公开(公告)号：US08030354B2

公开(公告)日：2011-10-04

申请号：US12287036

申请日：2008-10-03

申请人： Sean P. Brown ,  Qiong Cao ,  Paul John Dransfield ,  Xiaohui Du ,  Zice Fu ,  Jonathan Houze ,  Xian Yun Jiao ,  Yong-Jae Kim ,  Todd J. Kohn ,  SuJen Lai ,  An-Rong Li ,  Daniel Lin ,  Jiwen Liu ,  Jian Luo ,  Julio C. Medina ,  Jeffrey D. Reagan ,  Vatee Pattaropong ,  Margrit Schwarz ,  Wang Shen ,  Yongli Su ,  Gayathri Swaminath ,  Marc Vimolratana ,  Yingcai Wang ,  Yumei Xiong ,  Li Yang ,  Ming Yu ,  Jie Zhang ,  Liusheng Zhu

发明人： Sean P. Brown ,  Qiong Cao ,  Paul John Dransfield ,  Xiaohui Du ,  Zice Fu ,  Jonathan Houze ,  Xian Yun Jiao ,  Yong-Jae Kim ,  Todd J. Kohn ,  SuJen Lai ,  An-Rong Li ,  Daniel Lin ,  Jiwen Liu ,  Jian Luo ,  Julio C. Medina ,  Jeffrey D. Reagan ,  Vatee Pattaropong ,  Margrit Schwarz ,  Wang Shen ,  Yongli Su ,  Gayathri Swaminath ,  Marc Vimolratana ,  Yingcai Wang ,  Yumei Xiong ,  Li Yang ,  Ming Yu ,  Jie Zhang ,  Liusheng Zhu

IPC分类号： A61K31/192 ,  C07C53/134

CPC分类号： C07C323/62 ,  C07C59/68 ,  C07C59/72 ,  C07C217/54 ,  C07C217/62 ,  C07C317/22 ,  C07C323/19 ,  C07C2601/02 ,  C07C2601/04 ,  C07C2601/08 ,  C07C2601/10 ,  C07C2601/14 ,  C07C2601/16 ,  C07C2601/18 ,  C07C2602/42 ,  C07C2603/74 ,  C07D213/64 ,  C07D309/12

摘要： The present invention provides compounds useful, for example, for treating metabolic disorders in a subject. Such compounds have the general formula I: where the definitions of the variables are provided herein. The present invention also provides compositions that include, and methods for using, the compounds in preparing medicaments and for treating metabolic disorders such as, for example, type II diabetes.

摘要翻译： 本发明提供了可用于例如治疗受试者的代谢紊乱的化合物。 这些化合物具有通式I：其中本文提供变量的定义。 本发明还提供了组合物，其包括化合物在制备药物和用于治疗代谢性疾病例如II型糖尿病中的使用方法。

公开(公告)号：US20110192779A1

公开(公告)日：2011-08-11

申请号：US13035645

申请日：2011-02-25

申请人： Matthew R. Linford ,  Robert C. Davis ,  Richard R. Vanfleet ,  David Scott Jensen ,  Li Yang

发明人： Matthew R. Linford ,  Robert C. Davis ,  Richard R. Vanfleet ,  David Scott Jensen ,  Li Yang

IPC分类号： B01D15/10 ,  B05D3/10 ,  C23C16/02 ,  C23F1/00 ,  B82Y30/00 ,  B82Y40/00

CPC分类号： B01J20/282 ,  B01J20/28007 ,  B01J20/286 ,  B82Y30/00 ,  B82Y40/00 ,  G01N30/92 ,  G01N30/93

摘要： In an embodiment, a method for manufacturing a thin layer chromatography (“TLC”) plate is disclosed. The method includes forming a layer of elongated nanostructures (e.g., carbon nanotubes), and at least partially coating the elongated nanostructures with a coating. The coating includes a stationary phase and/or precursor of a stationary phase for use in chromatography. The stationary phase may be functionalized with hydroxyl groups by exposure to acidified water vapor or immersion in a concentrated acid bath (e.g., HCl and methanol). At least a portion of the elongated nanostructures may be removed after being coated. Embodiments for TLC plates and related methods are also disclosed.

