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公开(公告)号：US6017328A
公开(公告)日：2000-01-25
申请号：US695596
申请日：1996-08-12
CPC分类号： A61M5/3202 , A61M25/0606 , A61M5/158 , A61M2005/1581 , A61M2005/1585 , A61M2005/1587 , A61M5/001
摘要： The present invention is an injection port assembly for subcutaneous delivery of medication. A single molded body has a soft cannula extending downward from a generally flat bottom surface and a self-sealing septum mounted at the center of a top surface which is generally of a concave shape sloping downward towards its outer perimeter at which point the single body is very thin. The single body also has a tubular extension which is directed outward parallel to the skin's surface. A metal needle which penetrates through the septum and through the lumen of the soft cannula is used for inserting the cannula through the skin. Once the soft cannula is placed subcutaneously, the needle is removed and an adhesive tape is placed over the single body and onto the skin beyond the body's outer perimeter. By having a distal section of the needle which is smaller in diameter as compared to most of the needle's length, and by having the soft cannula fit tightly onto the needle, most of the cannula's length will be in tension during insertion thereby preventing an accordion-like compressional failure of the cannula. A quick-release connector on the proximal end of the tubular extension or mounted directly on the injection port assembly allows the tubing connecting the injection port assembly to a portable medication pump to be disconnected when the patient showers or performs some similar activity.
摘要翻译： 本发明是用于皮下递送药物的注射口组件。 单个成型体具有从大致平坦的底部表面向下延伸的软套管和安装在顶表面的中心处的自密封隔膜，该顶部表面通常具有朝向其外周向下倾斜的凹形，在该点处，单体为 很瘦。 单体还具有向外平行于皮肤表面指向的管状延伸部。 穿过隔膜并通过软套管的内腔的金属针用于插入套管穿过皮肤。 一旦软套管皮下放置，取下针头，并将胶带放置在单个身体上方并超过身体外周的皮肤上。 通过使针的远端部分与针的大部分长度相比直径较小，并且通过使软管紧紧地配合到针上，插管的大部分长度将在插入期间处于张力状态，从而防止手风琴 - 像套管的压缩失败。 管状延伸部的近端上的快速释放连接器或直接安装在注射口组件上的快速连接器允许当患者淋浴或执行某些类似的活动时将连接注射口组件的便携式药物泵断开连接。
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公开(公告)号：US09254211B2
公开(公告)日：2016-02-09
申请号：US11244777
申请日：2005-10-06
CPC分类号： A61F2/958 , A61F2/95 , A61M25/104 , A61M2025/1056 , A61M2025/1063
摘要： A thin-walled guide wire tube is fixedly and sealably attached to both a proximal section and a distal section of a balloon angioplasty catheter. A stent is co-axially mounted onto the inflatable balloon of the balloon angioplasty catheter. Because the guide wire tube forms an inner liner for the balloon angioplasty catheter, the fluid inflation lumen of the catheter is sealed so the inflation liquid that pressurizes the balloon will not leak as it would be if there were no “inner liner” and the balloon angioplasty catheter were attached to the guide wire itself. By not having a traditional inner shaft through which a conventional guide wire slides, the deflated balloon on which the stent is mounted can have a reduced diameter.
摘要翻译： 薄壁导丝管固定并密封地附接到球囊血管成形术导管的近端部分和远端部分。 支架同轴地安装在球囊血管成形术导管的可充气球囊上。 由于导丝管形成球囊血管成形术导管的内衬，导管的流体膨胀腔被密封，使得气囊加压的充气液体将不会像没有“内衬”和气囊 血管成形术导管附着于导丝本身。 通过不具有传统导丝通过其传播的传统内轴，其上安装有支架的放气气球可以具有减小的直径。
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23.发明授权Introducer sheath with thin-walled shaft and improved means for attachment to the skin 有权引导器鞘与薄壁轴和改进的附着到皮肤的手段公开(公告)号：US08348925B2
公开(公告)日：2013-01-08
申请号：US13032876
申请日：2011-02-23
IPC分类号： A61M25/00
CPC分类号： A61M25/0662 , A61M5/1418 , A61M25/005 , A61M25/0108 , A61M25/02 , A61M2025/0266 , A61M2025/028 , A61M2025/0286 , A61M2209/088
摘要： An introducer sheath for placement into the vascular system of a human subject. The introducer sheath has a tubular shaft, a side arm, and a hemostasis valve with an integrated attachment mechanism for attaching and detaching a proximal end of the introducer sheath to and from the skin of the human subject.
