公开(公告)号：US20110040233A1

公开(公告)日：2011-02-17

申请号：US12913054

申请日：2010-10-27

申请人： Salim Kassem

发明人： Salim Kassem

IPC分类号： A61M27/00

CPC分类号： A61M27/006 ,  A61M27/008 ,  A61M2205/3344 ,  A61M2205/3523

摘要： Devices and methods useful for non-invasively indicating the position or setting of a mechanical device, such as a sensor or control in an implanted medical device, are disclosed. In one exemplary embodiment, a valve housing adapted to receive fluid flow therethrough is provided. The flow of fluid through the valve housing can be controlled, for example, by a valve assembly that has a plurality of predetermined pressure settings. A radio frequency tag can be disposed in the valve assembly, and the masking element and the radio frequency tag can be configured to move relative to one another. The relative positions of the masking element and the radio frequency tag can alter the response of the radio frequency tag to a wireless signal (which can be emitted from an external reading device, for example) and thereby indicate the pressure setting of the valve assembly. For example, in some embodiments, the masking element can selectively cover at least part of the radio frequency tag according to the pressure setting of the valve assembly, which can change a characteristic of the radio frequency tag's response to the wireless signal.

摘要翻译： 公开了用于非侵入式地指示机械装置（例如植入医疗装置中的传感器或控制器）的位置或设置的装置和方法。 在一个示例性实施例中，提供了适于接收流过其中的流体流动的阀壳体。 通过阀壳体的流体流可以例如通过具有多个预定压力设置的阀组件来控制。 射频标签可以设置在阀组件中，并且掩模元件和射频标签可被配置为相对于彼此移动。 掩蔽元件和射频标签的相对位置可以改变射频标签对无线信号（例如可以从外部读取装置发射）的响应，从而指示阀组件的压力设置。 例如，在一些实施例中，屏蔽元件可以根据阀组件的压力设置选择性地覆盖射频标签的至少一部分，这可以改变射频标签对无线信号的响应的特性。

公开(公告)号：US07889069B2

公开(公告)日：2011-02-15

申请号：US11097499

申请日：2005-04-01

申请人： Douglas A. Fifolt ,  Miki Rosenberg

发明人： Douglas A. Fifolt ,  Miki Rosenberg

IPC分类号： G08B1/08

CPC分类号： A61B5/0002 ,  A61B5/0031 ,  A61B5/7232

摘要： A device and method for monitoring a patient having a sensing device taking sensor data continuously and a transmitter located on the patient and internally powered. The transmitter is normally in a power-down state and powered-up for transmitting the sensor data. A receiver is located remote from the patient and receives the sensor data transmitted wirelessly from the transmitter. The transmission is typically a burst and can also be initiated on a command. For the burst, the sensor data is accumulated over a first period. The transmitter can transmit the sensor data over a second period of time. The second period of time is shorter than the first period of time. Once the transmission is complete, transmitter can be powered down. A further step displays the sensor data at the receiver in pseudo real-time. The display is shifted by a sum of the first and the second period of time.

摘要翻译： 一种用于监测患者的装置和方法，所述患者具有连续获取传感器数据的感测装置和位于患者身上且内部供电的发射器。 发射机通常处于掉电状态，并通电以传输传感器数据。 接收器位于远离病人的位置，并接收从发射机无线传输的传感器数据。 传输通常是突发，也可以在命令上启动。 对于突发，传感器数据在第一周期内累积。 发射机可以在第二个时间段内传输传感器数据。 第二个时间段比第一个时间段短。 一旦传输完成，发射机可以掉电。 进一步的步骤在伪实时地显示接收机处的传感器数据。 显示器移动了第一和第二时间段的总和。