摘要翻译： 在一个实施方案中，公开了薄层色谱（“TLC”）板的制造方法。 该方法包括形成细长的纳米结构层（例如，碳纳米管），并且用涂层至少部分地涂覆细长的纳米结构。 涂层包括用于色谱法的固定相和/或固定相的前体。 固定相可以通过暴露于酸化水蒸气或浸入浓酸浴（例如HCl和甲醇）中的羟基官能化。 至少一部分细长的纳米结构可以在被涂覆之后被去除。 还公开了TLC板的实施例和相关方法。

公开(公告)号：US20110117446A1

公开(公告)日：2011-05-19

申请号：US12975477

申请日：2010-12-22

申请人： Brett Lucht ,  Li Yang ,  Mengqing Xu ,  Ang Xiao

发明人： Brett Lucht ,  Li Yang ,  Mengqing Xu ,  Ang Xiao

IPC分类号： H01M10/056

CPC分类号： H01M10/052 ,  H01M2/16 ,  H01M10/0525 ,  H01M10/056 ,  H01M10/0567 ,  H01M2300/0025 ,  H01M2300/0091 ,  Y02T10/7011

摘要： A lithium ion battery electrolyte for use in lithium ion batteries. The electrolyte includes LiPF6, LiBF4, LiB(C2O4)2, or a related salt dissolved in a mixture of organic carbonate, ether or ester solvents with low concentrations of oxidatively unstable additives such that the additives react with a surface of cathode particles to generate a passivation film which prevents oxidation of the electrolyte by the cathode. The additive is a polymerizable organic molecule selected from 2,3-dihydrofuran (2,3-DHF), 2,5-dihydrofuran (2,5-DHF), vinylene carbonate (VC), vinyltrimethoxysilane (VTMS), dimethyl vinylene cabonate (DMVC), and gamma-buyrolactone, or related unsaturated ethers, esters, or carbonates.

摘要翻译： 锂离子电池用锂离子电池。 电解质包括LiPF 6，LiBF 4，LiB（C 2 O 4）2或溶解在低浓度氧化不稳定的添加剂的有机碳酸酯，醚或酯溶剂的混合物中的相关盐，使得添加剂与阴极颗粒的表面反应产生 防止阴极氧化电解质的钝化膜。 添加剂是选自2,3-二氢呋喃（2,3-DHF），2,5-二氢呋喃（2,5-DHF），碳酸亚乙烯酯（VC），乙烯基三甲氧基硅烷（VTMS），二甲基亚乙烯基二 DMVC）和γ-丁内酯，或相关的不饱和醚，酯或碳酸酯。

公开(公告)号：US20080028079A1

公开(公告)日：2008-01-31

申请号：US11836949

申请日：2007-08-10

申请人： Li Yang ,  Lan Zou

发明人： Li Yang ,  Lan Zou

IPC分类号： G06F15/173 ,  G06F15/16

CPC分类号： H04L41/00 ,  H04L41/0226 ,  H04L69/24

摘要： A method for interface negotiation in a Network Management System (NMS) is disclosed. The method includes: sending by a sending party in an NMS Integration Reference Point (IRP) version information supported by the sending party to a receiving party in the NMS; and acquiring by the receiving party matching IRP version information between the sending party and the receiving party based on IRP version information supported by the receiving party and the IRP version information supported by the sending party. Another method for interface negotiation and apparatuses for interface negotiation in an NMS are disclosed as well. The matching IRP version information can match functional interface IRP, data definition IRP and NRM IRP of a managing unit with those of a managed unit, thus guaranteeing correct interaction between the managing unit and the managed unit, and greatly reducing the influence on the whole NMS after the network is partly updated.

