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21.发明申请Novel nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of breast cancer 有权新的核苷酸和氨基酸序列，以及其用于诊断乳腺癌的测定和方法公开(公告)号：US20070259386A1
公开(公告)日：2007-11-08
申请号：US11711827
申请日：2007-02-28
申请人： Amir Toporik , Dvir Dahary , Rotem Sorek , Sarah Pollock , Zurit Levine , Pinchas Akiva , Alexander Diber , Amit Novik , Osnat Sella-Tayor , Michal Ayalon-Soffer , Shira Walach , Shirley Sameah-Greenwald , Ronen Shemesh , Naomi Keren , Maxim Shklar
发明人： Amir Toporik , Dvir Dahary , Rotem Sorek , Sarah Pollock , Zurit Levine , Pinchas Akiva , Alexander Diber , Amit Novik , Osnat Sella-Tayor , Michal Ayalon-Soffer , Shira Walach , Shirley Sameah-Greenwald , Ronen Shemesh , Naomi Keren , Maxim Shklar
CPC分类号： G01N33/57415 , C07K14/47 , C12Q1/6886 , C12Q2600/112 , C12Q2600/158
摘要： Novel markers for breast cancer that are both sensitive and accurate. These markers are overexpressed in breast cancer specifically, as opposed to normal breast tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of breast cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between breast cancer and non-cancerous states.
摘要翻译： 乳腺癌的新型标记物既敏感又准确。 这些标志物在乳腺癌中特异性地过表达，与正常的乳腺组织相反。 这些标记物在患者样本中单独或组合的测量提供了诊断者可以与乳腺癌的可能诊断相关的信息。 本发明的标记物单独或组合显示乳腺癌与非癌状态之间的高度差异检测。
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22.发明申请Novel nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of lung cancer 失效新型核苷酸和氨基酸序列，以及其用于诊断肺癌的测定和方法公开(公告)号：US20060046257A1
公开(公告)日：2006-03-02
申请号：US11051720
申请日：2005-01-27
申请人： Sarah Pollock , Zurit Levine , Amit Novik , Dvir Dahary , Rotem Sorek , Amir Toporik , Shirley Sameah-Greenwald , Osnat Sella-Tavor , Alexander Diber , Gad Cojocaru , Michal Ayalon-Soffer , Shira Walach , Pinchas Akiva , Naomi Keren , Ronen Shemesh
发明人： Sarah Pollock , Zurit Levine , Amit Novik , Dvir Dahary , Rotem Sorek , Amir Toporik , Shirley Sameah-Greenwald , Osnat Sella-Tavor , Alexander Diber , Gad Cojocaru , Michal Ayalon-Soffer , Shira Walach , Pinchas Akiva , Naomi Keren , Ronen Shemesh
IPC分类号： C12Q1/68
CPC分类号： G01N33/57423 , C12Q1/6886 , C12Q2600/112
摘要： Novel markers for lung cancer that are both sensitive and accurate. These markers are overexpressed in lung cancer specifically, as opposed to normal lung tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of lung cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between lung cancer and non-cancerous states.
摘要翻译： 肺癌的新型标志物既敏感又准确。 与正常肺组织相反，这些标志物特异性地在肺癌中过度表达。 这些标记物在患者样本中单独或组合的测量提供了诊断者可以与肺癌可能诊断相关的信息。 本发明的标记物单独或组合显示出肺癌和非癌状态之间的高度差异检测。
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23.发明申请Novel Nucleotide and Amino Acid Sequences, and Assays and Methods of Use Thereof for Diagnosis of Lung Cancer 审中-公开新型核苷酸和氨基酸序列及其用于肺癌诊断的方法及方法公开(公告)号：US20100068736A1
公开(公告)日：2010-03-18
申请号：US12557253
申请日：2009-09-10
申请人： Sarah Pollock , Zurit Levine , Amit Novik , Dvir Dahary , Rotem Sorek , Amir Toporik , Shirley Sameah-Greenwald , Osnat Sella-Tavor , Alexander Diber , Gad S. Cojocaru , Michal Ayalon-Soffer , Shira Walach , Pinchas Akiva , Naomi Keren , Ronen Shemesh
发明人： Sarah Pollock , Zurit Levine , Amit Novik , Dvir Dahary , Rotem Sorek , Amir Toporik , Shirley Sameah-Greenwald , Osnat Sella-Tavor , Alexander Diber , Gad S. Cojocaru , Michal Ayalon-Soffer , Shira Walach , Pinchas Akiva , Naomi Keren , Ronen Shemesh
IPC分类号： G01N33/53 , C07K2/00 , C07K16/00 , G01N33/574
CPC分类号： G01N33/57423 , C12Q1/6886 , C12Q2600/112 , C12Q2600/158
摘要： Novel markers for lung cancer that are both sensitive and accurate. These markers are overexpressed in lung cancer specifically, as opposed to normal lung tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of lung cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between lung cancer and non-cancerous states.
