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公开(公告)号:US20060098006A1
公开(公告)日:2006-05-11
申请号:US11230803
申请日:2005-09-20
申请人: Stefan Bohm , Sandra Martin
发明人: Stefan Bohm , Sandra Martin
CPC分类号: H04N5/325
摘要: The present invention relates to a method for image reproduction, in particular for single or serial medical exposures, whereby one or more main images are reproduced on a display device. The method is characterized in that additional or interim images are generated using image interpolation prior to image reproduction from the one or more main images and in that additional image noise which varies from image to image is applied to the one or more main images and the additional or interim images, said image noise being generated by a noise generator, and image reproduction taking place by displaying in chronological order the one or more main images and additional or interim images to which the additional image noise has been applied. The method in particular improves the visual image impression in the case of fluoroscopic X-ray image exposures, without having to in-crease the applied X-ray dose.
摘要翻译: 本发明涉及一种用于图像再现的方法,特别是用于单次或连续医疗照射,其中在显示装置上再现一个或多个主图像。 该方法的特征在于,使用来自一个或多个主图像的图像再现之前的图像插值来生成附加或中间图像,并且从图像到图像变化的附加图像噪声被应用于一个或多个主图像和附加 或临时图像,所述图像噪声由噪声发生器产生,并且通过按照时间顺序显示已应用附加图像噪声的一个或多个主图像和附加或临时图像来进行图像再现。 该方法特别地改善了在透视X射线图像曝光的情况下的视觉图像印象,而不必减少施加的X射线剂量。
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公开(公告)号:US5863933A
公开(公告)日:1999-01-26
申请号:US822565
申请日:1997-03-19
申请人: Winfried Lunkenheimer , Bernd Baasner , Folker Lieb , Stefan Bohm , Albrecht Marhold , Ulrich Gorgens , Wilhelm Stendel , Heinz-Wilhelm Dehne , Hans-Joachim Santel
发明人: Winfried Lunkenheimer , Bernd Baasner , Folker Lieb , Stefan Bohm , Albrecht Marhold , Ulrich Gorgens , Wilhelm Stendel , Heinz-Wilhelm Dehne , Hans-Joachim Santel
IPC分类号: A01N43/52 , A01N43/90 , A01N47/12 , A01N47/18 , A01N47/20 , A01N47/30 , A01N47/34 , A01N57/24 , C07D235/10 , C07D405/12 , C07D491/04 , C07D491/056 , C07F9/6506
CPC分类号: C07D405/12 , A01N43/52 , A01N43/90 , A01N47/12 , A01N47/18 , A01N47/20 , A01N47/30 , A01N47/34 , C07D235/10 , C07D491/04 , C07F9/65068
摘要: The invention relates to new substituted benzimidazole of the general formula (I) ##STR1## in which R.sup.1 represents hydrogen, alkyl, alkoxy or optionally substituted aryl,R.sup.2 represents hydroxyl, cyano or in each case optionally substituted alkyl, alkenyl, alkinyl, alkoxy, alkenyloxy, alkinyloxy, alkylthio, amino, aminocarbonyl, alkylcarbonyl, alkoxycarbonyl, alkoxycarbonyloxy, dialkoxyphosphonyl, (hetero)aryl, (hetero)arylcarbonyl, (hetero)aryloxycarbonyl, (hetero)arylcarbonyloxy or (hetero)arylaminocarbonylaminocarbonyloxy, andR.sup.3 represents fluoroalkyl,X.sup.1, X.sup.2, X.sup.3 and X.sup.4 independently of one another in each case represent hydrogen, halogen, cyano, nitro, in each case optionally substituted alkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl or cycloalkyl, optionally substituted, fused dioxyalkylene, or represent hydroxycarbonyl, alkylcarbonyl, alkoxycarbonyl or cycloalkyloxycarbonyl, in each case optionally substituted amino or aminocarbonyl or in each case optionally substituted aryl, aryloxy, arylthio, arylsulphinyl, arylsulphonyl, arylsulphonyloxy, arylcarbonyl, aryloxycarbonyl, arylazo or arylthiomethylsulphonyl, but where at least one of the substituents X.sup.1, X.sup.2, X.sup.3 or X.sup.4 represents halogenoalkyl, with the exception of the chloromethyl radical, halogenoalkoxy, halogenoalkylthio, halogenoalkylsulphinyl, halogenoalkylsulphonyl or alkylsulphonyl, optionally substituted, fused dioxyalkylene, or represent hydroxycarbonyl, alkylcarbonyl, alkoxycarbonyl or cycloalkyloxycarbonyl, in each case optionally substituted amino or aminocarbonyl, or in each case optionally substituted aryl, arylthio, arylsulphinyl, arylsulphonyl, arylsulphonyloxy, arylcarbonyl, aryloxycarbonyl, arylazo or arylthiomethylsulphonyl,their preparation and use as pesticides, and intermediates for their preparation.