摘要翻译： 公开了一种网管系统（NMS）中接口协商的方法。 该方法包括：发送方在发送方支持的NMS集成参考点（IRP）版本信息中发送给NMS中的接收方; 由接收方根据接收方支持的IRP版本信息和发送方支持的IRP版本信息，由发送方和接收方之间的IRP版本信息进行匹配。 还公开了接口协商的另一种方法和NMS中接口协商的装置。 匹配的IRP版本信息可以将管理单元的功能接口IRP，数据定义IRP和NRM IRP与被管理单元的IRP，NRM IRP进行匹配，从而保证管理单元与被管理单元之间的正确交互，大大降低了对整个网管的影响 网络部分更新后。

公开(公告)号：US20050154702A1

公开(公告)日：2005-07-14

申请号：US11016594

申请日：2004-12-17

申请人： Shi Liu ,  Li Yang

发明人： Shi Liu ,  Li Yang

IPC分类号： G06F7/00 ,  G06F17/00 ,  G06F17/20 ,  G06F17/30

CPC分类号： G06F17/30719 ,  G06F17/30011 ,  G06F17/30867 ,  Y10S707/917 ,  Y10S707/99931 ,  Y10S707/99942

摘要： Provides methods, apparatus, and systems for computer aided authoring. Included are: a method for browsing an electronic document, an apparatus for aided authoring, an electronic document browser, a method for retrieving an electronic document, a system for retrieving electronic documents, a method for subscribing and publishing an electronic document as well as a system for subscribing and publishing electronic documents. An example method for computer aided authoring includes: generating one or more topic summaries based on an electronic document while a writer is writing said electronic document, wherein the reliability of the topic summary is ensured by the writer; and saving said topic summary information in correspondence with said electronic document.

摘要翻译： 提供计算机辅助创作的方法，设备和系统。 包括：用于浏览电子文档的方法，用于辅助创作的装置，电子文档浏览器，用于检索电子文档的方法，用于检索电子文档的系统，用于订阅和发布电子文档的方法以及 订阅和发布电子文件的系统。 一种用于计算机辅助创作的示例方法包括：在作者写入所述电子文档时，基于电子文档生成一个或多个主题摘要，其中主题摘要的可靠性由作者确保; 并且与所述电子文档相对应地保存所述主题摘要信息。

公开(公告)号：US06203833B1

公开(公告)日：2001-03-20

申请号：US09505236

申请日：2000-02-16

申请人： Li Yang ,  Xiaoming Yang ,  Robert J. Petcavich ,  Lijun Mao

发明人： Li Yang ,  Xiaoming Yang ,  Robert J. Petcavich ,  Lijun Mao

IPC分类号： A23B7153

CPC分类号： A23B7/154 ,  A23B7/16

摘要： Fresh produce is preserved by coating the exterior surface of the produce with a coating composition comprising an aqueous solution of from about 0.5 to about 4 percent by weight of a cellulose derivative, preferably sodium carboxymethylcellulose, from about 0.05 to about 0.5 percent by weight of konjac, and from about 0.03 to about 0.1 percent by weight of surfactant, preferably dioctyl sodium sulfosuccinate. Optional constituents include antimicrobials, plasticizers and antifoaming agents. The coating composition is effective to control respiratory exchange, i.e., the passage of gases, particularly oxygen, ethylene, carbon dioxide and water vapor, into and out of the produce, thereby to control maturation and ripening of the produce.

摘要翻译： 通过用包含约0.5至约4重量％的纤维素衍生物，优选羧甲基纤维素钠，约0.05至约0.5重量％魔芋的水溶液的涂料组合物涂覆产品的外表面来保存新鲜产品 ，和约0.03至约0.1重量％的表面活性剂，优选二辛基磺基琥珀酸钠。 任选成分包括抗微生物剂，增塑剂和消泡剂。 涂料组合物有效地控制呼吸交换，即气体，特别是氧气，乙烯，二氧化碳和水蒸气进入和离开产物，从而控制产品的成熟和成熟。

