Hsing-Wen Sung , Yu-Hsin Lin , Mei-Chin Chen , Hosheng Tu
发明人： Hsing-Wen Sung , Yu-Hsin Lin , Mei-Chin Chen , Hosheng Tu
IPC分类号： A61K39/395 , A61K9/50
CPC分类号： A61K47/36 , A61K9/5146 , A61K9/5161 , A61K47/61 , A61K47/6925 , B82Y5/00 , Y10S977/733 , Y10S977/915
摘要： The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one bioactive agent of monoclonal antibody. The nanoparticles are characterized with a positive surface charge and their enhanced permeability for paracellular drug delivery.
摘要翻译： 本发明公开了由壳聚糖，聚谷氨酸和至少一种单克隆抗体生物活性剂组成的纳米颗粒。 纳米颗粒的特征在于具有阳性表面电荷并且其增加细胞旁药物递送的渗透性。
-
公开(公告)号：US20070116772A1
公开(公告)日：2007-05-24
申请号：US11398440
申请日：2006-04-05
申请人： Hsing-Wen Sung , Yu-Hsin Lin , Hosheng Tu
发明人： Hsing-Wen Sung , Yu-Hsin Lin , Hosheng Tu
CPC分类号： A61K9/5146 , A61K9/5161 , A61K47/36 , A61K47/6931 , A61K47/6939 , B82Y5/00
摘要： The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one bioactive agent characterized with a positive surface charge and their enhanced permeability for paracellular drug delivery.
-
-
-
-
-
-
-
-
-
搜索结果
359 条记录 (耗时 0.029 秒)