摘要翻译: 本发明涉及通式(I)的新取代的苯并咪唑,其中R 1表示氢,烷基,烷氧基或任选取代的芳基,R 2表示羟基,氰基或在各种情况下任选取代的烷基,烯基,炔基 (杂)芳基羰基,(杂)芳基羰基氧基或(杂)芳基氨基羰基氨基羰基氧基,R3代表氟代烷基,芳基羰氧基, 在各种情况下,X1,X2,X3和X4彼此独立地表示氢,卤素,氰基,硝基,在各种情况下均为任选取代的烷基,烷氧基,烷硫基,烷基亚磺酰基,烷基磺酰基或环烷基,任选取代的稠合二氧亚烷基,或代表羟基羰基 ,烷基羰基,烷氧基羰基或环烷氧基羰基,在每种情况下均为任选取代的氨基或氨基羰基,或在每种情况下任选取代 芳基,芳氧基,芳硫基,芳基亚磺酰基,芳基磺酰基,芳基磺酰氧基,芳基羰基,芳氧基羰基,芳基偶氮或芳基硫代甲基磺酰基,但其中至少一个取代基X1,X2,X3或X4表示卤代烷基,除了氯甲基,卤代烷氧基,卤代烷硫基 ,卤代烷基亚磺酰基,卤代烷基磺酰基或烷基磺酰基,任选取代的稠合的二氧亚烷基,或代表羟基羰基,烷基羰基,烷氧基羰基或环烷氧基羰基,在各种情况下均为任选取代的氨基或氨基羰基,或在每种情况下均为任选取代的芳基,芳硫基,芳基亚磺酰基,芳基磺酰基,芳基磺酰氧基,芳基羰基, 芳氧基羰基,芳基偶氮或芳基硫代甲基磺酰基,它们的制备和用作农药,以及其制备中间体。
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公开(公告)号:US5780394A
公开(公告)日:1998-07-14
申请号:US788715
申请日:1997-01-23
申请人: Bernd-Wieland Kruger , Reiner Fischer , Heinz-Jurgen Bertram , Thomas Bretschneider , Stefan Bohm , Andreas Krebs , Thomas Schenke , Hans-Joachim Santel , Klaus Lurssen , Robert R. Schmidt , Christoph Erdelen , Ulrike Wachendorff-Neumann , Wilhelm Stendel
发明人: Bernd-Wieland Kruger , Reiner Fischer , Heinz-Jurgen Bertram , Thomas Bretschneider , Stefan Bohm , Andreas Krebs , Thomas Schenke , Hans-Joachim Santel , Klaus Lurssen , Robert R. Schmidt , Christoph Erdelen , Ulrike Wachendorff-Neumann , Wilhelm Stendel
IPC分类号: A01N43/56 , A01N43/90 , A01N47/06 , A01N47/18 , A01N57/16 , C07D231/32 , C07D487/04 , C07D487/08
CPC分类号: C07D487/04 , A01N43/56 , A01N43/90 , A01N47/06 , A01N47/18 , A01N57/16 , C07D231/32 , C07D487/08
摘要: There are provided new 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives of the formula (I) ##STR1## in which A and B are identical or different and independently of one another in each case represent hydrogen, alkyl, alkenyl, alkynyl, alkoxyalkyl, alkylthioalkyl, cycloalkyl or optionally substituted aryl or A and B together represent the bivalent radical of a saturated or unsaturated, optionally substituted, mono-, bi-, tri- or polycyclic system, X represents alkyl, halogen or alkoxy, Y represents hydrogen, alkyl, halogen, alkoxy or halogenoalkyl, Z represents alkyl, halogen or alkoxy n represents a number 0, 1, 2 or 3, G represents hydrogen (a) or the groups ##STR2## in which E represents a metal ion equivalent or an ammonium ion, L and M represents oxygen and/or sulphur, and R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5, R.sup.6 and R.sup.7 have the meaning given in the text of the application. The new 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives of the formula (I) have a particularly pronounced activity against animal pests, in particular against insects and arachnids, and against weeds.
