公开(公告)号：US20140031802A1

公开(公告)日：2014-01-30

申请号：US13952013

申请日：2013-07-26

申请人： CardioFocus, Inc.

发明人： Gerald Melsky ,  Jeffrey M. Arnold ,  Edward L. Sinofsky ,  Norman E. Farr

IPC分类号： A61B18/22

CPC分类号： A61B18/1492 ,  A61B1/00045 ,  A61B1/00135 ,  A61B1/00165 ,  A61B1/00195 ,  A61B1/05 ,  A61B1/3137 ,  A61B18/1482 ,  A61B18/1815 ,  A61B18/22 ,  A61B18/24 ,  A61B2018/0022 ,  A61B2018/00351 ,  A61B2018/00375 ,  A61B2018/00577 ,  A61B2018/00982 ,  A61B2018/0212 ,  A61B2018/0262 ,  A61B2018/2261 ,  A61B2090/065 ,  A61B2090/3966 ,  A61N7/022 ,  A61N2005/1003

摘要： Guided ablation instruments are disclosed for creating lesions in tissue, especially cardiac tissue for treatment of arrhythmias, including atrial fibrillation. In one aspect of the invention, a percutaneous catheter is disclosed with an endoscope positionable in the instrument's distal end region to obtain an image. The image allows the clinician to determine whether contact has been achieved (or blood has been cleared from an ablative energy transmission path) before ablation begins or while ablation is occurring. In one embodiment, percutaneous ablation catheters are disclosed having at least one central lumen and one or more balloon structures at the distal end region of the instrument. Also disposed in the distal end region are an illuminating light source and an endoscope capable of collecting sufficient light to relay an image to the user. The instruments can further include an ablation element.

摘要翻译： 公开了引导消融器械用于在组织中产生损伤，特别是用于治疗心律失常的心脏组织，包括房颤。 在本发明的一个方面，公开了一种经皮导管，其具有可置于仪器的远端区域中的内窥镜，以获得图像。 图像允许临床医生确定在消融开始之前还是在消融期间已经实现了接触（或者从消融能量传递路径中清除血液）。 在一个实施例中，公开了经皮消融导管，其在器械的远端区域具有至少一个中心腔和一个或多个气囊结构。 还设置在远端区域中的是能够收集足够的光以将图像中继给用户的照明光源和内窥镜。 仪器还可以包括消融元件。

公开(公告)号：US20130289358A1

公开(公告)日：2013-10-31

申请号：US13849898

申请日：2013-03-25

申请人： CARDIOFOCUS, INC.

发明人： Gerald Melsky ,  Stephen Sagon

IPC分类号： A61B18/14

CPC分类号： A61B18/1492 ,  A61B18/24 ,  A61B2017/00057 ,  A61B2017/00123 ,  A61B2017/0046 ,  A61B2018/00196 ,  A61B2018/00982 ,  A61B2018/1861 ,  A61B2018/2025 ,  A61B2018/2261 ,  A61B2018/2272 ,  A61B2090/306 ,  A61N7/022

摘要： A cardiac tissue ablation system according to one embodiment includes an elongate catheter configured to deliver a distal end thereof to a patient's heart and an expandable member formed at the distal portion of the catheter. The expandable member has an elastic portion configured to conform to the shape of a target tissue region upon expansion. The system further includes an energy emitter movably disposed within a lumen of the catheter. The energy emitter is configured to deliver radiant ablative energy to the target tissue region. The system further includes a controller that includes a safety shut-off feature for automatically shutting off power to the energy emitter when a prescribed event occurs resulting in power to the energy emitter being stopped.

摘要翻译： 根据一个实施例的心脏组织消融系统包括被配置为将其远端传送到患者心脏的细长导管和形成在导管的远端部分处的可扩张构件。 可膨胀构件具有弹性部分，其构造成在膨胀时符合目标组织区域的形状。 该系统还包括可移动地设置在导管的内腔内的能量发射器。 能量发射器被配置为向目标组织区域传递辐射消融能量。 该系统还包括控制器，该控制器包括安全切断功能，用于在规定的事件发生时自动关闭对能量发射器的电力，导致能量发射器停止的电力。

公开(公告)号：US20040147911A1

公开(公告)日：2004-07-29

申请号：US10756645

申请日：2004-01-13

申请人： CARDIOFOCUS, INC.

发明人： Edward L. Sinofsky

IPC分类号： A61B018/24

CPC分类号： A61B18/22 ,  A61B18/1492 ,  A61B18/24 ,  A61B2017/00057 ,  A61B2017/00243 ,  A61B2017/22058 ,  A61B2017/22059 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00839 ,  A61B2018/2238 ,  A61B2018/2261 ,  A61B2018/2272 ,  A61B2018/2288 ,  A61M25/0105 ,  A61N7/02

摘要： Surgical ablation instruments are disclosed for creating circumferential lesions in tissue, including cardiac tissue for treatment of arrhythmias and other diseases. These photoablative instruments include an elongate housing and an ablation element disposed within a lumen of the housing. A connecting element associated with the elongate housing brings together the proximal and distal ends of the elongate housing to form a loop, thereby creating an encircling lesion to be formed with the ablation energy.

摘要翻译： 公开了用于在组织中产生周围损伤的手术消融器械，包括用于治疗心律失常和其它疾病的心脏组织。 这些光刻仪器包括细长壳体和设置在壳体的内腔内的消融元件。 与细长壳体相关联的连接元件将细长壳体的近端和远端组合在一起形成环，由此产生将被消融能量形成的环绕病变。

公开(公告)号：US20220296297A1

公开(公告)日：2022-09-22

申请号：US17837734

申请日：2022-06-10

申请人： CardioFocus, Inc.