摘要翻译： 用于放置在人类受试者的血管系统中的导引鞘。 引导器护套具有管状轴，侧臂和具有集成附接机构的止血阀，用于将引导器护套的近端附接到人类受试者的皮肤和从皮肤脱离皮肤。
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公开(公告)号：US08038624B2
公开(公告)日：2011-10-18
申请号：US10642245
申请日：2003-08-18
申请人： David R. Fischell , Tim A. Fischell , Jonathan Harwood , Robert E. Fischell , Steven R. Johnson
发明人： David R. Fischell , Tim A. Fischell , Jonathan Harwood , Robert E. Fischell , Steven R. Johnson
IPC分类号： A61B5/0452
CPC分类号： A61B5/02455 , A61B5/0031 , A61B5/04012 , A61B5/0422 , A61B5/0452 , A61B5/0456 , A61B5/0468 , A61B5/0472 , A61B5/746 , A61B5/7465 , A61B2560/0209
摘要： Disclosed is a system for the detection of cardiac events (a guardian system) that includes an implanted device called a cardiosaver, a physician's programmer and an external alarm system. The system is designed to provide early detection of cardiac events such as acute myocardial infarction or exercise induced myocardial ischemia caused by an increased heart rate or exertion. The system can also alert the patient with a less urgent alarm if a heart arrhythmia is detected. Using one or more detection algorithms, the cardiosaver can detect a change in the patient's electrogram that is indicative of a cardiac event within five minutes after it occurs and then automatically warn the patient that the event is occurring. To provide this warning, the guardian system includes an internal alarm sub-system (internal alarm means) within the cardiosaver and/or an external alarm system (external alarm means). If the guardian system is put into a pacemaker, the algorithm can utilize a different analysis of the electrogram depending on whether or not the pacemaker is actually pacing the heart.
摘要翻译： 公开了一种用于检测心脏事件（监护系统）的系统，其包括称为心脏切除器的植入装置，医师编程器和外部警报系统。 该系统旨在提供心脏事件的早期检测，例如由心率增加或运动引起的急性心肌梗死或运动诱发的心肌缺血。 如果检测到心律失常，该系统还可以警告患者不太紧急的警报。 使用一个或多个检测算法，心脏扫描器可以检测患者的电描记图中的变化，其指示在发生后五分钟内的心脏事件，然后自动向患者发出事件发生。 为了提供此警告，监护系统包括在心脏保护器内和/或外部报警系统（外部报警装置）内的内部报警子系统（内部报警装置）。 如果将监护人系统放入心脏起搏器，该算法可以根据起搏器是否实际起搏心脏，对电图进行不同的分析。
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公开(公告)号：US20110137194A1
公开(公告)日：2011-06-09
申请号：US13025476
申请日：2011-02-11
IPC分类号： A61B5/0456
CPC分类号： A61B5/02455 , A61B5/0031 , A61B5/04012 , A61B5/0422 , A61B5/0452 , A61B5/0456 , A61B5/0468 , A61B5/0472 , A61B5/746 , A61B5/7465 , A61B2560/0209
摘要： Disclosed is a system for the detection of cardiac events (a guardian system) that includes an implanted device called a cardiosaver, a physician's programmer and an external alarm system. The system is designed to provide early detection of cardiac events such as acute myocardial infarction or exercise induced myocardial ischemia caused by an increased heart rate or exertion. The system can also alert the patient with a less urgent alarm if a heart arrhythmia is detected. Using one or more detection algorithms, the cardiosaver can detect a change in the patient's electrogram that is indicative of a cardiac event within five minutes after it occurs and then automatically warn the patient that the event is occurring. To provide this warning, the guardian system includes an internal alarm sub-system (internal alarm means) within the cardiosaver and/or an external alarm system (external alarm means). If the guardian system is put into a pacemaker, the algorithm can utilize a different analysis of the electrogram depending on whether or not the pacemaker is actually pacing the heart.
