公开(公告)号：US06511494B1

公开(公告)日：2003-01-28

申请号：US09715665

申请日：2000-11-17

Applicant: David R. Knighton ,  Vance D. Fiegel

Inventor： David R. Knighton ,  Vance D. Fiegel

IPC: A61B1700

CPC classification number: A61B17/00008 ,  A61B1/018 ,  A61B17/0218 ,  A61B17/29 ,  A61B2017/2926 ,  A61B2017/320044

Abstract: A system for harvesting a section of a blood vessel from a patient's body for further use. The system includes a housing and a removable lower portion that is inserted into an incision to create a workspace for the insertion of tools used to harvest the blood vessel. A multi-lumen body portion is used with various tools to dissect the vein and to protect the vein from any damage during the harvesting procedure. The system can remove a section of the saphenous vein for use in coronary bypass surgery.

Abstract translation: 一种用于从患者身体收获血管的一部分用于进一步使用的系统。 该系统包括壳体和可移除的下部，其插入到切口中以创建用于插入用于收集血管的工具的工作空间。 多腔体部分与各种工具一起使用，以解剖静脉，并在收获过程中保护静脉免受任何损伤。 该系统可以移除隐静脉的一部分用于冠状动脉旁路手术。

公开(公告)号：US06428468B1

公开(公告)日：2002-08-06

申请号：US09586825

申请日：2000-06-05

Applicant: David R. Knighton ,  Vance D. Fiegel

Inventor： David R. Knighton ,  Vance D. Fiegel

IPC: A61F204

CPC classification number: A61B17/00008

Abstract: A device and method for removing a generally cylindrical tissue structure such as a blood vessel from the body of a human or animal. The device includes a body portion having distal and proximal ends with at least one lumen extending longitudinally through the body portion. The lumen is sized to accommodate the vessel and at least one tool used in removing the vessel. Means is provided for isolating the vessel from the tools used in the removal procedure.

Abstract translation: 一种用于从人或动物身体移除大致圆柱形的组织结构（例如血管）的装置和方法。 该装置包括主体部分，该主体部分具有远端和近端，其具有沿主体部分纵向延伸的至少一个内腔。 管腔的尺寸适于容纳容器和用于移除容器的至少一个工具。 提供了用于将容器与用于拆卸程序中的工具隔离的装置。

公开(公告)号：US6071232A

公开(公告)日：2000-06-06

申请号：US107158

申请日：1998-06-29

Applicant: David R. Knighton ,  Vance D. Fiegel

Inventor： David R. Knighton ,  Vance D. Fiegel

IPC: A61B17/00 ,  A61F2/04

CPC classification number: A61B17/00008

Abstract: A system for tissue harvesting comprising a tool to cut a vessel, apply a ligation clip, or remove patient's body fluids and a device for removing a generally cylindrical tissue structure such as a blood vessel from the body of a human or animal. The device includes a body portion having distal and proximal ends with at least one lumen extending longitudinally through the body portion. The lumen is sized to accommodate the vessel and at least one tool used in removing the vessel. Means is provided for isolating the vessel from the tools used in the removal procedure.

Abstract translation: 一种用于组织采集的系统，其包括切割容器的工具，施加连接夹，或移除患者的体液，以及用于从人体或动物身体移除大致圆柱形的组织结构（例如血管）的装置。 该装置包括主体部分，该主体部分具有远端和近端，其具有沿主体部分纵向延伸的至少一个内腔。 管腔的尺寸适于容纳容器和用于移除容器的至少一个工具。 提供了用于将容器与用于拆卸程序中的工具隔离的装置。

公开(公告)号：US20170071213A1

公开(公告)日：2017-03-16

申请号：US15362201

申请日：2016-11-28

Applicant: Vance D. Fiegel ,  David R. Knighton

Inventor： Vance D. Fiegel ,  David R. Knighton

IPC: A01N65/00

CPC classification number: A01N65/00 ,  C02F3/32

Abstract: A method of inhibiting biofilm growth on a surface in an aqueous system comprising contacting a surface susceptible to biofilm growth with a solution comprising an amount of a non-decomposed moss or non-decomposed moss extract effective to inhibit biofilm growth. A method of removing biofilm from a surface in an aqueous system comprising contacting a surface having a biofilm with a solution containing an amount of a non-decomposed moss or non-decomposed moss extract effective to remove some or all of the biofilm from the surface.

