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公开(公告)号：US08545427B2
公开(公告)日：2013-10-01
申请号：US13124316
申请日：2009-10-12
CPC分类号： A61M1/16 , A61M1/1601 , A61M2205/50
摘要： A blood treatment apparatus, including a blood treatment unit configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid, a pair of fluid pumps configured to pass blood treatment fluid through the blood treatment unit, a pair of blood pumps configured to extract untreated blood from a blood source, pass extracted blood through the blood treatment unit and deliver treated blood to a target vessel, each blood pump including a pump chamber and a flexible member separating the pumping chamber into a first blood accumulating container and a second working fluid accumulating container where the flexible member is configured to vary a volume relationship between the first and the second accumulation containers. A control unit and a measuring device are configured to emit a feedback signal indicative of the amount of working fluid received into, or discharged from at least one of the second accumulation containers whereby the pumped mass or volume of working fluid is determined by the control unit at an arbitrary position of the flexible member.
摘要翻译： 一种血液处理装置，包括：血液处理单元，其构造为接收未经处理的血液和新鲜血液处理液，并且排出经处理的血液和使用的血液处理流体;一对流体泵，被配置为使血液处理液通过所述血液处理单元， 被配置为从血液源提取未处理的血液的血液泵，将提取的血液通过血液处理单元并将处理的血液输送到目标血管，每个血液泵包括泵室和将泵送室分离成第一血液积聚的柔性构件 容器和第二工作流体积聚容器，其中柔性构件构造成改变第一和第二积聚容器之间的体积关系。 控制单元和测量装置被配置为发出指示接收到或从第二积聚容器中的至少一个排出的工作流体的量的反馈信号，由此泵送的质量或体积的工作流体由控制单元确定 在柔性构件的任意位置。
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公开(公告)号：US08485999B2
公开(公告)日：2013-07-16
申请号：US13124258
申请日：2009-10-12
CPC分类号： A61M1/16 , A61M1/1601 , A61M2205/50
摘要： A blood treatment apparatus includes: a blood treatment unit, a pair of fluid pumps and a pair of blood pumps. The blood treatment unit is configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid. The fluid pumps are configured to pass blood treatment fluid through the blood treatment unit. The blood pumps are configured to extract untreated blood from a blood source, pass extracted blood through the blood treatment unit and deliver treated blood to a target vessel. Flow measurement device which determines at least one blood flow parameter reflecting an average flow in relation to the blood treatment unit during a well-defined period of operation of the apparatus, for example while completing one operation cycle. The at least one blood flow parameter is determined based on a difference between (i) a first amount of fresh blood treatment fluid received into the blood treatment unit, and (ii) a second amount of used blood treatment fluid emitted from the blood treatment unit during another well-defined period.
摘要翻译： 血液处理装置包括：血液处理单元，一对流体泵和一对血液泵。 血液处理单元被配置为接收未处理的血液和新鲜血液处理液，并且排出经处理的血液和使用的血液处理液。 流体泵配置成使血液处理液通过血液处理单元。 血泵被构造成从血液源中提取未经处理的血液，将提取的血液通过血液处理单元并将处理的血液输送到目标血管。 流量测量装置，例如在完成一个操作周期期间，确定在装置的操作的良好定义的周期期间反映相对于血液处理单元的平均流量的至少一个血流参数。 基于（i）接收到血液处理单元中的第一量的新鲜血液处理液和（ii）从血液处理单元发出的第二量的使用的血液处理液的差异来确定至少一个血流参数 在另一个明确的时期。
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公开(公告)号：US20110201988A1
公开(公告)日：2011-08-18
申请号：US13124258
申请日：2009-10-12
CPC分类号： A61M1/16 , A61M1/1601 , A61M2205/50
摘要： A blood treatment apparatus includes: a blood treatment unit, a pair of fluid pumps and a pair of blood pumps. The blood treatment unit is configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid. The fluid pumps are configured to pass blood treatment fluid through the blood treatment unit. The blood pumps are configured to extract untreated blood from a blood source, pass extracted blood through the blood treatment unit and deliver treated blood to a target vessel. Flow measurement device which determines at least one blood flow parameter reflecting an average flow in relation to the blood treatment unit during a well-defined period of operation of the apparatus, for example while completing one operation cycle. The at least one blood flow parameter is determined based on a difference between (i) a first amount of fresh blood treatment fluid received into the blood treatment unit, and (ii) a second amount of used blood treatment fluid emitted from the blood treatment unit during another well-defined period.