公开(公告)号：US07883526B2

公开(公告)日：2011-02-08

申请号：US11678351

申请日：2007-02-23

申请人： Donald K. Jones ,  Vladimir Mitelberg ,  William W. Sowers

发明人： Donald K. Jones ,  Vladimir Mitelberg ,  William W. Sowers

IPC分类号： A61M29/00

CPC分类号： A61B17/12022 ,  A61B17/12109 ,  A61B17/12113 ,  A61B17/1214 ,  A61B17/12154

摘要： A coil device is provided with a stretch resistant feature. The device includes a wound coil defining a lumen and a stretch resistant member at least partially received within the lumen. A headpiece is formed by a joining of the coil and a restrictor member, typically by plasma welding. The restrictor member is also at least partially received within the lumen and defines an aperture adapted to movably receive a portion of the stretch resistant member to allow the wound coil to stretch and elongate. The stretch resistant member includes an enlarged portion that is larger than the aperture and adapted to engage the restrictor member to prevent or resist stretching of the wound coil. The restrictor member may be provided as a separate element fixedly secured to the coil wire, or the coil wire may include one or more minor turns adapted to perform the function of the restrictor member.

摘要翻译： 线圈装置具有抗拉特性。 该装置包括限定内腔的缠绕线圈和至少部分地容纳在内腔内的抗拉构件。 通常通过等离子体焊接，线圈和节流部件的接合形成头盔。 限流器构件还至少部分地容纳在内腔内并且限定适于可移动地容纳抗拉构件的一部分以允许缠绕线圈拉伸和伸长的孔。 抗拉构件包括比孔大的扩大部分，并且适于接合限制器构件以防止或阻止缠绕线圈的拉伸。 限流器构件可以被设置为固定地固定到线圈线的单独元件，或者线圈线可以包括适于执行限制器构件的功能的一个或多个小匝。

公开(公告)号：US07875044B2

公开(公告)日：2011-01-25

申请号：US11663489

申请日：2005-10-14

申请人： Frederick Feller, III ,  Donald K. Jones ,  Darren R. Sherman

发明人： Frederick Feller, III ,  Donald K. Jones ,  Darren R. Sherman

IPC分类号： A61B17/08

CPC分类号： A61B17/12022 ,  A61B17/12118 ,  A61B17/12172 ,  A61B2017/12054 ,  A61F2002/823

摘要： A method of occluding a defect in the wall of a body vessel is provided. An outlet portion of a microcatheter is delivered to the defect, then at least a body portion of a thin film occlusion device is radially expanded from a collapsed orientation to a deployed orientation for engaging the microcatheter and covering at least a portion of the defect. Thereafter, an embolic media is released into the defect from the microcatheter for facilitating thrombosis. The body portion of the occlusion device is substantially porous in the collapsed orientation, but substantially non-porous in the deployed orientation for preventing prolapse of the embolic media into the body vessel.

摘要翻译： 提供了一种在身体容器的壁中闭塞缺陷的方法。 微导管的出口部分被输送到缺陷，然后薄膜闭塞装置的至少主体部分从收缩方向径向扩张到展开方向，以便与微导管接合并覆盖缺陷的至少一部分。 此后，栓塞介质从微导管释放到缺陷中以便于血栓形成。 闭塞装置的主体部分在塌缩方向上基本上是多孔的，但是在展开方向上基本上是无孔的，以防止栓塞介质向身体容器脱垂。

公开(公告)号：US20100286585A1

公开(公告)日：2010-11-11

申请号：US12696588

申请日：2010-01-29

申请人： Thomas M. DiMauro ,  Alan Dextradeur ,  Sean Lilienfeld ,  Ramakrishna Venugopalan

发明人： Thomas M. DiMauro ,  Alan Dextradeur ,  Sean Lilienfeld ,  Ramakrishna Venugopalan

IPC分类号： A61M5/00

CPC分类号： A61K36/9066 ,  A61K31/12 ,  C07D279/28

摘要： A method for reducing or preventing a human brain disorder relating to the presence of a pathogenic substance in cerebrospinal fluid by selecting a human for treatment as a patient and placing a proximal end of a first catheter, having at least a first lumen, in a first sub-dural location within the brain of the patient to establish open communication between the first lumen and cerebrospinal fluid of the patient. For an extended period of time, a curcumin agent selected from at least one of curcumin, a curcumin hybrid and a curcumin analog is delivered to the cerebrospinal fluid to interact with the pathogenic substance to attenuate its effect on the brain.