Abstract translation: 一种抑制水系统中表面生物膜生长的方法，包括使易受生物膜生长影响的表面与包含一定量的未分解的苔藓或未分解的苔藓提取物的溶液接触，所述溶液有效抑制生物膜生长。 一种从含水体系中的表面除去生物膜的方法，包括将具有生物膜的表面与含有一定量的未分解的苔藓或未分解的苔藓提取物的溶液接触，所述溶液有效地从表面除去一些或全部生物膜。

公开(公告)号：US09005449B2

公开(公告)日：2015-04-14

申请号：US13605377

申请日：2012-09-06

Applicant: David R. Knighton ,  Vance D. Fiegel

Inventor： David R. Knighton ,  Vance D. Fiegel

IPC: C02F1/28 ,  C02F1/76 ,  C02F101/12 ,  C02F101/36 ,  C02F103/42

CPC classification number: G01N33/1826 ,  B01J2220/485 ,  C02F1/286 ,  C02F1/76 ,  C02F3/327 ,  C02F2101/12 ,  C02F2101/36 ,  C02F2103/42 ,  C02F2209/001 ,  C02F2209/003 ,  C02F2209/29 ,  C02F2303/185

Abstract: A method of reducing disinfection by-products in water treated with disinfectants including contacting the water with an amount of a non-decomposed moss effective to reduce the level of disinfection by-products. A method of determining the effectiveness of a first method of reducing disinfection by-products in water treated with disinfectants, the first method including contacting the water with an amount of a non-decomposed moss effective to reduce the level of disinfection by-products, the method including determining the effectiveness of the first method by measuring the level of the disinfection by-products in water treated with disinfectants and contacted with the amount of non-decomposed moss.

Abstract translation: 一种减少用消毒剂处理的水中消毒副产物的方法，包括使水与一定量的未分解苔藓接触，以有效降低消毒副产物的含量。 一种确定在消毒剂处理的水中减少消毒副产物的第一种方法的有效性的方法，第一种方法包括使水与一定量的未分解的苔藓有效以降低消毒副产物的含量， 方法包括通过测量用消毒剂处理的水中的消毒副产物的水平来测定第一种方法的有效性，并与未分解的苔藓的量接触。

公开(公告)号：US20140371522A1

公开(公告)日：2014-12-18

申请号：US14298752

申请日：2014-06-06

Applicant: David R. Knighton ,  Vance D. Fiegel

Inventor： David R. Knighton ,  Vance D. Fiegel

IPC: A61B17/00

CPC classification number: A61B17/00008 ,  A61B2017/00252 ,  A61B2017/00969 ,  A61B2090/306 ,  Y10S623/916 ,  Y10S623/917

Abstract: A tissue illumination system and a method for harvesting a section of a blood vessel from a patient's body for further use. The tissue illumination system includes a light catheter inserted into a lumen of the blood vessel section to illuminate the vessel section and vessel side branches with an intensity which is visible to the physician from an exterior of the vessel section and also includes a viewing element insertable into the lumen and capable of viewing the illuminated vessel section. The tissue illumination system also includes at least one tool insertable into the lumen and used to harvest the vessel section.

Abstract translation: 一种组织照明系统和从患者身体收获血管的一部分以供进一步使用的方法。 组织照明系统包括插入血管部分的内腔中的光导管，用于照射容器部分和容器侧分支，其强度是医生从容器部分外部可见的强度，并且还包括观察元件，其可插入 内腔并且能够观察照明容器部分。 组织照射系统还包括至少一个可插入内腔并用于收获血管部分的工具。

公开(公告)号：US20140147422A1

公开(公告)日：2014-05-29

申请号：US14171186

申请日：2014-02-03

Applicant: Vance D. Fiegel ,  David R. Knighton

Inventor： Vance D. Fiegel ,  David R. Knighton

IPC: C12N5/074 ,  A61K35/44

CPC classification number: C12N5/0607 ,  A61K35/12 ,  A61K35/44 ,  C12N5/069 ,  C12N5/0691 ,  C12N5/0692 ,  C12N2501/135 ,  C12N2501/15

Abstract: A method of deriving isolated stem cells including: implanting a matrix in a wound site of a living organism; allowing cells to infiltrate the matrix; removing the matrix containing the infiltrated cells from the wound site; and removing the infiltrated cells from the matrix to provide isolated stem cells. Stem cells produced by this process, stem cells with certain characteristics, and methods for treating wounds using these stem cells are provided.

