公开(公告)号：US20060276832A1

公开(公告)日：2006-12-07

申请号：US11395700

申请日：2006-03-31

申请人： Keith Balgobin ,  Donald Jones ,  Vladimir Mitelberg ,  John Thinnes

发明人： Keith Balgobin ,  Donald Jones ,  Vladimir Mitelberg ,  John Thinnes

IPC分类号： A61M29/00

CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/12154 ,  A61B2017/00477 ,  A61B2017/00862 ,  A61B2017/12054

摘要： A medical device for placing an embolic device at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member slidably disposed within the lumen of the catheter. An embolic device is retained within the delivery catheter by a mechanical interlocking mechanism which includes an engagement member attached to the distal end of the pusher member and extends through a retaining ring at the proximal end of the embolic device. A detachment member extends through an aperture at the distal end of the engagement member thereby locking the embolic device onto the pusher member. A kicker member, which takes the form of a helical spring, extends from the distal end of the pusher member and is biased so as to lift the retaining ring off of the engagement member to ensure the release of the embolic device when the detachment member is withdrawn from the aperture of the engagement member.

摘要翻译： 一种用于将栓塞装置放置在主体容器内的预定位置处的医疗装置，包括输送导管和可滑动地设置在导管内腔内的柔性推动器构件。 栓塞装置通过机械互锁机构保持在输送导管内，该机械互锁机构包括附接到推动器构件的远端的接合构件并延伸穿过栓塞装置的近端处的保持环。 分离构件延伸穿过接合构件的远端处的孔，从而将栓塞装置锁定到推动器构件上。 采取螺旋弹簧形式的起动器构件从推动器构件的远端延伸并且被偏置以便将保持环从接合构件提升离开以确保当分离构件是释放构件时释放栓塞装置 从接合构件的孔中取出。

公开(公告)号：US20060276830A1

公开(公告)日：2006-12-07

申请号：US11302730

申请日：2005-12-14

申请人： Keith Balgobin ,  Donald Jones ,  Vladimir Mitelberg ,  Darren Sherman ,  John Thinnes

发明人： Keith Balgobin ,  Donald Jones ,  Vladimir Mitelberg ,  Darren Sherman ,  John Thinnes

IPC分类号： A61M29/00

CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/12154 ,  A61B2017/00477 ,  A61B2017/12054

摘要： A medical device for placing an embolic device at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member slidably disposed within the lumen of the catheter. An embolic device is retained within the delivery catheter by a mechanical interlocking mechanism which includes an engagement member attached to the distal end of the pusher member and extends through a retaining ring at the proximal end of the embolic device. A detachment member extends through an aperture at the distal end of the engagement member thereby locking the embolic device onto the pusher member. A kicker member extends from the distal end of the pusher member and is biased so as to lift the retaining ring off of the engagement member to ensure the release of the embolic device when the detachment member is withdrawn from the aperture of the engagement member.

摘要翻译： 一种用于将栓塞装置放置在主体容器内的预定位置处的医疗装置，包括输送导管和可滑动地设置在导管内腔内的柔性推动器构件。 栓塞装置通过机械互锁机构保持在输送导管内，该机械互锁机构包括附接到推动器构件的远端的接合构件并延伸穿过栓塞装置的近端处的保持环。 分离构件延伸穿过接合构件的远端处的孔，从而将栓塞装置锁定到推动器构件上。 推动器构件从推动器构件的远端延伸并且被偏压以便将保持环从接合构件提起，以确保当分离构件从接合构件的孔中取出时栓塞装置的释放。

公开(公告)号：US20060276828A1

公开(公告)日：2006-12-07

申请号：US11301664

申请日：2005-12-13

申请人： Keith Balgobin ,  Donald Jones ,  Vladimir Mitelberg ,  Darren Sherman ,  John Thinnes

发明人： Keith Balgobin ,  Donald Jones ,  Vladimir Mitelberg ,  Darren Sherman ,  John Thinnes

IPC分类号： A61M29/00

CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/12154 ,  A61B2017/00477 ,  A61B2017/00867 ,  A61B2017/12054

摘要： A medical device for placing an embolic device, such as an embolic coil at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member slidably disposed within the lumen of the catheter. An embolic device is retained within the delivery catheter by a mechanical interlocking mechanism which includes a deflectable engagement member attached to the distal end of the pusher member and extends through a retaining ring at the proximal end of the embolic device. A detachment member extends through an aperture at the distal end of the engagement member thereby locking the embolic device onto the pusher member. When the detachment member is withdrawn from the aperture of the engagement member the engagement member deflects to release the embolic device.