摘要翻译： 一种减少或预防与脑脊髓液中存在病原物质有关的人脑疾病的方法，该方法是通过选择人作为患者进行治疗，并将具有至少第一管腔的第一导管的近端放置在第一 在患者的脑内部的硬脑膜下位置以建立患者的第一腔和脑脊液之间的开放的连通。 在长时间内，选自姜黄素，姜黄素混合物和姜黄素类似物中的至少一种的姜黄素被递送到脑脊液中以与致病物质相互作用以减弱其对脑的作用。

公开(公告)号：US07819907B2

公开(公告)日：2010-10-26

申请号：US11552165

申请日：2006-10-24

申请人： Victor B. Agbodoe

发明人： Victor B. Agbodoe

IPC分类号： A61B17/84

CPC分类号： A61B17/688 ,  A61B17/8625 ,  A61K9/0043

摘要： A method and device for reattaching adjacent bone plates includes an inner seat, a pin, and an outer seat. The pin is fixedly connected to the inner seat. The outer seat is selectively connected to the pin so that adjacent bone plates are securely held in place between the inner seat and the outer seat. The outer seat includes a first outer seat and a second outer seat that are slidably connected together. The first outer seat has a slot. The second outer seat also has a slot. The first outer seat and the second outer seat are movable between a pin engaging position and a pin locking position.

摘要翻译： 用于重新附接相邻骨板的方法和装置包括内座椅，销和外座椅。 销固定地连接到内座。 外座椅选择性地连接到销，使得相邻的骨板被牢固地保持在内座椅和外座椅之间的适当位置。 外座椅包括可滑动地连接在一起的第一外座椅和第二外座椅。 第一个外座椅有一个插槽。 第二个外座椅也有一个插槽。 第一外座椅和第二外座椅可在销接合位置和销锁定位置之间移动。

公开(公告)号：US07819891B2

公开(公告)日：2010-10-26

申请号：US11395924

申请日：2006-03-31

申请人： Keith Balgobin ,  Donald K. Jones ,  Vladimir Mitelberg ,  John H. Thinnes, Jr.

发明人： Keith Balgobin ,  Donald K. Jones ,  Vladimir Mitelberg ,  John H. Thinnes, Jr.

IPC分类号： A61M29/00 ,  A61F2/06

CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/12154 ,  A61B2017/00477 ,  A61B2017/00862 ,  A61B2017/12054

摘要： A medical device for placing an embolic device at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member slidably disposed within the lumen of the catheter. An embolic device is retained within the delivery catheter by a mechanical interlocking mechanism which includes an engagement member attached to the distal end of the pusher member and extends through a retaining ring at the proximal end of the embolic device. A detachment member extends through an aperture at the distal end of the engagement member thereby locking the embolic device onto the pusher member. A kicker member extends from the distal end of the pusher member and is biased so as to lift the retaining ring off of the engagement member to ensure the release of the embolic device when the detachment member is withdrawn from the aperture of the engagement member.

摘要翻译： 一种用于将栓塞装置放置在主体容器内的预定位置处的医疗装置，包括输送导管和可滑动地设置在导管内腔内的柔性推动器构件。 栓塞装置通过机械互锁机构保持在输送导管内，该机械互锁机构包括附接到推动器构件的远端的接合构件并延伸穿过栓塞装置的近端处的保持环。 分离构件延伸穿过接合构件的远端处的孔，从而将栓塞装置锁定到推动器构件上。 推动器构件从推动器构件的远端延伸并且被偏压以便将保持环从接合构件提起，以确保当分离构件从接合构件的孔中取出时栓塞装置的释放。

公开(公告)号：US07819889B2

公开(公告)日：2010-10-26

申请号：US10251162

申请日：2002-09-20

申请人： Stephen R. Healy ,  Amanda Jordan

发明人： Stephen R. Healy ,  Amanda Jordan

IPC分类号： A61M29/00

CPC分类号： A61B17/1214 ,  A61B17/12022 ,  A61B2017/1205

摘要： A detachable introducer and method of using such introducer is disclosed for inserting an embolic coil deployment system into the tortuous vasculature of the human brain for placing an embolic coil within an aneurysm. The introducer includes a sheath having a lumen, a side opening and a longitudinal slit. A deployment catheter with a conical expander member is slideably disposed through the side opening of the sheath and through the lumen of the sheath. The conical expander member detaches the introducer from the deployment catheter through the longitudinal slit of the sheath.