摘要翻译： 肺癌的新型标志物既敏感又准确。 与正常肺组织相反，这些标志物特异性地在肺癌中过度表达。 这些标记物在患者样本中单独或组合的测量提供了诊断者可以与肺癌可能诊断相关的信息。 本发明的标记物单独或组合显示出肺癌和非癌状态之间的高度差异检测。
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24.发明授权Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of lung cancer 失效核苷酸和氨基酸序列，以及其用于诊断肺癌的测定和方法公开(公告)号：US07667001B1
公开(公告)日：2010-02-23
申请号：US11978554
申请日：2007-10-30
申请人： Sarah Pollock , Zurit Levine , Amit Novik , Dvir Dahary , Rotem Sorek , Amir Toporik , Shirley Sameah-Greenwald , Osnat Sella-Tavor , Alexander Diber , Gad S. Cojocaru , Michal Avalon-Soffer , Shira Walach , Pinchas Akiva , Naomi Keren , Ronen Shemesh
发明人： Sarah Pollock , Zurit Levine , Amit Novik , Dvir Dahary , Rotem Sorek , Amir Toporik , Shirley Sameah-Greenwald , Osnat Sella-Tavor , Alexander Diber , Gad S. Cojocaru , Michal Avalon-Soffer , Shira Walach , Pinchas Akiva , Naomi Keren , Ronen Shemesh
IPC分类号： C07K16/00
CPC分类号： G01N33/57423 , C12Q1/6886 , C12Q2600/112 , C12Q2600/158
摘要： Novel markers for lung cancer that are both sensitive and accurate. These markers are overexpressed in lung cancer specifically, as opposed to normal lung tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of lung cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between lung cancer and non-cancerous states.
摘要翻译： 肺癌的新型标志物既敏感又准确。 与正常肺组织相反，这些标志物特异性地在肺癌中过度表达。 这些标记物在患者样本中单独或组合的测量提供了诊断者可以与肺癌可能诊断相关的信息。 本发明的标记物单独或组合显示出肺癌和非癌状态之间的高度差异检测。
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25.发明授权Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of lung cancer 失效核苷酸和氨基酸序列，以及其用于诊断肺癌的测定和方法公开(公告)号：US07569662B2
公开(公告)日：2009-08-04
申请号：US11051720
申请日：2005-01-27
申请人： Sarah Pollock , Zurit Levine , Amit Novik , Dvir Dahary , Rotem Sorek , Amir Toporik , Shirley Sameah-Greenwald , Osnat Sella-Tavor , Alexander Diber , Gad S. Cojocaru , Michal Ayalon-Soffer , Shira Walach , Pinchas Akiva , Naomi Keren , Ronen Shemesh
发明人： Sarah Pollock , Zurit Levine , Amit Novik , Dvir Dahary , Rotem Sorek , Amir Toporik , Shirley Sameah-Greenwald , Osnat Sella-Tavor , Alexander Diber , Gad S. Cojocaru , Michal Ayalon-Soffer , Shira Walach , Pinchas Akiva , Naomi Keren , Ronen Shemesh
IPC分类号： A61K38/00
CPC分类号： G01N33/57423 , C12Q1/6886 , C12Q2600/112
摘要： Novel markers for lung cancer that are both sensitive and accurate. These markers are overexpressed in lung cancer specifically, as opposed to normal lung tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of lung cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between lung cancer and non-cancerous states.
