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公开(公告)号：US09630924B2
公开(公告)日：2017-04-25
申请号：US15055108
申请日：2016-02-26
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Satoshi Yamamoto , Junya Shirai , Tsuneo Oda , Mitsunori Kono , Atsuko Ochida , Takashi Imada , Hidekazu Tokuhara , Yoshihide Tomata , Naoki Ishii , Michiko Tawada , Yoshiyuki Fukase , Tomoya Yukawa , Shoji Fukumoto
IPC: C07D471/04 , C07D215/00 , C07D217/26 , C07F7/08 , C07D491/048 , C07D491/056 , A61K31/4375 , A61K31/472 , A61K31/4741 , C07D217/14 , C07D491/14
CPC classification number: C07D217/26 , A61K31/4375 , A61K31/472 , A61K31/4741 , C07D217/14 , C07D471/04 , C07D491/048 , C07D491/056 , C07D491/14 , C07F7/0812
Abstract: The present invention provides a heterocyclic compound having a RORγt inhibitory action.The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.
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公开(公告)号：US10301292B2
公开(公告)日：2019-05-28
申请号：US15529816
申请日：2015-11-25
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Ryo Mizojiri , Hiroshi Banno , Moriteru Asano , Daisuke Tomita , Noriyuki Nii , Hironobu Maezaki , Michiko Tawada
IPC: C07D413/04 , C07D413/14 , A61K31/343 , A61K31/381 , A61K31/416 , A61K31/423 , A61K31/428 , A61K31/437 , A61K31/443 , A61K31/4439 , A61K31/497 , A61K31/501 , A61K31/517 , A61K31/5377 , C07D231/56 , C07D333/56 , C07D401/04 , C07D403/04 , C07D405/04 , C07D413/12 , C07D417/04 , C07D471/04 , C07D263/54 , C07D498/04 , C07D307/81 , C07D263/57 , C12N15/09
Abstract: Provided is a bicyclic compound having an acetyl-CoA carboxylase inhibitory action. A compound represented by the formula: wherein each symbol is as described in the DESCRIPTION, or a salt thereof has an acetyl-CoA carboxylase inhibitory action, is useful for the prophylaxis or treatment of cancer, inflammatory diseases and the like, and has superior efficacy.
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公开(公告)号：US20170050974A1
公开(公告)日：2017-02-23
申请号：US14902309
申请日：2014-07-02
Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventor： Satoshi Yamamoto , Junya Shirai , Hiroyuki Watanabe , Shoji Fukumoto , Tsuneo Oda , Hidekazu Tokuhara , Yoshihide Tomata , Naoki Ishii , Michiko Tawada , Mitsunori Kono , Atsuko Ochida , Takashi Imada , Yoshiyuki Fukase , Tomoya Yukawa
IPC: C07D491/056 , C07D471/04
CPC classification number: C07D491/056 , C07D217/26 , C07D401/04 , C07D401/06 , C07D401/12 , C07D405/06 , C07D405/12 , C07D409/06 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/06 , C07D471/04 , C07D491/04 , C07D491/048 , C07F7/0812
Abstract: The present invention relates to compound (I) or a salt thereof which has a RORγt inhibitory action. wherein each symbol is as defined in the specification.