发明人： Gerald Melsky ,  Brian Estabrook ,  Lincoln Baxter ,  Sergei Babko-Malyi ,  Ronald Green ,  Paul DiCesare

IPC分类号： A61B18/18 ,  A61B18/24 ,  A61B17/32

摘要： An ablation instrument (e.g., an ablation balloon catheter system) includes an elongate catheter having a housing with a window formed therein. An energy emitter is coupled to the elongate catheter and is configured to deliver ablative energy. A controller is received within the window and is coupled to the energy emitter such that axial movement of the controller within the window is translated to axial movement of the energy emitter and rotation of the controller within the window is translated into rotation of the energy emitter. The instrument includes a motor that is at least partially disposed within the housing of the catheter; a first gear that is operatively connected to and driven by the motor; and a second gear that is coupled to the energy emitter and is driven by the first gear to cause rotation of the energy emitter, while allowing the energy emitter to move axially.

公开(公告)号：US20220152365A1

公开(公告)日：2022-05-19

申请号：US17532434

申请日：2021-11-22

申请人： CardioFocus, Inc.

发明人： Gerald Melsky ,  Brian Estabrook ,  Lincoln Baxter

IPC分类号： A61M25/10 ,  A61B18/14

摘要： A balloon catheter device with a fluid management system includes a source of balloon fill media and a balloon catheter in fluid communication with the source of balloon fill media. A first conduit is provided for delivering the balloon fill media from the source to the balloon catheter for inflation of a balloon of the catheter device. A second conduit is provided for returning the balloon fill media from the balloon catheter to the source for deflating the balloon. A first pump is disposed along one of the first conduit and the second conduit for pumping the balloon fill media through the respective conduits. The fluid management system operates in three states, namely, (1) a first state in which the balloon fill media is delivered to the balloon for inflation thereof, (2) a second state in which the balloon fill media is removed from the balloon for deflation thereof; and (3) a trapped volume mode in which the balloon fill media is circulated through the balloon so as to maintain an at least substantially constant pressure in the balloon. The fluid management system is configured to maintain a pressure of the balloon between 0.2 psi and 1 psi while maintaining adequate fluid flow to cool the balloon.

公开(公告)号：US20210069479A1

公开(公告)日：2021-03-11

申请号：US17024269

申请日：2020-09-17

申请人： CardioFocus, Inc.

发明人： Sergei Babko-Malyi ,  Brian Estabrook ,  Gerald Melsky ,  Richard Thompson

IPC分类号： A61M25/10

摘要： A method for maintaining a balloon of a balloon catheter at a prescribed pressure of between about 0.2 psi and 1 psi comprises the step of: generating a vacuum within a reservoir defined in a burette that is part of a fluid management system that is configured to controllably inflating and deflating the balloon by circulating balloon fill media along a fluid circuit, wherein generating the vacuum results in formation of a pressure differential along the fluid circuit, thereby allowing the balloon to be maintained at the prescribed pressure between about 0.2 psi and about 1 psi.

公开(公告)号：US10806910B2

公开(公告)日：2020-10-20

申请号：US15953628

申请日：2018-04-16

申请人： CardioFocus, Inc.

发明人： Sergei Babko-Malyi ,  Brian Estabrook ,  Gerald Melsky ,  Richard Thompson

IPC分类号： A61M25/10

摘要： A method for maintaining a balloon of a balloon catheter at a prescribed pressure of between about 0.2 psi and 1 psi comprises the step of: generating a vacuum within a reservoir defined in a burette that is part of a fluid management system that is configured to controllably inflating and deflating the balloon by circulating balloon fill media along a fluid circuit, wherein generating the vacuum results in formation of a pressure differential along the fluid circuit, thereby allowing the balloon to be maintained at the prescribed pressure between about 0.2 psi and about 1 psi.

公开(公告)号：USD851245S1

公开(公告)日：2019-06-11

申请号：US29600753

申请日：2017-04-14

申请人： CardioFocus, Inc.

设计人： Lincoln Baxter ,  Gerald Melsky

公开(公告)号：US20190150718A1

公开(公告)日：2019-05-23

申请号：US16259483

申请日：2019-01-28

申请人： CardioFocus, Inc.

发明人： Gerald Melsky

IPC分类号： A61B1/04 ,  A61B5/00 ,  A61B18/20 ,  A61B1/06

摘要： A system is provided for identifying the sufficiency of lesions formed during a tissue ablation procedure. The system and method include administering an ICG composition to the patient and forming one or more lesions at a surgical site. The method further includes applying energy of a type and in an amount sufficient to cause ICG in the patient to fluoresce. An image of the tissue and lesion at the surgical site is obtained while the ICG fluoresces. The lesion is distinguished from surrounding de novo tissue based on areas of fluorescence to allow a user to evaluate the quality of the lesion.

公开(公告)号：US10154888B2

公开(公告)日：2018-12-18

申请号：US14956052

申请日：2015-12-01

申请人： CardioFocus, Inc.

发明人： Stephen Sagon ,  Gerald Melsky

IPC分类号： A61B90/00 ,  A61B18/20 ,  A61B18/24 ,  A61B1/00 ,  A61B1/313 ,  A61B1/04 ,  A61B5/02 ,  A61B18/00 ,  A61B18/22 ,  A61B90/30

摘要： The present disclosure relates to ablation instruments and methods of use thereof, in particular to ablation catheters and methods for providing visual confirmation of pulmonary isolation during an ablation procedure and preferably, in real-time.