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公开(公告)号：US11919887B2
公开(公告)日：2024-03-05
申请号：US17982983
申请日：2022-11-08
发明人： Steven John Durrant , Nadia M. Ahmad , Elizabeth Mary Beck , Lidio Marx Carvalho Meireles , Ewa Iwona Chudyk , Gorka Etxebarria Jardi , Bhairavi Galan , Sara S. Hadida Ruah , Dennis James Hurley , Ronald Marcellus Knegtel , Timothy Donald Neubert , Joanne Louise Pinder , Joseph Pontillo , Robert Pullin , Yvonne Schmidt , David Matthew Shaw , Sarah Skerratt , Dean Stamos , Stephen Andrew Thomson , Anisa Nizarali Virani , Christopher Wray
IPC分类号： C07D307/24 , C07D405/12 , C07D405/14
CPC分类号： C07D405/12 , C07D307/24 , C07D405/14 , C07B2200/13
摘要： Compounds, and pharmaceutically acceptable salts thereof, useful as inhibitors of sodium channels are provided. Also provided are pharmaceutical compositions comprising the compounds or pharmaceutically acceptable salts and methods of using the compounds, pharmaceutically acceptable salts, and pharmaceutical compositions in the treatment of various disorders, including pain.
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公开(公告)号：US11802105B2
公开(公告)日：2023-10-31
申请号：US17207975
申请日：2021-03-22
申请人： CORSAIR PHARMA, INC.
IPC分类号： C07C69/734 , C07C69/675 , C07C69/68 , C07D305/08 , C07C69/74 , C07C53/136 , C07C59/11 , C07C59/13 , A61K9/70 , C07D309/08 , C07C69/708 , C07C69/712 , C07C69/75 , C07C69/96 , C07D307/24 , C07C69/28 , C07D307/30
CPC分类号： C07C69/734 , A61K9/7023 , C07C53/136 , C07C59/11 , C07C59/13 , C07C69/28 , C07C69/675 , C07C69/68 , C07C69/708 , C07C69/712 , C07C69/74 , C07C69/75 , C07C69/96 , C07D305/08 , C07D307/24 , C07D307/30 , C07D309/08 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07C2603/14
摘要： The present disclosure provides treprostinil derivatives that can act as prodrugs of treprostinil. The treprostinil derivatives can be used to treat any conditions responsive to treatment with treprostinil, including pulmonary hypertension, such as pulmonary arterial hypertension.
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公开(公告)号：US11760742B2
公开(公告)日：2023-09-19
申请号：US17208474
申请日：2021-03-22
发明人： Kei Yoshida , Takeo Wakita , Hiroyuki Katsuta , Akiyoshi Kai , Yutaka Chiba , Kiyoshi Takahashi , Hiroko Kato , Nobuyuki Kawahara , Michikazu Nomura , Hidenori Daido , Junji Maki , Shinichi Banba
IPC分类号： C07C237/42 , C07D333/38 , A01N37/44 , A01N43/08 , A01N43/10 , A01N43/12 , A01N43/16 , A01N43/30 , A01N43/42 , A01N43/54 , A01N43/56 , A01N43/58 , A01N43/78 , A01N43/80 , C07C317/40 , C07C323/42 , C07C327/48 , C07D207/416 , C07D213/64 , C07D213/73 , C07D213/81 , C07D213/82 , C07D213/89 , C07D215/52 , C07D231/14 , C07D231/16 , C07D239/30 , C07D241/24 , C07D263/34 , C07D275/03 , C07D277/56 , C07D307/24 , C07D307/68 , C07D307/84 , C07D309/08 , C07D309/28 , C07D317/62 , C07D333/68 , A01N43/40 , A01N37/22 , A01N43/60 , C07C237/48 , C07D207/34 , C07D239/28 , C07D261/18 , C07D307/85 , C07D317/46
CPC分类号： C07D333/38 , A01N37/22 , A01N37/44 , A01N43/08 , A01N43/10 , A01N43/12 , A01N43/16 , A01N43/30 , A01N43/40 , A01N43/42 , A01N43/54 , A01N43/56 , A01N43/58 , A01N43/60 , A01N43/78 , A01N43/80 , C07C237/42 , C07C237/48 , C07C317/40 , C07C323/42 , C07C327/48 , C07D207/34 , C07D207/416 , C07D213/64 , C07D213/73 , C07D213/81 , C07D213/82 , C07D213/89 , C07D215/52 , C07D231/14 , C07D231/16 , C07D239/28 , C07D239/30 , C07D241/24 , C07D261/18 , C07D263/34 , C07D275/03 , C07D277/56 , C07D307/24 , C07D307/68 , C07D307/84 , C07D307/85 , C07D309/08 , C07D309/28 , C07D317/46 , C07D317/62 , C07D333/68
摘要： A compound represented by Formula (1):
The compound can be used as insecticides.-
公开(公告)号：US20180265629A1
公开(公告)日：2018-09-20
申请号：US15760973
申请日：2016-09-16
申请人： Micromidas, Inc.