摘要翻译： 肺癌的新型标志物既敏感又准确。 与正常肺组织相反，这些标志物特异性地在肺癌中过度表达。 这些标记物在患者样本中单独或组合的测量提供了诊断者可以与肺癌可能诊断相关的信息。 本发明的标记物单独或组合显示出肺癌和非癌状态之间的高度差异检测。
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26.发明授权Nucleotide and amino acid sequences, and assays and methods of use thereof for diagnosis of breast cancer 有权核苷酸和氨基酸序列，以及其用于诊断乳腺癌的测定和方法公开(公告)号：US07528243B2
公开(公告)日：2009-05-05
申请号：US11711827
申请日：2007-02-28
申请人： Amir Toporik , Dvir Dahary , Rotem Sorek , Sarah Pollock , Zurit Levine , Pinchas Akiva , Alexander Diber , Amit Novik , Osnat Sella-Tavor , Michal Ayalon-Soffer , Shira Walach , Shirley Sameah-Greenwald , Ronen Shemesh , Naomi Keren , Maxim Shklar
发明人： Amir Toporik , Dvir Dahary , Rotem Sorek , Sarah Pollock , Zurit Levine , Pinchas Akiva , Alexander Diber , Amit Novik , Osnat Sella-Tavor , Michal Ayalon-Soffer , Shira Walach , Shirley Sameah-Greenwald , Ronen Shemesh , Naomi Keren , Maxim Shklar
CPC分类号： G01N33/57415 , C07K14/47 , C12Q1/6886 , C12Q2600/112 , C12Q2600/158
摘要： Novel markers for breast cancer that are both sensitive and accurate. These markers are overexpressed in breast cancer specifically, as opposed to normal breast tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of breast cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between breast cancer and non-cancerous states.
摘要翻译： 乳腺癌的新型标记物既敏感又准确。 这些标志物在乳腺癌中特异性地过表达，与正常的乳腺组织相反。 这些标记物在患者样本中单独或组合的测量提供了诊断者可以与乳腺癌的可能诊断相关的信息。 本发明的标记物单独或组合显示乳腺癌与非癌状态之间的高度差异检测。
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公开(公告)号：US20060068405A1
公开(公告)日：2006-03-30
申请号：US11043860
申请日：2005-01-27
申请人： Alex Diber , Sarah Pollock , Zurit Levine , Sergey Nemzer , Vladimir Grebinskiy , Brian Meloon , Andrew Olson , Avi Rosenberg , Ami Haviv , Shaul Zevin , Tomer Zekharia , Zipi Shaked , Moshe Olshansky , Ariel Farkash , Eyal Privman , Amit Novik , Naomi Keren , Gad Cojocaru , Pinchas Akiva , Yossi Cohen , Ronen Shemesh , Osnat Sella-Tavor , Liat Mintz , Hanqing Xie , Dvir Dahary , Erez Levanon , Shiri Freilich , Nili Beck , Wei-Yong Zhu , Alon Wasserman , Chen Chermesh , Idit Azar , Rotem Sorek , Jeanne Bernstein
发明人： Alex Diber , Sarah Pollock , Zurit Levine , Sergey Nemzer , Vladimir Grebinskiy , Brian Meloon , Andrew Olson , Avi Rosenberg , Ami Haviv , Shaul Zevin , Tomer Zekharia , Zipi Shaked , Moshe Olshansky , Ariel Farkash , Eyal Privman , Amit Novik , Naomi Keren , Gad Cojocaru , Pinchas Akiva , Yossi Cohen , Ronen Shemesh , Osnat Sella-Tavor , Liat Mintz , Hanqing Xie , Dvir Dahary , Erez Levanon , Shiri Freilich , Nili Beck , Wei-Yong Zhu , Alon Wasserman , Chen Chermesh , Idit Azar , Rotem Sorek , Jeanne Bernstein
CPC分类号： C07K14/705 , G16B25/00 , G16B30/00 , G16B50/00
摘要： Polypeptide sequences and polynucleotide sequences are provided. Also provided are annotative information concerning such sequences and uses for these sequences.
