公开(公告)号：US20200155865A1

公开(公告)日：2020-05-21

申请号：US16615765

申请日：2018-05-22

申请人： The Regents of the University of California

发明人： Daniel C. Lu

IPC分类号： A61N2/00 ,  A61N2/02

摘要： In various embodiments methods and devices are provided for facilitating sexual function in a subject with a neuromotor disorder. In certain embodiments the methods involve providing magnetic stimulation of the spinal cord at a location, frequency and intensity sufficient to facilitate sexual function.

公开(公告)号：US20190381313A1

公开(公告)日：2019-12-19

申请号：US16479201

申请日：2018-01-24

申请人： The Regents of the University of California

发明人： Daniel C. Lu

IPC分类号： A61N1/36 ,  A61N1/05 ,  A61N2/00 ,  A61N2/02

摘要： In various embodiments, methods are provided for improving, and/or regulating, and/or restoring respiration in a subject with a respiratory deficiency. In certain embodiments the methods involve neuromodulating the cervical spinal cord of a subject by administering transcutaneous stimulation to the cervical spinal cord or a region thereof at a frequency and intensity sufficient to regulate and/or to restore respiration; and/or neuromodulating the cervical spinal cord of a subject by administering epidural stimulation to the cervical spinal cord or a region thereof at a frequency and intensity sufficient to regulate and/or to restore respiration; and/or neuromodulating the cervical spinal cord of a subject with a magnetic stimulator at a frequency and intensity sufficient to regulate and/or to restore respiration.

公开(公告)号：US20190167987A1

公开(公告)日：2019-06-06

申请号：US16200467

申请日：2018-11-26

申请人： The Regents of the University of California

发明人： Daniel C. Lu ,  V. Reggie Edgerton ,  Roland R. Roy ,  Yury P. Gerasimenko

IPC分类号： A61N1/36 ,  A61K31/517 ,  A61K31/506 ,  A61K31/4985 ,  A61K31/496 ,  A61K31/4178 ,  A61K31/527 ,  A61K31/137 ,  A61N1/05 ,  A61K31/4168

摘要： In various embodiments, methods are provided for applying transcutaneous and/or epidural spinal cord stimulation with and without selective pharmaceuticals to restore voluntary control of hand function in tetraplegic subjects.

公开(公告)号：US20170274209A1

公开(公告)日：2017-09-28

申请号：US15505053

申请日：2015-08-21

申请人： The Regents of the University of California

发明人： Victor Reggie Edgerton ,  Parag Gad ,  Roland R. Roy ,  Yury P. Gerasimenko ,  Daniel C. Lu ,  Hui Zhong

IPC分类号： A61N1/36 ,  A61K31/475 ,  A61H3/00 ,  A61K31/496 ,  A63B22/02 ,  A63B21/06

摘要： In various embodiments methods and devices are provided for regulating bladder function in a subject after a spinal cord and/or brain injury. In certain embodiments the methods comprise applying a pattern of electrical stimulation to the Lumbosacral spinal cord at a frequency and intensity sufficient to initiate micturition and/or to improve the amount of bladder emptying. In certain embodiments the electrical stimulation is at a frequency and intensity sufficient to improve the amount of bladder emptying (e.g., to provide at least 30% emptying or at least 40% emptying, or at least 50% emptying, or at least 60% emptying, or at least 70% emptying, or at least 80% emptying, or at least 90% emptying, or at least 95% emptying.

公开(公告)号：US20140296752A1

公开(公告)日：2014-10-02

申请号：US14355812

申请日：2012-11-13

申请人： The Regents of the University of California

发明人： V. Reggie Edgerton ,  Yury Gerasimenko ,  Roland R. Roy ,  Daniel C. Lu

IPC分类号： A61N1/36 ,  A61H1/00

CPC分类号： A61N1/36014 ,  A61H1/00 ,  A61H2201/10 ,  A61N1/36003 ,  A61N1/36007 ,  A61N1/36025

摘要： This disclosure provides non-invasive methods to induce motor control in a mammal subject to spinal cord or other neurological injuries. In certain embodiments the method involves administering transcutaneous electrical spinal cord stimulation (tSCS) to the mammal at a frequency and intensity that induces the desired locomotor activity.

摘要翻译： 本公开提供了在受脊髓或其他神经损伤的哺乳动物中诱导运动控制的非侵入性方法。 在某些实施方案中，该方法包括以诱导所需运动活性的频率和强度向哺乳动物施用经皮电刺激（tSCS）。