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21.
公开(公告)号:US20080113990A1
公开(公告)日:2008-05-15
申请号:US11546669
申请日:2006-10-12
申请人: Esther Martinborough , Danielle Lehsten , Timothy Neubert , Aarti Sameer Kawatkar , Nicole Zimmermann , Andreas Termin
发明人: Esther Martinborough , Danielle Lehsten , Timothy Neubert , Aarti Sameer Kawatkar , Nicole Zimmermann , Andreas Termin
IPC分类号: A61K31/53 , A61K31/501 , A61K31/433 , A61K31/427 , A61K31/4245
CPC分类号: C07D417/12 , C07D275/03 , C07D277/44
摘要: Biphenyl derivatives useful as ion channel antagonists are disclosed herein. The compositions thereof are useful for treating or relieving pain-related conditions.
摘要翻译: 本文公开了可用作离子通道拮抗剂的联苯衍生物。 其组合物可用于治疗或缓解疼痛相关病症。
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22.
公开(公告)号:US20100130548A1
公开(公告)日:2010-05-27
申请号:US12697671
申请日:2010-02-01
申请人: Esther Martinborough , Danielle Lehsten , Timothy Neubert , Aarti Sameer Kawatkar , Nicole Zimmermann , Andreas Termin
发明人: Esther Martinborough , Danielle Lehsten , Timothy Neubert , Aarti Sameer Kawatkar , Nicole Zimmermann , Andreas Termin
IPC分类号: A61K31/4709 , A61K31/426 , C12N5/00
CPC分类号: C07D417/12 , C07D275/03 , C07D277/44
摘要: Biphenyl derivatives useful as ion channel antagonists are disclosed herein. The compositions thereof are useful for treating or relieving pain-related conditions.
摘要翻译: 本文公开了可用作离子通道拮抗剂的联苯衍生物。 其组合物可用于治疗或缓解疼痛相关病症。
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23.
公开(公告)号:US20070203130A1
公开(公告)日:2007-08-30
申请号:US11517754
申请日:2006-09-08
IPC分类号: A61K31/541 , A61K31/5377 , A61K31/53 , A61K31/501 , A61K31/497 , A61K31/496 , C07D417/02 , C07D413/02 , C07D403/02
CPC分类号: C07D417/12 , C07D277/52
摘要: Bicyclic derivatives useful as ion channel antagonists are disclosed herein. The compositions thereof are useful for treating or relieving pain-related conditions.
摘要翻译: 本文公开了用作离子通道拮抗剂的双环衍生物。 其组合物可用于治疗或缓解疼痛相关病症。
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24.
公开(公告)号:US08236833B2
公开(公告)日:2012-08-07
申请号:US12697671
申请日:2010-02-01
申请人: Esther Martinborough , Danielle Lehsten , Timothy Neubert , Aarti Sameer Kawatkar , Nicole Hilgraf , Andreas Termin
发明人: Esther Martinborough , Danielle Lehsten , Timothy Neubert , Aarti Sameer Kawatkar , Nicole Hilgraf , Andreas Termin
IPC分类号: A61K31/425
CPC分类号: C07D417/12 , C07D275/03 , C07D277/44
摘要: Biphenyl derivatives useful as ion channel antagonists are disclosed herein. The compositions thereof are useful for treating or relieving pain-related conditions.
摘要翻译: 本文公开了可用作离子通道拮抗剂的联苯衍生物。 其组合物可用于治疗或缓解疼痛相关病症。
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公开(公告)号:US07989481B2
公开(公告)日:2011-08-02
申请号:US12550649
申请日:2009-08-31
IPC分类号: A61K31/426 , A61K31/427
CPC分类号: C07D277/52 , C07C311/46 , C07C311/47 , C07C2602/08 , C07D417/12
摘要: The present invention relates to indane derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
摘要翻译: 本发明涉及可用作离子通道抑制剂的二氢化茚衍生物。 本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病的方法。
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公开(公告)号:US20070203122A1
公开(公告)日:2007-08-30
申请号:US11584961
申请日:2006-10-23
IPC分类号: A61K31/55 , A61K31/4709 , A61K31/405 , A61K31/4025 , A61K31/4015 , A61K31/4545 , C07D403/14
CPC分类号: C07D401/08 , C07D207/10 , C07D207/12 , C07D211/54 , C07D401/06 , C07D401/12 , C07D403/06 , C07D403/08
摘要: Sulfonamide derivatives act as ion channel antagonists. The compositions are useful for treating or relieving pain-related conditions.
摘要翻译: 磺酰胺衍生物作为离子通道拮抗剂。 该组合物可用于治疗或缓解疼痛相关病症。
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公开(公告)号:US20070117801A1
公开(公告)日:2007-05-24
申请号:US11450695
申请日:2006-06-09
IPC分类号: A61K31/53 , A61K31/50 , A61K31/433 , A61K31/4245 , A61K31/415 , A61K31/42
CPC分类号: C07D277/52 , C07C311/46 , C07C311/47 , C07C2602/08 , C07D417/12
摘要: The present invention relates to indane derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
摘要翻译: 本发明涉及可用作离子通道抑制剂的二氢化茚衍生物。 本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病的方法。
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28.
公开(公告)号:US07855220B2
公开(公告)日:2010-12-21
申请号:US11517754
申请日:2006-09-08
IPC分类号: A61K31/426 , A61K31/4245 , A61K31/425 , C07D277/52 , C07D271/07 , C07D271/113 , C07D275/03
CPC分类号: C07D417/12 , C07D277/52
摘要: Bicyclic derivatives useful as ion channel antagonists are disclosed herein. The compositions thereof are useful for treating or relieving pain-related conditions.
摘要翻译: 本文公开了用作离子通道拮抗剂的双环衍生物。 其组合物可用于治疗或缓解疼痛相关病症。
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29.
公开(公告)号:US07683083B2
公开(公告)日:2010-03-23
申请号:US11546669
申请日:2006-10-12
申请人: Esther Martinborough , Danielle Lehsten , Timothy Neubert , Aarti Sameer Kawatkar , Nicole Zimmermann , Andreas Termin
发明人: Esther Martinborough , Danielle Lehsten , Timothy Neubert , Aarti Sameer Kawatkar , Nicole Zimmermann , Andreas Termin
IPC分类号: A61K31/425 , C07D277/04
CPC分类号: C07D417/12 , C07D275/03 , C07D277/44
摘要: Biphenyl derivatives useful as ion channel antagonists are disclosed herein. The compositions thereof are useful for treating or relieving pain-related conditions.
摘要翻译: 本文公开了可用作离子通道拮抗剂的联苯衍生物。 其组合物可用于治疗或缓解疼痛相关病症。
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公开(公告)号:US20090326023A1
公开(公告)日:2009-12-31
申请号:US12550649
申请日:2009-08-31
IPC分类号: A61K31/426
CPC分类号: C07D277/52 , C07C311/46 , C07C311/47 , C07C2602/08 , C07D417/12
摘要: The present invention relates to indane derivatives useful as inhibitors of ion channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
摘要翻译: 本发明涉及可用作离子通道抑制剂的二氢化茚衍生物。 本发明还提供包含本发明化合物的药学上可接受的组合物和使用该组合物治疗各种疾病的方法。
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