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公开(公告)号:US08778849B2
公开(公告)日:2014-07-15
申请号:US13661524
申请日:2012-10-26
Applicant: Illumina, Inc.
Inventor: M. Shane Bowen , Kevin L. Gunderson , Shengrong Lin , Maria Candelaria Rogert Bacigalupo , Kandaswamy Vijayan , Yir-Shyuan Wu , Bala Murali Venkatesan , James Tsay , John M. Beierle , Lorenzo Berti , Sang Ryul Park
CPC classification number: C12Q1/6844 , B01J19/0046 , B01J2219/00529 , B01J2219/00608 , B01J2219/00621 , B01J2219/00637 , B01J2219/00641 , B01J2219/00644 , B01J2219/00648 , B01J2219/00653 , B01J2219/00659 , B01J2219/00662 , B01J2219/00722 , B01J2219/00788 , C12Q1/686 , C40B50/18 , C12Q2527/125 , C12Q2535/122 , C12Q2565/543
Abstract: A microarray is designed capture one or more molecules of interest at each of a plurality of sites on a substrate. The sites comprise base pads, such as polymer base pads, that promote the attachment of the molecules at the sites. The microarray may be made by one or more patterning techniques to create a layout of base pads in a desired pattern. Further, the microarrays may include features to encourage clonality at the sites.
Abstract translation: 设计的微阵列在基底上的多个位点的每一个处捕获一个或多个感兴趣的分子。 这些部位包括促进分子在部位附着的基底垫,例如聚合物基底垫。 微阵列可以通过一种或多种图案化技术制成,以产生所需图案中的基底布局。 此外,微阵列可以包括在站点鼓励克隆性的特征。