公开(公告)号：US08580110B2

公开(公告)日：2013-11-12

申请号：US12937786

申请日：2009-04-14

申请人： Lennart Jönsson ,  Olof Jansson ,  Mattias Holmer ,  Jan Sternby ,  Anders Nilsson ,  Per Hansson

发明人： Lennart Jönsson ,  Olof Jansson ,  Mattias Holmer ,  Jan Sternby ,  Anders Nilsson ,  Per Hansson

IPC分类号： B01D61/32 ,  B01D61/34 ,  B01D61/28

CPC分类号： A61M1/16 ,  A61M1/1006 ,  A61M1/1037 ,  A61M1/1039 ,  A61M1/106 ,  A61M1/1065 ,  A61M1/1086 ,  A61M1/1601 ,  A61M1/34 ,  A61M1/3403 ,  A61M2205/3331 ,  A61M2205/3334 ,  A61M2205/50

摘要： A proposed blood treatment apparatus includes: a blood treatment unit, a pair of fluid pumps and a pair blood pumps. The blood treatment unit is configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid. The fluid pumps are configured to pass blood treatment fluid through the blood treatment unit. The blood pumps are configured to extract untreated blood from a blood source, pass extracted blood through the blood treatment unit and deliver treated blood to a target vessel. Additionally, the fluid pumps are configured to control the operation of the blood pumps via the blood treatment fluid. Moreover, a flow control device is configured to control a trans-membrane flow between the blood side and the a fluid side of the blood treatment unit. Hence, for instance ultrafiltration can be adjusted to a desired level in a very straightforward manner.

摘要翻译： 所提出的血液处理装置包括：血液处理单元，一对流体泵和一对血液泵。 血液处理单元被配置为接收未处理的血液和新鲜血液处理液，并且排出经处理的血液和使用的血液处理液。 流体泵配置成使血液处理液通过血液处理单元。 血泵被构造成从血液源中提取未经处理的血液，将提取的血液通过血液处理单元并将处理的血液输送到目标血管。 另外，流体泵配置成通过血液处理流体来控制血液泵的操作。 此外，流量控制装置被配置为控制血液侧和血液处理单元的流体侧之间的跨膜流动。 因此，例如超滤可以以非常直接的方式调整到期望的水平。

公开(公告)号：US08293114B2

公开(公告)日：2012-10-23

申请号：US13123184

申请日：2009-10-09

申请人： Lennart Jönsson ,  Jan Sternby ,  Eddie Nilsson

发明人： Lennart Jönsson ,  Jan Sternby ,  Eddie Nilsson

IPC分类号： B01D61/30 ,  B01D61/24 ,  B01D61/28 ,  B01D69/06 ,  A61M1/34

CPC分类号： A61M1/3462 ,  A61M1/3621 ,  A61M5/44 ,  A61M2205/366 ,  F28D9/0075 ,  F28D9/0087 ,  F28D9/0093

摘要： A method for exchanging heat between an effluent fluid and a blood fluid and a heat exchanger for heat exchange. The heat exchanger comprises a first and a second fluid circuit extending through the heat exchanger. The heat exchanger further comprises a stack of fluid plates and a membrane arranged between each of the fluid plates where one interspace is formed between each fluid plate and membrane. The first and the second fluid circuit is each constituted by a passage extending through the fluid plates and membranes and along the fluid plates and membranes in at least two interspaces According to the method for heat exchanging an effluent fluid is passed through the first fluid circuit and a blood fluid is passed through the second fluid circuit such that the effluent fluid is passed along one side of a membrane and simultaneously the blood fluid is passed along the other side of the membrane. Heat is thus exchanged between the effluent fluid and the blood fluid over the membrane.

