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21.发明授权公开(公告)号：US07713232B2
公开(公告)日：2010-05-11
申请号：US11460635
申请日：2006-07-28
IPC分类号： G01N35/10
CPC分类号： A61J1/1443 , A61J1/1456 , A61J1/1475 , A61M5/142 , A61M5/1723 , A61M5/3145 , A61M31/005 , B01L3/502 , B01L2300/044 , B01L2300/0681 , G06F19/3468
摘要： A system for injecting an injectate into patient includes a first pressurizable container for holding the injectate; a patient interface in fluid connection with the first pressurizable container, the patient interface being adapted to pass the injectate into tissue of the patient; a powered injector in operative connection with the first pressurizable container to pressurize the injectate; a controller system in operative connection with powered injector; and a stereotactic localization frame adapted to be placed in operative connection with the patient interface to assist in controlling localization of the patient interface. A system for processing cells (and/or other injectate components) includes a container and a plunger adapted to be slidably positioned within the container. The system includes at least one inlet port through which a fluid can enter the system and at least one effluent port through which an effluent can exit the system. The plunger section forms a sealing engagement with the inner wall of the container such that rearward motion of the plunger is adapted to draw fluid into the system via the inlet and forward motion of the plunger is adapted to force effluent out of the system via the effluent port.
摘要翻译： 用于将注射器注射到患者体内的系统包括用于保持注射器的第一可加压容器; 与所述第一可加压容器流体连接的患者接口，所述患者接口适于将所述注射器通入患者的组织; 动力注射器，其与所述第一可加压容器可操作地连接以对所述注射器加压; 与动力注射器操作连接的控制器系统; 以及适于与病人界面操作连接的立体定向定位框架，以协助控制患者界面的定位。 用于处理细胞（和/或其它注射组分）的系统包括适于可滑动地定位在容器内的容器和柱塞。 该系统包括至少一个入口，流体可以通过该入口进入系统和至少一个流出物端口，流出物可通过该至少一个出口端口离开系统。 柱塞部分形成与容器的内壁的密封接合，使得柱塞的向后运动适于经由入口将流体引入系统，并且柱塞的向前运动适于通过流出物强制流出系统的流出物 港口。
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公开(公告)号：US06440107B1
公开(公告)日：2002-08-27
申请号：US09507274
申请日：2000-02-18
IPC分类号： A61M500
CPC分类号： A61M39/14 , A61M2039/1033 , A61M2039/1072 , Y10S604/905
摘要： An aseptic connector comprises a first member and a second member. The first member preferably includes a resilient septum, and the second member preferably includes a penetrating member. Preferably, the septum is formed from an elastomeric material such as a silicone elastomer. The penetrating member preferably includes an extending penetrating element to penetrate the resilient septum. The aseptic connector further comprises a resilient sealing element that contacts the penetrating member and one of an inner wall of the first member and an inner wall of the second member to create a seal between the penetrating member and one of the inner wall of the first member and the inner wall of the second member. The seal created is suitable to withstand relatively high pressures (for example, those experienced during the injection of contrast media in CT procedures). A fluid delivery system comprising at least a first aseptic connector as described above is also provided.
摘要翻译： 无菌连接器包括第一构件和第二构件。 第一构件优选地包括弹性隔膜，并且第二构件优选地包括穿透构件。 优选地，隔膜由诸如硅氧烷弹性体的弹性体材料形成。 穿透构件优选地包括穿透弹性隔膜的延伸穿透元件。 所述无菌连接器还包括弹性密封元件，所述弹性密封元件接触所述穿透构件并且所述第一构件的内壁和所述第二构件的内壁中的一个在所述穿透构件与所述第一构件的内壁中的一个之间形成密封 和第二构件的内壁。 产生的密封件适合于承受相对高的压力（例如，在CT程序中注射造影剂期间经历的那些）。 还提供了至少包括如上所述的第一无菌连接器的流体递送系统。
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23.发明授权Aseptic connector and fluid delivery system using such an aseptic connector 失效无菌连接器和流体输送系统使用这种无菌连接器
公开(公告)号：US6096011A
公开(公告)日：2000-08-01
申请号：US15175
申请日：1998-01-29
CPC分类号： A61M39/14 , A61M2039/1033 , A61M2039/1072 , Y10S604/905
摘要： An aseptic connector comprises a first member and a second member. The first member preferably includes a resilient septum, and the second member preferably includes a penetrating member. Preferably, the septum is formed from an elastomeric material such as a silicone elastomer. The penetrating member preferably includes an extending penetrating element to penetrate the resilient septum. The aseptic connector further comprises a resilient sealing element that contacts the penetrating member and one of an inner wall of the first member and an inner wall of the second member to create a seal between the penetrating member and one of the inner wall of the first member and the inner wall of the second member. The seal created is suitable to withstand relatively high pressures (for example, those experienced during the injection of contrast media in CT procedures). A fluid delivery system comprising at least a first aseptic connector as described above is also provided.
