Modified flagellin improved toll-like receptor 5 stimulating activity
    21.
    发明授权
    Modified flagellin improved toll-like receptor 5 stimulating activity 有权
    改良的鞭毛蛋白改善了toll样受体5刺激活性

    公开(公告)号:US08236327B2

    公开(公告)日:2012-08-07

    申请号:US12526187

    申请日:2009-08-06

    IPC分类号: A61K39/106

    CPC分类号: C07K14/28

    摘要: Disclosed herein are flagellin mutants having an enhanced activity of stimulating the toll-like receptor-5 (hereinafter referred to as “TLR5”). More specifically, disclosed are flagellin mutants, prepared by point-mutating some of the amino acids of a TRL5 agonist flagellin so as to enhance the TRL-stimulating activity of the flagellin.

    摘要翻译: 本文公开了具有增强的刺激长耳状受体-5的活性的鞭毛蛋白突变体(以下称为“TLR5”)。 更具体地,公开了通过点突变TRL5激动剂鞭毛蛋白的一些氨基酸制备的鞭毛蛋白突变体,以增强鞭毛蛋白的TRL刺激活性。

    Method of measuring shear friction factor through backward extrusion process
    22.
    发明授权
    Method of measuring shear friction factor through backward extrusion process 失效
    通过反向挤压工艺测量剪切摩擦系数的方法

    公开(公告)号:US06418795B2

    公开(公告)日:2002-07-16

    申请号:US09783542

    申请日:2001-02-15

    IPC分类号: G01N324

    CPC分类号: G01N3/24

    摘要: A method of measuring shear friction factor between a workpiece material and a forming tool through a backward extrusion process. The method includes steps of: positioning the workpiece material at a groove previously manufactured on the forming die by turning; pressurizing the workpiece material to form an extruded product by pressure of a downwardly moving punch; forming tip on the extruded end of the extruded product; measuring an external diameter of the extruded product and a diameter of the tip, and obtaining a perpendicular distance by subtracting the diameter of the tip from the external diameter and dividing the subtracting result by two; and acquiring shear friction factor by calculating predetermined coefficients and a normalized perpendicular distance non-dimensionalized by thickness value of the extruded product. The thickness is defined as an interval between the external diameter of the extruded product and an external diameter of the punch.

    摘要翻译: 通过反向挤压工艺测量工件材料与成形工具之间的剪切摩擦系数的方法。 该方法包括以下步骤:通过转动将工件材料定位在预先制造在成型模具上的凹槽处; 通过向下移动的冲头的压力对工件材料加压以形成挤出产品; 在挤出产品的挤出端上形成尖端; 测量挤出产品的外径和尖端的直径,并且通过从外径减去尖端的直径并将减法结果除以2获得垂直距离; 并通过计算预定系数和通过挤出产品的厚度值无量纲化的归一化垂直距离来获得剪切摩擦系数。 厚度定义为挤出产品的外径和冲头的外径之间的间隔。

    Modified flagellin improved toll-like receptor 5 stimulating activity
    23.
    发明授权
    Modified flagellin improved toll-like receptor 5 stimulating activity 有权
    改良的鞭毛蛋白改善了toll样受体5刺激活性

    公开(公告)号:US08337864B2

    公开(公告)日:2012-12-25

    申请号:US13333709

    申请日:2011-12-21

    IPC分类号: A61K39/106

    CPC分类号: C07K14/28

    摘要: Disclosed herein are flagellin mutants having an enhanced activity of stimulating the toll-like receptor-5 (hereinafter referred to as “TLR5”). More specifically, disclosed are flagellin mutants, prepared by point-mutating some of the amino acids of a TRL5 agonist flagellin so as to enhance the TRL-stimulating activity of the flagellin.

    摘要翻译: 本文公开了具有增强的刺激长耳状受体-5(以下称为TLR5)的活性的鞭毛蛋白突变体。 更具体地,公开了通过点突变TRL5激动剂鞭毛蛋白的一些氨基酸制备的鞭毛蛋白突变体,以增强鞭毛蛋白的TRL刺激活性。

    Method of manufacturing a flexible device and method of manufacturing a flexible display
    25.
    发明授权
    Method of manufacturing a flexible device and method of manufacturing a flexible display 有权
    柔性装置的制造方法和制造柔性显示器的方法

    公开(公告)号:US07989314B2

    公开(公告)日:2011-08-02

    申请号:US12522174

    申请日:2008-01-08

    IPC分类号: H01L21/762

    摘要: Provided are a method of separating a metal layer and an organic light emitting diode. A method of manufacturing a flexible device and a method of manufacturing a flexible display include forming a releasing layer on a substrate, forming a metal layer on the releasing layer, forming an insulating layer on the metal layer, forming a releasable layer on the insulating layer, bonding a plastic to the releasable layer, and separating the substrate and the releasing layer at an interface therebetween to manufacture a flexible device. Since the conventional process equipment using the glass substrate can be compatibly used, the manufacturing cost can be reduced. In addition, since the glass substrate has less limitation in the process temperature compared with the plastic substrate, an electric device having a superior performance can be manufactured. Furthermore, the glass substrate has good thermal/chemical stability and is less deformed compared with the plastic substrate, whereby process control such as substrate alignment becomes easy.

