System and method for real-time MRI-guided object navigation

    公开(公告)号:US10548505B2

    公开(公告)日:2020-02-04

    申请号:US15070116

    申请日:2016-03-15

    IPC分类号: A61B5/055

    摘要: A magnetic resonance method and system are provided for magnetic resonance (MR) image-guided insertion of an object into a biological tissue along a predetermined trajectory. The trajectory provides a path between a starting point and a target site within the tissue. Sufficiently high resolution images can be generated in real time to precisely guide the needle placement. A compressed sensing approach is used to generate the images based on minimization of a cost function, where the cost function is based on the predetermined needle path, artifact effects associated with the needle, the negligible changes in the images away from the trajectory, and the limited differences between successive images. The improved combination of spatial and temporal resolution facilitates an insertion procedure that can be continuously adjusted to accurately follow a predetermined trajectory in the tissue, without interruptions to obtain verification images.

    METHOD AND DEVICE FOR DETERMINING A CHANGE OVER TIME IN A BIOMARKER IN A REGION TO BE EXAMINED

    公开(公告)号:US20190271751A1

    公开(公告)日:2019-09-05

    申请号:US16418187

    申请日:2019-05-21

    摘要: A method for determining a change over time in a biomarker in a region to be examined of a patient is provided. The change is determined from magnetic resonance data using a magnetic resonance measuring system with sequences and protocols for measuring the biomarkers by functional resting state connectivity by rsfMRI, perfusion values, magnetic resonance spectra of voxels, or morphometry of organs. A control unit has programs which evaluates the biomarker and a data memory which stores the results of the evaluation and additional data. During a first examination, a quantity result of the biomarkers is determined and stored in the data memory. During a follow-up examination, at least one previous item of the result and additional data from the first examination stored in the data memory are used for determining a quantitative change in the biomarker.

    METHOD AND APPARATUS FOR IDENTIFYING AN ORGAN STRUCTURE OF AN EXAMINED OBJECT IN MAGNETIC RESONANCE IMAGE DATA

    公开(公告)号:US20180153431A1

    公开(公告)日:2018-06-07

    申请号:US15370062

    申请日:2016-12-06

    IPC分类号: A61B5/055 A61B5/00

    摘要: In a method and apparatus for identifying an organ structure of an examined object in magnetic resonance image data, magnetic resonance measurement data for the organ structure of the examined object are acquired by operation of a magnetic resonance scanner using a magnetic resonance sequence that specifies a sampling scheme of k-space. Magnetic resonance image data are reconstructed from the magnetic resonance measurement data. The organ structure is identified in the magnetic resonance image data. The sampling scheme of k-space is selected so as to support the subsequent identification of the organ structure in the magnetic resonance image data reconstructed from the magnetic resonance measurement data.