摘要翻译： 无菌连接器包括第一构件和第二构件。 第一构件优选地包括弹性隔膜，并且第二构件优选地包括穿透构件。 优选地，隔膜由诸如硅氧烷弹性体的弹性体材料形成。 穿透构件优选地包括穿透弹性隔膜的延伸穿透元件。 所述无菌连接器还包括弹性密封元件，所述弹性密封元件接触所述穿透构件并且所述第一构件的内壁和所述第二构件的内壁中的一个在所述穿透构件与所述第一构件的内壁中的一个之间形成密封 和第二构件的内壁。 产生的密封件适合于承受相对高的压力（例如，在CT程序中注射造影剂期间经历的那些）。 还提供了至少包括如上所述的第一无菌连接器的流体递送系统。
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公开(公告)号：US20110049866A1
公开(公告)日：2011-03-03
申请号：US12550786
申请日：2009-08-31
CPC分类号： A61M5/162 , A61J1/1406 , A61M5/007 , A61M39/24 , A61M2005/1623 , B33Y70/00 , B33Y80/00 , Y10T137/3115 , Y10T137/7856 , Y10T137/8122 , Y10T137/86348
摘要： A fluid connector includes an extending section including a spiked end to pierce the container port. The extending section includes at least one air conduit and at least one fluid conduit therethrough. The extending section further includes a first abutment member and second abutment member. The first abutment member is adapted to abut a first or air side of the container port upon piercing of the container port. The second abutment member is spaced from the first abutment member and is adapted to abut a second or fluid sided of the container port. The fluid connector can further include grasping members extending from the extending section to facilitate rotation of the extending section relative to the container port during piercing thereof. The fluid connector can also include a check valve in fluid connection with the air line. In several embodiments, the check valve is positioned within the extending section.
摘要翻译： 流体连接器包括延伸部分，其包括尖端以刺穿容器端口。 延伸部分包括至少一个空气管道和至少一个通过其中的流体管道。 延伸部分还包括第一邻接构件和第二邻接构件。 第一抵接构件适于在穿过容器端口时抵靠容器口的第一或空气侧。 第二邻接构件与第一邻接构件间隔开并且适于邻接容器口的第二或流体侧。 流体连接器还可以包括从延伸部分延伸的抓握构件，以便于在穿孔期间使延伸部分相对于容器端口旋转。 流体连接器还可以包括与空气管线流体连接的止回阀。 在几个实施例中，止回阀定位在延伸部分内。
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公开(公告)号：US06733477B2
公开(公告)日：2004-05-11
申请号：US09731108
申请日：2000-12-06
IPC分类号： A61M500
CPC分类号： A61M5/14546 , A61M5/385 , A61M2005/1403
摘要： A syringe includes a body and a plunger disposed therein. The body includes a nozzle formed therein and at least one hub member connected thereto or integrally formed thereon for holding an end of a connector tube. The connector tube includes two ends, each end preferably being connected to a respective hub member to retain the connector tube in contact with the syringe. Preferably, the syringe and the connector tube are packaged in a pre-connected condition for ease of use by the customer. Furthermore, flexible inlet tubing for connection to a syringe for filling the syringe with contrast media, for example, is described. The inlet tubing permits filling of the syringe from either a bag or a bottle and may remain attached to the syringe so that it forms at least a part of the connection to the patient. In addition, an apparatus for facilitating the purge of air from a connector tube that will ultimately be connected between a syringe and a patient is described. The apparatus includes a purging tube connected to the distal end of the connector tubing from the syringe. The purging tube includes a venting cap at its distal end. A flow inhibitor is positioned under the venting cap to cooperate with the venting cap by discouraging the discharge of fluid from the distal end of the purging tube while permitting the discharge of air therefrom.