摘要翻译： 用于在流出液和血液之间进行热交换的方法和用于热交换的热交换器。 热交换器包括延伸穿过热交换器的第一和第二流体回路。 热交换器还包括一组流体板和布置在每个流体板之间的膜，其中在每个流体板和膜之间形成有一个间隙。 第一和第二流体回路各自由在至少两个间隙中延伸穿过流体板和膜并沿着流体板和膜的通道构成根据用于热交换的方法，排出流体通过第一流体回路和 血液流过第二流体回路，使得流出液体沿着膜的一侧通过，同时血液流体沿膜的另一侧通过。 因此，热量在流出液体和膜之间的血液流体之间交换。

公开(公告)号：US08293113B2

公开(公告)日：2012-10-23

申请号：US13123071

申请日：2009-10-09

申请人： Lennart Jönsson ,  Jan Sternby ,  Eddie Nilsson

发明人： Lennart Jönsson ,  Jan Sternby ,  Eddie Nilsson

IPC分类号： B01D61/30 ,  B01D61/24 ,  B01D61/28 ,  B01D69/06 ,  A61M1/34

CPC分类号： A61M1/3462 ,  A61M1/3621 ,  A61M5/44 ,  A61M2205/366 ,  F28D9/0075 ,  F28D9/0087 ,  F28D9/0093

摘要： A method for exchanging heat between an effluent fluid and a treatment fluid and a heat exchanger for heat exchange as well as an arrangement and a kit comprising a heat exchanger. The heat exchanger comprises a first and a second fluid circuit extending through the heat exchanger. The heat exchanger further comprises a stack of fluid plates and a membrane arranged between each of the fluid plates where one interspace is formed between each fluid plate and membrane. The first and the second fluid circuit is each constituted by a passage extending through the fluid plates and membranes and along the fluid plates and membranes in at least two interspaces. According to the method for heat exchanging an effluent fluid is passed through the first fluid circuit and a treatment fluid is passed through the second fluid circuit such that the effluent fluid is passed along one side of a membrane and simultaneously the treatment fluid is passed along the other side of the membrane. Heat is thus exchanged between the effluent fluid and the treatment fluid over the membrane.

摘要翻译： 用于在流出物流体和处理流体之间进行热交换的方法以及用于热交换的热交换器以及包括热交换器的布置和套件。 热交换器包括延伸穿过热交换器的第一和第二流体回路。 热交换器还包括一组流体板和布置在每个流体板之间的膜，其中在每个流体板和膜之间形成有一个间隙。 第一和第二流体回路各自由在至少两个间隙中延伸穿过流体板和膜以及流体板和膜的通道构成。 根据用于热交换的方法，流出的流体通过第一流体回路并且处理流体通过第二流体回路，使得流出物流体沿着膜的一侧通过，同时处理流体沿着 膜的另一面。 因此，热量在流出液体和膜上的处理流体之间交换。

公开(公告)号：US20110201988A1

公开(公告)日：2011-08-18

申请号：US13124258

申请日：2009-10-12

申请人： Mattias Holmer ,  Lennart Jönsson ,  Anders Wallenborg ,  Per Hansson

发明人： Mattias Holmer ,  Lennart Jönsson ,  Anders Wallenborg ,  Per Hansson

IPC分类号： A61M1/34 ,  A61M1/36

CPC分类号： A61M1/16 ,  A61M1/1601 ,  A61M2205/50

摘要： A blood treatment apparatus includes: a blood treatment unit, a pair of fluid pumps and a pair of blood pumps. The blood treatment unit is configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid. The fluid pumps are configured to pass blood treatment fluid through the blood treatment unit. The blood pumps are configured to extract untreated blood from a blood source, pass extracted blood through the blood treatment unit and deliver treated blood to a target vessel. Flow measurement device which determines at least one blood flow parameter reflecting an average flow in relation to the blood treatment unit during a well-defined period of operation of the apparatus, for example while completing one operation cycle. The at least one blood flow parameter is determined based on a difference between (i) a first amount of fresh blood treatment fluid received into the blood treatment unit, and (ii) a second amount of used blood treatment fluid emitted from the blood treatment unit during another well-defined period.