摘要翻译: 提供了式(I)的新的3-羟基-4-芳基-5-氧代 - 吡唑啉衍生物,其中A和B相同或不同,并且在每种情况下彼此独立地表示氢, 烷基,烯基,炔基,烷氧基烷基,烷硫基烷基,环烷基或任选取代的芳基或A和B一起表示饱和或不饱和的任选取代的单,双,三或多环体系的二价基团,X表示烷基,卤素 或烷氧基,Y表示氢,烷基,卤素,烷氧基或卤代烷基,Z表示烷基,卤素或烷氧基,n表示数字0,1,2或3,G表示氢(a)或基团COR1,(b)
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公开(公告)号:US5661110A
公开(公告)日:1997-08-26
申请号:US476171
申请日:1995-06-07
申请人: Bernd-Wieland Kruger , Reiner Fischer , Heinz-Jurgen Bertram , Thomas Bretschneider , Stefan Bohm , Andreas Krebs , Thomas Schenke , Hans-Joachim Santel , Klaus Lurssen , Robert R. Schmidt , Christoph Erdelen , Ulrike Wachendorff-Neumann , Wilhelm Stendel
发明人: Bernd-Wieland Kruger , Reiner Fischer , Heinz-Jurgen Bertram , Thomas Bretschneider , Stefan Bohm , Andreas Krebs , Thomas Schenke , Hans-Joachim Santel , Klaus Lurssen , Robert R. Schmidt , Christoph Erdelen , Ulrike Wachendorff-Neumann , Wilhelm Stendel
IPC分类号: A01N43/56 , A01N43/90 , A01N47/06 , A01N47/18 , A01N57/16 , C07D231/32 , C07D487/04 , C07D487/08 , C07D231/54
CPC分类号: C07D487/04 , A01N43/56 , A01N43/90 , A01N47/06 , A01N47/18 , A01N57/16 , C07D231/32 , C07D487/08
摘要: There are provided new 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives of the formula (I) ##STR1## The new 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives of the formula (I) have a particularly pronounced activity against animal pests, in particular against insects and arachnids, and against weeds.
摘要翻译: 提供式(I)的新的3-羟基-4-芳基-5-氧代 - 吡唑啉衍生物(I)将新的3-羟基-4-芳基-5-氧代 - 吡唑啉衍生物(式 I)对动物害虫,特别是针对昆虫和蜘蛛,以及针对杂草具有特别明显的活性。
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公开(公告)号:US5656649A
公开(公告)日:1997-08-12
申请号:US428087
申请日:1995-05-25
申请人: Winfried Lunkenheimer , Bernd Baasner , Folker Lieb , Stefan Bohm , Albrecht Marhold , Ulrich Gorgens , Wilhelm Stendel , Heinz-Wilhelm Dehne , Hans-Joachim Santel
发明人: Winfried Lunkenheimer , Bernd Baasner , Folker Lieb , Stefan Bohm , Albrecht Marhold , Ulrich Gorgens , Wilhelm Stendel , Heinz-Wilhelm Dehne , Hans-Joachim Santel
IPC分类号: A01N43/52 , A01N43/90 , A01N47/12 , A01N47/18 , A01N47/20 , A01N47/30 , A01N47/34 , A01N57/24 , C07D235/10 , C07D405/12 , C07D491/04 , C07D491/056 , C07F9/6506
CPC分类号: C07D405/12 , A01N43/52 , A01N43/90 , A01N47/12 , A01N47/18 , A01N47/20 , A01N47/30 , A01N47/34 , C07D235/10 , C07D491/04 , C07F9/65068
摘要: The invention relates to new substituted benzimidazoles of the general formula (I) ##STR1## in which R.sup.1 represents hydrogen, alkyl, alkoxy or optionally substituted aryl,R.sup.2 represents hydroxyl, cyano or in each case optionally substituted alkyl, alkenyl, alkinyl, alkoxy, alkenyloxy, alkinyloxy, alkylthio, amino, aminocarbonyl, alkylcarbonyl, alkoxycarbonyl, alkylcarbonyloxy, dialkoxyphosphonyl, (hetero)aryl, (hetero)arylcarbonyl, (hetero)aryloxycarbonyl, (hetero)arylcarbonyloxy or (hetero)arylaminocarbonylaminocarbonyloxy, andR.sup.3 represents fluoroalkyl,X.sup.1, X.sup.2, X.sup.3 and X.sup.4 independently of one another in each case represent hydrogen, halogen, cyano, nitro, in each case optionally substituted alkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl or cycloalkyl, optionally substituted, fused dioxyalkylene, or represent hydroxycarbonyl, alkylcarbonyl, alkoxycarbonyl or cycloalkyloxycarbonyl, in each case optionally substituted amino or aminocarbonyl or in each case optionally substituted aryl, aryloxy, arylthio, arylsulphinyl, arylsulphonyl, arylsulphonyloxy, arylcarbonyl, aryloxycarbonyl, arylazo or arylthiomethylsulphonyl, but where at least one of the substituents X.sup.1, X.sup.2, X.sup.3 or X.sup.4 represents halogenoalkyl, with the exception of the chloromethyl radical, halogenoalkoxy, halogenoalkylthio, halogenoalkylsulphinyl, halogenoalkylsulphonyl or alkylsulphonyl, optionally substituted, fused dioxyalkylene, or represent hydroxycarbonyl, alkylcarbonyl, alkoxycarbonyl or cycloalkyloxycarbonyl, in each case optionally substituted amino or aminocarbonyl, or in each case optionally substituted aryl, arylthio, arylsulphinyl, arylsulphonyl, arylsulphonyloxy, arylcarbonyl, aryloxycarbonyl, arylazo or arylthiomethylsulphonyl,their preparation and use as pesticides, and intermediates for their preparation.