摘要翻译： 注射器包括主体和设置在其中的柱塞。 主体包括形成在其中的喷嘴和与其连接或一体地形成在其上的至少一个毂构件，用于保持连接器管的端部。 连接器管包括两个端部，每个端部优选地连接到相应的毂部件，以将连接器管保持与注射器接触。 优选地，注射器和连接管被包装在预连接状态中，以便客户易于使用。 此外，描述了用于连接到注射器的柔性入口管，用于例如用造影剂填充注射器。 入口管允许从袋或瓶中填充注射器，并且可以保持附接到注射器，使得其形成与患者的连接的至少一部分。 此外，描述了一种便于从最终连接在注射器和患者之间的连接管吹扫空气的装置。 该装置包括从注射器连接到连接管的远端的清洗管。 吹扫管在其远端包括通气盖。 流动抑制剂位于排气盖下面，以与通气帽配合，通过阻止从清洗管的远端排出流体，同时允许排出空气。
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26.发明授权Devices, systems and methods for delivery of a fluid into a patient during a magnetic resonance procedure 有权用于在磁共振程序期间将流体输送到患者体内的装置，系统和方法公开(公告)号：US07632245B1
公开(公告)日：2009-12-15
申请号：US10921083
申请日：2004-08-18
申请人： Kevin P. Cowan , Frederick W. Trombley, III , David M. Reilly , David M. Griffiths , George J. Misic , Keith Callan
发明人： Kevin P. Cowan , Frederick W. Trombley, III , David M. Reilly , David M. Griffiths , George J. Misic , Keith Callan
IPC分类号： A61M5/19
CPC分类号： A61M5/14526 , A61M5/007 , A61M2039/0009 , A61M2205/3362
摘要： A device for injection of a fluid into a patient includes a container adapted to hold the fluid and defining an outlet through which the fluid can exit the container. A pressurizing mechanism is in connection with the container for pressurizing the fluid, and an actuator is in fluid connection with the outlet. The actuator has a first state in which fluid is prevented from flowing through the outlet and a second state in which fluid can flow through the outlet. The injection device further includes a flow regulator to control the flow rate of fluid in fluid connection with the outlet. The container, the pressurizing mechanism, the actuator and the flow regulator can be MR compatible, thereby making the device suitable for use in or near the bore of an MR scanner.
摘要翻译： 用于向患者注射流体的装置包括适于保持流体并限定出口的容器，流体可通过该出口离开容器。 加压机构与用于对流体加压的容器连接，并且致动器与出口流体连接。 致动器具有防止流体流过出口的第一状态和流体可以流过出口的第二状态。 注射装置还包括流量调节器以控制与出口流体连接的流体的流速。 容器，加压机构，致动器和流量调节器可以是MR兼容的，从而使得该装置适合于在MR扫描器的孔中或附近使用。
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公开(公告)号：US07025757B2
公开(公告)日：2006-04-11
申请号：US10067003
申请日：2002-02-04
CPC分类号： A61M5/31581 , A61M5/007 , A61M5/14546 , A61M5/14566 , A61M5/31593 , A61M5/31595
摘要： A syringe loading/filling device (or “syringe loader”) includes a syringe mounting mechanism adapted to cooperate with an attachment mechanism of a syringe to attach the syringe to the syringe loader and a drive member adapted to impart motion to the syringe plunger. The syringes for use with the syringe loader include a syringe plunger slidably disposed therein and an attachment mechanism for attachment of the syringe to an injector. Such injectors include a mounting mechanism adapted to cooperate with the attachment mechanism on the syringe to mount the syringe on the injector.