Abstract translation: 其中每个符号如说明书中所定义。
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公开(公告)号：US10252997B2
公开(公告)日：2019-04-09
申请号：US15563128
申请日：2016-03-30
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Ryo Mizojiri , Moriteru Asano , Daisuke Tomita , Hiroshi Banno , Michiko Tawada , Noriyuki Nii , Krista E. Gipson , Hironobu Maezaki , Shuntarou Tsuchiya , Mayumi Imai , Yuichiro Amano
IPC: C07D213/65 , A61K31/165 , A61K31/167 , A61K31/277 , A61K31/381 , A61K31/402 , A61K31/415 , A61K31/42 , A61K31/421 , A61K31/426 , A61K31/427 , A61K31/44 , A61K31/4412 , A61K31/4436 , A61K31/4439 , A61K31/444 , A61K31/451 , A61K31/454 , A61K31/4965 , A61K31/50 , A61K31/501 , A61K31/505 , A61K31/506 , C07D213/75 , C07D213/81 , C07D231/12 , C07D333/20 , C07D401/04 , C07D237/14 , C07D239/34 , C07D409/04 , C07D413/04 , C07D241/18 , C07D417/04 , C07C233/18 , C07C233/47 , C07D261/08 , C07D263/32 , C07D263/42 , C07D207/08 , C07D207/12 , C07D277/34 , C07D211/44 , C07D213/643 , C07D213/69 , C07C233/25 , C07C255/54 , C07D211/46 , C07D213/74 , C07D401/12 , C12N9/99 , C12N15/09
Abstract: The present invention relates to a compound which may be useful as an agent for the prophylaxis or treatment of cancer, hepatitis, hepatic fibrosis, fatty liver and the like.
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公开(公告)号：US20180319812A1
公开(公告)日：2018-11-08
申请号：US16035277
申请日：2018-07-13
Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventor： Satoshi Yamamoto , Junya Shirai , Hiroyuki Watanabe , Shoji Fukumoto , Tsuneo Oda , Hidekazu Tokuhara , Yoshihide Tomata , Naoki Ishii , Michiko Tawada , Mitsunori Kono , Atsuko Ochida , Takashi Imada , Yoshiyuki Fukase , Tomoya Yukawa
IPC: C07D491/056 , C07F7/08 , C07D217/26 , C07D413/12 , C07D401/12 , C07D405/12 , C07D401/04 , C07D413/14 , C07D491/048 , C07D471/04 , C07D417/06 , C07D413/06 , C07D409/06 , C07D405/06 , C07D401/06 , C07D491/04
CPC classification number: C07D491/056 , C07D217/26 , C07D401/04 , C07D401/06 , C07D401/12 , C07D405/06 , C07D405/12 , C07D409/06 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/06 , C07D471/04 , C07D491/04 , C07D491/048 , C07F7/0812
Abstract: The present invention relates to compound (I) or a salt thereof which has a RORγt inhibitory action. wherein each symbol is as defined in the specification.
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Patent Agency Ranking
公开(公告)号：US09365520B2
公开(公告)日：2016-06-14
申请号：US14755439
申请日：2015-06-30
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Satoshi Yamamoto , Junya Shirai , Tsuneo Oda , Mitsunori Kono , Atsuko Ochida , Takashi Imada , Hidekazu Tokuhara , Yoshihide Tomata , Naoki Ishii , Michiko Tawada , Yoshiyuki Fukase , Tomoya Yukawa , Shoji Fukumoto
IPC: C07D471/04 , C07D215/00 , C07D491/14 , C07D217/26 , C07F7/08 , C07D491/048 , C07D491/056 , A61K31/4375 , A61K31/472 , A61K31/4741 , C07D217/14
CPC classification number: C07D217/26 , A61K31/4375 , A61K31/472 , A61K31/4741 , C07D217/14 , C07D471/04 , C07D491/048 , C07D491/056 , C07D491/14 , C07F7/0812
Abstract: The present invention provides a heterocyclic compound having a RORγt inhibitory action.The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.
Abstract translation: 本发明提供具有RORγt抑制作用的杂环化合物。 本发明涉及由式（I）表示的化合物：其中每个符号如说明书中所定义。 或其盐。
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7.发明授权公开(公告)号：US10093629B2
公开(公告)日：2018-10-09
申请号：US15321609
申请日：2015-06-30
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Satoshi Yamamoto , Junya Shirai , Tsuneo Oda , Mitsunori Kono , Atsuko Ochida , Takashi Imada , Hidekazu Tokuhara , Yoshihide Tomata , Naoki Ishii , Michiko Tawada , Yoshiyuki Fukase , Tomoya Yukawa , Shoji Fukumoto
IPC: C07D217/26 , C07D491/056 , C07D491/048 , C07F7/08 , C07D471/04 , A61K31/4375 , A61K31/472 , A61K31/4741 , C07D217/14 , C07D491/14
Abstract: Provided are heterocyclic compounds having a RORγt inhibitory action represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof.
