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公开(公告)号:US5225679A
公开(公告)日:1993-07-06
申请号:US825062
申请日:1992-01-24
申请人: Richard H. Clarke , Deming Tang
发明人: Richard H. Clarke , Deming Tang
CPC分类号: G01N33/2829 , G01N21/3577 , G01N2021/3177
摘要: Method and apparatus for monitoring hydrocarbon-based fuel properties by measuring the presence and amount of fuel component molecules in the fuel solution. Detection is made of absorption related to signature vibrational modes associated with the fuel component molecules when excited in the mid-IR. In one embodiment, a mid-IR light source illuminates the fuel in-situ and a narrow bandwidth detector associated with a vibrational mode signature detects absorbance as an indication of the presence and quantity of the fuel component in solution. From the determined fuel component quantity and known characteristics, the fuel solution properties are predicted. In one embodiment, octane rating and vapor pressure for a fuel solution is determined in-situ and in real time.
摘要翻译: 通过测量燃料溶液中燃料成分分子的存在和量来监测基于烃的燃料性质的方法和装置。 当在中红外激发时,检测与燃料成分分子相关的特征振动模式的吸收。 在一个实施例中,中红外光源原位照射燃料,并且与振动模式签名相关联的窄带宽检测器检测吸光度作为溶液中燃料成分的存在和数量的指示。 根据确定的燃料成分量和已知特性,预测燃料溶液性质。 在一个实施方案中,用于燃料溶液的辛烷值和蒸汽压力是在现场和实时地确定的。
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公开(公告)号:US5222496A
公开(公告)日:1993-06-29
申请号:US930141
申请日:1992-08-14
申请人: Richard H. Clarke , Qian Wang
发明人: Richard H. Clarke , Qian Wang
IPC分类号: A61B5/00
CPC分类号: A61B5/1455 , A61B5/14532 , A61B5/1459 , A61B2562/0233 , A61B2562/043
摘要: Systems and methods for non-invasive blood analysis for the presence of glucose are disclosed in which blood is illuminated at a plurality of discrete wavelengths selected from the near infrared spectrum. Measurements of the intensity of transmitted or reflected light at such wavelengths are taken, and an analysis of transmittance or reflectance ratios for various wavelengths is performed. Changes in the ratios can be correlated with specific near infrared (IR) absorption peak for glucose at about 1600 nm +/-15 nm which varies with concentration of the analyte (the data wavelength) and the a second (reference) wavelength being sufficiently removed from the first so that measurements of light absorption at this second wavelength are relatively insensitive to the concentration of the analyte and yet the second wavelength is sufficiently close to the first wavelength to minimize interference from scattering effects and the like. Typically, the window bracketing these closely spaced wavelengths will be less than about 300 nm and preferably less than about 60 nm wide and, in some instances, more preferably less than about 30 nm wide.
摘要翻译: 公开了用于葡萄糖存在的非侵入性血液分析的系统和方法,其中以从近红外光谱中选择的多个离散波长照射血液。 测量这些波长的透射光或反射光的强度,并对各种波长的透射率或反射率进行分析。 比率的变化可以与大约1600nm±15nm的葡萄糖的特定近红外(IR)吸收峰相关,其随着分析物的浓度(数据波长)和第二(参考)波长被充分去除而变化 从而使得在该第二波长处的光吸收的测量对分析物的浓度相对不敏感,而第二波长足够接近于第一波长,以最小化来自散射效应等的干扰。 通常,包围这些紧密间隔的波长的窗口将小于约300nm,优选小于约60nm宽,并且在一些情况下更优选小于约30nm宽。
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23.
公开(公告)号:US5139334A
公开(公告)日:1992-08-18
申请号:US583808
申请日:1990-09-17
申请人: Richard H. Clarke
发明人: Richard H. Clarke
IPC分类号: G01N21/65
CPC分类号: G01N21/65
摘要: A system is disclosed for measuring properties of samples associated with the distribution of hydrocarbons in the sample. The system includes a low resolution laser Raman spectrometer coupled to photodetectors that integrate the intensity of the scattered Raman radiation. The system further includes microprocessor means that separate the Raman spectrum into two spectral ranges, calculates a ratio of the integrated intensities corresponding to these ranges and interpolates that ratio with a correlating function to obtain the measurement of the property of interest.