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公开(公告)号:US5530149A
公开(公告)日:1996-06-25
申请号:US462730
申请日:1995-06-05
申请人: Jurgen Scherkenbeck , Thomas Himmler , Stefan Bohm , Hermann Hagemann , Klaus Stroech , Stefan Dutzmann , Heinz-Wilhelm Dehne , Gerd Hanssler
发明人: Jurgen Scherkenbeck , Thomas Himmler , Stefan Bohm , Hermann Hagemann , Klaus Stroech , Stefan Dutzmann , Heinz-Wilhelm Dehne , Gerd Hanssler
IPC分类号: A01N43/653 , C07D249/08 , C07D301/02 , C07D303/08 , C07D303/18 , C07D303/20 , C07D521/00
CPC分类号: C07D249/08 , A01N43/653 , C07D231/12 , C07D233/56
摘要: New azolylmethyl-fluorocyclopropyl derivatives of the formula ##STR1## in which R represents ##STR2## and addition products thereof which acids or metal salts are very effective for combating fungi.New oxiranes of the formula ##STR3## in which R has the abovementioned meaning, are valuable intermediates for the preparation of compounds of the formula (I).
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公开(公告)号:US5474974A
公开(公告)日:1995-12-12
申请号:US233911
申请日:1994-04-28
申请人: Bernd-Wieland Kruger , Reiner Fischer , Heinz-Jurgen Bertram , Thomas Bretschneider , Stefan Bohm , Andreas Krebs , Thomas Schenke , Hans-Joachim Santel , Klaus Lurssen , Robert R. Schmidt , Christoph Erdelen , Ulrike Wachendorff-Neumann , Wilhelm Stendel
发明人: Bernd-Wieland Kruger , Reiner Fischer , Heinz-Jurgen Bertram , Thomas Bretschneider , Stefan Bohm , Andreas Krebs , Thomas Schenke , Hans-Joachim Santel , Klaus Lurssen , Robert R. Schmidt , Christoph Erdelen , Ulrike Wachendorff-Neumann , Wilhelm Stendel
IPC分类号: A01N43/56 , A01N43/90 , A01N47/06 , A01N47/18 , A01N57/16 , C07D231/32 , C07D487/04 , C07D487/08 , A01N43/58
CPC分类号: C07D487/04 , A01N43/56 , A01N43/90 , A01N47/06 , A01N47/18 , A01N57/16 , C07D231/32 , C07D487/08
摘要: There are provided new 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives of the formula (I) ##STR1## The new 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives of the formula (I) have a particularly pronounced activity against animal pests, in particular against insects and arachnids, and against weeds.
摘要翻译: 提供式(I)的新的3-羟基-4-芳基-5-氧代 - 吡唑啉衍生物(I)将新的3-羟基-4-芳基-5-氧代 - 吡唑啉衍生物(式 I)对动物害虫,特别是针对昆虫和蜘蛛,以及针对杂草具有特别明显的活性。
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28.
公开(公告)号:US5434303A
公开(公告)日:1995-07-18
申请号:US158080
申请日:1993-11-24
申请人: Stefan Bohm , Albrecht Marhold
发明人: Stefan Bohm , Albrecht Marhold
摘要: A new process for the preparation of 1-fluoro-cyclopropane-1-carboxylic acid of the formula ##STR1## which process comprises a) reacting in a first step, a 1-fluoro-cyclopropyl phenyl ketone of the formula ##STR2## in which R represents hydrogen, halogen, methyl, methoxy, phenyl or phenoxy,with an peroxy compound in the presence of a diluent, andb) reacting, in a second step, the resulting 1-fluoro-cyclopropane-1-carboxylate of the formula ##STR3## in which R has the abovementioned meaning,with a base in the presence of a diluent, and then acidifying the mixture.New 1-fluoro-cyclopropane-1-carboxylates of the above-mentioned formula.
