公开(公告)号：US20210170104A1

公开(公告)日：2021-06-10

申请号：US17112314

申请日：2020-12-04

Applicant: INSULET CORPORATION

Inventor： Yibin ZHENG ,  Joon Bok LEE ,  Steven CARDINALI ,  Jason O'CONNOR ,  Eric BENJAMIN ,  Ian MCLAUGHLIN ,  David NAZZARO ,  Ashutosh ZADE

IPC: A61M5/172 ,  A61M5/142 ,  G16H40/67 ,  G16H20/17 ,  G16H50/70 ,  G16H10/60 ,  G16H50/30 ,  G16H40/40 ,  G16H20/60 ,  G01N33/49

Abstract: Disclosed are a device, system, methods and computer-readable medium products that provide an updated insulin-to-carbohydrate ratio and an updated total daily insulin. The described processes may be used for periodic updating of the insulin-to-carbohydrate ratio and the total daily insulin. The insulin-to-carbohydrate ratio and/or the total may be used in the calculation of new doses of insulin that a drug delivery device may be commanded to deliver to a user.

公开(公告)号：US20250108165A1

公开(公告)日：2025-04-03

申请号：US18929087

申请日：2024-10-28

Applicant: INSULET CORPORATION

Inventor： Steven CARDINALI ,  David NAZZARO ,  Ian MCLAUGHLIN

IPC: A61M5/172

Abstract: Embodiments of the present disclosure relate to approaches for more efficiently measuring glucose levels using a wearable drug delivery device. In some embodiments, the wearable drug delivery device may include a needle deployment component including a cannula and an optical conduit deployable into a user, the cannula operable to deliver a liquid drug to the user. The wearable drug delivery device may further include a glucose monitor including an optical sensor, the optical sensor operable to measure a light output received via the optical conduit.

公开(公告)号：US20240252753A1

公开(公告)日：2024-08-01

申请号：US18633816

申请日：2024-04-12

Applicant: INSULET CORPORATION

Inventor： Yibin ZHENG ,  Joon Bok LEE ,  Steven CARDINALI ,  Jason O'CONNOR ,  Eric BENJAMIN ,  Ian MCLAUGHLIN ,  David NAZZARO ,  Ashutosh ZADE

IPC: A61M5/172 ,  A61M5/142 ,  G01N33/49 ,  G16H10/60 ,  G16H20/17 ,  G16H20/60 ,  G16H40/40 ,  G16H40/67 ,  G16H50/30 ,  G16H50/70

CPC classification number: A61M5/1723 ,  A61M5/14248 ,  G01N33/49 ,  G16H10/60 ,  G16H20/17 ,  G16H20/60 ,  G16H40/40 ,  G16H40/67 ,  G16H50/30 ,  G16H50/70 ,  A61M2005/1726 ,  A61M2205/505 ,  A61M2205/52 ,  A61M2230/201

Abstract: Disclosed are a device, system, methods and computer-readable medium products that provide an updated insulin-to-carbohydrate ratio and an updated total daily insulin. The described processes may be used for periodic updating of the insulin-to-carbohydrate ratio and the total daily insulin. The insulin-to-carbohydrate ratio and/or the total may be used in the calculation of new doses of insulin that a drug delivery device may be commanded to deliver to a user.

公开(公告)号：US20240108800A1

公开(公告)日：2024-04-04

申请号：US18474682

申请日：2023-09-26

Applicant: INSULET CORPORATION

Inventor： Soroush KAMRAVA ,  Steven CARDINALI ,  Daniel ALLIS

IPC: A61M5/142 ,  A61M5/145

CPC classification number: A61M5/14216 ,  A61M5/1454 ,  A61M2005/14506 ,  A61M2205/0266

Abstract: A drug delivery device drive mechanism including a first ratchet wheel having a first ratchet gear coupled to a first spur gear, a second ratchet wheel having a second ratchet gear coupled to a second spur gear, wherein the first ratchet wheel and the second ratchet wheel are coplanar and gear teeth of the first spur gear mesh with gear teeth the second spur gear, and an actuation mechanism including a pusher interface coupled to an actuator, the pusher interface having at least one pusher tab operable to physically contact the first ratchet gear.

公开(公告)号：US20240091435A1

公开(公告)日：2024-03-21

申请号：US18466217

申请日：2023-09-13

Applicant: INSULET CORPORATION

Inventor： Maureen MCCAFFREY ,  Soroush KAMRAVA ,  Steven CARDINALI ,  Jeffrey BARNES ,  Kyle BREINGAN ,  Lucas MCGAHREN ,  Daniel BARRETT

IPC: A61M5/145 ,  F04B17/00

CPC classification number: A61M5/1452 ,  F04B17/00 ,  F16H2025/2071

Abstract: Disclosed herein are various embodiments of clutching mechanisms applicable to a dual reservoir pumping mechanism for a drug delivery device, the clutching mechanisms serving to allow translation of one of the reservoirs during the filling process and thereafter connecting the reservoirs together such that one can be driven relative to the other one by means of a leadscrew or other driving mechanism.