发明人： John Albert BISSELL, II , Makoto Nathanael MASUNO , Alexander Crewe-Read MILLAR , Dimitri A. HIRSCH-WEIL
CPC分类号： C08G63/87 , C07D307/24 , C07D307/68 , C08G63/00 , C08G63/181 , C08G63/672
摘要： Provided herein are methods of producing polymers from furan and optionally diol compounds, using an organocatalyst. The furan compounds may include, for example, 2,5-furandicarboxylic acid or 2,5-tetrahydrofurandicarboxylic acid. Provided herein are also polymer compositions, such as poly(alkylene-2,5-furandicarboxylate). The polymer compositions herein have a low metal content.
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公开(公告)号：US09700543B2
公开(公告)日：2017-07-11
申请号：US14997364
申请日：2016-01-15
发明人： Marcus F. Boehm , Esther Martinborough , Manisha Moorjani , Junko Tamiya , Liming Huang , Thomas Fowler , Andrew Novak , Premji Meghani , Enugurthi Brahmachary , Adam Richard Yeager
IPC分类号： A61K31/4245 , A61K9/00 , A61K47/20 , A61K47/26 , A61K47/40 , A61K47/48 , A61K45/06 , A61K31/155 , A61K38/26 , C07C255/57 , C07D213/79 , C07D213/80 , C07D213/81 , C07D213/82 , C07D309/06 , C07D309/08 , C07D311/16 , C07C271/28 , C07D215/48 , C07D217/02 , C07C275/42 , C07D317/68 , C07D231/12 , C07D333/38 , C07D233/60 , C07C311/08 , C07C311/13 , C07C311/21 , C07D235/06 , C07C311/29 , C07D235/12 , C07D235/18 , C07C311/48 , C07D239/26 , C07D239/28 , C07C317/28 , C07C317/44 , C07D239/74 , C07D413/04 , C07D239/91 , C07D413/12 , C07D241/42 , C07D241/44 , C07D417/12 , C07C323/62 , C07C229/14 , C07D249/08 , C07D257/04 , C07C233/47 , C07C233/51 , C07D261/18 , C07C233/81 , C07C233/83 , C07C235/12 , C07D263/32 , C07C235/38 , C07D263/34 , C07C235/48 , C07D263/48 , C07D263/57 , C07C237/22 , C07C237/36 , C07C237/42 , C07D271/06 , C07D271/07 , C07D271/107 , C07D207/267 , C07D277/30 , C07D209/08 , C07D277/56 , C07D277/66 , C07D279/12 , C07D211/14 , C07D211/34 , C07D211/62 , C07D295/15 , C07D295/155 , C07D295/205 , C07D213/55 , C07D213/65 , C07D307/24 , C07D307/54 , C07D307/68 , C07D307/79 , C08B37/16 , C08L5/16 , B82Y5/00 , A61K31/235 , A61K31/341 , A61K31/4406 , A61K31/4465 , A61K31/495 , A61K31/505 , A61K31/5375 , A61K31/54 , C07D295/24 , A61K31/4439 , A61K31/4725