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公开(公告)号：US08281807B2
公开(公告)日：2012-10-09
申请号：US12550786
申请日：2009-08-31
CPC分类号： A61M5/162 , A61J1/1406 , A61M5/007 , A61M39/24 , A61M2005/1623 , B33Y70/00 , B33Y80/00 , Y10T137/3115 , Y10T137/7856 , Y10T137/8122 , Y10T137/86348
摘要： A fluid connector system features a stopper and an extending section. Installable within an outlet of a fluid container, the stopper defines a passage therethrough. Defining air and fluid conduits, the extending section has a first abutment member threadably connectible thereto and a second abutment member affixed thereto. The extending section is adapted to be extended through the passage of the stopper when assembled thereto. When the first abutment member is tightened about the extending section, the first and second abutment members abut against the exterior and interior sides, respectively, of the stopper. With the stopper installed within the outlet and the extending section and the abutment members therewith assembled to the stopper thereby sealing the passage therein, fluid within the container may be extracted via the fluid conduit as air exterior to the container flows therein via the air conduct to displace the fluid being extracted from the container.
摘要翻译： 流体连接器系统具有止动器和延伸部分。 可安装在流体容器的出口内，止动器限定穿过其中的通道。 定义空气和流体管道，延伸部分具有可螺纹连接到其上的第一邻接构件和固定到其上的第二抵接构件。 延伸部分适于在组装时延伸通过止动件的通道。 当第一抵接构件围绕延伸部分紧固时，第一和第二抵接构件分别抵靠止动件的外侧和内侧。 当止动件安装在出口内时，延伸部分和抵靠部件组装到止动器上，从而密封其中的通道，容器内的流体可以经由流体导管抽出，因为容器外部的空气经由空气导管流入其中， 使从容器中提取的流体移位。
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29.发明授权Medical container loading system and method for use with fluid containers, syringes and medical injectors 有权用于流体容器，注射器和医疗注射器的医疗容器装载系统和方法公开(公告)号：US07240882B2
公开(公告)日：2007-07-10
申请号：US10718260
申请日：2003-11-20
申请人： Drew Degentesh , Matthew Beale , John Crowley , Matthew Goodworth , David M. Reilly , Frederick W. Trombley, III , Mark Trocki
发明人： Drew Degentesh , Matthew Beale , John Crowley , Matthew Goodworth , David M. Reilly , Frederick W. Trombley, III , Mark Trocki
IPC分类号： A47F5/08
CPC分类号： A61M5/14546 , A61M5/14566
摘要： A medical container loading system includes a medical container loading device and a fill station. The fill station is located proximate to the medical container loading device and includes a mounting plate and a holding assembly. The holding assembly is connected to the mounting plate for supporting a medical fluid container adapted for fluid communication with a medical container, such as a syringe, used in the medical container loading device. The holding assembly may include a fixed support and a movable support, which maintain the medical fluid container in the holding assembly. The fixed support may be funnel-shaped with a smooth or stepped inner wall. The fixed support may also be rectangular shaped and have an inclined inner wall or support for supporting the body of the medical fluid container. The movable support may be a resiliently biased support arm or an adjustable strap.
摘要翻译： 医疗容器装载系统包括医疗容器装载装置和填充站。 填充站位于医疗容器装载装置附近，并且包括安装板和保持组件。 保持组件连接到安装板，用于支撑适于与用于医疗容器装载装置的医疗容器（例如注射器）流体连通的医用流体容器。 保持组件可以包括固定支撑件和将医疗流体容器保持在保持组件中的可移动支撑件。 固定支撑件可以是具有平滑或阶梯式内壁的漏斗形。 固定支撑件也可以是矩形的并且具有用于支撑医用流体容器的主体的倾斜内壁或支撑件。 可移动支撑件可以是弹性偏置的支撑臂或可调节的带子。
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公开(公告)号：USD507832S1
公开(公告)日：2005-07-26
申请号：US29180612
申请日：2003-04-28
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