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    USE OF MOSS TO IMPROVE DENTAL HEALTH
    1.
    发明申请
    USE OF MOSS TO IMPROVE DENTAL HEALTH 有权
    使用MOSS改善牙齿健康

    公开(公告)号：US20150174058A1

    公开(公告)日：2015-06-25

    申请号：US14580675

    申请日：2014-12-23

    Applicant: Vance D. Fiegel ,  David R. Knighton

    Inventor： Vance D. Fiegel ,  David R. Knighton

    IPC: A61K8/97

    CPC classification number: A61Q11/00 ,  A61K8/9706 ,  A61K8/9739

    Abstract: A method of improving dental health in a mammal in which a mammal drinks at least 0.5 liters of water per day for a majority of the days of a period of at least one month, the water having been contacted with an amount of a non-decomposed moss effective to improve dental health as evidenced by a reduction in the pocket depths of the teeth of the mammal. A method of improving dental health in a mammal in which the mammal's teeth are brushed using a toothpaste or rinsed with a mouthwash for a majority of the days of a period of at least one month, the toothpaste or mouthwash containing an amount of a non-decomposed moss or non-decomposed moss extract effective to improve dental health as evidenced by a reduction in the pocket depths of the teeth. A toothpaste or mouthwash containing an effective amount of a non-decomposed moss or non-decomposed moss extract.

    Abstract translation: 在哺乳动物中改善牙齿健康的方法，其中哺乳动物在至少一个月的大部分时间内每天饮用至少0.5升的水，所述水已接触一定量的未分解的 苔藓有效地改善牙齿健康，这是通过减少哺乳动物的牙齿的口袋深度所证明的。 一种在哺乳动物中改善牙齿健康的方法，其中使用牙膏刷牙哺乳动物的牙齿或者在至少一个月的大部分时间内用漱口水冲洗，牙膏或漱口剂含有一定量的非牙齿， 分解的苔藓或未分解的苔藓提取物有效地改善牙齿健康，这是通过牙齿凹陷深度的减少所证明的。 含有有效量的未分解苔藓或未分解苔藓提取物的牙膏或漱口水。

    VEIN HARVESTING SYSTEM AND METHOD
    3.
    发明申请
    VEIN HARVESTING SYSTEM AND METHOD 有权
    VEIN收获系统和方法

    公开(公告)号：US20120108891A1

    公开(公告)日：2012-05-03

    申请号：US13348387

    申请日：2012-01-11

    Applicant: David R. Knighton ,  Vance D. Fiegel

    Inventor： David R. Knighton ,  Vance D. Fiegel

    IPC: A61F2/04

    CPC classification number: A61B17/00008 ,  A61B2017/00252 ,  A61B2017/00969 ,  A61B2090/306 ,  Y10S623/916 ,  Y10S623/917

    Abstract: A tissue illumination system and a method for harvesting a section of a blood vessel from a patient's body for further use. The tissue illumination system includes a light catheter inserted into a lumen of the blood vessel section to illuminate the vessel section and vessel side branches with an intensity which is visible to the physician from an exterior of the vessel section and also includes a viewing element insertable into the lumen and capable of viewing the illuminated vessel section. The tissue illumination system also includes at least one tool insertable into the lumen and used to harvest the vessel section.

    Abstract translation: 一种组织照明系统和从患者身体收获血管的一部分以供进一步使用的方法。 组织照明系统包括插入血管部分的内腔中的光导管，用于照射容器部分和容器侧分支，其强度是医生从容器部分外部可见的强度，并且还包括观察元件，其可插入 内腔并且能够观察照明容器部分。 组织照射系统还包括至少一个可插入内腔并用于收获血管部分的工具。

    Vein harvesting system and method
    4.
    发明授权
    Vein harvesting system and method 失效
    静脉收获系统及方法

    公开(公告)号：US07959553B2

    公开(公告)日：2011-06-14

    申请号：US12241316

    申请日：2008-09-30

    Applicant: David R. Knighton ,  Vance D. Fiegel

    Inventor： David R. Knighton ,  Vance D. Fiegel

    IPC: A61F2/04

    CPC classification number: A61B17/00008 ,  A61B2017/00252 ,  A61B2017/00969 ,  A61B2090/306 ,  Y10S623/916 ,  Y10S623/917

