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公开(公告)号：US20210379293A1
公开(公告)日：2021-12-09
申请号：US17408523
申请日：2021-08-23
Applicant: Insulet Corporation
Inventor： David NAZZARO , Ian MCLAUGHLIN , Simon KOZIN , Maureen MCCAFFREY , Jackie MAC , Alexander DOUDOUMOPOULOS , Bhavin PATEL
Abstract: A wearable drug delivery device that can deliver a liquid drug stored in a container to a patient is provided. The container can be a prefilled cartridge that can be loaded into the drug delivery device by the patient or that can be preloaded within the drug delivery device when provided to the patient. A sealed end of the container is pierced to couple the stored liquid drug to a needle conduit that is coupled to a needle insertion component that provides access to the patient. A drive system of the drug delivery device can expel the liquid drug from the cartridge to the patient through the needle conduit. The drive system can be controlled to provide the liquid drug to the patient in a single dose or over multiple doses.
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公开(公告)号：US20210100959A1
公开(公告)日：2021-04-08
申请号：US17125150
申请日：2020-12-17
Applicant: Insulet Corporation
Inventor： Maureen MCCAFFREY , Ian MCLAUGHLIN
Abstract: A needle mechanism module for automatically inserting a fluid path into a patient for drug delivery is provided. The needle mechanism module can be a component of a wearable drug delivery device. The needle mechanism module can insert a needle and cannula into the patient responsive to activation of the drug delivery device by a user. After insertion, the needle can be automatically retracted, leaving only the cannula in the patient. As a result, discomfort of the user is reduced.
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公开(公告)号：US20180126068A1
公开(公告)日：2018-05-10
申请号：US15809491
申请日：2017-11-10
Applicant: Insulet Corporation
Inventor： David NAZZARO , Simon KOZIN , Maureen MCCAFFREY
CPC classification number: A61M5/1452 , A61M5/14248 , A61M5/16804 , A61M5/16877 , A61M5/31536 , A61M5/31546 , A61M5/31568 , A61M2005/14533 , A61M2005/3154
Abstract: Ratchet-based drive systems for more reliable and safer drug delivery are provided. The ratchet-based drive systems restrict angular movement and/or linear movement of components that cause a plunger to expel a liquid drug from a drug container. Movement of the components can be restricted to correspond to a predetermined or desired portion of the liquid drug. In the case that control of the drive system is lost or fails, the maximum amount of drug that could be delivered is limited to a known amount, thereby reducing the likelihood of an overdose.
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公开(公告)号：US20230211077A1
公开(公告)日：2023-07-06
申请号：US18149996
申请日：2023-01-04
Applicant: INSULET CORPORATION
Inventor： Maureen MCCAFFREY , Daniel ALLIS
Abstract: Disclosed herein are various embodiments providing an expandable, flexible reservoir for use in a wearable drug delivery device. The reservoir comprises a flexible enclosure made with plastic film which incorporates pleats forming the side walls thereof to increase the volume efficiency and to avoid a “pillowing” effect when the reservoir is filled. The pleats may be formed at non-right angles with respect to each other such as to form a curved side walls for the reservoir. In variations of the invention, various methods are disclosed for maintaining a vacuum with the reservoir during its shelf life.
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公开(公告)号：US20210016015A1
公开(公告)日：2021-01-21
申请号：US17039570
申请日：2020-09-30
Applicant: Insulet Corporation
Inventor： Steven CARDINALI , David NAZZARO , Daniel ALLIS , Maureen MCCAFFREY
IPC: A61M5/315
Abstract: Drive systems for a drug delivery device are provided. The drive systems can be positioned within a container that stores a liquid drug to be delivered to a user. The drive systems can be coupled to a plunger positioned within the container. The drive systems can be incrementally advanced to drive the plunger further into the container, thereby expelling a portion of the stored liquid drug from the container for delivery to the user. The container can be any type of container including a pre-filled, standardized drug cartridge. The drive systems and container can be components of a wearable drug delivery device.