Abstract translation: 一种衍生分离的干细胞的方法，包括：将基质植入生物体的伤口部位; 允许细胞渗透基质; 从伤口部位去除含有浸润细胞的基质; 并从基质中除去渗透的细胞以提供分离的干细胞。 提供了通过该方法产生的干细胞，具有某些特征的干细胞，以及使用这些干细胞治疗伤口的方法。

公开(公告)号：US20130319934A1

公开(公告)日：2013-12-05

申请号：US13961219

申请日：2013-08-07

Applicant: David R. Knighton ,  Vance D. Fiegel

Inventor： David R. Knighton ,  Vance D. Fiegel

IPC: C02F3/32

CPC classification number: C02F3/327 ,  A01N65/00 ,  C02F1/50 ,  C02F3/10 ,  C02F3/32 ,  C02F2101/10 ,  C02F2101/20 ,  C02F2103/42 ,  C02F2303/04 ,  E04H4/1281 ,  Y02W10/15 ,  Y02W10/18 ,  A01N25/34

Abstract: A device for use in water comprising a carrier having an interior cavity and one or more openings allowing ingress to and egress from the interior cavity; and a moss contained within the interior cavity in which the carrier completely encloses the moss.

公开(公告)号：US20130126423A1

公开(公告)日：2013-05-23

申请号：US13741800

申请日：2013-01-15

Applicant: David R. Knighton ,  Vance D. Fiegel

Inventor： David R. Knighton ,  Vance D. Fiegel

IPC: C02F3/32

CPC classification number: C02F3/327 ,  A01K63/04 ,  A01N65/00 ,  A01N65/03 ,  A61K36/10 ,  C02F1/286 ,  C02F1/722 ,  C02F3/32 ,  C02F5/00 ,  C02F2101/10 ,  C02F2101/203 ,  C02F2103/42 ,  C02F2303/04 ,  A01N25/34

Abstract: The invention provides a method of inhibiting microorganism growth comprising contacting a substance susceptible to microorganism growth with an amount of a non-decomposed moss effective to inhibit microorganism growth, wherein the moss is selected from the group consisting of sphagnum papillosum, sphagnum cristatum, and mixtures thereof.

公开(公告)号：US20110224483A1

公开(公告)日：2011-09-15

申请号：US13113369

申请日：2011-05-23

Applicant: David R. Knighton ,  Vance D. Fiegel

Inventor： David R. Knighton ,  Vance D. Fiegel

IPC: A61B17/00

CPC classification number: A61B17/00008 ,  A61B2017/00252 ,  A61B2017/00969 ,  A61B2090/306 ,  Y10S623/916 ,  Y10S623/917

Abstract: A tissue illumination system and a method for harvesting a section of a blood vessel from a patient's body for further use. The tissue illumination system includes a light catheter inserted into a lumen of the blood vessel section to illuminate the vessel section and vessel side branches with an intensity which is visible to the physician from an exterior of the vessel section and also includes a viewing element insertable into the lumen and capable of viewing the illuminated vessel section. The tissue illumination system also includes at least one tool insertable into the lumen and used to harvest the vessel section.

Abstract translation: 一种组织照明系统和从患者身体收获血管的一部分以供进一步使用的方法。 组织照明系统包括插入血管部分的内腔中的光导管，用于照射容器部分和容器侧分支，其强度是医生从容器部分外部可见的强度，并且还包括观察元件，其可插入 内腔并且能够观察照明容器部分。 组织照射系统还包括至少一个可插入内腔并用于收获血管部分的工具。