公开(公告)号：US6114431A

公开(公告)日：2000-09-05

申请号：US965970

申请日：1997-11-07

申请人： Victor Lee ,  Ed Wykoff ,  Mark A. Crawford

发明人： Victor Lee ,  Ed Wykoff ,  Mark A. Crawford

IPC分类号： A01G7/00 ,  A01G9/02 ,  C08K3/08 ,  C08K3/22 ,  C08K3/26 ,  C08K3/30 ,  C08L1/08 ,  C08L3/02 ,  C08L23/04 ,  C08L67/04 ,  C08L97/00 ,  C08L101/14 ,  C08J5/10 ,  C08K3/10 ,  C08L33/06

CPC分类号： C08K3/26 ,  C08K3/22 ,  C08K3/30 ,  C08L67/04

摘要： A plastic composition having incorporated copper is provided in accordance with the invention. The plastic material can be processed at low temperatures, readily absorbs water, and has good film forming properties. In particular, the plastic material is a polycaprolactone and the copper is derived from copper hydroxide and/or copper carbonate. The plastic material is useful for forming plant containers that promote a branched root structure.

摘要翻译： 根据本发明提供了掺入铜的塑料组合物。 塑料材料可在低温下加工，容易吸水，成膜性能好。 特别地，塑料材料是聚己内酯，铜源由氢氧化铜和/或碳酸铜制成。 塑料材料可用于形成促进枝根结构的植物容器。

公开(公告)号：US5117981A

公开(公告)日：1992-06-02

申请号：US681213

申请日：1991-04-05

申请人： Mark A. Crawford ,  T. Andrew Guhl ,  J. Robert Stanley

发明人： Mark A. Crawford ,  T. Andrew Guhl ,  J. Robert Stanley

IPC分类号： A61B19/02 ,  A61B19/04 ,  E06B9/44

CPC分类号： E06B9/44 ,  A61B42/40 ,  A61B50/30 ,  E06B2009/407 ,  E06B2009/445

摘要： A kit comprises a tray with a well for a tourniquet, a dressing to use with a medical device inserted into a blood vessel. An antimicrobial treatment in the well disinfects an area of skin through which the medical device punctures the vessel. A pair of juxtaposed gloves with the finger ends, the hand parts and the cuff portions against one another are rolled up along their longitude from their fingers to their cuffs driving out air entrapped within the gloves. The process of rolling from the fingers to the cuffs leaves the cuffs of each glove at the periphery of the rolled generally cylindrical gloves for access to the inside of each when donning. A method for rolling gloves into a relatively cylindrical package, includes setting the gloves side by side with the finger ends, the hand parts, and the wrist or cuff portions juxtaposed. The finger portions are gathered into an axial bundle and rolled from the finger ends toward the palm or back hand parts driving out air within the gloves. Rolling along the elongate longitude of the gloves to the cuff or wrist portions, drives air from the cuffs and provides a cylindrical package. The method may include the added step of binding the rolled gloves with a band or tape. The compact package of gloves rolled up together along their longitude has binding about the middle to hold the rolled glove pair together so they are diametrically smaller than they are wide.

摘要翻译： 套件包括具有用于止血带的托盘的托盘，用于与插入血管的医疗装置一起使用的敷料。 井中的抗菌处理消毒了医疗器械穿过血管的皮肤区域。 手指末端的一对并置的手套，彼此相对的手部部分和袖口部分从他们的手指向他们的手指卷起到袖口上，从而驱赶夹在手套内的空气。 从手指滚动到袖口的过程在滚动的大致圆柱形手套的外围留下每个手套的袖口，以便在穿戴时进入每个手套的内部。 将手套滚动到相对圆筒形的包装中的方法包括将手指并排配置，手指部分和手腕或袖带部分并置。 手指部分聚集成轴向束并从手指端朝着手掌或后手部分滚动，从而驱除手套内的空气。 沿着手套的细长经度滚动到袖口或腕部，驱动袖带上的空气并提供圆柱形包装。 该方法可以包括用滚筒或胶带捆绑滚动的手套的附加步骤。 沿着经度一起卷起的手套的紧凑包装具有中间的约束力，将卷起的手套对保持在一起，因此它们比其宽度更小。