摘要翻译： 公开了一种用于检测心脏事件（监护系统）的系统，其包括称为心脏切除器的植入装置，医师编程器和外部警报系统。 该系统旨在提供心脏事件的早期检测，例如由心率增加或运动引起的急性心肌梗死或运动诱发的心肌缺血。 如果检测到心律失常，该系统还可以警告患者不太紧急的警报。 使用一个或多个检测算法，心脏扫描器可以检测患者的电描记图中的变化，其指示在发生后五分钟内的心脏事件，然后自动向患者发出事件发生。 为了提供此警告，监护系统包括在心脏保护器内和/或外部报警系统（外部报警装置）内的内部报警子系统（内部报警装置）。 如果将监护人系统放入心脏起搏器，该算法可以根据起搏器是否实际起搏心脏，对电图进行不同的分析。
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公开(公告)号：US07037327B2
公开(公告)日：2006-05-02
申请号：US09961927
申请日：2001-09-24
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61F2/90 , A61F2002/9583 , A61F2250/0018 , A61F2250/0042 , A61F2250/0048
摘要： A hybrid stent that is defined as having a central section that is balloon expandable and end sections that are self-expanding. The entire stent is mounted on a balloon of a balloon angioplasty catheter. One way to retain the self-expanding portion of the stent onto a balloon onto which it has been nested is to place a cylindrical elastomer tube around each of the self-expanding end sections of the stent. Another way to retain the hybrid stent onto a stent delivery system is to use a conventional sheath that is pulled back to initiate stent deployment
摘要翻译： 被定义为具有球囊可膨胀的中心部分和自膨胀的末端部分的混合支架。 整个支架安装在球囊血管成形术导管的球囊上。 将支架的自膨胀部分保持在其已经嵌套在其上的气球上的一种方法是将圆柱形弹性体管围绕在支架的每个自扩张端部分上。 将混合支架保持在支架输送系统上的另一种方法是使用被拉回以启动支架部署的常规护套
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公开(公告)号：US07011673B2
公开(公告)日：2006-03-14
申请号：US10107221
申请日：2002-03-26
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2/958 , A61M2025/0186 , A61M2025/1004
摘要： The present invention is a stent delivery system that uses a short section of a guide wire that is fixedly attached to a distal section of a balloon angioplasty catheter. By not having a guide wire that slides through the balloon of the balloon angioplasty catheter, the balloon on which the stent is mounted can have a reduced diameter. Therefore, the outside diameter of the undeployed stent mounted onto that balloon is also minimized. This provides a minimum profile, i.e., a minimum outside diameter, for the stent. A minimum profile at the distal section of the stent delivery system is highly advantageous for improving the percentage of cases that can be treated by means of direct stenting; i.e., without requiring pre-dilation of a stenosis.
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公开(公告)号：US06547817B1
公开(公告)日：2003-04-15
申请号：US09596074
申请日：2000-06-16
IPC分类号： A61M2900
CPC分类号： A61F2/844 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2002/825 , A61F2002/91533 , A61F2002/9155 , A61F2210/0019
摘要： An expandable stent for delivery to a coronary artery. The stent has at least two longitudinally spaced apart circumferential rings having closed ends. Each of the circumferential rings has at least two peak segments and at least two valley segments. At least one longitudinally extending connector extends between adjacent circumferential rings. The connector has a first end portion fixedly connected to a first circumferential ring and a second end portion fixedly connected to an adjacent circumferential ring. The connector has at least one circumferentially extending turn back portion between its first and second end portions that can expand or contract in length while being passed through a curved coronary artery.
