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公开(公告)号:US08945556B2
公开(公告)日:2015-02-03
申请号:US13300063
申请日:2011-11-18
IPC分类号: A61K39/395 , C12Q1/68
CPC分类号: C12Q1/6886 , C12N9/12 , C12Q2600/156 , C12Q2600/158 , C12Y207/11001 , G01N33/5748 , G01N2333/912 , G01N2333/91205
摘要: The present disclosure relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present disclosure relates to RAF gene fusions as diagnostic markers and clinical targets for cancer.
摘要翻译: 本公开涉及用于癌症诊断,研究和治疗的组合物和方法,包括但不限于癌症标志物。 特别地,本公开涉及作为诊断标志物和癌症临床靶标的RAF基因融合体。
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公开(公告)号:US07597890B2
公开(公告)日:2009-10-06
申请号:US11715642
申请日:2007-03-08
申请人: Arul Chinnaiyan , David Beer , Guoan Chen , Xiaoju Wang
发明人: Arul Chinnaiyan , David Beer , Guoan Chen , Xiaoju Wang
IPC分类号: A61K39/395
CPC分类号: C12N15/1037 , C07K14/4748 , C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/136 , G01N33/57415 , G01N33/57423 , G01N33/57434 , G01N33/6845
摘要: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ubiquilin 1 markers for cancer.
摘要翻译: 本发明涉及用于癌症诊断,研究和治疗的组合物和方法,包括但不限于癌症标志物。 特别地,本发明涉及用于癌症的泛素标记1。
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公开(公告)号:US20070128639A1
公开(公告)日:2007-06-07
申请号:US11592087
申请日:2006-11-02
IPC分类号: C12Q1/68 , G01N33/574
CPC分类号: G01N33/57434 , C12Q1/6886 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , G01N33/574
摘要: The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides cancer markers useful in the diagnosis and characterization of prostate and breast cancers.
摘要翻译: 本发明涉及用于癌症诊断的组合物和方法,包括但不限于癌症标志物。 特别地,本发明提供了可用于诊断和鉴定前列腺癌和乳腺癌的癌症标志物。
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公开(公告)号:US20050230315A1
公开(公告)日:2005-10-20
申请号:US11094590
申请日:2005-03-30
申请人: David Lubman , Arul Chinnaiyan , Manoj Pal , Arun Sreekumar , Stephen Ethier
发明人: David Lubman , Arul Chinnaiyan , Manoj Pal , Arun Sreekumar , Stephen Ethier
CPC分类号: C07K1/047 , C07K1/1077 , G01N30/02 , G01N33/6842 , B01D15/325
摘要: The present invention relates to automated methods, systems, and apparatuses for protein separation and analysis. In particular, the present invention provides an automated system for the separation, identification, and characterization of the phosphorylation status of protein samples, including the generation and analysis of protein microarrays.
摘要翻译: 本发明涉及用于蛋白质分离和分析的自动化方法,系统和装置。 特别地,本发明提供了用于蛋白质样品的磷酸化状态的分离,鉴定和表征的自动化系统,包括蛋白质微阵列的产生和分析。
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公开(公告)号:US20130267443A1
公开(公告)日:2013-10-10
申请号:US13797106
申请日:2013-03-12
申请人: Arul Chinnaiyan , John Prensner , Matthew Iyer
发明人: Arul Chinnaiyan , John Prensner , Matthew Iyer
IPC分类号: C12Q1/68
CPC分类号: C12Q1/6886 , A61K31/4184 , C12Q2600/106 , C12Q2600/112 , C12Q2600/118 , C12Q2600/136 , C12Q2600/158
摘要: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ncRNAs as diagnostic markers and clinical targets for prostate, lung, breast and pancreatic cancer.
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公开(公告)号:US07858323B2
公开(公告)日:2010-12-28
申请号:US11145861
申请日:2005-06-06
申请人: Arul Chinnaiyan , Xiaoju Wang
发明人: Arul Chinnaiyan , Xiaoju Wang
CPC分类号: C12N15/1037 , C07K14/4748 , C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/136 , G01N33/57415 , G01N33/57423 , G01N33/57434 , G01N33/6845
摘要: The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides methods and compositions for phage microarray profiling of cancer (e.g., prostate, lung, or breast cancer). The present invention further provides novel markers useful for the diagnosis, characterization, and treatment of cancers.
摘要翻译: 本发明涉及用于癌症诊断的组合物和方法,包括但不限于癌症标志物。 特别地,本发明提供了用于癌症(例如前列腺,肺或乳腺癌)的噬菌体微阵列分析的方法和组合物。 本发明还提供了可用于诊断,表征和治疗癌症的新型标志物。
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公开(公告)号:US20080044839A1
公开(公告)日:2008-02-21
申请号:US11715642
申请日:2007-03-08
申请人: Arul Chinnaiyan , David Beer , Guoan Chen , Xiaoju Wang
发明人: Arul Chinnaiyan , David Beer , Guoan Chen , Xiaoju Wang
IPC分类号: G01N33/53
CPC分类号: C12N15/1037 , C07K14/4748 , C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/136 , G01N33/57415 , G01N33/57423 , G01N33/57434 , G01N33/6845
摘要: The present invention relates to compositions and methods for cancer diagnosis, research and therapy, including but not limited to, cancer markers. In particular, the present invention relates to ubiquilin 1 markers for cancer.
摘要翻译: 本发明涉及用于癌症诊断,研究和治疗的组合物和方法,包括但不限于癌症标志物。 特别地,本发明涉及用于癌症的泛素标记1。
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公开(公告)号:US20060014138A1
公开(公告)日:2006-01-19
申请号:US11145861
申请日:2005-06-06
申请人: Arul Chinnaiyan , Xiaoju Wang
发明人: Arul Chinnaiyan , Xiaoju Wang
CPC分类号: C12N15/1037 , C07K14/4748 , C12Q1/6886 , C12Q2600/106 , C12Q2600/118 , C12Q2600/136 , G01N33/57415 , G01N33/57423 , G01N33/57434 , G01N33/6845
摘要: The present invention relates to compositions and methods for cancer diagnostics, including but not limited to, cancer markers. In particular, the present invention provides methods and compositions for phage microarray profiling of cancer (e.g., prostate, lung, or breast cancer). The present invention further provides novel markers useful for the diagnosis, characterization, and treatment of cancers.
摘要翻译: 本发明涉及用于癌症诊断的组合物和方法,包括但不限于癌症标志物。 特别地,本发明提供了用于癌症(例如前列腺,肺或乳腺癌)的噬菌体微阵列分析的方法和组合物。 本发明还提供了可用于诊断,表征和治疗癌症的新型标志物。
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