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公开(公告)号：US20140316249A1
公开(公告)日：2014-10-23
申请号：US14356223
申请日：2012-11-06
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Thomas Erik Amthor , Steffen Weiss , Johannes Adrianus Overweg
CPC classification number: G01R33/287 , A61N5/1001 , A61N5/1007 , A61N5/1039 , A61N2005/1022 , A61N2005/1055 , A61N2005/1089 , A61N2005/1094 , G01R33/48
Abstract: A miniature X-ray source (10) for high dose rate brachytherapy that can be operated in a wide range of operating directions (76) in the presence of a strong magnetic field (B), such as, for instance, the static magnetic field (B) of an MR scanner, with at least one anode (12) and at least one cathode (14), wherein in an operative state, an electric field (18) between the anode (12) and the cathode (14) is essentially spherically symmetric in at least a continuous solid angle of more than π/2 sr about a center (16) of the cathode (14); a brachytherapy system, comprising at least one said miniature X-ray source (10), and a method for generating a beam (82) of X-ray radiation inside an outer magnetic field (B) or an operative MR scanner with said miniature X-ray source (10).
Abstract translation: 一种用于高剂量率近距离放射治疗的微型X射线源（10），其可以在强磁场（B）的存在下在宽范围的操作方向（76）下操作，例如静态磁场 （12）和至少一个阴极（14）的MR扫描器（B），其中在工作状态下，阳极（12）和阴极（14）之间的电场（18）是 在阴极（14）的中心（16）的至少一个连续立体角以上大体上相对于对称; 包括至少一个所述微型X射线源（10）的近距离放射治疗系统，以及用于在外部磁场（B）或具有所述微型X的操作MR扫描器中产生X射线辐射束（82）的方法 射源（10）。
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公开(公告)号：US20250138122A1
公开(公告)日：2025-05-01
申请号：US18835366
申请日：2023-01-27
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Thomas Erik Amthor , Peter Ulrich Börnert , Christophe Michael Jean Schulke , George Randall Duensing
Abstract: The invention relates to a method for optimizing an examination protocol for executing a magnetic resonance (MR) image acquisition from a body of a patient. It is an object of the invention to facilitate efficient implementation of accelerated (e.g., artificial intelligencebased) examination protocols that are a true or very close replacement for examination protocols already existing in clinical practice. It should be made possible to provide each individual clinic with specific optimized versions of their own standard examination protocols. As a solution, the method of the invention comprises the steps of: providing an examination protocol containing specifications of two or more imaging sequences; in a computer, executing at least one algorithm processing said examination protocol as an input to perform an optimization with regard to the speed of execution of the examination protocol, taking into account diagnostic relevance weightings assigned to the imaging sequences contained in the examination protocol; and making an output available representing said optimized examination protocol to a user and/or executing the MR image acquisition on an MR scanner based on said optimized examination protocol. Moreover, the invention relates to an MR scanner (1), to a computer (15) and to a computer program for an MR scanner (1).
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公开(公告)号：US20250130643A1
公开(公告)日：2025-04-24
申请号：US18834663
申请日：2023-01-29
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Christoph Günther Leussler , Thomas Erik Amthor
Abstract: The invention relates to an imaging accessory positioning system (11) and method for medical imaging. Haptic feedback (151) is used to assist a user (16) with positioning an imaging accessory (12) relative to a reference position (122). A position sensor (13) measures the position (121) of the imaging accessory (12) and provides a position signal (131). A processing unit (14) derives the position (121) of the imaging accessory (12) from the position signal (131), computes a feedback signal (141) based on the deviation between the position (121) of the imaging accessory (12) and the reference position (122), and provides the feedback signal (141) to a haptic feedback unit (15). The haptic feedback unit (15) generates haptic feedback (151) to assist the user (16). In one embodiment, the reference position (122) relative to a patient is automatically determined.