CPC分类号： A61K31/4245 , A61K9/0019 , A61K9/0095 , A61K31/155 , A61K31/235 , A61K31/341 , A61K31/4406 , A61K31/4439 , A61K31/4465 , A61K31/4725 , A61K31/495 , A61K31/505 , A61K31/5375 , A61K31/54 , A61K38/22 , A61K38/26 , A61K45/06 , A61K47/20 , A61K47/26 , A61K47/40 , A61K47/6951 , B82Y5/00 , C07C229/14 , C07C233/47 , C07C233/51 , C07C233/81 , C07C233/83 , C07C235/12 , C07C235/38 , C07C235/48 , C07C237/22 , C07C237/36 , C07C237/42 , C07C255/57 , C07C271/28 , C07C275/42 , C07C311/08 , C07C311/13 , C07C311/21 , C07C311/29 , C07C311/48 , C07C317/28 , C07C317/44 , C07C323/62 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07D207/267 , C07D209/08 , C07D211/14 , C07D211/34 , C07D211/62 , C07D213/55 , C07D213/65 , C07D213/79 , C07D213/80 , C07D213/81 , C07D213/82 , C07D215/48 , C07D217/02 , C07D231/12 , C07D233/60 , C07D235/06 , C07D235/12 , C07D235/18 , C07D239/26 , C07D239/28 , C07D239/74 , C07D239/91 , C07D241/42 , C07D241/44 , C07D249/08 , C07D257/04 , C07D261/18 , C07D263/32 , C07D263/34 , C07D263/48 , C07D263/57 , C07D271/06 , C07D271/07 , C07D271/107 , C07D277/30 , C07D277/56 , C07D277/66 , C07D279/12 , C07D295/15 , C07D295/155 , C07D295/205 , C07D295/24 , C07D307/24 , C07D307/54 , C07D307/68 , C07D307/79 , C07D309/06 , C07D309/08 , C07D311/16 , C07D317/68 , C07D333/38 , C07D413/04 , C07D413/12 , C07D417/12 , C08B37/0015 , C08L5/16 , A61K2300/00
摘要： Compounds that bind the glucagon-like peptide 1 (GLP-1) receptor, methods of their synthesis, methods of their therapeutic and/or prophylactic use, and methods of their use in stabilizing GLP-1 receptor in vitro for crystallization of the GLP-1 receptor are provided. Certain compounds may have activity as modulators or potentiators with respect to glucagon receptor, GIP receptor, GLP-1 and GLP-2 receptors, and PTH receptor on their own or in the presence of receptor ligands such as GIP(1-42), PTH(1-34), Glucagon(1-29), GLP-2(1-33), GLP-1(7-36), GLP-1(9-36), oxyntomodulin and exendin variants.
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6.发明申请POTENT INHIBITORS OF HUMAN CARBONIC ANHYDRASE II AND BOVINE CARBONIC ANHYDRASE II AND THEIR MECHANISM OF ACTION 审中-公开人碳酸二氢酶II和二氧化碳氢化酶II的药物抑制剂及其作用机理公开(公告)号：US20170073306A1
公开(公告)日：2017-03-16
申请号：US14854981
申请日：2015-09-15
申请人： Muhammad Iqbal Choudhary , Muhammad Saleem , Aamer Saeed Bhatti , Atia-tul Wahab , Ajmal Khan , Atta-ur- Rahman
发明人： Muhammad Iqbal Choudhary , Muhammad Saleem , Aamer Saeed Bhatti , Atia-tul Wahab , Ajmal Khan , Atta-ur- Rahman
IPC分类号： C07C335/26 , C07D307/24
CPC分类号： C07C335/26 , A61K31/17 , C07D307/24
摘要： Inhibitors of carbonic anhydrase-II derived from sulfanilamide are reported.
摘要翻译： 报道了衍生自磺酰胺的碳酸酐酶II的抑制剂。
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公开(公告)号：US20160310471A1
公开(公告)日：2016-10-27
申请号：US14997364
申请日：2016-01-15
申请人： Receptos, Inc.
