摘要:
A method and an apparatus for mass retrieval for an acoustic pulse generator are disclosed herein. In an impulse type seismic generating apparatus an air spring, mechanical spring, controlled pressurization of an air spring or other energy storage medium is employed to use potential energy to raise the impact mass to a resting position above an earth contacting baseplate as quickly as possible after the impact mass strikes the baseplate.
摘要:
A wire reel holder and dispensing assembly is provided for transporting, holding, and dispensing wire from a wire reel. The holder and assembly includes an elongated shaft configured for insertion through a wire reel. Each of a pair of end members has a polygonal outer perimeter edge and a central opening. The shaft is slidably insertable through the central opening of each end member positioning the end members at each end of the wire reel. Each end member is securable to the shaft to hold the wire reel in a static position along a length of the shaft and prevent rolling of the wire reel on the shaft. A holding assembly is provided for connecting the shaft, end members and wire reel to a vehicle.
摘要:
The present invention provides novel methods of inhibiting pathological conditions related to organ systems which respond to estrogen agonists comprising administering to a mammal in need of such treatment an effective amount of a compound of formula I
摘要:
Prostaglandin agonists, methods of using such prostaglandin agonists, pharmaceutical compositions containing such prostaglandin agonists and kits containing such prostaglandin agonists. The prostaglandin agonists are useful for the treatment of bone disorders including osteoporosis.
摘要:
This invention is directed to pharmaceutical combination compositions and methods comprising (-)-cis-6-phenyl-5-(4-(2-pyrrolidin-1-yl-ethoxy)-phenyl)-5,6,7,8-tetrahydronaphthalene-2-ol or a pharmaceutically acceptable salt thereof and parathyroid hormone or a biologically active fragment thereof, methods of using such compositions and kits containing such compositions. The compositions are useful for treating musculoskeletal frailty, including osteoporosis, osteoporotic fracture, low bone mass and frailty.
摘要:
The present invention provides novel methods of inhibiting bone loss comprising administering to a mammal in need of such treatment an effective amount of a compound of formula I ##STR1## wherein R.sup.1 and R.sup.2 may be the same or different provided that, when R.sup.1 and R.sup.2 are the same, each is a methyl or ethyl group, and, when R.sup.1 and R.sup.2 are different, one of them is a methyl or ethyl group and the other is hydrogen or a benzyl group; or a pharmaceutically acceptable salt thereof; together with a progestin.
摘要:
The present invention provides novel methods of treating or preventing osteoporosis comprising administering to a mammal in need of such treatment an effective amount of a compound of formula I ##STR1## wherein R.sup.1 and R.sup.2 may be the same or different provided that, when R.sup.1 and R.sup.2 are the same, each is a methyl or ethyl group, and, when R.sup.1 and R.sup.2 are different, one of them is a methyl or ethyl group and the other is hydrogen or a benzyl group; or a pharmaceutically acceptable salt thereof; together with a bone resorption inhibiting polyphosphonate.
摘要翻译:本发明提供了治疗或预防骨质疏松症的新方法,包括向需要这种治疗的哺乳动物施用有效量的式I化合物(I),其中R 1和R 2可以相同或不同,条件是当 R 1和R 2相同,各自为甲基或乙基,当R 1和R 2不同时,它们中的一个为甲基或乙基,另一个为氢或苄基; 或其药学上可接受的盐; 以及抑制骨吸收聚膦酸盐的骨吸收。