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Patent Agency Ranking
公开(公告)号：US20190091417A1
公开(公告)日：2019-03-28
申请号：US16140178
申请日：2018-09-24
Applicant: INSULET CORPORATION
Inventor： Maureen MCCAFFREY , Ian MCLAUGHLIN
Abstract: A needle mechanism module for automatically inserting a fluid path into a patient for drug delivery is provided. The needle mechanism module can be a component of a wearable drug delivery device. The needle mechanism module can insert a needle and cannula into the patient responsive to activation of the drug delivery device by a user. After insertion, the needle can be automatically retracted, leaving only the cannula in the patient. As a result, discomfort of the user is reduced.
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公开(公告)号：US20240042126A1
公开(公告)日：2024-02-08
申请号：US18160429
申请日：2023-01-27
Applicant: INSULET CORPORATION
Inventor： Soroush KAMRAVA , Kyle BREINGAN , Maureen MCCAFFREY , Jeffrey BARNES
IPC: A61M5/142
CPC classification number: A61M5/142 , A61M2005/14252
Abstract: Disclosed herein is a double reservoir configuration for a pumping mechanism for a drug delivery device wherein one reservoir is rigidly fixed to a housing of the device and the other reservoir moves linearly translates with respect to the fixed reservoir. To avoid having either the input fluid port or the output fluid port moves as the second reservoir linearly translates, one port is in fluid communication with the fixed reservoir and a second fluid port is in communication with the moving reservoir via a hollow tube supporting a static plunger disposed within the moving reservoir. This arrangement provides for the added benefit of allowing air trapped within either of the reservoirs to be almost completely removed as the pump mechanism is filled with the fluid.
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公开(公告)号：US20230063696A1
公开(公告)日：2023-03-02
申请号：US18045739
申请日：2022-10-11
Applicant: INSULET CORPORATION
Inventor： David NAZZARO , Ian MCLAUGHLIN , Daniel ALLIS , Simon KOZIN , Maureen MCCAFFREY
Abstract: Systems and methods for monitoring an operational state and/or a fill status of a drug container of a drug delivery device are provided. The drug container can hold a liquid drug. A plunger can be positioned within the drug container. A drive system can advance the plunger to expel the liquid drug from the container. A monitoring system can detect a movement and/or a position of the plunger and/or any component coupled to the plunger. The detection can enable determination of an amount of liquid drug that has been expelled and/or an amount of liquid drug remaining in the drug container. Dosing rates, flow rates, and dosage completion can also be determined.
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公开(公告)号：US20220062542A1
公开(公告)日：2022-03-03
申请号：US17412666
申请日：2021-08-26
Applicant: Insulet Corporation
Inventor： David NAZZARO , Jason O'CONNOR , Ian MCLAUGHLIN , Philip HILLDALE , Joon Bok LEE , Bret CHRISTENSEN , Maureen MCCAFFREY , Thomas METZMAKER
Abstract: Embodiments of the present disclosure relate to techniques, processes, devices or systems for automating fluid delivery without the use of an external interface device. In one approach, a wearable drug delivery device may include a reservoir configured to store a liquid drug, a pump mechanism coupled to the reservoir and operable to expel the liquid drug from the reservoir, and a mechanical triggering device engageable by a user. The mechanical triggering device is operable to change between a first configuration and a second configuration to control deployment of a needle to deliver the liquid drug into a patient.
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公开(公告)号：US20180256823A1
公开(公告)日：2018-09-13
申请号：US15980469
申请日：2018-05-15
Applicant: Insulet Corporation
Inventor： David NAZZARO , Ian MCLAUGHLIN , Simon KOZIN , Maureen MCCAFFREY , Jackie MAC , Alexander DOUDOUMOPOULOS , Bhavin PATEL
CPC classification number: A61M5/31593 , A61M5/14248 , A61M5/28 , A61M5/31531 , A61M5/32 , A61M5/42 , A61M37/00 , A61M2005/2474 , A61M2005/3142 , A61M2005/31518
Abstract: A wearable drug delivery device that can deliver a liquid drug stored in a container to a patient is provided. The container can be a prefilled cartridge that can be loaded into the drug delivery device by the patient or that can be preloaded within the drug delivery device when provided to the patient. A sealed end of the container is pierced to couple the stored liquid drug to a needle conduit that is coupled to a needle insertion component that provides access to the patient. A drive system of the drug delivery device can expel the liquid drug from the cartridge to the patient through the needle conduit. The drive system can be controlled to provide the liquid drug to the patient in a single dose or over multiple doses.
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