公开(公告)号：US20240135256A1

公开(公告)日：2024-04-25

申请号：US18494330

申请日：2023-10-24

申请人： Jae-sun Seo ,  Jian Meng ,  Li Yang ,  Deliang Fan

发明人： Jae-sun Seo ,  Jian Meng ,  Li Yang ,  Deliang Fan

IPC分类号： G06N20/00

CPC分类号： G06N20/00

摘要： A method of training a machine learning algorithm comprises providing a set of input data, performing transforms on the input data to generate augmented data, to provide transformed base paths into machine learning algorithm encoders, segmenting the augmented data, calculating main base path outputs by applying a weighting to the segmented augmented data, calculating pruning masks from the input and augmented data to apply to the base paths of the machine learning algorithm encoders, the pruning masks having a binary value for each segment in the segmented augmented data, calculating sparse conditional path outputs by performing a computation on the segments of the segmented augmented data, and calculating a final output as a sum of the main base path outputs and the sparse conditional path outputs. A computer-implemented system for learning sparse features of a dataset is also disclosed.

公开(公告)号：USD960444S1

公开(公告)日：2022-08-09

申请号：US29778340

申请日：2021-04-13

申请人： Li Yang

设计人： Li Yang

公开(公告)号：US09988956B2

公开(公告)日：2018-06-05

申请号：US13978333

申请日：2012-01-13

申请人： Kamalesh K. Sirkar ,  Li Yang

发明人： Kamalesh K. Sirkar ,  Li Yang

IPC分类号： F01M11/03 ,  F01M1/10 ,  F16N39/06 ,  F01M13/04

CPC分类号： F01M11/03 ,  F01M1/10 ,  F01M2013/0477 ,  F16N39/06

摘要： An oil circulation system and method for continuously purifying engine oil including an engine operably connected to an oil reservoir, wherein at least one stream of oil is conveyed from the oil reservoir to the engine via a conduit, and circulated through the engine and conduit via engine operating pressure and/or one or more pumps, and at least one membrane unit positioned in a path of the oil stream such that oil containing dissolved/emulsified droplets of water is fed continuously through the membrane unit. A cross flow hollow fiber module adapted to be positioned in a system for continuously purifying engine oil, the hollow fiber module having a central feed distributor tube, hollow fiber membranes positioned around the central feed distributor tube, end caps with ports for receiving and emitting a flow of sweep air, and optionally a shell casing, wherein the central feed distributor tube includes openings sized and positioned to allow oil to flowing into the feed distributor tube to flow out radially.

公开(公告)号：US09290582B2

公开(公告)日：2016-03-22

申请号：US13699903

申请日：2011-05-26

申请人： Li Yang ,  Yuquan Wei

发明人： Li Yang ,  Yuquan Wei

IPC分类号： C07K19/00 ,  C07K14/47 ,  C07K14/705 ,  A61K38/00 ,  A61K48/00 ,  A61K31/7088

CPC分类号： C07K19/00 ,  A61K31/7088 ,  A61K38/00 ,  A61K48/005 ,  C07K14/4703 ,  C07K14/70578 ,  C07K2319/00 ,  C07K2319/30

摘要： The present invention relates to the field of genetic engineering drugs, particularly to a novel B cell activating factor (BAFF) antagonist and use thereof. The technical problem to be solved by the invention is to find a new and effective selection for the prevention and treatment of autoimmune diseases. The B cell activating factor receptor antagonist is mainly obtained by the fusion of the domain 2 binding BAFF in TACI receptor and the domain binding BAFF in Br3 receptor, and it also can be fused with a Fc segment of IgG1 to obtain a new fusion protein molecule. Experiments indicate that said new fusion protein molecule has the function of BAFF antagonist, which can treat the autoimmune diseases, and supply a new and effective selection for the prevention and treatment of the autoimmune diseases.

摘要翻译： 本发明涉及遗传工程药物领域，特别涉及一种新型B细胞激活因子（BAFF）拮抗剂及其应用。 本发明要解决的技术问题是找到一种新的有效的预防和治疗自身免疫性疾病的选择。 B细胞激活因子受体拮抗剂主要通过融合TACI受体中的结构域2结合BAFF和Br3受体结合BAFF的结构域而获得，并且还可以与IgG1的Fc区融合以获得新的融合蛋白分子 。 实验表明，所述新型融合蛋白分子具有BAFF拮抗剂的功能，可以治疗自身免疫性疾病，为预防和治疗自身免疫性疾病提供新的有效选择。