摘要翻译： 一种用于将栓塞装置（例如栓塞线圈）放置在主体容器内的预定位置处的医疗装置，包括输送导管和可滑动地设置在导管内腔内的柔性推动器构件。 栓塞装置通过机械互锁机构保持在输送导管内，该机械联锁机构包括附接到推动器构件的远端的可偏转接合构件，并且延伸穿过栓塞装置的近端处的保持环。 分离构件延伸穿过接合构件的远端处的孔，从而将栓塞装置锁定到推动器构件上。 当分离构件从接合构件的孔中取出时，接合构件偏转以释放栓塞装置。

公开(公告)号：US20060276825A1

公开(公告)日：2006-12-07

申请号：US11171679

申请日：2005-06-30

申请人： Vladimir Mitelberg ,  Donald Jones ,  Juan Lorenzo

发明人： Vladimir Mitelberg ,  Donald Jones ,  Juan Lorenzo

IPC分类号： A61M29/00

CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/1215 ,  A61B17/12154 ,  A61B2017/00477 ,  A61B2017/00867 ,  A61B2017/12054

摘要： A medical device for placing an embolic device at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member having a lumen therethrough and being slidably disposed within the lumen of the catheter. A stretch resistant embolic device is retained within the delivery catheter by a mechanical interlocking mechanism which includes an engagement member which is attached to the distal end of the pusher member and extends through a retaining ring at the proximal end of the embolic device. A detachment member extends through an aperture at the distal end of the engagement member thereby locking the embolic device onto the pusher member. The engagement member engages a retaining ring on the embolic device. When the embolic device is advanced to the predetermined site within the vessel, the detachment member is withdrawn from the aperture to thereby release the embolic device at the treatment site.

摘要翻译： 一种用于将栓塞装置放置在身体的容器内的预定位置处的医疗装置，包括输送导管和具有通过其的腔的柔性推动器构件，并且可滑动地设置在导管的腔内。 弹性阻塞栓塞装置通过机械互锁机构保持在输送导管内，该机械互锁机构包括接合构件，该接合构件附接到推动器构件的远端并延伸穿过栓塞装置的近端处的保持环。 分离构件延伸穿过接合构件的远端处的孔，从而将栓塞装置锁定到推动器构件上。 接合构件接合栓塞装置上的保持环。 当栓塞装置前进到血管内的预定位置时，分离构件从孔中取出，从而在治疗部位释放栓塞装置。

公开(公告)号：US20060058834A1

公开(公告)日：2006-03-16

申请号：US11171560

申请日：2005-11-18

申请人： Hiep Do ,  Richard Davis ,  Donald Jones ,  Juan Lorenzo ,  Vladimir Mitelberg ,  Darren Sherman ,  Murty Vyakarnam

发明人： Hiep Do ,  Richard Davis ,  Donald Jones ,  Juan Lorenzo ,  Vladimir Mitelberg ,  Darren Sherman ,  Murty Vyakarnam

IPC分类号： A61M29/00

CPC分类号： A61B17/12022 ,  A61B17/12145 ,  A61B17/1215 ,  A61B17/12163 ,  A61B17/12181 ,  A61B17/1219 ,  A61B2017/0053 ,  A61B2017/1205 ,  A61L31/10 ,  A61L31/146 ,  A61L2430/36 ,  C08L67/04

摘要： The present invention relates to a medical device for placement at a predetermined location within a passageway of the human body, and more particularly, relates to a flexible embolization device which may be delivered by a catheter to a pre-selected position within a blood vessel to thereby embolize a blood vessel or a blood vessel defect, such as an aneurysm or fistula. Specifically, the embolization device comprises an elongated coil having a lumen, the coil and lumen being at least partially embedded in an elongated foam member comprising, in some embodiments, a flexible, biodegradable, water insoluble, open, interconnecting-cell foam material having embolic characteristics, and capable of allowing cell proliferation into the open cell foam interior.

