公开(公告)号：US10135359B2

公开(公告)日：2018-11-20

申请号：US15962102

申请日：2018-04-25

申请人： Yang Chen ,  Hongliang Wang ,  Yan-Fei Liu ,  Zhanming Li ,  Yue Fu

发明人： Yang Chen ,  Hongliang Wang ,  Yan-Fei Liu ,  Zhanming Li ,  Yue Fu

IPC分类号： H02M7/219 ,  H02M7/25 ,  H02M7/217 ,  H02M1/42 ,  H02M3/335

摘要： A hybrid rectifier that works as either a hybrid full bridge or a voltage doubler. Under 220 V AC input condition, the hybrid rectifier operates in full bridge mode, while at 110 V AC input, it operates as voltage doubler rectifier. The hybrid rectifier may be used with a DC-DC converter, such as an LLC resonant converter, in a power supply. With this mode switching, the LLC converter resonant tank design only takes consideration of 220 V AC input case, such that the required operational input voltage range is reduced, and the efficiency of the LLC converter is optimized. Both the size and power loss are reduced by using a single stage structure instead of the conventional two-stage configuration.

公开(公告)号：US20180019688A1

公开(公告)日：2018-01-18

申请号：US15547005

申请日：2016-01-29

申请人： Hongliang Wang ,  Yan-Fei Liu

发明人： Hongliang Wang ,  Yan-Fei Liu

IPC分类号： H02M7/797 ,  H02M3/155 ,  H02J3/38

CPC分类号： H02M7/797 ,  H02J3/383 ,  H02M3/155 ,  H02M2001/007 ,  Y02E10/563

摘要： Disclosed are half bridge inverter unit and inverter thereof. The half bridge inverter unit includes an inverter controlling module and inductors. The inverter controlling module provides different connection modes based on different operation modes so that the inverter meets the requirement of wide input voltage range as it can work in either voltage step-up mode or voltage step-down mode. The mid-point voltage between the DC series capacitors connected in parallel with DC power supply can be balanced automatically by taking advantage of the grid voltage symmetry with regard to positive and negative half cycles. The inverter is of single stage structure. It has advantages of low power loss, low cost, high efficiency and reliability.

公开(公告)号：US20140080840A1

公开(公告)日：2014-03-20

申请号：US13991534

申请日：2011-12-06

申请人： Song Li ,  Hongliang Wang ,  Junhai Xiao ,  Xian Zhang ,  Lili Wang ,  Zhibing Zheng ,  Wu Zhong ,  Yunde Xie ,  Xingzhou Li ,  Xinbo Zhou ,  Guoming Zhao ,  Xiaokui Wang

发明人： Song Li ,  Hongliang Wang ,  Junhai Xiao ,  Xian Zhang ,  Lili Wang ,  Zhibing Zheng ,  Wu Zhong ,  Yunde Xie ,  Xingzhou Li ,  Xinbo Zhou ,  Guoming Zhao ,  Xiaokui Wang

IPC分类号： C07D417/04

CPC分类号： C07D417/04 ,  A61K31/496 ,  C07D277/42 ,  Y02A50/465

摘要： Disclosed is as a substituted thiazolamine derivative represented by Formula I or a pharmaceutically acceptable salt thereof or a hydrate thereof (the definitions of each group in the formula are as presented in the description), and the application thereof in the prevention and/or treatment of viral diseases induced by picornavirus. Also disclosed is a pharmaceutical composition containing the compound.

摘要翻译： 公开了作为由式I表示的取代的噻唑胺衍生物或其药学上可接受的盐或其水合物（式中各组的定义如说明书中所述）及其在预防和/或治疗 由小核糖核酸病毒引起的病毒性疾病。 还公开了含有该化合物的药物组合物。

公开(公告)号：US20130190319A1

公开(公告)日：2013-07-25

申请号：US13813806

申请日：2011-08-02

申请人： Song Li ,  Hongliang Wang ,  Junhai Xiao ,  Xian Zhang ,  Lili Wang ,  Zhibing Zheng ,  Wu Zhong ,  Yunde Xie ,  Xingzhou Li ,  Xinbo Zhou ,  Guoming Zhao ,  Xiaokui Wang

发明人： Song Li ,  Hongliang Wang ,  Junhai Xiao ,  Xian Zhang ,  Lili Wang ,  Zhibing Zheng ,  Wu Zhong ,  Yunde Xie ,  Xingzhou Li ,  Xinbo Zhou ,  Guoming Zhao ,  Xiaokui Wang

IPC分类号： C07D237/20

CPC分类号： C07D237/20

摘要： Disclosed are pyridazine derivatives represented by Formula I or pharmaceutically acceptable salts or hydrates thereof, pharmaceutical compositions comprising the compounds, methods of treating and/or preventing diseases or disorders associated with viral infections in patients using the compounds, and the use of the compounds in preparing the medicaments for treating and/or preventing diseases or disorders associated with viral infections. The compounds represented by Formula I have antiviral activity, especially anti-microRNA viral activity. Symbols in the compounds represented are described in the specification.