摘要翻译： 血液处理装置包括：血液处理单元，一对流体泵和一对血液泵。 血液处理单元被配置为接收未处理的血液和新鲜血液处理液，并且排出经处理的血液和使用的血液处理液。 流体泵配置成使血液处理液通过血液处理单元。 血泵被构造成从血液源中提取未经处理的血液，将提取的血液通过血液处理单元并将处理的血液输送到目标血管。 流量测量装置，例如在完成一个操作周期期间，确定在装置的操作的良好定义的周期期间反映相对于血液处理单元的平均流量的至少一个血流参数。 基于（i）接收到血液处理单元中的第一量的新鲜血液处理液和（ii）从血液处理单元发出的第二量的使用的血液处理液的差异来确定至少一个血流参数 在另一个明确的时期。
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公开(公告)号：US20110201989A1
公开(公告)日：2011-08-18
申请号：US13124316
申请日：2009-10-12
CPC分类号： A61M1/16 , A61M1/1601 , A61M2205/50
摘要： A blood treatment apparatus, including a blood treatment unit configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid, a pair of fluid pumps configured to pass blood treatment fluid through the blood treatment unit, a pair of blood pumps configured to extract untreated blood from a blood source, pass extracted blood through the blood treatment unit and deliver treated blood to a target vessel, each blood pump including a pump chamber and a flexible member separating the pumping chamber into a first blood accumulating container and a second working fluid accumulating container where the flexible member is configured to vary a volume relationship between the first and the second accumulation containers. A control unit and a measuring device are configured to emit a feedback signal indicative of the amount of working fluid received into, or discharged from at least one of the second accumulation containers whereby the pumped mass or volume of working fluid is determined by the control unit at an arbitrary position of the flexible member.
摘要翻译： 一种血液处理装置，包括：血液处理单元，其构造为接收未经处理的血液和新鲜血液处理液，并且排出经处理的血液和使用的血液处理流体;一对流体泵，被配置为使血液处理液通过所述血液处理单元， 被配置为从血液源提取未处理的血液的血液泵，将提取的血液通过血液处理单元并将处理的血液输送到目标血管，每个血液泵包括泵室和将泵送室分离成第一血液积聚的柔性构件 容器和第二工作流体积聚容器，其中柔性构件构造成改变第一和第二积聚容器之间的体积关系。 控制单元和测量装置被配置为发出指示接收到或从第二积聚容器中的至少一个排出的工作流体的量的反馈信号，由此泵送的质量或体积的工作流体由控制单元确定 在柔性构件的任意位置。
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公开(公告)号：US20110024353A1
公开(公告)日：2011-02-03
申请号：US12937786
申请日：2009-04-14
申请人： Lennart Jönsson , Olof Jansson , Mattias Holmer , Jan Sternby , Anders Nilsson , Per Hansson
发明人： Lennart Jönsson , Olof Jansson , Mattias Holmer , Jan Sternby , Anders Nilsson , Per Hansson
IPC分类号： B01D61/32
CPC分类号： A61M1/16 , A61M1/1006 , A61M1/1037 , A61M1/1039 , A61M1/106 , A61M1/1065 , A61M1/1086 , A61M1/1601 , A61M1/34 , A61M1/3403 , A61M2205/3331 , A61M2205/3334 , A61M2205/50
摘要： A proposed blood treatment apparatus includes: a blood treatment unit, a pair of fluid pumps and a pair blood pumps. The blood treatment unit is configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid. The fluid pumps are configured to pass blood treatment fluid through the blood treatment unit. The blood pumps are configured to extract untreated blood from a blood source, pass extracted blood through the blood treatment unit and deliver treated blood to a target vessel. Additionally, the fluid pumps are configured to control the operation of the blood pumps via the blood treatment fluid. Moreover, a flow control device is configured to control a trans-membrane flow between the blood side and the a fluid side of the blood treatment unit. Hence, for instance ultrafiltration can be adjusted to a desired level in a very straightforward manner.