发明人： Marcus F. Boehm , Esther Martinborough , Manisha Moorjani , Junko Tamiya , Liming Huang , Thomas Fowler , Andrew Novak , Premji Meghani , Enugurthi Brahmachary , Adam Richard Yeager
IPC分类号： A61K31/4245 , A61K31/4439 , A61K31/4725
CPC分类号： A61K31/4245 , A61K9/0019 , A61K9/0095 , A61K31/155 , A61K31/235 , A61K31/341 , A61K31/4406 , A61K31/4439 , A61K31/4465 , A61K31/4725 , A61K31/495 , A61K31/505 , A61K31/5375 , A61K31/54 , A61K38/22 , A61K38/26 , A61K45/06 , A61K47/20 , A61K47/26 , A61K47/40 , A61K47/6951 , B82Y5/00 , C07C229/14 , C07C233/47 , C07C233/51 , C07C233/81 , C07C233/83 , C07C235/12 , C07C235/38 , C07C235/48 , C07C237/22 , C07C237/36 , C07C237/42 , C07C255/57 , C07C271/28 , C07C275/42 , C07C311/08 , C07C311/13 , C07C311/21 , C07C311/29 , C07C311/48 , C07C317/28 , C07C317/44 , C07C323/62 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07D207/267 , C07D209/08 , C07D211/14 , C07D211/34 , C07D211/62 , C07D213/55 , C07D213/65 , C07D213/79 , C07D213/80 , C07D213/81 , C07D213/82 , C07D215/48 , C07D217/02 , C07D231/12 , C07D233/60 , C07D235/06 , C07D235/12 , C07D235/18 , C07D239/26 , C07D239/28 , C07D239/74 , C07D239/91 , C07D241/42 , C07D241/44 , C07D249/08 , C07D257/04 , C07D261/18 , C07D263/32 , C07D263/34 , C07D263/48 , C07D263/57 , C07D271/06 , C07D271/07 , C07D271/107 , C07D277/30 , C07D277/56 , C07D277/66 , C07D279/12 , C07D295/15 , C07D295/155 , C07D295/205 , C07D295/24 , C07D307/24 , C07D307/54 , C07D307/68 , C07D307/79 , C07D309/06 , C07D309/08 , C07D311/16 , C07D317/68 , C07D333/38 , C07D413/04 , C07D413/12 , C07D417/12 , C08B37/0015 , C08L5/16 , A61K2300/00
摘要： Compounds that bind the glucagon-like peptide 1 (GLP-1) receptor, methods of their synthesis, methods of their therapeutic and/or prophylactic use, and methods of their use in stabilizing GLP-1 receptor in vitro for crystallization of the GLP-1 receptor are provided. Certain compounds may have activity as modulators or potentiators with respect to glucagon receptor, GIP receptor, GLP-1 and GLP-2 receptors, and PTH receptor on their own or in the presence of receptor ligands such as GIP(1-42), PTH(1-34), Glucagon(1-29), GLP-2(1-33), GLP-1(7-36), GLP-1(9-36), oxyntomodulin and exendin variants.
