公开(公告)号：US10053468B2

公开(公告)日：2018-08-21

申请号：US14902309

申请日：2014-07-02

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Satoshi Yamamoto ,  Junya Shirai ,  Hiroyuki Watanabe ,  Shoji Fukumoto ,  Tsuneo Oda ,  Hidekazu Tokuhara ,  Yoshihide Tomata ,  Naoki Ishii ,  Michiko Tawada ,  Mitsunori Kono ,  Atsuko Ochida ,  Takashi Imada ,  Yoshiyuki Fukase ,  Tomoya Yukawa

IPC: C07D491/056 ,  C07D217/26 ,  C07D401/06 ,  C07D405/06 ,  C07D409/06 ,  C07D413/06 ,  C07D417/06 ,  C07D471/04 ,  C07D491/048 ,  C07D401/12 ,  C07D413/12 ,  C07D491/04 ,  C07D413/14 ,  C07D401/04 ,  C07D405/12 ,  C07F7/08

CPC classification number: C07D491/056 ,  C07D217/26 ,  C07D401/04 ,  C07D401/06 ,  C07D401/12 ,  C07D405/06 ,  C07D405/12 ,  C07D409/06 ,  C07D413/06 ,  C07D413/12 ,  C07D413/14 ,  C07D417/06 ,  C07D471/04 ,  C07D491/04 ,  C07D491/048 ,  C07F7/0812

Abstract: The present invention relates to compound (I) or a salt thereof which has a RORγt inhibitory action. wherein each symbol is as defined in the specification.

公开(公告)号：US09650343B2

公开(公告)日：2017-05-16

申请号：US15055156

申请日：2016-02-26

Applicant: Takeda Pharmaceutical Company Limited

Inventor： Satoshi Yamamoto ,  Junya Shirai ,  Tsuneo Oda ,  Mitsunori Kono ,  Atsuko Ochida ,  Takashi Imada ,  Hidekazu Tokuhara ,  Yoshihide Tomata ,  Naoki Ishii ,  Michiko Tawada ,  Yoshiyuki Fukase ,  Tomoya Yukawa ,  Shoji Fukumoto

IPC: C07D471/04 ,  C07D215/00 ,  C07D217/26 ,  C07F7/08 ,  C07D491/048 ,  C07D491/056 ,  A61K31/4375 ,  A61K31/472 ,  A61K31/4741 ,  C07D217/14 ,  C07D491/14

CPC classification number: C07D217/26 ,  A61K31/4375 ,  A61K31/472 ,  A61K31/4741 ,  C07D217/14 ,  C07D471/04 ,  C07D491/048 ,  C07D491/056 ,  C07D491/14 ,  C07F7/0812

Abstract: The present invention provides a heterocyclic compound having a RORγt inhibitory action.The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.

公开(公告)号：US20170107240A1

公开(公告)日：2017-04-20

申请号：US14902388

申请日：2014-07-02

Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED

Inventor： Satoshi Yamamoto ,  Junya Shirai ,  Mitsunori Kono ,  Yoshihide Tomata ,  Ayumu Sato ,  Atsuko Ochida ,  Yoshiyuki Fukase ,  Shoji Fukumoto ,  Tsuneo Oda ,  Hidekazu Tokuhara ,  Naoki Ishii ,  Yusuke Sasaki

IPC: C07F7/08 ,  C07D205/04 ,  C07D207/12 ,  C07K5/065 ,  C07K5/087

Abstract: The present invention relates to compound (I) or a salt thereof which has a RORγt inhibitory action. In the formula (I), each symbol is as defined in the specification.

公开(公告)号：US09573903B2

公开(公告)日：2017-02-21

申请号：US15055197

申请日：2016-02-26

Applicant: Takeda Pharmaceutical Company Limited

Inventor： Satoshi Yamamoto ,  Junya Shirai ,  Tsuneo Oda ,  Mitsunori Kono ,  Atsuko Ochida ,  Takashi Imada ,  Hidekazu Tokuhara ,  Yoshihide Tomata ,  Naoki Ishii ,  Michiko Tawada ,  Yoshiyuki Fukase ,  Tomoya Yukawa ,  Shoji Fukumoto

IPC: C07D471/04 ,  C07D215/00 ,  C07D217/26 ,  C07F7/08 ,  C07D491/048 ,  C07D491/056 ,  A61K31/4375 ,  A61K31/472 ,  A61K31/4741 ,  C07D217/14 ,  C07D491/14

CPC classification number: C07D217/26 ,  A61K31/4375 ,  A61K31/472 ,  A61K31/4741 ,  C07D217/14 ,  C07D471/04 ,  C07D491/048 ,  C07D491/056 ,  C07D491/14 ,  C07F7/0812

Abstract: The present invention provides a heterocyclic compound having a RORγt inhibitory action.The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.

Abstract translation: 本发明提供具有RORγt抑制作用的杂环化合物。 本发明涉及由式（I）表示的化合物：其中每个符号如说明书中所定义。 或其盐。