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    CARTRIDGE HOLD-UP VOLUME REDUCTION
    21.
    发明申请
    CARTRIDGE HOLD-UP VOLUME REDUCTION 审中-公开

    公开(公告)号：US20200179608A1

    公开(公告)日：2020-06-11

    申请号：US16794689

    申请日：2020-02-19

    Applicant: Insulet Corporation

    Inventor： Maureen MCCAFFREY ,  David NAZZARO ,  Ian MCLAUGHLIN ,  Simon KOZIN

    IPC: A61M5/28 ,  A61M5/24 ,  A61M5/34 ,  A61M5/32 ,  A61M5/315 ,  A61M5/142

    Abstract: Drug delivery systems with reduced hold-up volumes are provided. The drug delivery systems include a cartridge configured to hold a liquid drug. A cartridge stopper is positioned in a first portion of the cartridge. A needle guide component is positioned within the cartridge stopper. A needle is positioned within a central opening of the needle guide. A plunger is positioned in a second portion of the cartridge. The plunger includes a fluid path pocket facing and aligned with the central opening of the needle guide component. The plunger is driven toward the cartridge stopper to expel the liquid drug from the cartridge through the needle. An end of the needle can be positioned within the fluid path pocket when the plunger is pushed against the cartridge stopper, ensuring that only a small volume of the liquid drug remains in the cartridge when delivery of the liquid drug is completed.

    DRUG DELIVERY SHUTTLE PUMP SYSTEM AND VALVE ASSEMBLY
    22.
    发明申请
    DRUG DELIVERY SHUTTLE PUMP SYSTEM AND VALVE ASSEMBLY 审中-公开

    公开(公告)号：US20200164143A1

    公开(公告)日：2020-05-28

    申请号：US16697920

    申请日：2019-11-27

    Applicant: Insulet Corporation

    Inventor： Steven CARDINALI ,  Lucas MCGAHREN ,  Nicholas LAU ,  Ian MCLAUGHLIN

    IPC: A61M5/168 ,  A61M5/142

    Abstract: A multiple pulse volume shuttle pump powered by a shape memory alloy (SMA) wire is disclosed. In some embodiments, a shuttle pump system may include a pump chamber, a valve operable with the pump chamber, and a wire coupled to a valve shaft of the valve for controlling a position of the valve. The shuttle pump system may further include a pin disposed within an inset pathway of a cam, wherein the pin is moveable between multiple positions of the inset pathway in response to actuation of the valve shaft.

    FLUID FLOW REGULATION ARRANGEMENTS FOR DRUG DELIVERY DEVICES
    23.
    发明申请
    FLUID FLOW REGULATION ARRANGEMENTS FOR DRUG DELIVERY DEVICES 审中-公开

    公开(公告)号：US20190038835A1

    公开(公告)日：2019-02-07

    申请号：US16049388

    申请日：2018-07-30

    Applicant: Insulet Corporation

    Inventor： David NAZZARO ,  Ian MCLAUGHLIN ,  Daniel ALLIS ,  Jason O'CONNOR

    IPC: A61M5/168 ,  A61M5/28 ,  A61M5/32 ,  A61M5/315

    Abstract: A fluid flow regulator of a fluid delivery system that can adjust a flow rate of a liquid drug dispensed from a liquid drug container to a user is provided. The fluid flow regulator can be coupled to an end of the liquid drug container. The fluid flow regulator can include a compliance plate and a flow channel selector plate having a fluid flow channel. The flow channel selector plate can be rotated relative to the compliance plate and the liquid drug container to expose a selected portion of the fluid flow channel to openings in the compliance plate that are in fluid communication with the liquid drug stored in the liquid drug container. The selected portion of the fluid flow channel can correspond to a corresponding flow resistance of the liquid drug through the fluid flow channel, thereby regulating the flow of the liquid drug to the user.

    FLUID DELIVERY DEVICE HAVING MULTIPLE PENETRATING ELEMENTS
    28.
    发明申请
    FLUID DELIVERY DEVICE HAVING MULTIPLE PENETRATING ELEMENTS 有权

    公开(公告)号：US20220105267A1

    公开(公告)日：2022-04-07

    申请号：US17492103

    申请日：2021-10-01

    Applicant: Insulet Corporation

    Inventor： Steven CARDINALI ,  David NAZZARO ,  Ian MCLAUGHLIN

    IPC: A61M5/158 ,  A61M5/172

    Abstract: Methods and apparatuses for performing an insertion process for a plurality of penetrating elements are described. For example, a wearable fluid infusion device may include a cannula and/or needle for infusing a fluid into a patient and a sensor for sensing a physical characteristic of the patient. A non-limiting example of a fluid may be or may include insulin. An illustrative and non-restrictive example of a physical characteristic may include a blood glucose level. The wearable infusion device may be configured to facilitate insertion of the multiple penetrating elements, such as a cannula and a sensor, in a single simultaneous insertion step instead of requiring individual insertion steps for each of multiple penetrating elements. Other embodiments are described.

    SYSTEMS AND METHODS FOR ACTIVATING DRUG DELIVERY DEVICES
    29.
    发明申请
    SYSTEMS AND METHODS FOR ACTIVATING DRUG DELIVERY DEVICES 有权

    公开(公告)号：US20220062550A1

    公开(公告)日：2022-03-03

    申请号：US17412684

    申请日：2021-08-26

    Applicant: Insulet Corporation

    Inventor： David NAZZARO ,  Jason O'CONNOR ,  Ian MCLAUGHLIN ,  Joon Bok LEE ,  Thomas METZMAKER ,  Bret CHRISTENSEN ,  Philip HILLDALE

    IPC: A61M5/172 ,  A61M5/142

    Abstract: Embodiments of the present disclosure relate to approaches for transitioning a drug delivery device from a low-energy sleep state to a high-energy active state. In some embodiments, a system may include a drug delivery device, the drug delivery device including a pump mechanism coupled to a reservoir for expelling a liquid drug from the reservoir; and an activation component communicatively coupled to the pump mechanism. The activation component may include at least one of a sensor and a mechanical activation device, and a wake-up circuit operable to receive an input from the sensor or the mechanical activation device, wherein the input indicates a change in a device characteristic. Based on the change in the device characteristic, the wake-up circuit may be further operable to transition the drug delivery device from a low-energy state to an active state.

    SINGLE DOSE DRUG DELIVERY DEVICE
    30.
    发明申请
    SINGLE DOSE DRUG DELIVERY DEVICE 有权

    公开(公告)号：US20210379293A1

    公开(公告)日：2021-12-09

    申请号：US17408523

    申请日：2021-08-23

    Applicant: Insulet Corporation

    Inventor： David NAZZARO ,  Ian MCLAUGHLIN ,  Simon KOZIN ,  Maureen MCCAFFREY ,  Jackie MAC ,  Alexander DOUDOUMOPOULOS ,  Bhavin PATEL

    IPC: A61M5/315 ,  A61M5/142 ,  A61M5/28 ,  A61M5/32

    Abstract: A wearable drug delivery device that can deliver a liquid drug stored in a container to a patient is provided. The container can be a prefilled cartridge that can be loaded into the drug delivery device by the patient or that can be preloaded within the drug delivery device when provided to the patient. A sealed end of the container is pierced to couple the stored liquid drug to a needle conduit that is coupled to a needle insertion component that provides access to the patient. A drive system of the drug delivery device can expel the liquid drug from the cartridge to the patient through the needle conduit. The drive system can be controlled to provide the liquid drug to the patient in a single dose or over multiple doses.

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