摘要翻译： 公开了一种可拆卸的导引器和使用这种导引器的方法，用于将栓塞线圈展开系统插入人脑的弯曲脉管系统中，以将栓塞线圈放置在动脉瘤内。 引导器包括具有内腔，侧开口和纵向狭缝的护套。 具有锥形膨胀器构件的展开导管可滑动地设置穿过护套的侧开口并穿过护套的内腔。 锥形膨胀器构件通过护套的纵向狭缝将导引器从展开导管分离。

公开(公告)号：US07799052B2

公开(公告)日：2010-09-21

申请号：US11471801

申请日：2006-06-21

申请人： Keith Balgobin ,  Vladimir Mitelberg ,  Dirk Tenne ,  John H. Thinnes, Jr.

发明人： Keith Balgobin ,  Vladimir Mitelberg ,  Dirk Tenne ,  John H. Thinnes, Jr.

IPC分类号： A61M29/00 ,  A61F2/06

CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/12154 ,  A61B2017/00477 ,  A61B2017/12054

摘要： A medical device for placing an embolic device at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member slidably disposed within the lumen of the catheter. An embolic device is retained within the delivery catheter by a mechanical interlocking mechanism which includes an engagement member attached to the distal end of the pusher member and extends through a retaining ring at the proximal end of the embolic device. A detachment member extends through an aperture at the distal end of the engagement member thereby locking the embolic device onto the pusher member. A kicker tongue which is formed as an extension of a portion of the wall of the pusher member extends distally from the distal end of the pusher member and is biased so as to lift the retaining ring off of the engagement member to ensure the release of the embolic device when the detachment member is withdrawn from the aperture of the engagement member.

摘要翻译： 一种用于将栓塞装置放置在主体容器内的预定位置处的医疗装置，包括输送导管和可滑动地设置在导管内腔内的柔性推动器构件。 栓塞装置通过机械互锁机构保持在输送导管内，该机械互锁机构包括附接到推动器构件的远端的接合构件并延伸穿过栓塞装置的近端处的保持环。 分离构件延伸穿过接合构件的远端处的孔，从而将栓塞装置锁定到推动器构件上。 形成为推动器构件的壁的一部分的延伸部的推杆舌片从推动器构件的远端向远侧延伸并且被偏压以将保持环从接合构件提升以确保释放 当分离构件从接合构件的孔中取出时，栓塞装置。

公开(公告)号：US07780645B2

公开(公告)日：2010-08-24

申请号：US11663675

申请日：2005-10-26

申请人： Donald K. Jones

发明人： Donald K. Jones

IPC分类号： A61M31/00 ,  A61K9/50

CPC分类号： A61B17/12022 ,  A61B17/12113 ,  A61B17/12118 ,  A61B17/12186 ,  A61B17/1219 ,  A61B2017/00539 ,  A61B2017/00898 ,  A61B2017/1205

摘要： A method of delivering embolic particles to an aneurysm includes inserting a delivery catheter into the vasculature of a patient and directing the distal end of the delivery catheter to a pre-selected deployment site. Embolic particles are loaded into the delivery catheter, and hydraulic pressure is applied to move the embolic particles through the delivery catheter. The hydraulic pressure is adjusted to control the velocity of the embolic particles and to reduce jetting.

摘要翻译： 将栓塞颗粒递送到动脉瘤的方法包括将输送导管插入患者的脉管系统并将输送导管的远端引导到预先选择的部署位置。 栓塞颗粒被装载到输送导管中，并施加液压以通过输送导管移动栓塞颗粒。 调节液压以控制栓塞颗粒的速度并减少喷射。