摘要翻译： 结合胰高血糖素样肽1（GLP-1）受体的化合物，其合成方法，其治疗和/或预防用途的方法及其在体外稳定GLP-1受体中用于GLP- 1受体。 某些化合物自身或存在受体配体如GIP（1-42），PTH可能具有作为胰高血糖素受体，GIP受体，GLP-1和GLP-2受体以及PTH受体的调节剂或增效剂的活性 （1-34），胰高血糖素（1-29），GLP-2（1-33），GLP-1（7-36），GLP-1（9-36），胃泌酸调节蛋白和毒蜥外泌肽变体。
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公开(公告)号：US09278910B2
公开(公告)日：2016-03-08
申请号：US14122176
申请日：2012-05-31
申请人： Marcus F. Boehm , Esther Martinborough , Manisha Moorjani , Junko Tamiya , Liming Huang , Thomas Fowler , Andrew Novak , Premji Meghani , Enugurthi Brahmachary , Adam Richard Yeager
发明人： Marcus F. Boehm , Esther Martinborough , Manisha Moorjani , Junko Tamiya , Liming Huang , Thomas Fowler , Andrew Novak , Premji Meghani , Enugurthi Brahmachary , Adam Richard Yeager
IPC分类号： C07D271/06 , C07C235/38 , A61K9/00 , A61K47/20 , A61K47/26 , A61K47/40 , A61K47/48 , A61K45/06 , A61K31/155 , A61K38/26 , C07C255/57 , C07D213/79 , C07D213/80 , C07D213/81 , C07D213/82 , C07D309/06 , C07D309/08 , C07D311/16 , C07C271/28 , C07D215/48 , C07D217/02 , C07C275/42 , C07D317/68 , C07D231/12 , C07D333/38 , C07D233/60 , C07C311/08 , C07C311/13 , C07C311/21 , C07D235/06 , C07C311/29 , C07D235/12 , C07D235/18 , C07C311/48 , C07D239/26 , C07D239/28 , C07C317/28 , C07C317/44 , C07D239/74 , C07D413/04 , C07D239/91 , C07D413/12 , C07D241/42 , C07D241/44 , C07D417/12 , C07C323/62 , C07C229/14 , C07D249/08 , C07D257/04 , C07C233/47 , C07C233/51 , C07D261/18 , C07C233/81 , C07C233/83 , C07C235/12 , C07D263/32 , C07D263/34 , C07C235/48 , C07D263/48 , C07D263/57 , C07C237/22 , C07C237/36 , C07C237/42 , C07D271/07 , C07D271/107 , C07D207/267 , C07D277/30 , C07D209/08 , C07D277/56 , C07D277/66 , C07D279/12 , C07D211/14 , C07D211/34 , C07D211/62 , C07D295/15 , C07D295/155 , C07D295/205 , C07D213/55 , C07D213/65 , C07D307/24 , C07D307/54 , C07D307/68 , C07D307/79 , C08B37/16 , C08L5/16 , B82Y5/00 , A61K31/235 , A61K31/341 , A61K31/4406 , A61K31/4465 , A61K31/495 , A61K31/505 , A61K31/5375 , A61K31/54 , C07D295/24
CPC分类号： A61K31/4245 , A61K9/0019 , A61K9/0095 , A61K31/155 , A61K31/235 , A61K31/341 , A61K31/4406 , A61K31/4439 , A61K31/4465 , A61K31/4725 , A61K31/495 , A61K31/505 , A61K31/5375 , A61K31/54 , A61K38/22 , A61K38/26 , A61K45/06 , A61K47/20 , A61K47/26 , A61K47/40 , A61K47/6951 , B82Y5/00 , C07C229/14 , C07C233/47 , C07C233/51 , C07C233/81 , C07C233/83 , C07C235/12 , C07C235/38 , C07C235/48 , C07C237/22 , C07C237/36 , C07C237/42 , C07C255/57 , C07C271/28 , C07C275/42 , C07C311/08 , C07C311/13 , C07C311/21 , C07C311/29 , C07C311/48 , C07C317/28 , C07C317/44 , C07C323/62 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07D207/267 , C07D209/08 , C07D211/14 , C07D211/34 , C07D211/62 , C07D213/55 , C07D213/65 , C07D213/79 , C07D213/80 , C07D213/81 , C07D213/82 , C07D215/48 , C07D217/02 , C07D231/12 , C07D233/60 , C07D235/06 , C07D235/12 , C07D235/18 , C07D239/26 , C07D239/28 , C07D239/74 , C07D239/91 , C07D241/42 , C07D241/44 , C07D249/08 , C07D257/04 , C07D261/18 , C07D263/32 , C07D263/34 , C07D263/48 , C07D263/57 , C07D271/06 , C07D271/07 , C07D271/107 , C07D277/30 , C07D277/56 , C07D277/66 , C07D279/12 , C07D295/15 , C07D295/155 , C07D295/205 , C07D295/24 , C07D307/24 , C07D307/54 , C07D307/68 , C07D307/79 , C07D309/06 , C07D309/08 , C07D311/16 , C07D317/68 , C07D333/38 , C07D413/04 , C07D413/12 , C07D417/12 , C08B37/0015 , C08L5/16 , A61K2300/00
摘要： Compounds that bind the glucagon-like peptide 1 (GLP-1) receptor, methods of their synthesis, methods of their therapeutic and/or prophylactic use, and methods of their use in stabilizing GLP-1 receptor in vitro for crystallization of the GLP-1 receptor are provided. Certain compounds may have activity as modulators or potentiators with respect to glucagon receptor, GIP receptor, GLP-1 and GLP-2 receptors, and PTH receptor on their own or in the presence of receptor ligands such as GIP(1-42), PTH(1-34), Glucagon(1-29), GLP-2(1-33), GLP-1 (7-36), GLP-1 (9-36), oxyntomodulin and exendin variants.