公开(公告)号：US4894052A

公开(公告)日：1990-01-16

申请号：US234664

申请日：1988-08-22

申请人： Mark A. Crawford

发明人： Mark A. Crawford

IPC分类号： A61M25/06

CPC分类号： A61M25/0693

摘要： A flash cavity is positioned between the inside of a translucent over the needle catheter and a needle for providing flash detection. The needle bore is connected to the cavity by an access port positioned near the location where the tip of the catheter sealably engages the needle. The needle bore is flow restricted between the access port and a hub for manipulating the needle. In one form of the introducer, a guide wire positioned by a syringe plunger carried for movement in a syringe barrel, is used to advance the catheter into the vessel. The syringe barrel restricts passage of liquid blood, but vents gases. In another arrangement of the introducer, a porous vent plug cooperates with the end of the needle and the catheter adapter to restrict blood flow through the needle bore and to prevent escape of blood while permitting escape of gases. A method of using the flash cavity for the early detection of blood provides for the proper placement in a blood vessel of the tip of the needle and catheter carried therewith wherein the needle has a restricted needle bore and a needle hub prevents escape of blood.

摘要翻译： 闪光腔位于针导管上半透明的内部和用于提供闪光检测的针之间。 针孔通过位于导管的尖端可密封地接合针的位置附近的进入端口连接到空腔。 针孔在进出口和用于操作针的轮毂之间流动受限。 在导引器的一种形式中，使用由用于在注射器筒中运动的注射器柱塞定位的导丝线将导管推进到容器中。 注射器筒限制液体血液的通过，但是排放气体。 在导引器的另一布置中，多孔通气塞与针的端部和导管适配器配合，以限制血液穿过针孔的流动并防止血液逸出，同时允许气体逸出。 使用闪光腔用于早期检测血液的方法提供了适当的放置在针头和导管的血管中，其中针具有限制的针孔，并且针毂防止血液逸出。

公开(公告)号：US06471976B1

公开(公告)日：2002-10-29

申请号：US08387397

申请日：1995-02-13

申请人： Evelyn J. Taylor ,  Mark A. Crawford

发明人： Evelyn J. Taylor ,  Mark A. Crawford

IPC分类号： A61K3144

CPC分类号： A01N37/04 ,  A01N59/20 ,  A01N2300/00

摘要： There is disclosed an improved copper complex bactericide/fungicide and a method of making and using the same. The improved bactericide/fungicide is prepared by forming an aqueous solution of a partially neutralized, water-soluble polycarboxylic acid having a molecular weight of between approximately 1,000 and 300,000 and a pH of between approximately 3 and 9. To this aqueous solution is added a copper-containing compound which when combined with said aqueous solution releases copper (II) ions which will form a water-soluble complex with said partially neutralized polycarboxylic acid. The water-soluble copper complex is applied to plants to prevent or inhibit bacterial and fungal disease growth thereon.

摘要翻译： 公开了一种改进的铜络合物杀菌剂/杀菌剂及其制备和使用方法。 改进的杀菌剂/杀真菌剂是通过形成分子量在大约1000和300,000之间的部分中和的水溶性多元羧酸的水溶液和约3和9之间的pH来制备的。向该水溶液中加入铜 当与所述水溶液组合时，会释放与所述部分中和的多元羧酸形成水溶性络合物的铜（II）离子。 将水溶性铜络合物施用于植物以防止或抑制其上的细菌和真菌疾病生长。

公开(公告)号：US06273871B1

公开(公告)日：2001-08-14

申请号：US09456958

申请日：1999-12-07

申请人： Bryan G. Davis ,  Mark A. Crawford ,  Glade H. Howell

发明人： Bryan G. Davis ,  Mark A. Crawford ,  Glade H. Howell

IPC分类号： A61M5178

CPC分类号： A61M25/0637 ,  A61M25/0606

摘要： A catheter introducer is disclosed having a splittable introducer and an introducer needle. The splittable introducer includes a pair of wings and a tray with an open top extending from the proximal end of the introducer cannula between the wings to lead the distal end of a long, thin and flexible medical device into the open proximal end of the splittable introducer cannula.