摘要翻译： 血液处理装置包括：血液处理单元，一对流体泵和一对血液泵。 血液处理单元被配置为接收未处理的血液和新鲜血液处理液，并且排出经处理的血液和使用的血液处理液。 流体泵配置成使血液处理液通过血液处理单元。 血泵被构造成从血液源中提取未经处理的血液，将提取的血液通过血液处理单元并将处理的血液输送到目标血管。 流量测量装置，例如在完成一个操作周期期间，确定在装置的操作的良好定义的周期期间反映相对于血液处理单元的平均流量的至少一个血流参数。 基于（i）接收到血液处理单元中的第一量的新鲜血液处理液和（ii）从血液处理单元发出的第二量的使用的血液处理液的差异来确定至少一个血流参数 在另一个明确的时期。

公开(公告)号：US20110034850A1

公开(公告)日：2011-02-10

申请号：US12937845

申请日：2009-04-14

申请人： Lennart Jönsson

发明人： Lennart Jönsson

IPC分类号： A61M1/00

CPC分类号： A61M1/30 ,  A61M1/1005 ,  A61M1/1006 ,  A61M1/1037 ,  A61M1/1086 ,  A61M1/16 ,  A61M1/302 ,  A61M1/303 ,  A61M1/306

摘要： A proposed blood treatment apparatus includes a blood treatment unit, at least one fluid pump and at least one blood pump. The fluid pumps are configured to pass blood treatment fluid through the blood treatment unit, while the blood pumps are configured to extract untreated blood from a blood source, e.g. a patient, pass the extracted blood through the blood treatment unit and deliver treated blood to a target vessel, e.g. likewise represented by a patient. Each blood pump includes a pumping chamber, which is separated into a first accumulation container and a second accumulation container by a flexible member. The flexible member is further movable within the pumping chamber so as to vary a volume relationship between the first and second accumulation containers. The second accumulation container is configured to receive an amount of blood treatment fluid to act on the flexible member and thus pump blood from the first accumulation container.

摘要翻译： 提出的血液处理装置包括血液处理单元，至少一个流体泵和至少一个血液泵。 流体泵构造成使血液处理流体通过血液处理单元，而血液泵构造成从血液源提取未处理的血液，例如血液。 将所提取的血液通过血液处理单元并将经处理的血液递送至靶容器，例如， 同样由患者代表。 每个血液泵包括泵送室，其通过柔性构件分离成第一积聚容器和第二积聚容器。 柔性构件可以在泵送室内进一步移动，以便改变第一和第二积聚容器之间的体积关系。 第二积聚容器被配置为接收一定量的血液处理流体以作用于柔性构件，从而从第一积聚容器泵送血液。

公开(公告)号：US07611493B2

公开(公告)日：2009-11-03

申请号：US10577353

申请日：2004-10-22

申请人： Lennart Jönsson

发明人： Lennart Jönsson

IPC分类号： A61M5/32

CPC分类号： A61M25/02 ,  A61M2025/0246 ,  A61M2025/026 ,  A61M2025/0266 ,  A61M2025/0273

摘要： A device for preventing axial movement of an elongated member (1) applied through the skin of a mammal at a puncturing position has a plaster (2) designed to cover the surface around the puncturing position and having at least an adhesive layer (4) for securing it to the skin as well as an opening (9) through the layer thereof for the passage of said elongated member therethrough. The device also has a clamp (8) secured to plaster and adapted to clamp around the elongated member when the elongated member is applied to the skin and the plaster is applied on the surface around said puncturing position. The clamp is thin and substantially flat.

摘要翻译： 用于防止在穿刺位置通过哺乳动物皮肤施加的细长构件（1）的轴向运动的装置具有设计成覆盖穿刺位置周围的表面的石膏（2），并且至少具有用于 将其固定到皮肤以及穿过其层的开口（9）以使所述细长构件通过其中。 该装置还具有固定到石膏上的夹具（8），并且当细长构件被施加到皮肤上时适于围绕细长构件夹紧，并且石膏被施加在围绕所述穿刺位置的表面上。 夹具薄而基本平坦。