公开(公告)号：US20230162833A1

公开(公告)日：2023-05-25

申请号：US18151582

申请日：2023-01-09

Applicant: INSULET CORPORATION

Inventor： David NAZZARO ,  Steven CARDINALI ,  Nicholas CONTE ,  Daniel ALLIS ,  Jason O'CONNOR ,  Joon Bok LEE ,  Ashutosh ZADE ,  Timothy HENNING ,  Thomas METZMAKER ,  Ian MCLAUGHLIN

IPC: G16H20/60 ,  G16H20/17

CPC classification number: G16H20/60 ,  G16H20/17

Abstract: Disclosed are examples of a device, a system, methods and computer-readable medium products operable to implement functionality to determine and respond to a purpose of a meal. An algorithm or application may receive data that may include data related to a meal purpose from data sources and determine whether any of the data received from the plurality of data sources was received from a direct data source or an indirect data source. The data may be evaluated to determine a purpose of the meal. Based on the results of the evaluation, instructions may be generated to provide an appropriate response based on the determined purpose of the meal. The generated instructions to provide the appropriate response based on the determined purpose of the meal may be output.

公开(公告)号：US20230014094A1

公开(公告)日：2023-01-19

申请号：US17812064

申请日：2022-07-12

Applicant: Insulet Corporation

Inventor： Cameron DIMAIO ,  Steven CARDINALI

IPC: A61M5/145 ,  A61M5/142 ,  A61M5/158 ,  A61M5/14

Abstract: Disclosed herein is a reservoir for use in a wearable drug delivery device having multiple chambers of potentially varying lengths or arrangement so as to efficiently utilize available space within a housing of the drug delivery device. Each of the chambers is connected to a fluid path and a liquid drug is drawn from each of the chambers by suction applied to the fluid path. Each of the chambers is fitted with a free piston which is moved within the chamber by the suction applied to the fluid path as it draws the liquid drug out of the chamber, thereby eliminating the need for a mechanical arrangement for moving the piston within each of the chambers.

公开(公告)号：US20220096749A1

公开(公告)日：2022-03-31

申请号：US17487570

申请日：2021-09-28

Applicant: Insulet Corporation

Inventor： Steven CARDINALI ,  David NAZZARO ,  Ian MCLAUGHLIN

IPC: A61M5/172

Abstract: Embodiments of the present disclosure relate to approaches for more efficiently measuring glucose levels using a wearable drug delivery device. In some embodiments, the wearable drug delivery device may include a needle deployment component including a cannula and an optical conduit deployable into a user, the cannula operable to deliver a liquid drug to the user. The wearable drug delivery device may further include a glucose monitor including an optical sensor, the optical sensor operable to measure a light output received via the optical conduit.

公开(公告)号：US20210236726A1

公开(公告)日：2021-08-05

申请号：US16780278

申请日：2020-02-03

Applicant: Insulet Corporation

Inventor： Steven CARDINALI ,  Ashutosh ZADE ,  Joon Bok LEE ,  Jason O'CONNOR ,  Yibin ZHENG

IPC: A61M5/172

Abstract: Exemplary embodiments may provide an improved approach to automated insulin delivery by more accurately estimating the total daily insulin (TDI) of a user. As a result, less insulin is wasted by the delivery system, and the estimate of TDI more closely matches a user's actual daily insulin needs. Hence, the user need not refill the insulin reservoir excessively or need not fret unnecessarily about running out of insulin prematurely. The estimate relies on the history of actual automated insulin deliveries and thus reflects the actual insulin delivered to the user more accurately than conventional approaches.

公开(公告)号：US20190151568A1

公开(公告)日：2019-05-23

申请号：US16191891

申请日：2018-11-15

Applicant: Insulet Corporation

Inventor： Steven CARDINALI ,  David NAZZARO ,  Larry RING

IPC: A61M5/36 ,  A61K38/28 ,  A61M5/142 ,  A61M5/158 ,  A61M5/168

Abstract: A wearable drug delivery device that can deliver a liquid drug stored in a container to a patient or user is provided. A soft needle or cannula can be placed in fluid communication with the liquid drug and can be coupled to a needle insertion component that provides access to the patient. A drive system of the drug delivery device can expel the liquid drug from the container to the patient through the soft needle or cannula. The wearable drug delivery device can include components for preventing backflow and eliminating air within the liquid drug. As a result, the comfort of the patient can be enhanced and correct drug dosages can be provided when using the drug delivery device.