摘要翻译： 公开了一种导管导引器，其具有可分开的引导器和引导器针。 可拆卸引导器包括一对翼和具有开口顶部的托盘，其从引导器套管的近端延伸到翼之间，以将长而薄且柔性的医疗装置的远端引导到可拆卸引导器的开口近端 套管。

公开(公告)号：US5558651A

公开(公告)日：1996-09-24

申请号：US364071

申请日：1994-12-27

申请人： Mark A. Crawford ,  Timothy J. Erskine ,  Gerald H. Peterson

发明人： Mark A. Crawford ,  Timothy J. Erskine ,  Gerald H. Peterson

IPC分类号： A61M25/06 ,  A61M5/00

CPC分类号： A61M25/0618 ,  A61M2005/325 ,  A61M5/3273

摘要： A needle and a cover with a needle having an elongate shank and a tip with a sharpened point. The cover is coaxially associated with the elongate shank for movement therealong toward the tip and includes a part for extending beyond the sharpened point when the cover is positioned near the tip. A lock associated with the needle and cover cooperates and holds the cover to prevent axially movement relative to the needle tip after positioning the cover near the tip. The needle and cover may be a part of a catheter assembly having a catheter and an adapter connected to one another for fluid communication and carried coaxially about the needle and hub. The catheter has a bore therethrough sized to surround the elongate shank for movement therewith during insertion and therealong during placement. A retaining means on the adapter and on the cover releasably attach the cover to the adapter while on the elongate shank of the needle allowing the needle and cover to be disengaged from the catheter and adapter after placement.

摘要翻译： 针和具有针的盖具有细长的柄和具有锐化点的尖端。 盖与细长柄同轴地关联，用于朝着顶端移动，并且当盖位于尖端附近时包括用于延伸超过磨尖点的部分。 与针头和盖子相关联的锁定件将盖子定位在尖端附近并配合并保持盖子以防止相对于针头的轴向运动。 针和盖可以是具有导管和适配器的导管组件的一部分，该适配器彼此连接用于流体连通并且围绕针和毂共轴承载。 导管具有穿过其中的孔，其尺寸设置成围绕细长柄以在插入期间随着其移动，并且在放置期间沿着其延伸。 适配器和盖子上的保持装置在针的细长柄上可释放地将盖子附接到适配器，允许针和盖在放置之后与导管和适配器脱离接合。

公开(公告)号：US5535771A

公开(公告)日：1996-07-16

申请号：US288171

申请日：1994-08-10

申请人： E. Robert Purdy ,  Mark A. Crawford ,  Timothy J. Erskine ,  Gerald H. Peterson

发明人： E. Robert Purdy ,  Mark A. Crawford ,  Timothy J. Erskine ,  Gerald H. Peterson

IPC分类号： A61M39/02 ,  A61M39/00 ,  A61M39/06 ,  A61M39/26 ,  F16L37/28

CPC分类号： A61M39/0606 ,  A61M39/26 ,  Y10S604/905 ,  Y10T137/0402

摘要： A valved adapter for a medical access device includes a body with a longitudinal axis. The body has a proximal first end, a distal second end and a passageway therethrough which has an inside surface. The passageway has a chamber defined by a proximal shoulder and a segmented distal shoulder both projecting inwardly from the surface of the passageway. The chamber is located intermediate the first end and second end of the body. The adapter includes a valve contained within the chamber for selectively obstructing and allowing fluid flow through the passageway. The valve includes an elongate resilient member with an axis substantially coaxial to the longitudinal axis of the body having a proximal end and a distal end. The elongate resilient member is axially compressed between the distal shoulder and the proximal shoulder, the compression biasing the valve to a normally closed position. The proximal end of the resilient member forms a substantially fluid tight seal with the proximal shoulder which obstructs fluid flow through the passageway. The adapter further includes a pusher for selectively further axially compressing the resilient member so that the proximal end of the adapter no longer forms a fluid tight seal with the proximal shoulder thereby allowing fluid flow through the passageway. The adapter includes fittings for attaching the adapter to a medical access device and for attaching fluid delivery devices to the adapter.

