公开(公告)号：US20140212903A1

公开(公告)日：2014-07-31

申请号：US14226884

申请日：2014-03-27

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Stacy H. Duvall ,  Peter Gebauer ,  Dieter Heindl ,  Carina Horn ,  Peter Kratzsch ,  Michael Marquant ,  Thomas Meier

IPC: C12Q1/54

CPC classification number: C12Q1/54 ,  C07C281/20 ,  C07D295/215

Abstract: Azo compounds are disclosed that do not form azoxy dimers and that do not have any reactive nitroso groups. Also disclosed are use of the azo compounds as mediators in optical and electrochemical diagnostic methods, as well as detection reagents, kits and test elements that include such azo compounds and that can be used in the diagnostic methods.

Abstract translation: 公开了不形成氮氧化二聚体并且不具有任何反应性亚硝基的偶氮化合物。 还公开了在光学和电化学诊断方法中使用偶氮化合物作为介体，以及包括这种偶氮化合物并且可用于诊断方法的检测试剂，试剂盒和测试元件。

公开(公告)号：US08754111B2

公开(公告)日：2014-06-17

申请号：US13945556

申请日：2013-07-18

Applicant: Roche Diagnostics Operations, Inc.

Inventor： Peter Gebauer ,  Dieter Heindl ,  Carina Horn

IPC: C07D213/08 ,  C07D213/14 ,  C07D211/70 ,  C07D211/82 ,  C07D213/46 ,  A01N43/40 ,  A61K31/44 ,  C07C291/00 ,  C07C257/00 ,  C07C263/00 ,  C07C265/00

CPC classification number: C07F9/58 ,  C07C251/12 ,  C07D213/46

Abstract: A method for the synthesis of N-substituted 3-acylated pyridinium compounds by reacting a pentamethine precursor with a primary amine.

Abstract translation: 通过使五甲胺前体与伯胺反应合成N-取代的3-酰化吡啶鎓化合物的方法。