摘要翻译： 本发明涉及一种用于放置在人体通道内的预定位置处的医疗装置，更具体地涉及一种柔性栓塞装置，其可以由导管递送到血管内的预先选定的位置， 从而栓塞血管或血管缺损，例如动脉瘤或瘘。 具体地，栓塞装置包括具有内腔的细长线圈，线圈和内腔至少部分地嵌入细长的泡沫构件，其在一些实施例中包括具有栓塞的柔性，可生物降解的水不溶性，开放的互连泡沫材料 特征，并且能够允许细胞增殖进入开孔泡沫内部。

公开(公告)号：US20060025845A1

公开(公告)日：2006-02-02

申请号：US11208292

申请日：2005-08-19

申请人： Angeli Escamilla ,  Donald Jones ,  Vladimir Mitelberg

发明人： Angeli Escamilla ,  Donald Jones ,  Vladimir Mitelberg

IPC分类号： A61F2/06

CPC分类号： A61F2/91 ,  A61B17/12022 ,  A61B17/12118 ,  A61B17/1214 ,  A61B2017/1205 ,  A61F2/915 ,  A61F2/95 ,  A61F2/966 ,  A61F2002/823 ,  A61F2002/8486 ,  A61F2002/91533 ,  A61F2002/91541 ,  A61F2002/9155 ,  A61F2002/91558 ,  A61F2002/9665 ,  A61F2250/0098

摘要： An expandable stent and delivery system therefor is provided for treating vascular diseases such as partially occluded blood vessels and aneurysms. The delivery system includes proximal, intermediate and distal cylindrical members disposed about an elongated core member. The proximal, intermediate, and distal cylindrical members are spaced apart such that first and second gaps are formed. The expandable stent includes anchor members which are formed by winding a radiopaque coil onto a threaded portion of a strut member of the expandable stent. The expandable stent is mounted on the intermediate cylindrical member with the anchor members disposed within the gaps between the cylindrical members. A deployment catheter is used to compress and constrain the stent about the intermediate cylindrical member to thereby interlock the stent onto the core member.

摘要翻译： 提供了一种用于治疗血管疾病例如部分闭塞的血管和动脉瘤的可扩张支架及其输送系统。 递送系统包括围绕细长的核心构件设置的近端，中间和远端圆柱形构件。 近端，中间和远端圆柱形构件间隔开，使得形成第一和第二间隙。 可扩张支架包括锚定构件，其通过将不透射线的线圈卷绕到可扩张支架的支柱构件的螺纹部分上而形成。 可扩张支架安装在中间圆柱形构件上，锚定构件设置在圆柱形构件之间的间隙内。 使用展开导管来压缩和限制围绕中间圆柱形构件的支架，从而将支架联锁到芯构件上。

公开(公告)号：US20080039930A1

公开(公告)日：2008-02-14

申请号：US11903463

申请日：2007-09-21

申请人： Donald Jones ,  Vladimir Mitelberg

发明人： Donald Jones ,  Vladimir Mitelberg

IPC分类号： A61F2/06

CPC分类号： A61B17/12022 ,  A61B17/12118 ,  A61B2017/1205 ,  A61F2/91 ,  A61F2/95 ,  A61F2002/823 ,  A61F2230/0008

摘要： A self-expanding aneurysm cover device which takes the form of an outwardly biased cylindrical skeletal frame in which the proximal end of the cylindrical skeletal frame forms a loop which extends at an oblique angle to the axis of the cylindrical skeletal frame. A positioning tab extends from the proximal end of the skeletal frame which when pulled causes the cylindrical skeletal frame to collapse to a reduced diameter for removal of the device from a vessel.