摘要翻译： 结合胰高血糖素样肽1（GLP-1）受体的化合物，其合成方法，其治疗和/或预防用途的方法及其在体外稳定GLP-1受体中用于GLP- 1受体。 某些化合物自身或存在受体配体如GIP（1-42），PTH可能具有作为胰高血糖素受体，GIP受体，GLP-1和GLP-2受体以及PTH受体的调节剂或增效剂的活性 （1-34），胰高血糖素（1-29），GLP-2（1-33），GLP-1（7-36），GLP-1（9-36），胃泌酸调节蛋白和毒蜥外泌肽变体。
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9.发明授权Process for the preparation of triazole antifungal drug, its intermediates and polymorphs thereof 有权制备三唑抗真菌药物的方法，其中间体及其多晶型物公开(公告)号：US09102664B2
公开(公告)日：2015-08-11
申请号：US14345507
申请日：2012-09-17
发明人： Manne Satyanarayana Reddy , Srinivasan Thirumalai Rajan , Sajja Eswaraiah , Sunkara Vishnuvardhan
IPC分类号： C07D405/14 , C07D413/06 , C07D263/24 , C07D307/24 , C07C67/08 , C07C67/31 , C07C67/60 , C07C211/27 , C07C241/04 , C07C251/76 , C07C51/09 , C07C51/487 , C07C59/66 , C07D263/26
CPC分类号： C07D405/14 , C07B2200/07 , C07C51/09 , C07C51/487 , C07C59/66 , C07C67/08 , C07C67/31 , C07C67/60 , C07C211/27 , C07C241/04 , C07C251/76 , C07D263/24 , C07D263/26 , C07D307/24 , C07D413/06 , C07C243/28 , C07C69/734
摘要： A process for the preparation of 4-[4-[4-[4-[[(3R,5R)-5-(2,4-difluorophenyl)tetrahydro-5-(1H-1,2,4-triazol-1-ylmethyl)-3-furanyl]methoxy]phenyl]-1-piperazinyl]phenyl]-2-[(1S,2S)-1-ethyl-2-hydroxypropyl]-2,4-dihydro-3H-1,2,4-triazol-3-one compound of formula-1, its intermediates and polymorphs thereof. (I).