摘要翻译： 用于医疗进入装置的阀式适配器包括具有纵向轴线的主体。 主体具有近端第一端，远端第二端和穿过其的通道，其具有内表面。 通道具有由近侧肩部和分段的远侧肩部限定的室，两个远侧肩部从通道的表面向内突出。 腔室位于身体的第一端和第二端之间。 适配器包括容纳在腔室内的阀，用于选择性地阻塞和允许流体流过通道。 阀包括细长的弹性构件，其具有基本上与主体的纵向轴线同轴的轴线，该轴线具有近端和远端。 细长的弹性构件在远端肩部和近侧肩部之间被轴向压缩，压缩将阀门偏压到常闭位置。 弹性构件的近端形成与近侧肩部基本上流体密封的密封，其阻止流体流过通道。 适配器还包括用于选择性地进一步轴向压缩弹性构件的推动器，使得适配器的近端不再与近侧肩部形成流体密封，从而允许流体流过通道。 适配器包括用于将适配器附接到医疗接入装置并用于将流体输送装置附接到适配器的配件。

公开(公告)号：US5298253A

公开(公告)日：1994-03-29

申请号：US928148

申请日：1992-08-11

申请人： James H. LeFiles ,  Evelyn J. Taylor ,  Mark A. Crawford

发明人： James H. LeFiles ,  Evelyn J. Taylor ,  Mark A. Crawford

IPC分类号： A01N25/08 ,  A01N25/10 ,  A01N25/14 ,  A01N25/22 ,  A01N59/20 ,  A61K31/78

CPC分类号： A01N59/20

摘要： There is disclosed a granular copper hydroxide dry flowable bactericide/fungicide having improved biological activity and a method for making and using same. A bactericide/fungicide is made by forming a homogeneous aqueous slurry containing between approximately 5% and 20% by weight (based on the total weight of all dry ingredients) of a first dispersant selected from the group consisting of partially neutralized polyacrylic acid having a pH of between approximately 5 and 10 and an average molecular weight of between approximately 1,000 and 10,000 and lignin sulfonate, between approximately 0% and 5% by weight (based on the total weight of all dry ingredients) of a second dispersant for bentonite clay, between approximately 40% and 80% by weight (based on the total weight of all dry ingredients) phosphate stabilized cupric hydroxide and between approximately 6% and 30% by weight (based on the total weight of all dry ingredients) bentonite clay; and spray drying the slurry to thereby form a dry free flowing granular bactericide/fungicide product. The slurry can also include antifoam and wetting agents. Other partially neutralized polycarboxylic acid polymers useful as the first dispersant are also disclosed.

摘要翻译： 公开了具有改善的生物活性的颗粒状氢氧化铜干燥可流动杀菌剂/杀真菌剂及其制备和使用方法。 通过形成含有约5％至20％重量（基于所有干成分的总重量）的第一分散剂的均匀含水浆料制备杀菌剂/杀真菌剂，所述第一分散剂选自部分中和的具有pH的聚丙烯酸 在约5至10之间，平均分子量为约1,000至10,000和木质素磺酸盐，约0重量％至5重量％（基于所有干成分的总重量）的膨润土粘土的第二分散剂之间，介于 约40重量％和80重量％（基于所有干成分的总重量）磷酸盐稳定的氢氧化铜和约6重量％至30重量％（基于所有干成分的总重量）膨润土; 并喷雾干燥该浆料，从而形成干燥自由流动的颗粒状杀菌剂/杀真菌剂产品。 浆料还可以包括消泡剂和润湿剂。 还公开了可用作第一分散剂的其它部分中和的聚羧酸聚合物。

公开(公告)号：US5085645A

公开(公告)日：1992-02-04

申请号：US569797

申请日：1990-08-15

申请人： Edmund R. Purdy ,  Mark A. Crawford ,  Timothy J. Erskine ,  Gerald H. Peterson

发明人： Edmund R. Purdy ,  Mark A. Crawford ,  Timothy J. Erskine ,  Gerald H. Peterson