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公开(公告)号：US11802929B2
公开(公告)日：2023-10-31
申请号：US17916819
申请日：2021-03-31
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Thomas Erik Amthor , Annerieke Huevelink-Marck , Jouke Smink
IPC: G01V3/00 , G01R33/567 , G01R33/385 , G01R33/48
CPC classification number: G01R33/5673 , G01R33/385 , G01R33/4818
Abstract: Disclosed herein is a magnetic resonance imaging system (100) controlled by a processor (130). The execution of the machine executable instructions causes the processor to sort (200) multiple preparatory scan commands (142) into fixed duration preparatory scan commands (144) and indeterminate duration preparatory scan commands (146). The execution of the machine executable instructions further causes the processor to first control (202) the magnetic resonance imaging system with the indeterminate duration preparatory scan commands and then (204) with the fixed duration preparatory scan commands. The execution of the machine executable instructions further causes the processor to calculate (206) a gradient pulse starting time (160). The execution of the machine executable instructions further causes the processor to provide (208) the warning signal at a predetermined time (162) before the gradient pulse starting time. The execution of the machine executable instructions further causes the processor to control (210) the magnetic resonance imaging system with pulse sequence commands to acquire the k-space data such that the execution of the gradient coil pulse commands begins at the pulse starting time.
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公开(公告)号：US20230130716A1
公开(公告)日：2023-04-27
申请号：US17916819
申请日：2021-03-31
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Thomas Erik Amthor , Annerieke Huevelink-Marck , Jouke Smink
IPC: G01R33/567 , G01R33/48 , G01R33/385
Abstract: Disclosed herein is a magnetic resonance imaging system (100) controlled by a processor (130). The execution of the machine executable instructions causes the processor to sort (200) multiple preparatory scan commands (142) into fixed duration preparatory scan commands (144) and indeterminate duration preparatory scan commands (146). The execution of the machine executable instructions further causes the processor to first control (202) the magnetic resonance imaging system with the indeterminate duration preparatory scan commands and then (204) with the fixed duration preparatory scan commands. The execution of the machine executable instructions further causes the processor to calculate (206) a gradient pulse starting time (160). The execution of the machine executable instructions further causes the processor to provide (208) the warning signal at a predetermined time (162) before the gradient pulse starting time. The execution of the machine executable instructions further causes the processor to control (210) the magnetic resonance imaging system with pulse sequence commands to acquire the k-space data such that the execution of the gradient coil pulse commands begins at the pulse starting time.
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Patent Agency Ranking
公开(公告)号：US11435422B2
公开(公告)日：2022-09-06
申请号：US17027743
申请日：2020-09-22
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Thomas Erik Amthor , Mariya Ivanova Doneva , Jan Jakob Meineke
Abstract: The invention provides for a medical imaging system comprising: a memory for storing machine executable instructions; a processor for controlling the medical instrument. Execution of the machine executable instructions causes the processor to: receive MRF magnetic resonance data acquired according to an MRF magnetic resonance imaging protocol of a region of interest; reconstruct an MRF vector for each voxel of a set of voxels descriptive of the region of interest using the MRF magnetic resonance data according to the MRF magnetic resonance imaging protocol; calculate a preprocessed MRF vector (126) for each of the set of voxels by applying a predetermined preprocessing routine to the MRF vector for each voxel, wherein the predetermined preprocessing routine comprises normalizing the preprocessed MRF vector for each voxel; calculate an outlier map for the set of voxels by assigning an outlier score to the preprocessed MRF vector using a machine learning algorithm.
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公开(公告)号：US11238977B2
公开(公告)日：2022-02-01
申请号：US16643150
申请日：2018-08-28
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Thomas Erik Amthor , Jörn Borgert , Joachim Schmidt , Ingmar Graesslin , Eberhard Sebastian Hansis , Thomas Netsch
Abstract: A medical imaging system for acquiring medical image data from an imaging zone. The medical imaging system includes a memory for storing machine executable instructions and medical imaging system commands. The medical imaging system further includes a user interface and a processor. Execution of the machine executable instructions causes the processor to: receive scan parameter data for modifying the behavior of the medical imaging system commands; receive metadata descriptive of imaging conditions from the user interface; store configuration data descriptive of a current configuration of the medical imaging system in the memory; calculate an error probability by comparing the metadata, the configuration data, and the scan parameter data using a predefined model, wherein the error probability is descriptive of a deviation between the metadata and between the configuration data and/or the scan parameter data; perform predefined action if the error probability is above a predetermined threshold.