摘要翻译： 制备4- [4- [4- [4 - [[（3R，5R）-5-（2,4-二氟苯基）四氢-5-（1H-1,2,4-三唑-1-基） 甲基）-3-呋喃基]甲氧基]苯基] -1-哌嗪基]苯基] -2 - [（1S，2S）-1-乙基-2-羟丙基] -2,4-二氢-3H- 4-三唑-3-酮，其中间体及其多晶型物。 （一世）。
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公开(公告)号：US08835472B2
公开(公告)日：2014-09-16
申请号：US13211472
申请日：2011-08-17
申请人： Gerald Juergen Roth , Martin Fleck , Niklas Heine , Joerg Kley , Thorsten Lehmann-Lintz , Heike Neubauer , Bernd Nosse
发明人： Gerald Juergen Roth , Martin Fleck , Niklas Heine , Joerg Kley , Thorsten Lehmann-Lintz , Heike Neubauer , Bernd Nosse
IPC分类号： C07D231/14 , C07D277/32 , A61K31/415 , C07C317/44 , C07D207/12 , C07D305/08 , C07D239/26 , C07D213/79 , C07C323/41 , C07C255/46 , C07D239/28 , C07D307/24 , C07D215/12 , C07D413/12 , C07D237/08 , C07D417/12 , C07C271/16 , C07D211/76 , C07C311/10 , C07D217/06 , C07D277/24 , C07D249/10 , C07C237/42 , C07D239/38 , C07C233/20 , C07D213/75 , C07D307/14 , C07D319/08 , C07C275/24 , C07D295/192 , C07C233/05 , C07D233/64 , C07D207/10 , C07D403/04 , C07C255/19 , C07D213/65 , C07C237/22 , C07C233/18 , C07D321/10 , C07C233/60 , C07D405/12 , C07D213/40 , C07C233/47 , C07D253/07 , C07D209/44 , C07D239/42 , C07D261/18 , C07C255/60 , C07D205/08 , C07D213/30 , C07D211/16 , C07D295/088 , C07C233/36 , C07C233/13 , C07D213/82 , C07D309/12 , C07C235/08 , C07D271/08 , C07C233/31 , C07D401/12 , C07D213/64 , C07D261/08 , C07D213/74 , C07D213/643 , C07D263/32 , C07C311/04 , C07D233/90 , C07D231/12 , C07D239/52 , C07D277/28 , C07C235/40 , C07D261/14 , C07D205/04 , C07D263/34 , C07D277/56 , C07C275/40 , C07C233/58 , C07D307/79 , C07D307/68 , C07D209/08 , C07D237/14 , C07D263/58 , C07C311/14 , C07D305/06 , C07D317/62 , C07D239/34 , C07C237/08 , C07D207/325 , C07D401/04
CPC分类号： C07C233/18 , C07B2200/07 , C07C233/05 , C07C233/13 , C07C233/20 , C07C233/31 , C07C233/36 , C07C233/47 , C07C233/58 , C07C233/60 , C07C235/08 , C07C235/40 , C07C237/08 , C07C237/22 , C07C237/42 , C07C255/19 , C07C255/46 , C07C255/60 , C07C271/16 , C07C275/24 , C07C275/40 , C07C311/04 , C07C311/10 , C07C311/14 , C07C317/44 , C07C323/41 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2602/08 , C07D205/04 , C07D205/08 , C07D207/10 , C07D207/12 , C07D207/325 , C07D209/08 , C07D209/44 , C07D211/16 , C07D211/76 , C07D213/30 , C07D213/40 , C07D213/64 , C07D213/643 , C07D213/65 , C07D213/74 , C07D213/75 , C07D213/79 , C07D213/82 , C07D215/12 , C07D217/06 , C07D231/12 , C07D231/14 , C07D233/64 , C07D233/90 , C07D237/08 , C07D237/14 , C07D239/26 , C07D239/28 , C07D239/34 , C07D239/38 , C07D239/42 , C07D239/52 , C07D249/10 , C07D253/07 , C07D261/08 , C07D261/14 , C07D261/18 , C07D263/32 , C07D263/34 , C07D263/58 , C07D271/08 , C07D277/24 , C07D277/28 , C07D277/56 , C07D295/088 , C07D295/192 , C07D305/06 , C07D305/08 , C07D307/14 , C07D307/24 , C07D307/68 , C07D307/79 , C07D309/12 , C07D317/62 , C07D319/08 , C07D321/10 , C07D401/04 , C07D401/08 , C07D401/12 , C07D403/04 , C07D405/12 , C07D413/12 , C07D417/12
摘要： The invention relates to new compounds of the formula I to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.
摘要翻译： 本发明涉及其用作药物的式I的新化合物，其治疗用途的方法和含有它们的药物组合物。
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