摘要:
It is an object of the present invention to provide a protein having a drug transport activity, a method for screening a compound that promotes or inhibits the activity of the drug transporter, a compound obtained by the method, an antibody against the drug transporter, a pharmaceutical composition comprising the same, or the like. The protein with a drug transport activity of the present invention has an amino acid sequence represented by SEQ ID NO: 1.
摘要翻译:本发明的目的是提供具有药物转运活性的蛋白质,用于筛选促进或抑制药物转运蛋白活性的化合物的方法,通过该方法获得的化合物,针对药物转运蛋白的抗体, 包含其的药物组合物等。 具有本发明的药物转运活性的蛋白质具有SEQ ID NO:1所示的氨基酸序列。
摘要:
An image forming apparatus includes an endless belt operating as an intermediate image transfer member. A plurality of process cartridges is juxtaposed along the endless belt. Each process cartridge includes a photosensitive drum confronting the endless belt and a developing agent carrying member disposed in confronting relation with the photosensitive drum for supplying toner to the photosensitive drum. A first conveying member is provided in each process cartridge. A second conveying member is provided in the housing, and the first conveying member conveys a recording sheet in cooperation with the second conveying member.
摘要:
A developing device includes: a casing; a developing roller rotatably supported to the casing; a resiliently deformable blade supported to the casing and extending in an axial direction of the developing roller; and a regulation portion. The developing roller is rotatable in a rotational direction and to carry a layer of developer thereon. The blade has a first surface facing the developing roller. The regulation portion is configured to be in contact with the developing roller to regulate a thickness of the layer of the developer. The blade is formed with a through-hole to allow a material of the regulation portion to pass therethrough to form the regulation portion, the through-hole being exclusively formed in a central area in the axial direction assuming that the blade were divided into three areas each having an identical length in the axial direction with each other.
摘要:
A gear device has an outer cylinder fixed to a first mating member and a crankshaft inside the outer cylinder. An external gear is mounted to an eccentric portion of the crankshaft and meshes with internal teeth of the outer cylinder. A carrier is fixed to a second mating member. Rocking rotation of the external gear rotates the carrier coaxially to the outer cylinder. A cylindrical body is inserted in an axial through-hole of the carrier. The carrier has a first portion on one end of the cylindrical body and a second portion on an axially intermediate portion of the cylindrical body. The other end of the cylindrical body extends toward a corresponding mating member while protruding axially beyond the second portion. An outer diameter of remaining portions of the cylindrical body do not exceed an outermost diameter of the portion on which the first and second portions are fit.
摘要:
A request change unit outputs a command as a request under control of a judgment control unit. A response condition determination unit determines a condition that is to be matched by a correct response which is to be returned from the other device-in-communication in reply to the command if the other device-in-communication operates in conformity with a protocol. A check unit checks a response received from the other device-in-communication in reply to the command, against the condition. If the received response does not match the condition but is correctable to match the condition as a result of the check, a response correction unit corrects the received response to match the condition under control of the judgment control unit.
摘要:
To provide a technology for improving the recording quality through edge correction of recording pulse in an optical disc apparatus. An optimum recording power of recording pulse is obtained through OPC processing according to a recording strategy with a first pulse timing; recording is performed by use of recording pulse with the optimum recording power; a first edge-shift amount of recording mark is measured from a reproduction signal to perform edge correction of recording pulse to form a second pulse timing of a recording strategy. Subsequently, recording is performed with pulse width variations of recording pulse to measure a second edge-shift amount of recording mark from a reproduction signal; and optimum edge positions of recording pulse are calculated based on the first edge-shift amount and the second edge-shift amount.
摘要:
In a display device used together with a playback apparatus such as an optical disk, a control is provided responding to a playback signal from an playback apparatus in order to prevent burn-out of CRT phosphor or deterioration of phosphor. A first controller controls the playback apparatus, and a second controller controls the display device, and those two controllers communicate with each other, thereby recognizing an operation status and a display status. Thus those two controllers control circuits and apparatus including a video control circuit which controls a contrast, whereby optimizing a display on a screen, and control status of an audio output, a power supply controller, and a playback apparatus controller.
摘要:
A digital convergence correction device converts correction data into serial data by using a parallel/serial converter, and further converts the serial data into an analog correction signal by using a serial input type digital/analog converter, and outputs the analog correction signal in order to correct misconvergence.