    Abstract: A tissue illumination system and a method for harvesting a section of a blood vessel from a patient's body for further use. The tissue illumination system includes a light catheter inserted into a lumen of the blood vessel section to illuminate the vessel section and vessel side branches with an intensity which is visible to the physician from an exterior of the vessel section and also includes a viewing element insertable into the lumen and capable of viewing the illuminated vessel section. The tissue illumination system also includes at least one tool insertable into the lumen and used to harvest the vessel section.

    Abstract translation: 一种组织照明系统和从患者身体收获血管的一部分以供进一步使用的方法。 组织照明系统包括插入血管部分的内腔中的光导管，用于照射容器部分和容器侧分支，其强度是医生从容器部分外部可见的强度，并且还包括观察元件，其可插入 内腔并且能够观察照明容器部分。 组织照射系统还包括至少一个可插入内腔并用于收获血管部分的工具。

    Vein harvesting system and method
    6.
    发明授权
    Vein harvesting system and method 有权
    静脉收获系统及方法

    公开(公告)号：US06705986B2

    公开(公告)日：2004-03-16

    申请号：US10391148

    申请日：2003-03-18

    Applicant: Vance D. Fiegel ,  David R. Knighton

    Inventor： Vance D. Fiegel ,  David R. Knighton

    IPC: A61F204

    CPC classification number: A61B17/00008 ,  A61B2017/00252 ,  A61B2017/00969 ,  A61B2090/306 ,  Y10S623/916 ,  Y10S623/917

    Abstract: A system and a method for harvesting a section of a blood vessel from a patient's body for further use. The system includes an expandable hood that creates a workspace for the dissection and removal of the vessel and a telescoping device that has tools at its distal end. The blood vessel is cut at a distal location and a light catheter inserted to illuminate the area of dissection. The system can remove a section of the saphenous vein for use in coronary bypass surgery.

    Abstract translation: 一种用于从患者身体收获血管的一部分用于进一步使用的系统和方法。 该系统包括可扩张的罩，其产生用于容器的解剖和移除的工作空间和在其远端具有工具的伸缩装置。 在远端位置切割血管，插入光导管照射解剖区域。 该系统可以移除隐静脉的一部分用于冠状动脉旁路手术。

    Endoscope and method for vein removal
    8.
    再颁专利
    Endoscope and method for vein removal 失效
    内窥镜和静脉去除方法

    公开(公告)号：USRE36043E

    公开(公告)日：1999-01-12

    申请号：US585410

    申请日：1996-01-11

    Applicant: David R. Knighton

    Inventor： David R. Knighton

    IPC: A61B1/018 ,  A61B17/00 ,  A61B17/125 ,  A61B1/00

    CPC classification number: A61B17/00008 ,  A61B1/018 ,  A61B2017/00969

    Abstract: An endoscope for use in harvesting blood vessels includes a scope body of the type having a lumen extending longitudinally therethrough which itself has a proximal and a distal end. The endoscope includes means for viewing an area adjacent the distal end of the lumen, and the lumen has a lateral dimension of a size sufficient to accommodate the blood vessel being harvested and at least one tool for use in harvesting the blood vessel. A first end of the blood vessel section to be harvested is exposed through an incision in the patient's body. A dissecting tool and a gripping tool are inserted through the lumen of the endoscope and used to dissect the blood vessel away from the surrounding connective tissue of the patient's body, using the viewing means of the endoscope to view this dissection in process within the patient's body. Additional tools are provided for use through the lumen of the endoscope to remove body fluids and coagulate bleeding tissue, and to sever side branches from the blood vessel to be harvested, as well as to sever a distal end of the blood vessel to be harvested when a desired length of blood vessel has been dissected. Only a single small incision in the patient's body is necessary to harvest a relatively long length of blood vessel in a precise and controlled manner through endoscopic vision using the inventive endoscope and its related tools..Iadd.The questions raised in reexamination request No. 90/004,301, filed Jul. 12, 1996, have been considered and the results thereof are reflected in this reissue patent which constitutes the reexamination certificate required by 35 U.S.C. 307 as provided in 37 CFR 1.570(e). .Iaddend.