摘要翻译： 一种自膨胀动脉瘤覆盖装置，其采取向外偏压的圆柱形骨架框架的形式，其中圆柱形骨架框架的近端形成以与圆柱形骨架框架的轴线成倾斜角度延伸的环。 定位突片从骨架框架的近端延伸，当被拉动时，该突出部分使得圆柱形骨架框架塌缩到减小的直径，以将装置从容器中取出。

公开(公告)号：US20070203518A1

公开(公告)日：2007-08-30

申请号：US11363775

申请日：2006-02-28

申请人： Donald Jones ,  Vladimir Mitelberg

发明人： Donald Jones ,  Vladimir Mitelberg

IPC分类号： A61M29/00

CPC分类号： A61B17/12022 ,  A61B17/1214 ,  A61B2017/00411 ,  A61B2017/00862 ,  A61B2017/12072 ,  A61B2017/12077

摘要： The disclosure describes apparatuses and methods for the luminal delivery of therapeutic devices. The apparatus includes a decoupling assembly comprising a retention element, a energy-responsive element and a thermally sensitive element. The application of heat to the thermally sensitive element alters its configuration such that it no longer maintains the retention element in engagement with the therapeutic device, releasing the therapeutic device.

摘要翻译： 本公开描述了治疗装置的腔内递送的装置和方法。 该装置包括一个去耦组件，它包括保持元件，能量响应元件和热敏元件。 将热应用于热敏元件改变其构造，使得其不再保持保持元件与治疗装置接合，释放治疗装置。

公开(公告)号：US20060276824A1

公开(公告)日：2006-12-07

申请号：US11143052

申请日：2005-06-02

申请人： Vladimir Mitelberg ,  Donald Jones ,  Juan Lorenzo

发明人： Vladimir Mitelberg ,  Donald Jones ,  Juan Lorenzo

IPC分类号： A61M29/00

CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/12154 ,  A61B2017/1205 ,  A61B2017/12054

摘要： A medical device for placing an embolic device at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member having a lumen therethrough and being slidably disposed within the lumen of the catheter. A stretch resistant embolic device is retained within the delivery catheter by a mechanical interlocking mechanism which includes an engagement member which is attached to the distal end of the pusher member and extends through a retaining ring at the proximal end of the embolic device. A detachment member extends through an aperture at the distal end of the engagement member thereby locking the embolic device onto the pusher member. The engagement member engages a retaining ring on the embolic device. When the embolic device is advanced to the predetermined site within the vessel, the detachment member is withdrawn from the aperture to thereby release the embolic device at the treatment site.

公开(公告)号：US20060276823A1

公开(公告)日：2006-12-07

申请号：US11143051

申请日：2005-06-02

申请人： Vladimir Mitelberg ,  Donald Jones ,  Juan Lorenzo

发明人： Vladimir Mitelberg ,  Donald Jones ,  Juan Lorenzo

IPC分类号： A61M29/00

CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/1214 ,  A61B2017/00477 ,  A61B2017/12054

摘要： A medical device for placing an embolic device at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member having a lumen therethrough and being slidably disposed within the lumen of the catheter. An embolic device is retained within the delivery catheter by a mechanical interlocking mechanism which includes an engagement member which is attached to the distal end of the pusher member and extends through a retaining ring at the proximal end of the embolic device. A detachment member extends through an aperture at the distal end of the engagement member thereby locking the embolic device onto the pusher member. When the embolic device is advanced to the predetermined site within the vessel, the detachment member is withdrawn from the aperture to thereby release the embolic device at the treatment site.

摘要翻译： 一种用于将栓塞装置放置在身体的容器内的预定位置处的医疗装置，包括输送导管和具有通过其的腔的柔性推动器构件，并且可滑动地设置在导管的腔内。 栓塞装置通过机械互锁机构保持在输送导管内，该联动机构包括接合构件，该接合构件附接到推动器构件的远端并延伸穿过栓塞装置的近端处的保持环。 分离构件延伸穿过接合构件的远端处的孔，从而将栓塞装置锁定到推动器构件上。 当栓塞装置前进到血管内的预定位置时，分离构件从孔中取出，从而在治疗部位释放栓塞装置。