摘要翻译: 用于制备下式的“1-氟 - 环丙烷-1-羧酸”的新方法该方法包括:a)在第一步骤中,使式“IMAGE”的1-氟 - 环丙基苯基酮反应,其中 R表示氢,卤素,甲基,甲氧基,苯基或苯氧基,在稀释剂存在下与过氧化合物反应,和b)在第二步中,使得到的所述1-氟 - 环丙烷-1-羧酸酯 IMAGE>其中R具有上述含义,用碱在稀释剂存在下,然后酸化混合物。 上述式的新的1-氟 - 环丙烷-1-羧酸酯。
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公开(公告)号:US5332720A
公开(公告)日:1994-07-26
申请号:US968888
申请日:1992-12-16
申请人: Bernd-Wieland Kruger , Reiner Fischer , Heinz-Jurgen Bertram , Thomas Bretschneider , Stefan Bohm , Andreas Krebs , Thomas Schenke , Hans-Joachim Santel , Klaus Lurssen , Robert R. Schmidt , Christoph Erdelen , Ulrike Wachendorff-Neumann , Wilhelm Stendel
发明人: Bernd-Wieland Kruger , Reiner Fischer , Heinz-Jurgen Bertram , Thomas Bretschneider , Stefan Bohm , Andreas Krebs , Thomas Schenke , Hans-Joachim Santel , Klaus Lurssen , Robert R. Schmidt , Christoph Erdelen , Ulrike Wachendorff-Neumann , Wilhelm Stendel
IPC分类号: A01N43/56 , A01N43/90 , A01N47/06 , A01N47/18 , A01N57/16 , C07D231/32 , C07D231/34 , C07D231/36 , C07D487/04 , C07D487/08 , C07F9/6503 , C07F9/6561 , C07D231/54
CPC分类号: C07D487/04 , A01N43/56 , A01N43/90 , A01N47/06 , A01N47/18 , A01N57/16 , C07D231/32 , C07D487/08
摘要: There are provided new 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives of the formula (I) ##STR1## The new 3-hydroxy-4-aryl-5-oxo-pyrazoline derivatives of the formula (I) have a particularly pronounced activity against animal pests, in particular against insects and arachnids, and against weeds.
摘要翻译: 提供式(I)的新的3-羟基-4-芳基-5-氧代 - 吡唑啉衍生物(I)将新的3-羟基-4-芳基-5-氧代 - 吡唑啉衍生物(式 I)对动物害虫,特别是针对昆虫和蜘蛛,以及针对杂草具有特别明显的活性。
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30.
公开(公告)号:US5223643A
公开(公告)日:1993-06-29
申请号:US789214
申请日:1991-11-07
IPC分类号: B01J31/02 , C07B61/00 , C07C313/08 , C07C319/18 , C07C323/03
CPC分类号: C07C319/18 , C07C313/08
摘要: The present invention relates to a multi-step process for the preparation of 1,1-difluoroalkanesulphenyl chlorides of the general formula (I):R--CH.sub.2 --CF.sub.2 --S--ClThe process comprises the following steps:(1) R.sup.1 --SH+R--CH.dbd.CF.sub.2 .fwdarw.R.sup.1 --S--CF.sub.2 --CH.sub.2 --R(2) R.sup.1 --S--CF.sub.2 --CH.sub.2 --R+chlorine agent.fwdarw.Cl--S--CF.sub.2 --CH.sub.2 --RStep (1) is carried out in a base at 0.degree. C.-250.degree. C., optionally in the presence of a solvent and/or a phase transfer catalyst. Step (2) is carried out at -78.degree. C.-100.degree. C., optionally in a solvent and optionally after the product of step (1) has been isolated. The final products are intermediates for organic syntheses.
摘要翻译: 本发明涉及制备通式(I)的1,1-二氟链烷基苯氯化物的多步法:R-CH2-CF2-S-C1该方法包括以下步骤:(1)R1-SH + R-CH = CF2-> R1-S-CF2-CH2-R(2)R1-S-CF2-CH2-R +氯剂 - > Cl-S-CF2-CH2-R步骤(1) 在0℃-250℃的碱中,任选地在溶剂和/或相转移催化剂存在下进行。 步骤(2)在-78℃-100℃,任选地在溶剂中,任选地在步骤(1)的产物已经分离后进行。 最终产品是有机合成的中间体。
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