    Abstract translation: 用于收集血管的内窥镜包括具有纵向延伸的内腔的本体，其本身具有近端和远端。 所述内窥镜包括用于观察邻近所述腔的远端的区域的装置，并且所述内腔具有足以容纳正在收获的血管的尺寸的横向尺寸和用于收集血管的至少一个工具。 要收获的血管部分的第一端通过患者体内的切口暴露。 解剖工具和夹持工具通过内窥镜的内腔被插入，并且用于使用内窥镜的观察装置将血管从患者身体的周围结缔组织中解剖出来，以在患者体内观察该过程中的该解剖 。 提供了另外的工具用于通过内窥镜的内腔以去除体液并凝结出血组织，并且从被收集的血管切断侧分支以及切断要收获的血管的远端， 已经解剖了所需长度的血管。 通过使用本发明的内窥镜及其相关工具，通过内窥镜视觉，仅需要在患者身体中单个小切口以精确和受控的方式收获相当长的血管。 已经考虑了1996年7月12日提交的第90 / 004,301号复审请求中提出的问题，其结果反映在该重新颁发专利中，该专利构成了35U.S.C.所要求的复审证书。 307如第37 CFR 1.570（e）条所规定。

    Wound healing agents derived from platelets
    9.
    发明授权
    Wound healing agents derived from platelets 失效
    来自血小板的伤口愈合剂

    公开(公告)号：US5165938A

    公开(公告)日：1992-11-24

    申请号：US526542

    申请日：1990-05-18

    Applicant: David R. Knighton

    Inventor： David R. Knighton

    IPC: A61K35/16 ,  A61K47/42 ,  A61L26/00

    CPC classification number: A61L26/0066 ,  A61K35/16 ,  A61K47/42 ,  A61L26/0033 ,  A61L2300/412 ,  A61L2300/64

    Abstract: Platelet enriched plasma is produced from blood. The platelets are activated by thrombin which causes the release of platelet derived growth and angiogenesis factors. A carrier such as a microcrystalline collagen is added to produce a wound treating salve. The compound is applied directly to wounds and initiates healing in non-healing wounds as well as accelerating normal wound healing by increasing vascularization, stimulating fibroblast mitosis and migration and increasing collagen synthesis by fibroblasts. The process of treatment involves the use of a composition containing the materials released by platelets during the platelet release reaction.

    Abstract translation: 富血小板血浆由血液产生。 血小板由凝血酶活化，引起血小板衍生生长和血管生成因子的释放。 加入载体例如微晶胶原以产生伤口治疗药膏。 该化合物直接施用于创伤，并在非愈合伤口中引发愈合，并通过增加血管形成，刺激成纤维细胞有丝分裂和迁移并增加成纤维细胞的胶原合成来加速正常伤口愈合。 治疗过程涉及在血小板释放反应期间使用含有血小板释放的物质的组合物。

    INHIBITION OF BIOFILM FORMATION AND REMOVAL OF BIOFILM BY USE OF MOSS
    10.
    发明申请
    INHIBITION OF BIOFILM FORMATION AND REMOVAL OF BIOFILM BY USE OF MOSS 审中-公开

    公开(公告)号：US20200060287A1

    公开(公告)日：2020-02-27

    申请号：US16669929

    申请日：2019-10-31

    Applicant: Vance D. Fiegel ,  David R. Knighton

    Inventor： Vance D. Fiegel ,  David R. Knighton

    IPC: A01N65/00

    Abstract: A method of inhibiting biofilm growth on a surface in an aqueous system comprising contacting a surface susceptible to biofilm growth with a solution comprising an amount of a non-decomposed moss or non-decomposed moss extract effective to inhibit biofilm growth. A method of removing biofilm from a surface in an aqueous system comprising contacting a surface having a biofilm with a solution containing an amount of a non-decomposed moss or non-decomposed moss extract effective to remove some or all of the biofilm from the surface.

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