IPC分类号： A61M39/00 ,  A61M25/00 ,  A61M39/26

CPC分类号： A61M39/26

摘要： An over the needle catheter with adapter that has an integral valve in a passage. Distal and proximal parts form the adapter along an axis. The distal part communicates with a catheter. A hub conjugates with the proximal part and has a needle extending along the axis and through the passage when the hub is within the proximal part. A valve assembly has an elongate resilient member captured in the passage between the parts. A proximal portion of the valve assembly is engaged by a fitting to open the valve. A valve seat in the passage has a frusto-conical surface located coaxial about the axis and facing the distal part. The seat engages a chamfered surface on the elongate resilient member to seal and prevent flow and to allow flow when the seal is broken by axial compression of the elongate resilient member by the fitting. A septum like end across the elongate resilient member permits the needle to pass therethrough in a resealable fashion. The elongate resilient member has a diametrically reduced cylindrical body extending to the septum like end. The passage has an annular space about the reduced cylindrical body and terminates in a distal area. The distal area has flow channels which extend between the annular space and the distal part. A method has steps of locating the parts along an axis and capturing the elongate resilient member by engaging the axially aligned parts to force the elongate resilient member against a valve seat for sealing the passage and preventing flow. Placing a needle carried on a hub along the axis and through a septum like end of the elongate resilient member allows the needle to be withdrawn from the septum like end and to reseal the passage. Applying fastening means to secure the parts is a step.

公开(公告)号：US5044493A

公开(公告)日：1991-09-03

申请号：US249792

申请日：1988-09-27

申请人： Mark A. Crawford ,  T. Andrew Guhl ,  J. Robert Stanley

发明人： Mark A. Crawford ,  T. Andrew Guhl ,  J. Robert Stanley

IPC分类号： A61B19/02 ,  A61B19/04 ,  E06B9/44

CPC分类号： E06B9/44 ,  A61B42/40 ,  A61B50/30 ,  E06B2009/407 ,  E06B2009/445 ,  Y10S206/805

摘要： A kit comprises a tray with a well for a tourniquet, a dressing to use with a medical device inserted into a blood vessel. An antimicrobial treatment in the well disinfects an area of skin through which the medical device punctures the vessel. A pair of juxtaposed gloves with the finger ends, the hand parts and the cuff portions against one another are rolled up along their longitude from their fingers to their cuffs driving out air entrapped within the gloves. The process of rolling from the fingers to the cuffs leaves the cuffs of each glove at the periphery of the rolled generally cylindrical gloves for access to the inside of each when donning. A method for rolling gloves into a relatively cylindrical package, includes setting the gloves side by side with the finger ends, the hand parts, and the wrist or cuff portions juxtaposed. The finger portions are gathered into an axial bundle and rolled from the finger ends toward the palm or back hand parts driving out air within the gloves. Rolling along the elongate longitude of the gloves to the cuff or wrist portions, drives air from the cuffs and provides a cylindrical package. The method may include the added step of binding the rolled gloves with a band or tape. The compact package of gloves rolled up together along their longitude has binding about the middle to hold the rolled glove pair together so they are diametrically smaller than they are wide.

摘要翻译： 套件包括具有用于止血带的托盘的托盘，用于与插入血管的医疗装置一起使用的敷料。 井中的抗菌处理消毒了医疗器械穿过血管的皮肤区域。 手指末端的一对并置的手套，彼此相对的手部部分和袖口部分从他们的手指向他们的手指卷起到袖口上，从而驱赶夹在手套内的空气。 从手指滚动到袖口的过程在滚动的大致圆柱形手套的外围留下每个手套的袖口，以便在穿戴时进入每个手套的内部。 将手套滚动到相对圆筒形的包装中的方法包括将手指并排配置，手指部分和手腕或袖带部分并置。 手指部分聚集成轴向束并从手指端朝着手掌或后手部分滚动，从而驱除手套内的空气。 沿着手套的细长经度滚动到袖口或腕部，驱动袖带上的空气并提供圆柱形包装。 该方法可以包括用滚筒或胶带捆绑滚动的手套的附加步骤。 沿着经度一起卷起的手套的紧凑包装具有中间的约束力，将卷起的手套对保持在一起，因此它们比其宽度更小。