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公开(公告)号：US10053468B2
公开(公告)日：2018-08-21
申请号：US14902309
申请日：2014-07-02
Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
Inventor： Satoshi Yamamoto , Junya Shirai , Hiroyuki Watanabe , Shoji Fukumoto , Tsuneo Oda , Hidekazu Tokuhara , Yoshihide Tomata , Naoki Ishii , Michiko Tawada , Mitsunori Kono , Atsuko Ochida , Takashi Imada , Yoshiyuki Fukase , Tomoya Yukawa
IPC: C07D491/056 , C07D217/26 , C07D401/06 , C07D405/06 , C07D409/06 , C07D413/06 , C07D417/06 , C07D471/04 , C07D491/048 , C07D401/12 , C07D413/12 , C07D491/04 , C07D413/14 , C07D401/04 , C07D405/12 , C07F7/08
CPC classification number: C07D491/056 , C07D217/26 , C07D401/04 , C07D401/06 , C07D401/12 , C07D405/06 , C07D405/12 , C07D409/06 , C07D413/06 , C07D413/12 , C07D413/14 , C07D417/06 , C07D471/04 , C07D491/04 , C07D491/048 , C07F7/0812
Abstract: The present invention relates to compound (I) or a salt thereof which has a RORγt inhibitory action. wherein each symbol is as defined in the specification.
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公开(公告)号：US09650343B2
公开(公告)日：2017-05-16
申请号：US15055156
申请日：2016-02-26
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Satoshi Yamamoto , Junya Shirai , Tsuneo Oda , Mitsunori Kono , Atsuko Ochida , Takashi Imada , Hidekazu Tokuhara , Yoshihide Tomata , Naoki Ishii , Michiko Tawada , Yoshiyuki Fukase , Tomoya Yukawa , Shoji Fukumoto
IPC: C07D471/04 , C07D215/00 , C07D217/26 , C07F7/08 , C07D491/048 , C07D491/056 , A61K31/4375 , A61K31/472 , A61K31/4741 , C07D217/14 , C07D491/14
CPC classification number: C07D217/26 , A61K31/4375 , A61K31/472 , A61K31/4741 , C07D217/14 , C07D471/04 , C07D491/048 , C07D491/056 , C07D491/14 , C07F7/0812
Abstract: The present invention provides a heterocyclic compound having a RORγt inhibitory action.The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.
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公开(公告)号：US09573903B2
公开(公告)日：2017-02-21
申请号：US15055197
申请日：2016-02-26
Applicant: Takeda Pharmaceutical Company Limited
Inventor： Satoshi Yamamoto , Junya Shirai , Tsuneo Oda , Mitsunori Kono , Atsuko Ochida , Takashi Imada , Hidekazu Tokuhara , Yoshihide Tomata , Naoki Ishii , Michiko Tawada , Yoshiyuki Fukase , Tomoya Yukawa , Shoji Fukumoto
IPC: C07D471/04 , C07D215/00 , C07D217/26 , C07F7/08 , C07D491/048 , C07D491/056 , A61K31/4375 , A61K31/472 , A61K31/4741 , C07D217/14 , C07D491/14
CPC classification number: C07D217/26 , A61K31/4375 , A61K31/472 , A61K31/4741 , C07D217/14 , C07D471/04 , C07D491/048 , C07D491/056 , C07D491/14 , C07F7/0812
Abstract: The present invention provides a heterocyclic compound having a RORγt inhibitory action.The present invention relates to a compound represented by the formula (I): wherein each symbol is as defined in the specification. or a salt thereof.
Abstract translation: 本发明提供具有RORγt抑制作用的杂环化合物。 本发明涉及由式（I）表示的化合物：其中每个符号如说明书中所定义。 或其盐。
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