    摘要翻译: 提供了分离金属层和有机发光二极管的方法。 柔性器件的制造方法和柔性显示器的制造方法包括在基板上形成剥离层,在剥离层上形成金属层,在金属层上形成绝缘层,在绝缘层上形成剥离层 ,将塑料粘合到可剥离层上,并在其间的界面处分离衬底和释放层以制造柔性器件。 由于可以兼容使用玻璃基板的常规工艺设备,所以可以降低制造成本。 此外,由于与塑料基板相比,玻璃基板的加工温度的限制较少,因此可以制造出具有优异性能的电子装置。 此外,玻璃基板与塑料基板相比具有良好的热/化学稳定性并且变形较小,由此诸如基板对准的工艺控制变得容易。

    METHOD OF MANUFACTURING A FLEXIBLE DEVICE AND METHOD OF MANUFACTURING A FLEXIBLE DISPLAY
    26.
    发明申请
    METHOD OF MANUFACTURING A FLEXIBLE DEVICE AND METHOD OF MANUFACTURING A FLEXIBLE DISPLAY 有权
    制造柔性装置的方法和制造柔性显示器的方法

    公开(公告)号:US20100075447A1

    公开(公告)日:2010-03-25

    申请号:US12522174

    申请日:2008-01-08

    IPC分类号: H01L51/48 H01L21/77

    摘要: Provided are a method of separating a metal layer and an organic light emitting diode. A method of manufacturing a flexible device and a method of manufacturing a flexible display include forming a releasing layer on a substrate, forming a metal layer on the releasing layer, forming an insulating layer on the metal layer, forming a releasable layer on the insulating layer, bonding a plastic to the releasable layer, and separating the substrate and the releasing layer at an interface therebetween to manufacture a flexible device. Since the conventional process equipment using the glass substrate can be compatibly used, the manufacturing cost can be reduced. In addition, since the glass substrate has less limitation in the process temperature compared with the plastic substrate, an electric device having a superior performance can be manufactured. Furthermore, the glass substrate has good thermal/chemical stability and is less deformed compared with the plastic substrate, whereby process control such as substrate alignment becomes easy.

    摘要翻译: 提供了分离金属层和有机发光二极管的方法。 柔性器件的制造方法和柔性显示器的制造方法包括在基板上形成剥离层,在剥离层上形成金属层,在金属层上形成绝缘层,在绝缘层上形成剥离层 ,将塑料粘合到可剥离层上,并在其间的界面处分离衬底和释放层以制造柔性器件。 由于可以兼容使用玻璃基板的常规工艺设备,所以可以降低制造成本。 此外,由于与塑料基板相比,玻璃基板的加工温度的限制较少,因此可以制造出具有优异性能的电子装置。 此外,玻璃基板与塑料基板相比具有良好的热/化学稳定性并且变形较小,由此诸如基板对准的工艺控制变得容易。

    Nucleic acid molecule encoding abscisic acid responsive element-binding factor 2
    27.
    发明授权
    Nucleic acid molecule encoding abscisic acid responsive element-binding factor 2 失效
    核酸分子编码脱落酸反应元件结合因子2

    公开(公告)号:US06245905B1

    公开(公告)日:2001-06-12

    申请号:US09661569

    申请日:2000-09-14

    申请人: Soo Young Kim

    发明人: Soo Young Kim

    IPC分类号: C12N1529

    摘要: A nucleic acid molecule encoding the Abscisic acid responsive element binding factor 2 (ABF2) was isolated and its nucleotide sequence determined. ABF2 belongs to the ABF family of factors which bind abscisic acid responsive elements in plants. Expression of ABFs is inducible by abscisic acid and various stress treatments. ABFs have the potential to activate a large number of abscisic acid/stress responsive genes and thus a nucleic acid molecule encoding ABF2 can be used to generate transgenic plants that are tolerant to multiple environmental stresses.

    摘要翻译: 分离编码脱落酸反应元件结合因子2(ABF2)的核酸分子,测定其核苷酸序列。 ABF2属于与植物中脱落酸反应元件结合的ABF家族因子。 ABF的表达可通过脱落酸和各种应激处理诱导。 ABF具有激活大量脱落酸/应激反应基因的潜力,因此编码ABF2的核酸分子可用于产生耐受多种环境胁迫的转基因植物。

    Nucleic acid molecule encoding abscisic acid responsive element-binding factor 3
    28.
    发明授权
    Nucleic acid molecule encoding abscisic acid responsive element-binding factor 3 失效
    编码脱落酸反应元件结合因子的核酸分子3

    公开(公告)号:US06218527B1

    公开(公告)日:2001-04-17

    申请号:US09664800

    申请日:2000-09-19

    申请人: Soo Young Kim

    发明人: Soo Young Kim

    IPC分类号: C12N1529

    摘要: A nucleic acid molecule encoding the Abscisic acid responsive element binding factor 3 (ABF3) was isolated and its nucleotide sequence determined. ABF3 belongs to the ABF family of factors which bind abscisic acid responsive elements in plants. Expression of ABFs is inducible by abscisic acid and various stress treatments. ABFs have the potential to activate a large number of abscisic acid/stress responsive genes and thus a nucleic acid molecule encoding ABF3 can be used to generate transgenic plants that are tolerant to multiple environmental stresses.

    摘要翻译: 分离编码脱落酸反应性因子结合因子3(ABF3)的核酸分子,测定其核苷酸序列。 ABF3属于与植物中脱落酸反应元件结合的ABF家族因子。 ABF的表达可通过脱落酸和各种应激处理诱导。 ABF具有激活大量脱落酸/应激反应基因的潜力,因此编码ABF3的核酸分子可用于产生耐受多种环境胁迫的转基因植物。