摘要翻译: 公开了一种用于测量与样品中碳氢化合物分布相关的样品的性质的系统。 该系统包括耦合到光电检测器的低分辨率激光拉曼光谱仪,其结合散射拉曼辐射的强度。 该系统还包括将拉曼光谱分离成两个光谱范围的微处理器装置,计算与这些范围相对应的积分强度的比率,并用相关函数内插该比率以获得感兴趣的属性的测量。
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公开(公告)号:US5053033A
公开(公告)日:1991-10-01
申请号:US595033
申请日:1990-10-10
申请人: Richard H. Clarke
发明人: Richard H. Clarke
CPC分类号: A61N5/0601 , A61B2017/22002 , A61M25/104 , A61N2005/0661
摘要: Restenosis following angioplasty can be inhibited by reducing the proliferation of smooth muscle cells in the blood vessel walls at an angioplasty site, and such reduction in cell proliferation can be accomplished by irradiating the angioplasty site with radiation in the ultraviolet (UV) wavelength range. The ultraviolet radiation is preferably delivered via an optical fiber or other waveguide incorporated, for example, into a percutaneous catheter. In operation, the ultraviolet radiation kills smooth muscle cells at the site, thereby reducing the risk of restenosis, while minimizing damage to surrounding tissue.
摘要翻译: 通过减少血管成形术部位的血管壁中的平滑肌细胞的增殖可以抑制血管成形术后的再狭窄,并且可以通过用紫外(UV)波长范围的辐射照射血管成形术部位来实现细胞增殖的减少。 紫外线辐射优选经由例如并入到经皮导管中的光纤或其它波导输送。 在操作中,紫外线辐射杀死现场的平滑肌细胞,从而减少再狭窄的风险,同时最大限度地减少对周围组织的损伤。
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公开(公告)号:US4862886A
公开(公告)日:1989-09-05
申请号:US731961
申请日:1985-05-08
CPC分类号: G02B6/4296 , A61B18/245 , A61B2017/00154 , A61B2017/00194 , A61B2017/22051 , A61B90/39 , G02B2006/4297
摘要: A laser therapy system having improved effectiveness in surgical use, particularly in laser angioplasty, can be formed by employing a pulsed source of radiation. The pulsed energy source is preferably an excimer laser having a coherent beam of ultraviolet radiation and preferably is employed in conjunction with a dye laser to produce an output beam which is tunable over a wide portion of the ultraviolet and visible spectrum. The output beam is coupled via a novel coupling device to an optical fiber disposed within a surgical instrument, for example, a percutaneous catheter. The operative components are sealed in a gas-tight, liquid-tight housing. An electronic controller monitors and adjusts the output energy density, duration, and pulse repetition rate. In operation, a pulsed, high energy beam of extremely short duration is available to remove atherosclerotic plague with less damage to the underlying tissue and less chance of perforating the blood vessel wall.
摘要翻译: 可以通过采用脉冲辐射源形成具有改善的外科用途有效性的激光治疗系统,特别是在激光血管成形术中。 脉冲能量源优选是具有相干紫外线辐射束的准分子激光器,并且优选与染料激光器结合使用以产生可在紫外线和可见光谱的宽部分上调节的输出光束。 输出光束通过新颖的耦合装置耦合到设置在外科器械例如经皮导管内的光纤。 操作部件密封在气密,液密的外壳中。 电子控制器监视和调整输出能量密度,持续时间和脉冲重复率。 在操作中,具有极短持续时间的脉冲的高能量束可用于以较少的对下面的组织的损伤去除动脉粥样硬化性瘟疫并且具有较小的穿孔血管壁的机会。
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