摘要翻译： 所提出的血液处理装置包括：血液处理单元，一对流体泵和一对血液泵。 血液处理单元被配置为接收未处理的血液和新鲜血液处理液，并且排出经处理的血液和使用的血液处理液。 流体泵配置成使血液处理液通过血液处理单元。 血泵被构造成从血液源中提取未经处理的血液，将提取的血液通过血液处理单元并将处理的血液输送到目标血管。 另外，流体泵配置成通过血液处理流体来控制血液泵的操作。 此外，流量控制装置被配置为控制血液侧和血液处理单元的流体侧之间的跨膜流动。 因此，例如超滤可以以非常直接的方式调整到期望的水平。
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公开(公告)号：US08580110B2
公开(公告)日：2013-11-12
申请号：US12937786
申请日：2009-04-14
申请人： Lennart Jönsson , Olof Jansson , Mattias Holmer , Jan Sternby , Anders Nilsson , Per Hansson
发明人： Lennart Jönsson , Olof Jansson , Mattias Holmer , Jan Sternby , Anders Nilsson , Per Hansson
CPC分类号： A61M1/16 , A61M1/1006 , A61M1/1037 , A61M1/1039 , A61M1/106 , A61M1/1065 , A61M1/1086 , A61M1/1601 , A61M1/34 , A61M1/3403 , A61M2205/3331 , A61M2205/3334 , A61M2205/50
摘要： A proposed blood treatment apparatus includes: a blood treatment unit, a pair of fluid pumps and a pair blood pumps. The blood treatment unit is configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid. The fluid pumps are configured to pass blood treatment fluid through the blood treatment unit. The blood pumps are configured to extract untreated blood from a blood source, pass extracted blood through the blood treatment unit and deliver treated blood to a target vessel. Additionally, the fluid pumps are configured to control the operation of the blood pumps via the blood treatment fluid. Moreover, a flow control device is configured to control a trans-membrane flow between the blood side and the a fluid side of the blood treatment unit. Hence, for instance ultrafiltration can be adjusted to a desired level in a very straightforward manner.
摘要翻译： 所提出的血液处理装置包括：血液处理单元，一对流体泵和一对血液泵。 血液处理单元被配置为接收未处理的血液和新鲜血液处理液，并且排出经处理的血液和使用的血液处理液。 流体泵配置成使血液处理液通过血液处理单元。 血泵被构造成从血液源中提取未经处理的血液，将提取的血液通过血液处理单元并将处理的血液输送到目标血管。 另外，流体泵配置成通过血液处理流体来控制血液泵的操作。 此外，流量控制装置被配置为控制血液侧和血液处理单元的流体侧之间的跨膜流动。 因此，例如超滤可以以非常直接的方式调整到期望的水平。
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公开(公告)号：US20110046535A1
公开(公告)日：2011-02-24
申请号：US12937858
申请日：2009-04-14
申请人： Lennart Jönsson , Olof Jansson , Mattias Holmer , se Nilsson
发明人： Lennart Jönsson , Olof Jansson , Mattias Holmer , se Nilsson
IPC分类号： A61M1/30
CPC分类号： A61M1/30 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1086 , A61M1/302 , A61M1/303 , A61M1/306 , A61M1/3626 , A61M2205/331
摘要： A proposed blood treatment apparatus includes: a blood treatment unit, at least one fluid pump and at least one blood pump. The blood treatment unit is configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid. The fluid pumps are configured to pass blood treatment fluid through the blood treatment unit. The blood pumps are configured to extract untreated blood from a blood source, pass extracted blood through the blood treatment unit and deliver treated blood to a target vessel. Additionally, at least one of the fluid pumps is configured to control the operation of at least one blood pump via the blood treatment fluid. Moreover, at least one of the blood pumps is integrated into a joint apparatus element, which includes the blood treatment unit. Thus, this blood pump and the unit may be mounted as well as be discarded jointly.