摘要翻译： 提供多肽序列和多核苷酸序列。 还提供了关于这些序列的这些序列和用途的注释信息。
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公开(公告)号：US20110091454A1
公开(公告)日：2011-04-21
申请号：US12701651
申请日：2010-02-08
申请人： Alex Diber , Sarah Pollock , Zurit Levine , Sergey Nemzer , Vladimir Grebinskiy , Brian Meloon , Andrew Olson , Avi Rosenberg , Ami Haviv , Shaul Zevin , Tomer Zekharia , Zipi Shaked , Moshe Olshansky , Ariel Farkash , Eyal Privman , Amit Novik , Naomi Keren , Gad S. Cojocaru , Pinchas Akiva , Yossi Cohen , Ronen Shemesh , Osnat Sella-Tavor , Liat Mintz , Hanqing Xie , Dvir Dahary , Erez Levanon , Shiri Freilich , Nili Beck , Wei-Yong Zhu , Alon Wasserman , Chen Chermesh , Idit Azar , Rotem Sorek , Jeanne Bernstein
发明人： Alex Diber , Sarah Pollock , Zurit Levine , Sergey Nemzer , Vladimir Grebinskiy , Brian Meloon , Andrew Olson , Avi Rosenberg , Ami Haviv , Shaul Zevin , Tomer Zekharia , Zipi Shaked , Moshe Olshansky , Ariel Farkash , Eyal Privman , Amit Novik , Naomi Keren , Gad S. Cojocaru , Pinchas Akiva , Yossi Cohen , Ronen Shemesh , Osnat Sella-Tavor , Liat Mintz , Hanqing Xie , Dvir Dahary , Erez Levanon , Shiri Freilich , Nili Beck , Wei-Yong Zhu , Alon Wasserman , Chen Chermesh , Idit Azar , Rotem Sorek , Jeanne Bernstein
IPC分类号： A61K39/395 , C07K16/00 , G01N33/53 , A61P35/00
CPC分类号： C07K14/705 , G16B25/00 , G16B30/00 , G16B50/00
摘要： Polypeptide sequences and polynucleotide sequences are provided. Also provided are annotative information concerning such sequences and uses for these sequences.
摘要翻译： 提供多肽序列和多核苷酸序列。 还提供了关于这些序列的这些序列和用途的注释信息。
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公开(公告)号：US20060147946A1
公开(公告)日：2006-07-06
申请号：US11051725
申请日：2005-01-27
申请人： Pinchas Akiva , Alexander Dlber , Sarah Pollock , Zurit Levine , Sergey Nemzer , Vladimir Grebinskiy , Brian Meloon , Andrew Olson , Avi Rosenberg , Ami Haviv , Shaul Zevin , Tomer Zekhari , Zipi Shaged , Moshe Olshansky , Arial Farkash , Eyal Privman , Amit Novik , Naomi Keren , Gad Cojocaru , Yossi Cohen , Ronen Shemesh , Osnat Sella-Tavor , Liat Mintz , Hanquing Xie , Dvir Dahary , Erez Levanon , Shiri Freilich , Nili Beck , Wei-Yong Zhu , Alon Wasserman , Chen Chermesh , Idit Azar , Rotem Sorek , Jeanne Bernstein
发明人： Pinchas Akiva , Alexander Dlber , Sarah Pollock , Zurit Levine , Sergey Nemzer , Vladimir Grebinskiy , Brian Meloon , Andrew Olson , Avi Rosenberg , Ami Haviv , Shaul Zevin , Tomer Zekhari , Zipi Shaged , Moshe Olshansky , Arial Farkash , Eyal Privman , Amit Novik , Naomi Keren , Gad Cojocaru , Yossi Cohen , Ronen Shemesh , Osnat Sella-Tavor , Liat Mintz , Hanquing Xie , Dvir Dahary , Erez Levanon , Shiri Freilich , Nili Beck , Wei-Yong Zhu , Alon Wasserman , Chen Chermesh , Idit Azar , Rotem Sorek , Jeanne Bernstein
IPC分类号： C12Q1/68 , C07H21/04 , C12P21/06 , C07K14/705
CPC分类号： C07K14/705 , G16B25/00 , G16B30/00 , G16B50/00
摘要： Novel alpha 1 subunit splice variants, including nucleic and amino acid sequences. Methods of use thereof are also described.
摘要翻译： 新的α1亚基剪接变体，包括核酸和氨基酸序列。 还描述了其使用方法。
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30.发明申请公开(公告)号：US20090075257A1
公开(公告)日：2009-03-19
申请号：US11831404
申请日：2007-07-31
申请人： Sarah Pollock , Osnat Sella-Tavor , Amit Novik , Elena Tsypkin , Dan Sztybel , Shira Walach
发明人： Sarah Pollock , Osnat Sella-Tavor , Amit Novik , Elena Tsypkin , Dan Sztybel , Shira Walach
CPC分类号： C12Q1/6886 , C12Q2600/156 , C12Q2600/158 , G16B25/00 , G16B40/00
摘要： Novel splice variant nucleic acid and amino acid sequences are provided. The novel splice variants and their nucleic acid sequences may be used for diagnosis of variant-detectable diseases particularly cancerous diseases.
摘要翻译： 提供了新的剪接变体核酸和氨基酸序列。 新颖的剪接变体及其核酸序列可用于诊断可变型可检测疾病，特别是癌性疾病。
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