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公开(公告)号：US11092659B2
公开(公告)日：2021-08-17
申请号：US16498555
申请日：2018-03-30
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Thomas Erik Amthor , Mariya Ivanova Doneva , Karsten Sommer , Peter Koken
IPC: G01R33/483 , G01R33/24 , G01R33/44 , G01R33/48 , G01R33/56 , G01R33/565
Abstract: A magnetic resonance imaging (MRI) system (100) includes a memory (134) for storing machine executable instructions (140) and magnetic resonance fingerprinting (MRF) pulse sequence commands (142) which cause the MRI system to acquire MRF magnetic resonance data (144) according to an MRF protocol. The pulse sequence commands are configured for acquiring the MRF magnetic resonance data in two-dimensional slices (410, 412, 414, 416, 418, 420), having a slice selection direction. A train of pulse sequence repetitions includes a sampling event where the MRF data is repeatedly sampled. Execution of the machine executable instructions causes a processor to control the MRI system to: acquire (200) the MRF magnetic resonance data; construct (202) a series (148) of at least one magnetic resonance parameter value for each voxel of the two dimensional slices; and calculate (204) a composition (502, 504, 506, 508) of each of a set of predetermined substances within two or more sub-voxels (306, 308) for each voxel of the two dimensional slices using a sub-voxel magnetic resonance fingerprinting dictionary (150) for each of the two or more sub-voxels and the series of the at least one magnetic resonance parameter value. Each voxel in the slice selection direction is divided into two or more sub-voxels.
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公开(公告)号：US10788556B2
公开(公告)日：2020-09-29
申请号：US16072940
申请日：2017-02-06
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Thomas Erik Amthor , Peter Koken , Karsten Sommer , Mariya Ivanova Doneva , Peter Boernert
IPC: G01R33/56 , G01R33/46 , G01R33/48 , G01R33/54 , G01R33/561
Abstract: A magnetic resonance imaging system (100) acquires magnetic resonance data (142) from a subject (118) within a measurement zone (108). Pulse sequence commands (140) control the magnetic resonance imaging system to acquire the magnetic resonance data according to a magnetic resonance fingerprinting protocol. The pulse sequence commands are configured for controlling the magnetic resonance imaging system to repeatedly generate an RF pulse train (300) and acquire the magnetic resonance data as multiple k-space traces. The machine executable instructions causes the processor to: sequentially acquire (200) the multiple k-space traces of magnetic resonance data by controlling the magnetic resonance imaging system with pulse sequence commands and calculate (202) the abundance of each of a set of predetermined substances for k-space traces that are acquired after a predetermined number of k-space traces of the multiple k-space traces has been acquired and the acquired magnetization has reached a steady state. The abundance of each of a set of predetermined substances is determined by comparing the magnetic resonance data with a steady state magnetic resonance fingerprinting dictionary (144) which contains a listing of calculated magnetic resonance signals in response to the RF pulse train for a set of predetermined substances.
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30.发明授权公开(公告)号：US10509086B2
公开(公告)日：2019-12-17
申请号：US15735422
申请日：2016-06-08
Applicant: KONINKLIJKE PHILIPS N.V.
Inventor： Thomas Erik Amthor , Peter Boernert , Mariya Ivanova Doneva , Wim Crooijmans
IPC: G01R33/46 , G01R33/30 , G01R33/31 , G01R33/3875 , G01R33/389 , G01R33/36 , G01R33/465 , G01R33/48
Abstract: The invention provides for a method of operating an instrument (100). The instrument comprises a magnetic resonance system (102) for measuring dictionary magnetic resonance data (154) from a measurement zone (108). The magnetic resonance system comprises a magnet (104) for generating a main magnetic field within the measurement zone. The magnetic resonance system comprises a test fixture (124) for holding a test sample (132) within the measurement zone. The test fixture comprises a supplementary magnetic field coil (126) and a magnetic resonance antenna (128). The method comprises the steps of repeatedly: choosing (200) an electrical current; supplying (202) the electrical current to the supplementary magnetic field coil to adjust the main magnetic field within the measurement zone; acquiring (204) the dictionary magnetic resonance data from the test sample with the magnetic resonance antenna by controlling the magnetic resonance system according to a magnetic resonance fingerprinting technique; and appending (206) the dictionary magnetic resonance data to a magnetic resonance fingerprinting dictionary (156).
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