摘要翻译： 用于输送到冠状动脉的可扩张支架。 支架具有至少两个具有闭合端的纵向间隔开的周向环。 每个周向环具有至少两个峰段和至少两个谷段。 至少一个纵向延伸的连接件在相邻周向环之间延伸。 连接器具有固定地连接到第一周向环的第一端部和固定地连接到相邻周向环的第二端部。 连接器在其第一和第二端部之间具有至少一个沿圆周方向延伸的折回部分，其能够在穿过弯曲的冠状动脉的同时膨胀或收缩。
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公开(公告)号：US06315708B1
公开(公告)日：2001-11-13
申请号：US09540629
申请日：2000-03-31
IPC分类号： A61N500
CPC分类号： A61F2/958 , A61F2/90 , A61F2002/9583 , A61F2250/0018 , A61F2250/0042 , A61F2250/0048
摘要： The present invention is a hybrid stent that is defined as having a central section that is balloon expandable and end sections that are self-expanding. The entire stent is mounted on a balloon of a balloon angioplasty catheter. One way to retain the self-expanding portion of the stent onto a balloon onto which it has been nested is to place a cylindrical elastomer tube around each of the self-expanding end sections of the stent. Another way to retain the hybrid stent onto a stent delivery system is to use a conventional sheath that is pulled back to initiate stent deployment
摘要翻译： 本发明是一种混合型支架，其被定义为具有球囊可膨胀的中心部分和自膨胀的端部。 整个支架安装在球囊血管成形术导管的球囊上。 将支架的自膨胀部分保持在其已经嵌套在其上的气球上的一种方法是将圆柱形弹性体管围绕在支架的每个自扩张端部分上。 将混合支架保持在支架输送系统上的另一种方法是使用被拉回以启动支架部署的常规护套
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公开(公告)号：US6086604A
公开(公告)日：2000-07-11
申请号：US263518
申请日：1999-03-05
CPC分类号： A61F2/844 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2002/825 , A61F2002/91533 , A61F2002/9155 , A61F2210/0019
摘要： The present invention provides for an expandable stent (10 or 20) for use in an artery or other vessel of a human body. The stent structure (10 or 20) maintains the patency of the vessel within which the stent (10 or 20) is expanded radially outward. One embodiment of the present invention is a stent (10) having a multiplicity of frames (12) joined together by at least two undulating longitudinal structures (14L and 14R) which can readily change their length in the longitudinal direction so as to provide increased longitudinal flexibility for the stent (10) for easy passage through and placement within a curved vessel such as a coronary artery. The stent (20) is an embodiment of the present invention having frames (22) joined with longitudinal structures (24B, 24T and 24R) and formed from a single, thin-walled piece of metal by laser cutting or chemical etching. Because the stent (20) is fabricated from a single piece of metal, it provides a multiplicity of closed perimeter cells that are formed as a continuous metal structure.
摘要翻译： 本发明提供一种用于人体动脉或其他血管的可扩张支架（10或20）。 支架结构（10或20）保持支架（10或20）径向向外扩张的容器的通畅性。 本发明的一个实施例是具有通过至少两个起伏的纵向结构（14L和14R）连接在一起的多个框架（12）的支架（10），其可以容易地改变其在纵向上的长度，从而提供增加的纵向 支架（10）的灵活性容易通过并放置在诸如冠状动脉的弯曲容器内。 支架（20）是本发明的实施例，其具有通过激光切割或化学蚀刻由单个薄壁金属片形成的具有纵向结构（24B，24T和24R）的框架（22）。 因为支架（20）由单块金属制成，所以它提供了多个形成为连续金属结构的封闭周边细胞。
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