摘要翻译： 所提出的血液处理装置包括：血液处理单元，至少一个流体泵和至少一个血液泵。 血液处理单元被配置为接收未处理的血液和新鲜血液处理液，并且排出经处理的血液和使用的血液处理液。 流体泵配置成使血液处理液通过血液处理单元。 血泵被构造成从血液源中提取未经处理的血液，将提取的血液通过血液处理单元并将处理的血液输送到目标血管。 另外，流体泵中的至少一个配置成经由血液处理流体控制至少一个血液泵的操作。 此外，至少一个血泵被集成到包括血液处理单元的关节装置元件中。 因此，该血泵和单元可以被安装并被联合丢弃。
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公开(公告)号：US08652082B2
公开(公告)日：2014-02-18
申请号：US12937858
申请日：2009-04-14
申请人： Lennart Jönsson , Olof Jansson , Mattias Holmer , Eddie Nilsson
发明人： Lennart Jönsson , Olof Jansson , Mattias Holmer , Eddie Nilsson
IPC分类号： A61M37/00
CPC分类号： A61M1/30 , A61M1/1006 , A61M1/1037 , A61M1/106 , A61M1/1086 , A61M1/302 , A61M1/303 , A61M1/306 , A61M1/3626 , A61M2205/331
摘要： A proposed blood treatment apparatus includes: a blood treatment unit, at least one fluid pump and at least one blood pump. The blood treatment unit is configured to receive untreated blood and fresh blood treatment fluid, and emit treated blood and used blood treatment fluid. The fluid pumps are configured to pass blood treatment fluid through the blood treatment unit. The blood pumps are configured to extract untreated blood from a blood source, pass extracted blood through the blood treatment unit and deliver treated blood to a target vessel. Additionally, at least one of the fluid pumps is configured to control the operation of at least one blood pump via the blood treatment fluid. Moreover, at least one of the blood pumps is integrated into a joint apparatus element, which includes the blood treatment unit. Thus, this blood pump and the unit may be mounted as well as be discarded jointly.
摘要翻译： 所提出的血液处理装置包括：血液处理单元，至少一个流体泵和至少一个血液泵。 血液处理单元被配置为接收未处理的血液和新鲜血液处理液，并且排出经处理的血液和使用的血液处理液。 流体泵配置成使血液处理液通过血液处理单元。 血泵被构造成从血液源中提取未经处理的血液，将提取的血液通过血液处理单元并将处理的血液输送到目标血管。 另外，流体泵中的至少一个配置成经由血液处理流体控制至少一个血液泵的操作。 此外，至少一个血泵被集成到包括血液处理单元的关节装置元件中。 因此，该血泵和单元可以被安装并被联合丢弃。
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公开(公告)号：US06323182B1
公开(公告)日：2001-11-27
申请号：US09529213
申请日：2000-06-13
IPC分类号： A61K3170
CPC分类号： A61M1/1654 , A61K31/191 , A61K31/366 , A61K31/70 , A61M1/287 , A61K2300/00
摘要： Concentrates are disclosed for use in the preparation of infusion solutions preferably for use in dialysis including gluconic acid and glucose in amounts such that upon dilution with an aqueous solution in a ratio of at least about 1:150, the concentration of the gluconic acid is at least about 600 mmol/l and the concentration of the glucose is at least about 150 g/l.
摘要翻译： 浓缩物被公开用于制备优选用于透析（包括葡萄糖酸和葡萄糖）的输注溶液，其用量使得当用至少约1:150的比例用水溶液稀释时，葡萄糖酸的浓度在 至少约600mmol / l，葡萄糖浓度至少约为150g / l。
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10.发明授权公开(公告)号：US06296762B1
公开(公告)日：2001-10-02
申请号：US09570110
申请日：2000-05-12
IPC分类号： A61L200
CPC分类号： B01F1/00 , A61L2/0023 , A61L2/04 , A61M1/1656 , A61M1/1666 , A61M1/1668 , A61M1/167 , A61M1/1686 , A61M1/1688 , A61M1/169 , A61M2205/84 , B01F1/0038 , B01F3/1271 , B01F5/10 , B01F13/1013 , B01F13/1019 , B01F15/00824 , B01F15/0085 , B01F2015/062 , Y10T137/2499
摘要： Methods for the central preparation and distribution of a concentrate to a plurality of medical treatment devices are disclosed comprising supplying a stream of substantially only water to a central container which includes a single salt composition at least partially in solid form, producing a substantially saturated solution of the salt composition in the central container, and distributing the salt solution to a distribution conduit which includes a plurality of concentrate connectors whereby the salt solution can be distributed to the plurality of medical treatment devices. Methods for disinfecting this apparatus, the apparatus itself, and containers for use in the apparatus are also disclosed.
摘要翻译： 公开了将浓缩物中央制备和分配到多种医疗处理装置中的方法，其包括向中央容器供应基本上只有水的流，所述中央容器包括至少部分为固体形式的单一盐组合物，产生基本上饱和的 中央容器中的盐组成，并将盐溶液分配到分配管道，分配管道包括多个浓缩物连接器，由此盐溶液可以分配到多个医疗装置。 还公开了用于对该装置进行消毒的方法，装置本身和用于装置中的容器。
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